Lisbeth E. Knudsen

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Primary fields of research

Responsible for toxicology, human biomonitoring and ethics reated to human studies

Elected member of the Faculty Academic council

Previously study director of bachelor and master of science studies in Public Health Sciences at the Faculty of Health and Medicine.

Current research

Research

Toxicology, genotoxicology, biomonitoring of environmental and occupational exposures and early effects, ethical aspects of genetic testing, susceptibility markers and susceptible groups, Alternatives to animal studies
 
Projects

European Human Biomonitoring Initiative -HBM4EU - Horizon2020 program contract No 733032. Linked Third Party via NRCWE focusing on ethics and the national hub contact point

Human Eksposure to PCB in buildings. HBM projekt with National Research Center on Building and the National Ress earch Center on Working Environment

Past projects

BRIDGE-Health (BRidging information and Data Generation) for Evidence-based Health Policy and Research) aims to create European health information (EU-HI) and data generation networks covering major EU health policy areas. Project no.: 664691. 2015 -

Pesticidmålinger i urin - etablering af analysemetode og analyse af urinprøver fra danske mødre og børn indsamlet som en del af DEMOCOPHES projektet. KOntrakt opgave for Miljøstyrelsen koordineret af SDU og i samarbejde med VITO, Belgien

Review of the state of the art of human biomonitoring for chemical subtances and its application to human exposure assessment for food safety. EFSA contract by BiPro 2014

Human exposure to novel flame retardants from materials to humans (NO FLAME). DFF post doc bevilling til Marie Frederiksen, Statens Byggeforskningsinstitut, Aalborg Universitet

COPHES: (COnsortium to Perform Human biomonitoring on a European Scale) FP7 2009-2013, half of the expenses for sampling and analysis nationally to be covered by DEMOCOPHES  EU Life+ and further funding from the ministries of Health, Food and environment each contributing with 1/6^th of the expenses (2009-2013).

Endocrine disruption by pesticides. Research financed by the Environmental Protection Agency Pesticide Fund (2009-2013).

Toxicology in vitro in Denmark: Danish Network in vitro toxicology and alternative methods (2008-2011).

Nanotest Development of methodology for alternative testing strategies for the assessment of the toxicological profile of nanoparticles used in medical diagnostics. A Collaborative Project. Small or medium-scale focused research project, under FP7 (2008-2011).

Polybrominated diphenyl ethers (PBDEs) - fetal and neonatal exposure. Project in collaboration with the National Environmental Institute and partly financed by the Danish Medical Research Council (2007-2009).

NEWGENERIS Newborns and genotoxic exposure risks: Development and application of biomarkers of dietary exposure to genotoxic and immunotoxic chemicals and of biomarkers of early effects, using mother-child birth cohorts and bio banks (EU Integrated Project). LEK is partner with placenta perfusion, samples for biomarker analysis and ethics. (2006-2011).

ESBIO Expert team to Support BIO monitoring specific support action to support a pilot project with biomonitoring in EU www.eu-humanbiomonitoring.org (2005-2007).

Placental transport of pesticides. Research financed by the Environmental Protection Agency Pesticide Fund (2006-2008).

ReProTect: Development of a novel approach in hazard and risk assessment of reproductive toxicity by combination and application of in vitro, tissue and sensor technology. EU Integrated Project. (2004-2009). LEK was partner no 32 with placenta perfusion, biomonitoring and ethics. ecvam.jrc.it/ft_doc/ReProTect%20summary_final.pdf

Teaching

PhD supervision

Tina Mose: development and optimization of an ex-vivo human placental perfusion system – Placental transfer of chemical compounds. 2009.

Marie Frederiksen: Human exposure to polybrominated diphenyl ethers. An exposure study of pregnant women and their un- and newborn children. 2010.

Marie Pedersen: Transplacental exposure to environmental pollutants. Biomarkers of exposures and effects in blood from mother-newborn pairs. 2010.

Mia B. Kjærstad: Potential endocrine disturbance of fetal development by azole compounds used as antifungals in pharmaceuticals and agrochemicals – a study on placental transport and effects on steroid receptors and steroid metabolizing enzymes. 2011.

Line Mathiesen: Active transport across human placenta. Defence 25.8.2011.

Thit Aarøe Mørck: Exposures to environmental toxicants amongst schoolchildren and their mothers. From December 2010.

Caroline Pehrsson Placental malaria, free fetal haemoglobin and preeclampsia in collaboration with Thor Theander, Peter Damm and Stefan Hansson. 2016.