Sten Madsbad
Clinical Professor
Department of Clinical Medicine
Kettegård Allé 30, 2650 Hvidovre
Member of:
Internal Medicine: Endocrinology
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Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors
Aaboe, K., Akram, S., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jan 2015, In: Diabetes, Obesity and Metabolism. 17, 1, p. 74-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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K-ATP Channel Closure Ameliorates the Impaired Insulinotropic Effect of Glucose-Dependent Insulinotropic Polypeptide in Patients with Type 2 Diabetes
Aaboe, K., Knop, K., Vilsboll, T., Volund, A., Simonsen, U., Deacon, C. F., Madsbad, Sten, Holst, J. J. & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Twelve weeks treatment with the DPP-4 inhibitor sitagliptin improves glycaemic control, but does not improve GLP-1 secretion, in patients with type 2 diabetes - a randomised trial
Aaboe, K., Knop, F. K., Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2009, In: Diabetologia. p. 748Research output: Contribution to journal › Conference abstract in journal › Research
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GLP-1: physiological effects and potential therapeutic applications
Aaboe, K., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Aaboe, K., Krarup, T., Madsbad, Sten & Holst, J. J., 2008, In: Diabetic Medicine. 10, 11, p. 994-1003 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GLP-1: physiological effects and potential therapeutic applications
Aaboe, K., Krarup, T., Madsbad, Sten & Holst, Jens Juul, Nov 2008, In: Diabetes, Obesity and Metabolism Online. 10, 11, p. 994-1003 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes
Aaboe, K., Knop, Filip Krag, Vilsboll, T., Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes
Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608Research output: Contribution to journal › Journal article › Research › peer-review
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Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose- and non-glucose-induced insulin secretion in patients with type 2 diabetes mellitus
Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-333 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Determinants of Weight Loss After Bariatric Surgery
Aasbrenn, M., Schnurr, T. M., Have, C. T., Svendstrup, M., Hansen, D. L., Worm, Dorte, Balslev-Harder, M., Hollensted, M., Grarup, Niels, Burgdorf, K. S., drb459, drb459, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A., Fenger, M., Madsbad, Sten & Hansen, Torben, 2019, In: Obesity Surgery. 29, 8, p. 2554-2561 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic markers of abdominal obesity and weight loss after gastric bypass surgery
Aasbrenn, M., Svendstrup, M., Schnurr, T. M., Hansen, D. L., Worm, Dorte, Balslev-Harder, M., Grarup, Niels, Burgdorf, Kristoffer Sølvsten, drb459, drb459, Pedersen, Oluf Borbye, Ängquist, Lars, Fenger, M., Sørensen, Thorkild I.A., Madsbad, Sten & Hansen, Torben, 2021, In: PLoS ONE. 16, 5, 11 p., 0252525.Research output: Contribution to journal › Journal article › Research › peer-review
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Link Between GIP and Osteopontin in Adipose Tissue and Insulin Resistance
Ahlqvist, E., Osmark, P., Kuulasmaa, T., Pilgaard, K., Omar, B., Brøns, C., Kotova, O., Zetterqvist, A. V., Stancáková, A., Jonsson, A. E., Hansson, O., Kuusisto, J., Kieffer, T. J., Tuomi, T., Isomaa, B., Madsbad, S., Gomez, M. F., Poulsen, P., Laakso, M., Degerman, E. & 5 others, , Jun 2013, In: Diabetes. 62, 6, p. 2088-94 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enhanced insulin signaling in human skeletal muscle and adipose tissue following gastric bypass surgery
Albers, P. H., Bojsen-Moller, K. N., Dirksen, C., Serup, A. K., Kristensen, D. E., Frystyk, J., Clausen, T. R., Kiens, Bente, Richter, Erik A., Madsbad, Sten & Wojtaszewski, Jørgen F P, 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 309, 5, p. R510-R524 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, , Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460Research output: Contribution to journal › Journal article › Research › peer-review
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Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?
Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Veedfald, Simon, Windeløv, Johanne Agerlin, Plamboeck, A., Bojsen-Møller, K. N., Idorn, T., Feldt-Rasmussen, Bo, Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, 3 Jun 2014, In: Diabetologia. 57, 9, p. 1919-1926 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of a self-prepared carbohydrate-reduced high-protein diet on cardiovascular disease risk markers in patients with type 2 diabetes
Alzahrani, A. H., Skytte, M. J., Samkani, A., Thomsen, M. N., Astrup, A., Ritz, C., Frystyk, J., Holst, Jens Juul, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T., Larsen, T. M. & Magkos, Faidon, 2021, In: Nutrients. 13, 5, 10 p., 1694.Research output: Contribution to journal › Journal article › Research › peer-review
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Body weight and metabolic risk factors in patients with type 2 diabetes on a self-selected high-protein low-carbohydrate diet
Alzahrani, A. H. A., Skytte, M. J., Samkani, A., Thomsen, M. N., Astrup, A., Ritz, C., Chabanova, E., Frystyk, J., Holst, Jens Juul, Thomsen, Henrik S., Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T., Larsen, T. M. & Magkos, Faidon, 2021, In: European Journal of Nutrition. 60, 8, p. 4473-4482 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Studies of the Gly482Ser polymorphism of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) gene in Danish subjects with the metabolic syndrome
Ambye, L., Rasmussen, S., Fenger, M., Jørgensen, T., Borch-Johnsen, K., Madsbad, Sten & Urhammer, S., 2005, In: Diabetes Research and Clinical Practice. 67, 2, p. 175-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial
Andersen, E., Juhl, C. R., Kjøller, E. T., Lundgren, J. R., Janus, C., Dehestani, Y., Saupstad, M., Ingerslev, L. R., Duun, O. M., Jensen, Simon Birk Kjær, Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten, Torekov, Signe Sørensen & Barrès, Romain, May 2022, In: Human Reproduction. 37, 7, p. 1414–1422 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enhanced glucagon-like peptide-1 (GLP-1) response to oral glucose in glucose-intolerant HIV-infected patients on antiretroviral therapy
Andersen, Ove, Haugaard, Steen Bendix, Holst, Jens Juul, Deacon, Carolyn F., Iversen, J., Andersen, U. B., Nielsen, J. O. & Madsbad, Sten, Mar 2005, In: HIV Medicine. 6, 2, p. 91-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Circulating sex hormones and gene expression of subcutaneous adipose tissue oestrogen and alpha-adrenergic receptors in HIV-lipodystrophy: implications for fat distribution.
Andersen, Ove, Pedersen, S. B., Svenstrup, B., Hansen, B. R., Paulsen, S. K., Rathje, G. S., Richelsen, B., Nielsen, J. O., Madsbad, Sten, Iversen, J. & Haugaard, S. B., 2007, In: Clinical Endocrinology. 67, 2, p. 250-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipodystrophy in human immunodeficiency virus patients impairs insulin action and induces defects in beta-cell function
Andersen, Ove, Haugaard, S. B., Andersen, U. B., Friis-Møller, N., Storgaard, H., Vølund, A., Nielsen, J. O., Iversen, J. & Madsbad, Sten, 2003, In: Metabolism. 52, 10, p. 1343-53 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sustained low-dose growth hormone therapy optimizes bioactive insulin-like growth factor-I level and may enhance CD4 T-cell number in HIV infection
Andersen, Ove, Hansen, B. R., Troensegaard, W., Flyvbjerg, A., Madsbad, Sten, Ørskov, H., Nielsen, J. O., Iversen, J. & Haugaard, S. B., 2010, In: Journal of Medical Virology. 82, 2, p. 197-205 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Low-dose growth hormone and human immunodeficiency virus-associated lipodystrophy syndrome: a pilot study
Andersen, Ove, Haugaard, S. B., Flyvbjerg, A., Andersen, U. B., Ørskov, H., Madsbad, Sten, Nielsen, J. O. & Iversen, J., 2004, In: European Journal of Clinical Investigation. 34, 8, p. 561-568 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Different growth hormone sensitivity of target tissues and growth hormone response to glucose in HIV-infected patients with and without lipodystrophy
Andersen, Ove, Haugaard, S. B., Hansen, B. R., Orskov, H., Andersen, U. B., Madsbad, Sten, Iversen, J. & Flyvbjerg, A., 2004, In: Scandinavian Journal of Infectious Diseases. 36, 11-12, p. 832-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enhanced glucagon-like peptide-1 (GLP-1) response to oral glucose in glucose-intolerant HIV-infected patients on antiretroviral therapy.
Andersen, Ove, Haugaard, S. B., Holst, J. J., Deacon, C. F., Iversen, J., Andersen, U. B., Nielsen, J. O., Madsbad, Sten, Haugaard, S. B. & Nielsen, J. O., 2005, In: HIV Medicine. 6, 2, p. 91-98 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preanalytical handling of samples for measurement of plasma lactate in HIV patients
Andersen, Ove, Jørgensen, L. T., Sørensen, S., Nielsen, J. O., Haugaard, S. B., Madsbad, Sten & Iversen, J., 2003, In: Scandinavian Journal of Clinical & Laboratory Investigation. 63, 6, p. 449-454 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Liraglutide improves the beta-cell function without increasing insulin secretion during a mixed meal in patients, who exhibit well-controlled type 2 diabetes and coronary artery disease
Anholm, C., Kumarathurai, P., Jurs, A., Pedersen, L. R., Nielsen, Olav Wendelboe, Kristiansen, O. P., Fenger, M., Holst, Jens Juul, Madsbad, Sten, Sajadieh, Ahmad & Haugaard, Steen Bendix, 2019, In: Diabetology & Metabolic Syndrome. 11, 12 p., 42.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of liraglutide on estimates of lipolysis and lipid oxidation in obese patients with stable coronary artery disease and newly diagnosed type 2 diabetes: A randomized trial
Anholm, C., Kumarathurai, P., Samkani, A., Pedersen, L. R., Boston, R. C., Nielsen, Olav Wendelboe, Kristiansen, O. P., Fenger, M., Madsbad, Sten, Sajadieh, Ahmad & Haugaard, Steen Bendix, 2019, In: Diabetes, Obesity and Metabolism. 21, 8, p. 2012-2016 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adding liraglutide to the backbone therapy of biguanide in patients with coronary artery disease and newly diagnosed type-2 diabetes (the AddHope2 study): a randomised controlled study protocol
Anholm, C., Kumarathurai, P., Klit, M. S., Kristiansen, O. P., Nielsen, Olav Wendelboe, Ladelund, S., Madsbad, Sten, Sajadieh, Ahmad & Haugaard, Steen Bendix, 2014, In: B M J Open. 4, 7, p. 1-10 10 p., e005942.Research output: Contribution to journal › Journal article › Research › peer-review
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Liraglutide effects on beta-cell, insulin sensitivity and glucose effectiveness in patients with stable coronary artery disease and newly diagnosed type 2 diabetes
Anholm, C., Kumarathurai, P., Pedersen, L. R., Nielsen, Olav Wendelboe, Kristiansen, O. P., Fenger, M., Madsbad, Sten, Sajadieh, Ahmad & Haugaard, Steen Bendix, 2017, In: Diabetes, Obesity and Metabolism. 19, 6, p. 850-857Research output: Contribution to journal › Journal article › Research › peer-review
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Liraglutide in combination with metformin may improve the atherogenic lipid profile and decrease C-reactive protein level in statin treated obese patients with coronary artery disease and newly diagnosed type 2 diabetes: A randomized trial
Anholm, C., Kumarathurai, P., Pedersen, L. R., Samkani, A., Walzem, R. L., Nielsen, Olav Wendelboe, Kristiansen, O. P., Fenger, M., Madsbad, Sten, Sajadieh, Ahmad & Haugaard, Steen Bendix, Sep 2019, In: Atherosclerosis. 288, p. 60-66 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of baseline characteristics and beta-cell function on the efficacy and safety of subcutaneous once-weekly semaglutide: A patient-level, pooled analysis of the SUSTAIN 1-5 trials
Aroda, V. R., Capehorn, M. S., Chaykin, L., Frias, J. P., Lausvig, N. L., Macura, S., Lüdemann, J., Madsbad, Sten, Rosenstock, J., Tabak, O., Tadayon, S. & Bain, S. C., 2020, In: Diabetes, Obesity and Metabolism. 22, 3, p. 303-314Research output: Contribution to journal › Journal article › Research › peer-review
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Extracellular Fluid Volume Expansion Uncovers a Natriuretic Action of GLP-1: A Functional GLP-1–Renal Axis in Man
Asmar, A., Cramon, P. K., Simonsen, L., Asmar, M., Sorensen, Charlotte Mehlin, Madsbad, Sten, Moro, C., Hartmann, Bolette, Jensen, B. L., Holst, Jens Juul & Bülow, J., Jul 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2509–2519Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 does not have acute effects on central or renal hemodynamics in patients with type 2 diabetes without nephropathy
Asmar, A., Simonsen, L., Asmar, M., Madsbad, Sten, Holst, Jens Juul, Frandsen, E., Moro, C., Sorensen, Charlotte Mehlin, Jonassen, Thomas & Bulow, J., May 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 310, 9, p. E744-E753 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Renal Extraction and Acute Effects of Glucagon-like peptide-1 on Central and Renal Hemodynamics in Healthy Men
Asmar, A., Simonsen, L., Asmar, M., Madsbad, Sten, Holst, Jens Juul, Frandsen, E., Moro, C., Jonassen, Thomas & Bülow, J., 15 Apr 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 8, p. E641-E649 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 elicits vasodilation in adipose tissue and skeletal muscle in healthy men
Asmar, A., Asmar, M., Simonsen, L., Madsbad, Sten, Holst, Jens Juul, Hartmann, Bolette, Sorensen, Charlotte Mehlin & Bülow, J., Feb 2017, In: Physiological Reports. 5, 3, 12 p., e13073.Research output: Contribution to journal › Journal article › Research › peer-review
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The Renal Extraction and the Natriuretic Action of GLP-1 in Humans Depend on Interaction With the GLP-1 Receptor
Asmar, A., Cramon, P. K., Asmar, M., Simonsen, L., Sorensen, Charlotte Mehlin, Madsbad, Sten, Hartmann, Bolette, Holst, Jens Juul, Hovind, P., Jensen, B. L. & Bülow, J., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 1, p. e11-e19 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased oral sodium chloride intake in humans amplifies selectively postprandial GLP-1 but not GIP, CCK, and gastrin in plasma
Asmar, A., Cramon, P. K., Asmar, M., Simonsen, L., Sorensen, Charlotte Mehlin, Madsbad, Sten, Moro, C., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Hovind, P., Jensen, B. L. & Bülow, J., 2020, In: Physiological Reports. 8, 15, 11 p., e14519.Research output: Contribution to journal › Journal article › Research › peer-review
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Human amylin, pramlintide and GLP-1: Influence on gastric emptying, appetite and food intake in humans
Asmar, M., Knop, F. K., Bache, M., Vilsboll, T., Madsbad, Sten & Holst, J. J., 2008, In: Diabetes. 57, Suppl. 1, p. A406-A407Research output: Contribution to journal › Journal article › Research › peer-review
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On the role of glucose-dependent insulintropic polypeptide in postprandial metabolism in humans
Asmar, M., Tangaa, W., Madsbad, Sten, Hare, K., Astrup, A., Flint, A., Bülow, J. & Holst, Jens Juul, 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 3, p. E614-21 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes
Asmar, M., Højberg, P. V., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-80 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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New physiological effects of incretin hormones GLP-1 and GIP
Madsbad, Sten, 2010, Hvidovre Hospital. 56 p.Research output: Book/Report › Ph.D. thesis › Research
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Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?
Asmar, M., Bache, M., Knop, Filip Krag, Madsbad, Sten & Holst, Jens Juul, 1 May 2010, In: The Journal of clinical endocrinology and metabolism. 95, 5, p. 2367-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucose-dependent insulinotropic polypeptide may enhance fatty acid re-esterification in subcutaneous abdominal adipose tissue in lean humans
Asmar, M., Simonsen, L., Madsbad, Sten, Stallknecht, Bente Merete, Holst, Jens Juul & Bülow, J., 1 Sep 2010, In: Diabetes. 59, 9, p. 2160-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pancreatic ß-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes
Asmar, M., Højberg, P., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-180 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial
Astrup, A., Madsbad, Sten, Breum, Leif, Jensen, T. J., Kroustrup, J. P. & Larsen, T. M., 2008, In: Lancet. 372, 9653, p. 1906-1913 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of tesofensine on weight loss: results from a one-armed, open-labelled extension study
Astrup, A., Madsbad, Sten, Breum, Leif, Kroustrup, J. P., Raben, A., Jensen, J. K. S., Meier, D. & Sjödin, Anders Mikael, 2009, In: Obesity Facts. suppl. 2, p. 211-212 2 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Under-reporting of adverse effects of tesofensine
Astrup, A., Madsbad, Sten, Breum, Leif, Jensen, T. J., Kroustrup, J. P. & Larsen, T. M., 2013, In: Lancet. 382, 9887, p. 127 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Tesofensine and weight loss - Authors' reply
Astrup, A., Madsbad, Sten & Larsen, T. M., 26 Feb 2009, In: Lancet. 373, 9665, p. 720 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Ny viden om årsag til diabetes: Type 2-diabetes œndres til »adipositas-dependent diabetes mellitus«
Astrup, A., Madsbad, Sten & Finer, N., 2001, In: Ugeskrift for læger. 163, 2, p. 141-143 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 10877
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Instrumentalization of eating improves weight loss maintenance in obesity
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Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB
Research output: Contribution to journal › Journal article › Research › peer-review
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Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota
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