Uffe Kristiansen
Associate Professor
Molecular and Cellular Pharmacology
Jagtvej 160
2100 København Ø
- Published
4-PIOL, a low-efficacy partial GABA-A agonist
Frølund, Bente, Kristiansen, Uffe, Nathan, T., Falch, E., Lambert, J. D. C. & Krogsgaard-Larsen, Povl, 1991, Drug Research related to Neuroactive Amino Acids. MunksgaardResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
5-Substituted imidazole-4-acetic acid analogues: Synthesis, modeling, and pharmacological characterization of a series of novel γ-aminobutyric acidC receptor agonists
Madsen, C., Jensen, Anders A., Liljefors, T., Kristiansen, Uffe, Nielsen, Birgitte, Hansen, C. P., Larsen, M., Ebert, B., Bang-Andersen, B., Krogsgaard-Larsen, Povl & Frølund, Bente, 2007, In: Journal of Medicinal Chemistry. 50, p. 4147-4161Research output: Contribution to journal › Journal article › Research › peer-review
- Published
5-substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel ¿-aminobutyric acidC receptor agonists
Madsen, C., Jensen, A. A., Liljefors, T., Kristiansen, Uffe, Nielsen, Birgitte, Hansen, C. P., Larsen, M., Ebert, B., Bang-Andersen, B., Krogsgaard-Larsen, Povl & Frølund, Bente, 2007, In: Journal of Medicinal Chemistry. 50, 17, p. 4147-4161Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Novel Class of Potent 3-Isoxazolol GABAA Antagonists: Design, Synthesis, and Pharmacology
Frølund, Bente, Tagmose, L., Liljefors, T., Stensbøl, T. B., Engblom, C., Kristiansen, Uffe & Krogsgaard-Larsen, Povl, 2000, In: Journal of Medicinal Chemistry. 43, p. 4930–4933Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel class of potent 3-isoxazolol GABAA antagonists: Design, systhesis, and pharmacology [3]
Frølund, Bente, Tagmose, L., Liljefors, T., Stensbøl, T. B., Engblom, C., Kristiansen, Uffe & Krogsgaard-Larsen, Povl, 28 Dec 2000, In: Journal of Medicinal Chemistry. 43, 26, p. 4930-4933 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
A single glycine residue at the entrance to the first membrane-spanning domain of the γ-aminobutyric acid type a receptor β2 subunit affects allosteric sensitivity to GABA and anesthetics
Carlson, B. X., Engblom, A. C., Kristiansen, Uffe, Schousboe, Arne & Olsen, R. W., 2000, In: Molecular Pharmacology. 57, 3, p. 474-484 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of single heteromeric GABAA receptor ion channels by full and partial agonists
Mortensen, M., Kristiansen, Uffe, Ebert, B., Frølund, Bente, Krogsgaard-Larsen, Povl & Smart, T. G., 1 Jun 2004, In: Journal of Physiology. 557, 2, p. 389-413 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation on single heteromeric GABAA receptor Ion channels by full and partial agonists
Mortensen, M., Kristiansen, Uffe, Ebert, B., Frølund, Bente, Krogsgaard-Larsen, Povl & Smart, T., 2004, In: Journal of Physiology. p. 393–417Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute but not delayed amphetamine treatment improves behavioral outcome in a rat embolic stroke model
Rasmussen, Rune Skovgaard, Overgaard, K., Kristiansen, Uffe & Johansen, F. F., Sep 2011, In: Neurological Research. 33, 7, p. 774-782 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An in silico kinetic model of 8-oxo-7,8-dihydro-2-deoxyguanosine and 8-oxo-7,8-dihydroguanosine metabolism from intracellular formation to urinary excretion
Jørgensen, Anders, Thygesen, M. B., Kristiansen, Uffe & Poulsen, Henrik Enghusen, 2021, In: Scandinavian Journal of Clinical and Laboratory Investigation. 81, 7, p. 540-545Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-histamine effect of Rubia tibetica, used to treat anaphylaxis caused by tick bites in the Pamir Mountains, Afghanistan
Jeppesen, A. S., Kristiansen, Uffe, Soelberg, Jens & Jäger, A. K., 14 Jun 2012, In: Journal of Ethnopharmacology. 141, 3, p. 1077-1079 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Anticonvulsive evaluation of THIP in the murine pentylenetetrazole kindling model: lack of anticonvulsive effect of THIP despite functional δ-subunit-containing GABAA receptors in dentate gyrus granule cells
Simonsen, C., Boddum, K., von Schoubye, N. L., Kloppenburg, A., Sønderskov, K., Hansen, S. L. & Kristiansen, Uffe, Aug 2017, In: Pharmacology Research & Perspectives. 5, 4, 15 p., e00322.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Astrocytic GABA transporter activity modulates excitatory neurotransmission
Boddum, K., Jensen, T. P., Magloire, V., Kristiansen, Uffe, Rusakov, D. A., Pavlov, I. & Walker, M. C., 25 Nov 2016, In: Nature Communications. 7, 10 p., 13572.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Benzodiazepine and barbiturate ligands modulate responses of cultured hippocampal neurones to the GABA(A) receptor partial agonist, 4-PIOL
Kristiansen, Uffe & Lambert, J. D. C., 1996, In: Neuropharmacology. 35, 9-10, p. 1181-1191 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholinergic degeneration is associated with increased plaque deposition and cognitive impairment in APPswe/PS1dE9 mice
Laursen, B., Mørk, A., Plath, N., Kristiansen, Uffe & Bastlund, J. F., 1 Mar 2013, In: Behavioural Brain Research. 240, 1, p. 146-52 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 Receptors
Gasiorek, A., Trattnig, S. M., Ahring, P. K., Kristiansen, Uffe, Frølund, Bente, Frederiksen, K. & Jensen, Anders A., 2016, In: Biochemical Pharmacology. 110-111, p. 92-108 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delineation of the functional properties exhibited by the Zinc-Activated Channel (ZAC) and its high-frequency Thr128Ala variant (rs2257020) in Xenopus oocytes
Madjroh, Nawid, Davies, P. A., Smalley, J. L., Kristiansen, Uffe, Söderhielm, P. C. & Jensen, Anders A., 2021, In: Pharmacological Research. 169, 18 p., 105653.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design and synthesis of a new series of 4-alkylated 3-isoxazolol GABAA antagonists
Frølund, Bente, Tagmose, L., Jørgensen, A. T., Kristiansen, Uffe, Stensbøl, T. B., Liljefors, T. & Krogsgaard-Larsen, Povl, 2003, In: European Journal of Medicinal Chemistry. 38, p. 447–449Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design and synthesis of a new series of 4-alkylated 3-isoxazolol GABAA antagonists
Frølund, Bente, Tagmose, L., Jørgensen, A. T., Kristiansen, Uffe, Stensbøl, T. B., Liljefors, T. & Krogsgaard-Larsen, Povl, 1 Apr 2003, In: European Journal of Medicinal Chemistry. 38, 4, p. 447-449 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differences in kinetics of structurally related competitive GABAA receptor antagonists
Vestergaard, H. T., Cannillo, C., Frølund, Bente & Kristiansen, Uffe, 2007, In: Neuropharmacology. 52, 3, p. 873-882Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct Optical Detection of Singlet Oxygen from a Single Cell
Zebger, I., Snyder, J. W., Andersen, L. K., Poulsen, L., Gao, Z., Lambert, J. D. C., Kristiansen, Uffe & Ogilby, P. R., Apr 2004, In: Photochemistry and Photobiology. 79, 4, p. 319-322 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABAA receptors
Falk-Petersen, C. B., Tsonkov, T. M., Nielsen, M. S., Harpsøe, Kasper, Bundgaard, C., Frølund, Bente, Kristiansen, Uffe, Gloriam, David E. & Wellendorph, Petrine, 22 Jun 2020, In: Scientific Reports. 10, 1, 12 p., 10078.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does brain slices from pentylenetetrazole-kindled mice provide a more predictive screening model for antiepileptic drugs?
Hansen, S. L., Sterjev, Z., Werngreen, M., Simonsen, B. J., Knudsen, K. E., Nielsen, A. H., Pedersen, M. E., Badolo, L., Kristiansen, Uffe & Vestergaard, H. T., May 2012, In: European Journal of Pharmacology. 682, 1-3, p. 43-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Rhoicissus digitata extracts on acetylcholine-mediated contraction in rat uterus
Schou, J., Kristiansen, Uffe, Stafford, G. I., van Heerden, F. & Jäger, A., Aug 2010, In: Planta Medica. 76, 12, p. 1217Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Effect of acute injections of the ketone bodies in PTZ kindled mice
Hansen, S. L., Riisberg, M., Nouri-Nejad, A., Skonberg, C., Kristiansen, Uffe & Hansen, Harald S., 2008.Research output: Contribution to conference › Poster › Research
ID: 985515
Most downloads
-
182
downloads
Increasing cellular lifespan with a flow system in organotypic culture of the Laterodorsal Tegmentum (LDT)
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
181
downloads
Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABAA receptors
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
169
downloads
Astrocytic GABA transporter activity modulates excitatory neurotransmission
Research output: Contribution to journal › Journal article › Research › peer-review
Published