Thomas Mandel Clausen

Thomas Mandel Clausen

Guest Researcher

Member of:

  • VAR2CSA team

ORCID: 0000-0001-7543-9622

Publication year:
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  1. Published

    Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates

    Karlsson, R., Chopra, P., Joshi, A., Yang, Zhang, Vakhrushev, Sergey, Clausen, Thomas Mandel, Painter, C. D., Szekeres, G. P., Chen, Yen-Hsi, Sandoval, D. R., Hansen, Lars, Esko, J. D., Pagel, K., Dyer, D. P., Turnbull, Jeremy Ewan, Clausen, Henrik, Boons, G. J. & Miller, Rebecca Louise, 2021, In: Science Advances. 7, 52, eabl6026.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate

    Weiss, R. J., Spahn, P. N., Chiang, A. W. T., Liu, Q., Li, J., Hamill, K. M., Rother, S., Clausen, Thomas Mandel, Hoeksema, M. A., Timm, B. M., Godula, K., Glass, C. K., Tor, Y., Gordts, P. L. S. M., Lewis, N. E. & Esko, J. D., 2021, In: Nature Chemical Biology. 17, p. 684–692

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Identification of global inhibitors of cellular glycosylation

    Sørensen, D. M., Büll, C., Madsen, T. D., Lira-Navarrete, E., Clausen, T. M., Clark, A. E., Garretson, A. F., Karlsson, R., Pijnenborg, J. F. A., Yin, X., Miller, R. L., Chanda, S. K., Boltje, T. J., Schjoldager, K. T., Vakhrushev, S. Y., Halim, A., Esko, J. D., Carlin, A. F., Hurtado-Guerrero, R., Weigert, R. & 2 others, Clausen, Henrik & Narimatsu, Yoshiki, 2023, In: Nature Communications. 14, 1, 19 p., 948.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Molecular dissection of placental malaria protein VAR2CSA interaction with a chemo-enzymatically synthesized chondroitin sulfate library

    Sugiura, N., Clausen, Thomas Mandel, Shioiri, T., Gustavsson, Tobias, Watanabe, H. & Salanti, Ali, Dec 2016, In: Glycoconjugate Journal. 33, 6, p. 985-994 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Noninvasive detection of any-stage cancer using free glycosaminoglycans

    Bratulic, S., Limeta, A., Dabestani, S., Birgisson, H., Enblad, G., Stålberg, K., Hesselager, G., Häggman, M., Höglund, M., Simonson, O. E., Stålberg, P., Lindman, H., Bång-Rudenstam, A., Ekstrand, M., Kumar, G., Cavarretta, I., Alfano, M., Pellegrino, F., Mandel-Clausen, T., Salanti, A. & 16 others, Maccari, F., Galeotti, F., Volpi, N., Daugaard, M., Belting, M., Lundstam, S., Stierner, U., Nyman, J., Bergman, B., Edqvist, P., Levin, M., Salonia, A., Kjölhede, H., Jonasch, E., Nielsen, J. & Gatto, F., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 50, p. e2115328119

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Oncofetal chondroitin sulfate glycosaminoglycans are key players in integrin signaling and tumor cell motility

    Clausen, Thomas Mandel, Bento Ayres Pereira, M. M., Al Nakouzi, N., Oo, H. Z., Agerbæk, Mette Ørskov, Lee, S., Ørum-Madsen, M. S., Kristensen, A. R., El-Naggar, A., Grandgenett, P. M., Grem, J. L., Hollingsworth, M. A., Holst, Peter Johannes, Theander, Thor Grundtvig, Sorensen, P. H., Daugaard, M. & Salanti, Ali, Dec 2016, In: Molecular Cancer Research. 14, 12, p. 1288-1299 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Oncofetal chondroitin sulfate is a highly expressed therapeutic target in non-small cell lung cancer

    Oo, H. Z., Lohinai, Z., Khazamipour, N., Lo, J., Kumar, G., Pihl, J., Adomat, H., Nabavi, N., Behmanesh, H., Zhai, B., Dagil, R., Choudhary, S., Gustavsson, T., Clausen, T. M., Esko, J. D., Allen, J. W., Thompson, M. A., Tran, N. L., Moldvay, J., Dome, B. & 4 others, Salanti, Ali, Al-Nakouzi, N., Weiss, G. J. & Daugaard, M., 2021, In: Cancers. 13, 17, 16 p., 4489.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1

    Ayres Pereira, M., Clausen, Thomas Mandel, Pehrson, Caroline, Mao, Y., Resende, M., Daugaard, M., Riis Kristensen, A., Spliid, C. B., Mathiesen, Line, Knudsen, Lisbeth E., Damm, Peter, Theander, Thor Grundtvig, R Hansson, S., Nielsen, Morten Agertoug & Salanti, Ali, Aug 2016, In: P L o S Pathogens. 12, 8, 26 p., e1005831.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting

    Clausen, Thomas Mandel, Ayres Pereira, M., Oo, H. Z., Resende, M., Gustavsson, Tobias, Mao, Y., Sugiura, N., Liew, J., Fazli, L., Theander, Thor Grundtvig, Daugaard, M. & Salanti, Ali, Jul 2016, In: Sensing and Bio-Sensing Research. 9, p. 23-30 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer

    Al Nakouzi, N., Wang, C. K., Oo, H. Z., Nelepcu, I., Lallous, N., Spliid, C. B., Khazamipour, N., Lo, J., Truong, S., Collins, C., Hui, D., Esfandnia, S., Adomat, H., Clausen, T. M., Gustavsson, T., Choudhary, S., Dagil, R., Corey, E., Wang, Y., Chauchereau, A. & 6 others, Fazli, L., Esko, J. D., Salanti, Ali, Nelson, P. S., Gleave, M. & Daugaard, M., 2022, In: Nature Communications. 13, 4760.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 35054027