Sten Madsbad

Sten Madsbad

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


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  1. Published

    Fixed-ratio combination therapy with GLP-1 receptor agonist liraglutide and insulin degludec in people with type 2 diabetes

    Østergaard, L., Frandsen, C. S., Dejgaard, T. F. & Madsbad, Sten, Jun 2017, In: Expert Review of Clinical Pharmacology. 10, 6, p. 621-632 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  2. Published

    Treatment potential of the GLP-1 receptor agonists in type 2 diabetes mellitus: a review

    Østergaard, L., Frandsen, C. S. & Madsbad, Sten, 2016, In: Expert Review of Clinical Pharmacology. 9, 2, p. 241-65 25 p.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Effect of weight reductions on estimated kidney function: Post-hoc analysis of two randomized trials

    von Scholten, B. J., Davies, M. J., Persson, F., Hansen, T. W., Madsbad, Sten, Endahl, L., Jepsen, C. H. & Rossing, Peter, 2017, In: Journal of Diabetes and its Complications. 31, 7, p. 1164-1168

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Effect of large weight reductions on measured and estimated kidney function

    von Scholten, B. J., Persson, F., Svane, M. S., Hansen, T. W., Madsbad, Sten & Rossing, Peter, 6 Feb 2017, In: B M C Nephrology. 18, 7 p., 52.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study.

    Olsen, Ane Mette Zander, Madsbad, Sten, Madsen, J. L. & Holst, Jens Juul, 2002, In: Lancet. 359, 9309, p. 824-30 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose leves in patients with type 2 diabetes.

    Zander, M., Madsbad, Sten, Deacon, C. & Holst, J., 2006, In: Diabetologia. 49, p. 369-374 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Additive effects of glucagon-like peptide 1 and pioglitazone in patients with type 2 diabetes.

    Olsen, Ane Mette Zander, Christiansen, A., Madsbad, Sten & Holst, Jens Juul, 2004, In: Diabetes Care. 27, 8, p. 1910-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes

    Zander, M., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 369-74 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Additive glucose-lowering effects of glucagon-like peptide-1 and metformin in type 2 diabetes.

    Zander, M., Taskiran, M., Toft-Nielsen, M. B., Madsbad, Sten & Holst, J. J., 2001, In: Diabetes Care. 24, 4, p. 720-725 6 p.

    Research output: Contribution to journal › Journal article › Research

  10. Published

    Kinetics of insulin and C-peptide and estimation of prehepatic insulin secretion rates after intravenous glucose stimulation using arterial versus venous blood sampling in healthy males

    Wriedt, E. B., Kielgast, U., Svane, M. S., Møller, Søren & Madsbad, Sten, 2024, In: Scandinavian Journal of Clinical and Laboratory Investigation. 84, 1, p. 16-23 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Changes in Hematology and Calcium Metabolism After Gastric Bypass Surgery: a 2-Year Follow-Up Study

    Worm, D., Madsbad, Sten, Kristiansen, V. B., Naver, L. & Hansen, D. L., Sep 2015, In: Obesity Surgery. 25, 9, p. 1647-52 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Metabolic Health in Severely Obese Subjects: A Descriptive Study

    Worm, Dorte, Madsbad, Sten & Hansen, D. L., Mar 2019, In: Metabolic Syndrome and Related Disorders. 17, 2, p. 115-119 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Prediction of carotid intima-media thickness and its relation to cardiovascular events in persons with type 2 diabetes

    Winckler, K., Thorsteinsson, B., Wiinberg, N., Jensen, Andreas Kryger, Lundby-Christensen, L., Heitmann, Berit, Lund, S. S., Krarup, T., Jensen, T., Vestergaard, H., Breum, Leif, Sneppen, S., Boesgaard, T., Madsbad, Sten, Gluud, C., Vaag, A., Almdal, Thomas Peter, Tarnow, L. & The CIMT trial group, T. C. T. G., Oct 2020, In: Journal of Diabetes and its Complications. 34, 10, 107681.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    On measurements of glucagon secretion in healthy, obese, and Roux-en-Y gastric bypass operated individuals using sandwich ELISA

    Albrechtsen, Nicolai Jacob Wewer, Kjeldsen, Sasha Alexandra Sampson, Jensen, N. J., Rungby, Jørgen, Veedfald, Simon, Bojsen-Møller, K. N., Dirksen, C., Jensen, Christian Zinck, Martinussen, C., Madsbad, Sten & Holst, Jens Juul, 2022, In: Scandinavian Journal of Clinical & Laboratory Investigation. 82, 1, p. 75-83

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Acute effects on glucose tolerance by neprilysin inhibition in patients with type 2 diabetes

    Albrechtsen, Nicolai Jacob Wewer, Møller, A., Martinussen, C., Gluud, Lise Lotte, Rashu, E. B., Richter, Michael Martin, Plomgaard, Peter Stendahl, Goetze, Jens P. , Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2022, In: Diabetes, Obesity and Metabolism. 24, 10, p. 2017-2026 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite

    Albrechtsen, Nicolai Jacob Wewer, Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, Rune Ehrenreich, Asmar, M., Veedfald, Simon, Plamboeck, A., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Nauck, M. A., Deacon, Carolyn F., Bülow, J., Holst, Jens Juul & Hartmann, Bolette, 1 Sep 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, p. E284-E291

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery

    Albrechtsen, Nicolai Jacob Wewer, Geyer, P. E., Doll, S., Treit, P. V., Bojsen-Møller, K. N., Martinussen, C., Jørgensen, N. B., Torekov, Signe Sørensen, Meier, F., Niu, Lili, Santos, A., Keilhauer, E. C., Holst, Jens Juul, Madsbad, Sten & Mann, Matthias, 2018, In: Cell Systems. 7, 6, p. 601-612

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Cross-Validation of a Glucose-Insulin-Glucagon Pharmacodynamics Model for Simulation Using Data From Patients With Type 1 Diabetes

    Wendt, S. L., Ranjan, A., Møller, J. K., Schmidt, S., Knudsen, C. B., Holst, Jens Juul, Madsbad, Sten, Madsen, H., Nørgaard, Kirsten & Jørgensen, J. B., 1 Nov 2017, In: Journal of Diabetes Science and Technology. 11, 6, p. 1101-1111 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Den endokrine og metaboliske kobling mellem COVID-19, diabetes og fedme

    Weis, Nina, Thorsteinsson, K., Martinussen, C. & Madsbad, Sten, 2020, In: Ugeskrift for Laeger. 182, 29, 9 p., V05200381.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Effects of carbohydrate restriction on body weight and glycemic control in individuals with type 2 diabetes: A randomized controlled trial of efficacy in real-life settings

    Weber, P., Thomsen, M. N., fbg982, fbg982, Samkani, A., Carl, M. H., Astrup, A., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Madsbad, Sten, Magkos, Faidon, Krarup, T. & Haugaard, Steen Bendix, 2022, In: Nutrients. 14, 24, 12 p., 5244.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Relationship Between Two Common Lipoprotein Lipase Variants and the Metabolic Syndrome and Its Individual Components

    Vishram, J. K. K., Hansen, T. W., Torp-Pedersen, C., Madsbad, Sten, Jørgensen, T., Fenger, M., Lyngbæk, S. & Jeppesen, J., Nov 2016, In: Metabolic Syndrome and Related Disorders. 14, 9, p. 442-448 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus

    Vilsbøll, Tina, Krarup, T., Sonne, J., Madsbad, Sten, Vølund, A., Juul, Anders, Holst, J. M. & Juul, A. G., 1 Jun 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 6, p. 2706-13 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Liraglutide, a long-acting human glucagon-like peptide-1 analog, given as monotherapy significantly improves glycemic control and lowers body weight without risk of hypoglycemia in patients with type 2 diabetes

    Vilsbøll, Tina, Zdravkovic, M., Le-Thi, T., Krarup, T., Schmitz, O., Courrèges, J., Verhoeven, R., Bugánová, I. & Madsbad, Sten, 1 Jun 2007, In: Diabetes Care. 30, 6, p. 1608-10 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects

    Vilsbøll, Tina, Krarup, T., Madsbad, Sten & Holst, J. J., 15 Jul 2003, In: Regulatory Peptides. 114, 2-3, p. 115-121 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    No reactive hypoglycaemia in type 2 diabetic patients after subcutaneous administration of GLP-1 and intravenous glucose

    Vilsbøll, Tina, Krarup, T., Madsbad, Sten & Holst, Jens Juul, 1 Feb 2001, In: Diabetic Medicine. 18, 2, p. 144-149 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Evaluation of beta-cell secretory capacity using glucagon-like peptide 1

    Vilsbøll, Tina, Nielsen, M. T., Krarup, T., Madsbad, Sten, Dinesen, B. I. & Holst, J. M., 1 Jun 2000, In: Diabetes Care. 23, 6, p. 807-12 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic B-cell function and arginine-stimulated insulin secretion during hyperglycaemia in patients with Type 2 diabetes mellitus

    Vilsbøll, Tina, Brock, B., Perrild, H., Levin, K., Lervang, H., Kølendorf, K. E., Krarup, T., Schmitz, O., Zdravkovic, M., Le Thi Thanh, X. & Madsbad, Sten, 1 Feb 2008, In: Diabetic Medicine. 25, 2, p. 152-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients

    Vilsbøll, Tina, Krarup, T., Madsbad, Sten & Holst, J. M., 1 Aug 2002, In: Diabetologia. 45, 8, p. 1111-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.

    Vilsbøll, Tina, Agersø, H., Lauritsen, T., Deacon, Carolyn F., Aaboe, K., Madsbad, Sten, Krarup, T. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 137, 3, p. 168-72 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype

    Vilsbøll, Tina, Knop, Filip Krag, Krarup, T., Johansen, A., Madsbad, Sten, Larsen, S., Hansen, T., Pedersen, O., Holst, J. M. & Johansen, A., 1 Oct 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 10, p. 4897-903 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients

    Vilsbøll, Tina, Krarup, T., Deacon, C. F., Madsbad, Sten & Holst, J. M., 1 Mar 2001, In: Diabetes. 50, 3, p. 609-613 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects

    Vilsbøll, T., Krarup, T., Madsbad, Sten & Holst, Jens Juul, 15 Jul 2003, In: Regulatory Peptides. 114, 2-3, p. 115-21 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus

    Vilsbøll, T., Krarup, T., Sonne, J., Madsbad, Sten, Vølund, A., Juul, A. G. & Holst, Jens Juul, Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2706-13 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Increased glucose-stimulated FGF21 response to oral glucose in obese non-diabetic subjects after Roux-en-Y Gastric Bypass

    Vienberg, S. G., Jacobsen, S. H., Worm, D., Hvolris, L. E., Naver, L. P. S., Almdal, Thomas Peter, Hansen, D. L., Wulff, B. S., Clausen, T. R., Madsbad, Sten, Holst, Jens Juul & Andersen, B., Jan 2017, In: Clinical Endocrinology. 86, 1, p. 156-159 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Major rapid weight loss induces changes in cardiac repolarization

    Vedel-Larsen, E., Iepsen, E. P. W., Lundgren, J., Graff, C., Struijk, J. J., Hansen, Torben, Holst, Jens Juul, Madsbad, Sten, Torekov, Signe Sørensen & Kanters, Jørgen K., 10 Feb 2016, In: Journal of Electrocardiology. 49, 3, p. 467-472 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    In vivo and in vitro degradation of peptide YY3-36 to inactive peptide YY3-34 in humans

    Toräng, S., Bojsen-Møller, K. N., Svane, M. S., Hartmann, Bolette, Rosenkilde, Mette, Madsbad, Sten & Holst, Jens Juul, 27 Jan 2016, In: A J P: Regulatory, Integrative and Comparative Physiology (Online). 310, 1, p. R866-R874 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1

    Torekov, S. S., Ma, L., Grarup, N., Hartmann, B., Hainerová, I. A., Kielgast, U., Kissow, H., Rosenkilde, M., Lebl, J., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Madsen, O. D., Wang, J., Linneberg, A., Madsbad, S., Holst, J. J., Hansen, T., Pedersen, O. & 1 others, GIANT Consortium, G. C., 2011, In: Diabetologia. 54, 11, p. 2820-31 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Obesity - an indication for GLP-1 treatment? Obesity pathophysiology and GLP-1 treatment potential

    Torekov, Signe Sørensen, Madsbad, Sten & Holst, Jens Juul, 2011, In: Obesity Reviews. 12, 8, p. 593-601 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The effect of glucagon-like peptide I (GLP-I) on glucose elimination in healthy subjects depends on the pancreatic glucoregulatory hormones.

    Toft-Nielson, M., Madsbad, Sten & Holst, J. J., 1996, In: Diabetes. 45, 5, p. 552-556 5 p.

    Research output: Contribution to journal › Journal article › Research

  40. Published

    Determinants of the effectiveness of glucagon-like peptide-1 in type 2 diabetes.

    Toft-Nielsen, M. B., Madsbad, Sten & Holst, J. J., 2001, In: Journal of Clinical Endocrinology and Metabolism. 86, 8, p. 3853-3860 8 p.

    Research output: Contribution to journal › Journal article › Research

  41. Published

    Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients.

    Toft-Nielsen, M. B., Madsbad, Sten & Holst, J. J., 1999, In: Diabetes Care. 22, 7, p. 1137-1143 7 p.

    Research output: Contribution to journal › Journal article › Research

  42. Published

    Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients

    Toft-Nielsen, M. B., Damholt, M. B., Madsbad, Sten, Hilsted, L. M., Hughes, T. E., Michelsen, B. K. & Holst, Jens Juul, 2001, In: Journal of Clinical Endocrinology and Metabolism. 86, 8, p. 3717-3723 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Exaggerated secretion of glucagon-like peptide-1 (GLP-1) could cause reactive hypoglycaemia

    Toft-Nielsen, M., Madsbad, Sten & Holst, Jens Juul, 1998, In: Diabetologia. 41, 10, p. 1180-1186 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Effects of Roux-en-Y Gastric Bypass on Fasting and Postprandial Levels of the Inflammatory Markers YKL-40 and MCP-1 in Patients with Type 2 Diabetes and Glucose Tolerant Subjects

    Thomsen, S. B., Rathcke, C. N., Jørgensen, N. B., Madsbad, Sten & drb459, drb459, 2013, In: International Journal of Obesity. 2013, 10 p., 361781.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The clinical effects of a carbohydrate-reduced high-protein diet on glycaemic variability in metformin-treated patients with type 2 diabetes mellitus: A randomised controlled study

    Thomsen, M. N., fbg982, fbg982, Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Haugaard, Steen Bendix & Samkani, A., 2020, In: Clinical Nutrition ESPEN. 39, p. 46-52 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial

    Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2022, In: Frontiers in Nutrition. 9, 14 p., 933118.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes: A randomised controlled trial

    Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Chabanova, E., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Haugaard, Steen Bendix & Krarup, T., 2022, In: Diabetologia. 65, p. 506-517 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Long-term outcomes of dietary carbohydrate restriction for HbA1c reduction in type 2 diabetes mellitus are needed. Reply to Kang J and Ma E [letter]

    Thomsen, M. N., Astrup, A., Holst, Jens Juul, Madsbad, Sten, Magkos, Faidon, Haugaard, Steen Bendix & Krarup, T., 2022, In: Diabetologia. 65, 6, p. 1060-1062 3 p.

    Research output: Contribution to journal › Comment/debate › Research

  49. Published

    Reduced carbohydrate and increased protein and fat in the diet augment the positive effect of weight loss on glucose control in type 2 diabetes patients

    Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Larsen, T. M., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Thomsen, Henrik S., Chabanova, E., Madsbad, Sten, Haugaard, Steen Bendix & Krarup, T., 2020, In: Diabetologia. 63, Suppl. 1, p. S295-S296 614.

    Research output: Contribution to journal › Conference abstract in journal › Research

  50. Published

    Reduced carbohydrate and increased protein and fat during weight loss improve the atherogenic lipid profile in type 2 diabetes

    Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Chabanova, E., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Walzem, R. L., Krarup, T. & Haugaard, Steen Bendix, 2021, In: Diabetologia. 64, SUPPL 1, p. 60-60 109.

    Research output: Contribution to journal › Conference abstract in journal › Research

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