Tina Vilsbøll

Tina Vilsbøll

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


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  1. Published

    Women with prior gestational diabetes mellitus and prediabetes are characterised by a decreased incretin effect

    Foghsgaard, S., Vedtofte, L., Andreasen, C., Andersen, E. S., Bahne, E., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Knop, Filip Krag & Vilsbøll, Tina, Jul 2017, In: Diabetologia. 60, 7, p. 1344-1353 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Use of insulin providers versus insulin sensitizers and risk of out-of-hospital cardiac arrest - a nationwide case-time-control study

    Mohr, G. H., Sondergaard, K. B., Pallisgaard, J. L., Weeke, P., Jensen, Aksel Karl Georg, Rajan, S., Lippert, F. K., Torp-Pedersens, C., Vilsbøll, Tina & Gislason, Gunnar Hilmar, 2017, In: European Heart Journal Supplements. 38, Supplement 1, p. 425-426 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  3. Published

    Use of antibiotics in childhood and risk of Type 1 diabetes: a population-based case-control study

    Mikkelsen, K. H., Knop, Filip Krag, Vilsbøll, Tina, Frost, M., Hallas, J. & Pottegård, A., Feb 2017, In: Diabetic Medicine. 34, 2, p. 272–277

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Understanding the place for GLP-1RA therapy: Translating guidelines for treatment of type 2 diabetes into everyday clinical practice and patient selection

    Andreasen, C. R., Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetes, Obesity and Metabolism. 23, S3, p. 40-52 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  5. Published

    Understanding Biosimilar Insulins - Development, Manufacturing, and Clinical Trials

    Heinemann, L., Davies, M., Home, P., Forst, T., Vilsbøll, Tina & Schnell, O., 2023, In: Journal of Diabetes Science and Technology. 17, 6, p. 1649-1661 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Typical Danish Caucasian type 2 diabetic patients do not commonly carry genetic variants in GIP and GLP-1 encoding regions of the proGIP and proglucagon genes

    Ørskov, C., Hjorth, S. A., Jensen, A. & Vilsbøll, Tina, 15 Jul 2004, In: Regulatory Peptides. 119, 3, p. 151-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Type 2 Diabetes Patients Reach Target Glycemic Control Faster Using IDegLira than Either Insulin Degludec or Liraglutide Given Alone

    Vilsbøll, Tina, Vora, J., Jarlov, H., Kvist, K. & Blonde, L., 2016, In: Clinical Drug Investigation. 36, 4, p. 293-303 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose- and non-glucose-induced insulin secretion in patients with type 2 diabetes mellitus

    Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-333 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Twelve weeks treatment with the DPP-4 inhibitor sitagliptin improves glycaemic control, but does not improve GLP-1 secretion, in patients with type 2 diabetes - a randomised trial

    Aaboe, K., Knop, F. K., Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2009, In: Diabetologia. p. 748

    Research output: Contribution to journal › Conference abstract in journal › Research

  10. Published

    Tværsektorielt samarbejde ved behandling af patienter med type 2-diabetes

    Munch, L., Røder, M. E., Rasmussen, I. H., Middelfart, H., Kaarsberg, N., Bennich, B., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Ugeskrift for Laeger. 180, 8, p. 690-693

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Trends in One-Year Outcomes of Dialysis-Requiring Acute Kidney Injury in Denmark 2005-2012: A Population-Based Nationwide Study

    Carlson, N., Hommel, K., Olesen, J. B., Soja, A., Vilsbøll, Tina, Kamper, A., Torp-Pedersen, C. & Gislason, Gunnar Hilmar, 2016, In: PLOS ONE. 11, 7, p. 1-14 14 p., e0159944.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists

    Hansen, K. B., Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, Tina, 2009, In: International Journal of Clinical Practice. 63, 8, p. 1154-60 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Transitioning from basal–bolus or premix insulin therapy to a combination of basal insulin and glucagon-like peptide-1 receptor agonist in people with type 2 diabetes

    Mehta, R., Billings, L. K., Liebl, A. & Vilsbøll, Tina, 2022, In: Diabetic Medicine. 39, 9, e14901.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Transforming Motivation for Exercise in a Safe and Kind Environment—A Qualitative Study of Experiences among Individuals with Type 2 Diabetes

    Nielsen, S. G., Danielsen, J. H., Grønbæk, H. N., Mølsted, Stig, Jacobsen, S. S., Vilsbøll, Tina & Varming, A. R., 2022, In: International Journal of Environmental Research and Public Health. 19, 10, 12 p., 6091.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Therapy for obesity based on gastrointestinal hormones

    Bagger, J. I., Christensen, M., Knop, Filip Krag & Vilsbøll, Tina, 2011, In: Review of Diabetic Studies. 8, 3, p. 339-47 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The spectrum of antidiabetic actions of GLP-1 in patients with diabetes

    Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2009, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 23, 4, p. 453-62 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes

    Lund, Asger Bach, Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 6, p. E1038-E1046 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The role of the incretins in the postprandial bone remodelling

    Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S221-S221 449.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  19. Published

    The role of glucagon in the acute therapeutic effects of SGLT2 inhibition

    Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetes. 69, 12, p. 2619-2629 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The role of endogenous GIP and GLP-1 in postprandial bone homeostasis

    Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Bergmann, N. C., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, Mette & Knop, Filip Krag, 2020, In: Bone. 140, 7 p., 115553.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The role of GLP-1 in the postprandial effects of acarbose in type 2 diabetes

    Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Hansen, L. S., Hansen, N. L., Stensen, S., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: European Journal of Endocrinology. 184, 3, p. 387-398 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The quality of dietary carbohydrate and fat is associated with better metabolic control in persons with type 1 and type 2 diabetes

    Jacobsen, S. S., Vistisen, D., Vilsbøll, Tina, Bruun, J. M. & Ewers, B., 2020, In: Nutrition Journal. 19, 125.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype

    Vilsbøll, Tina, Knop, Filip Krag, Krarup, T., Johansen, A., Madsbad, Sten, Larsen, S., Hansen, T., Pedersen, O., Holst, J. M. & Johansen, A., 1 Oct 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 10, p. 4897-903 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance

    van Poppel, P. C. M., van Asseldonk, E. J. P., Holst, Jens Juul, Vilsbøll, Tina, Netea, M. G. & Tack, C. J., Dec 2014, In: Diabetes, Obesity and Metabolism. 16, 12, p. 1269-73 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  25. Published

    The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.

    Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2007, In: Regulatory Peptides. 144, 1-3, p. 123-30 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    The incretin system and its role in type 2 diabetes mellitus

    Holst, Jens Juul, Vilsbøll, Tina & Deacon, Carolyn F., 2008, In: Molecular and Cellular Endocrinology. 297, 1-2, p. 127-136 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The impact of pancreatic enzyme supplementation on postprandial responses of glucagon-like Peptide-2 in patients with chronic pancreatitis and pancreatic exocrine insufficiency

    Knop, Filip Krag, Vilsbøll, Tina, Lund, A., Krarup, T., Holst, Jens Juul & Hornum, Mads, 6 Sep 2010, In: Journal of the Pancreas. 11, 5, p. 489-91 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The impact of acute glycaemic fluctuations on left ventricular systolic function in insulin-treated type 2 diabetes

    Andersen, A., Jorgensen, P. G., Bagger, J. I., Baldassarre, M. P. A., Christensen, M., Abelin, K. U., Faber, Jens, Pedersen-Bjergaard, Ulrik, Holst, Jens Juul, Lindhardt, T., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetologia. 63, SUPPL 1, p. S429-S429 897.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  29. Published

    The impact of acute fluctuations in plasma glucose on echocardiographic derived measures of systolic function in patients with type 1 diabetes

    Andreasen, C. R., Andersen, A., Haqelqvist, P. G., Abelin, K., Lauritsen, J. V., Jorgensen, P. G., Engberg, S., Faber, Jens, Holst, Jens Juul, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetologia. 64, SUPPL 1, p. 135-136 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  30. Published

    The impact of EndoBarrier gastrointestinal liner in obese patients with normal glucose tolerance and in patients with type 2 diabetes

    Rohde, U., Federspiel, C. A., Vilmann, Peter, Langholz, Ebbe, Friis, S. U., Krakauer, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 189-199 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The glucose-lowering effect of the bile acid sequestrant sevelamer in patients with type 2 diabetes is not mediated by glucagon-like peptide 1

    Nerild, H. H., Brønden, Andreas, Haddouchi, A. E., Holst, Jens Juul, Sonne, D. P., Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 217-217 422.

    Research output: Contribution to journal › Conference abstract in journal › Research

  32. Published

    The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action

    Hare, K. J., Vilsbøll, Tina, Asmar, M., Deacon, Carolyn F., Knop, Filip Krag & Holst, Jens Juul, 1 Jul 2010, In: Diabetes. 59, 7, p. 1765-70 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The glucagon receptor antagonist LY2409021 does not affect gastrointestinal-mediated glucose disposal or the incretin effect in individuals with and without type 2 diabetes

    Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., Forman, Julie Lyng, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 187, 4, p. 507-518 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The future of incretins in the treatment of obesity and non-alcoholic fatty liver disease

    Andreasen, C. R., Andersen, A. & Vilsbøll, Tina, 2023, In: Diabetologia. 66, p. 1846-1858 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  35. Published

    The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.

    Vilsbøll, Tina, Agersø, H., Lauritsen, T., Deacon, Carolyn F., Aaboe, K., Madsbad, Sten, Krarup, T. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 137, 3, p. 168-72 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The efficacy and safety of exenatide once weekly in patients with type 2 diabetes

    Heimburger, S. M., Brønden, Andreas, Johansen, N. J., Dejgaard, T. F., Vilsbøll, Tina & Knop, Filip Krag, 2019, In: Expert Opinion on Pharmacotherapy. 20, 5, p. 501-510

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The effects of glucagon-like peptide-1 on the beta cell

    Vilsbøll, Tina, 2009, In: Diabetes, Obesity and Metabolism. 11 Suppl 3, p. 11-18 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The effects of dual GLP-1/GIP receptor agonism on glucagon secretion: a review

    Mathiesen, D. S., Bagger, J. I., Bergmann, N. C., Lund, A., Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2019, In: International Journal of Molecular Sciences. 20, 17, 18 p., 4092.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    The effect of exogenous glucagon on circulating amino acids in individuals with and without type 2 diabetes and obesity

    Grøndahl, M. F. G., Bagger, J. I., Suppli, M. P., van Hall, Gerrit, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring, Lund, A. B. & Knop, Filip Krag, 2024, In: Endocrine Connections. 13, 3, 7 p., e230516.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The effect of empagliflozin on oxidative nucleic acid modifications in patients with type 2 diabetes: Protocol for a randomised, double-blinded, placebo-controlled trial

    Larsen, E. L., Cejvanovic, V., Kjær, L. K., Vilsbøll, Tina, Knop, Filip Krag, Rungby, Jørgen & Poulsen, Henrik Enghusen, May 2017, In: BMJ Open. 7, 5, 6 p., e014728.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    The effect of curcumin on hepatic fat content in individuals with obesity

    Hellmann, P. H., Bagger, J. I., Carlander, K. R., Forman, Julie Lyng, Chabanova, E., Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2192-2202 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The effect of acute intragastric vs. intravenous alcohol administration on inflammation markers, blood lipids and gallbladder motility in healthy men

    Lanng, A. R., Gasbjerg, Lærke Smidt, Bergmann, N. C., Gillum, M. P., Rehfeld, Jens Frederik, Helsted, M. M., Møller, H. J., Grønbæk, H., Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Alcohol. 87, p. 29-37 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The effect of 6-day subcutaneous glucose-dependent insulinotropic polypeptide infusion on time in glycaemic range in patients with type 1 diabetes: a randomised, double-blind, placebo-controlled crossover trial

    Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2021, In: Diabetologia. 64, p. 2425-2431

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The dietary education trial in carbohydrate counting (DIET-CARB Study): Study protocol for a randomised, parallel, open-label, intervention study comparing different approaches to dietary self-management in patients with type 1 diabetes

    Ewers, B., Vilsbøll, Tina, Andersen, H. U. & Bruun, J. M., 2019, In: BMJ Open. 9, 9, 8 p., e029859.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The bile acid-sequestering resin sevelamer eliminates the acute GLP-1 stimulatory effect of endogenously released bile acids in patients with type 2 diabetes

    Brønden, A., Albér, A., Rohde, U., Gasbjerg, Lærke Smidt, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Feb 2018, In: Diabetes, Obesity and Metabolism. 20, 2, p. 362-369

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    The alpha-cell as target for type 2 diabetes therapy

    Christensen, M., Bagger, J. I., Vilsbøll, Tina & Knop, Filip Krag, 2011, In: Review of Diabetic Studies. 8, 3, p. 369-81 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men

    Pilgaard, K., Jensen, C., Schou, J., Lyssenko, V., Wegner, L., Brøns, C., Vilsbøll, T., Hansen, T., Madsbad, S., Holst, J., Vølund, A., Poulsen, P., Groop, L., Pedersen, O., Vaag, A., Pilgaard, K., Jensen, C. B., Schou, J. H., Lyssenko, V., Wegner, L. & 10 others, Brøns, C., Vilsbøll, T., Hansen, T., Madsbad, Sten, Holst, J. M., Vølund, A., Poulsen, P., Groop, L., Pedersen, O. & Vaag, A., 1 Jul 2009, In: Diabetologia. 52, 7, p. 1298-307 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The Role of Glucagon in the Pathophysiology and Treatment of Type 2 Diabetes

    Hædersdal, S., Lund, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Mayo Clinic Proceedings. 93, 2, p. 217-239

    Research output: Contribution to journal › Review › Research › peer-review

  49. Published

    The Gut-Bone Axis in Diabetes

    Maagensen, H., Helsted, M. M., Gasbjerg, Lærke Smidt, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Current Osteoporosis Reports. 21, p. 21–31 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  50. Published

    The Glucagon Receptor Antagonist LY2409021 has No Effect on Postprandial Glucose in Type 2 Diabetes

    Hædersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Forman, Julie Lyng, van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 186, 2, p. 207-221 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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