Søren-Peter Olesen
Professor
Molecular Cardiology and Membrane Proteins
Blegdamsvej 3, 2200 København N.
- 1998
- Published
Characterization of the cloned human intermediate-conductance Ca*O2*O+-activated K*O+ channel
Jensen, B. S., Strøbæk, D., Christophersen, P., Jørgensen, T. D., Hansen, C., Silahtaroglu, Asli, Olesen, Søren-Peter & Ahring, P. K., 1998, In: The American Physiological Society. p. 848-856Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hydralazine-induced vasodilation involves opening of high conductan Ca2+-activated K+ channels
Bang, L., Nielsen-Kudsk, J. E., Gruhn, N., Trautner, S., Theilgaard, S. A., Olesen, Søren-Peter, Boesgaard, S. & Aldershvile, J., 1998, In: European Journal of Pharmacology. 361(1), p. 43-49Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Activation of the human intermediate-conductance Ca2+-activated K+ channel by 1-ethyl-2-benzimidazolinone is strongly Ca2+-dependent
Pedersen, K. A., Schrøder, R. L. K., Skanning-Jensen, B., Strøbæk, D., Olesen, Søren-Peter & Christophersen, P., 1999, In: BBA General Subjects. 77660, p. 01-10Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional characterization of a cloned human intermediate-conductance Ca2+-activated K+ channel
Jørgensen, T. D., Jensen, B. S., Strøbæk, D., Christofersen, P., Olesen, Søren-Peter & Ahring, B. K., 1999, In: Annals of the New York Academy of Sciences. 868, p. 423-426Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of T cell proliferation by selective block of Ca(2+)-activated K(+) channels
Jensen, B. S., Ødum, Niels, Jorgensen, N. K., Christophersen, P. & Olesen, Søren-Peter, 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, 19, p. 10917-21 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of T cell proliferation by selective block of Ca2+-activated K+ channels
Jensen, B. S., Ødum, Niels, Jørgensen, N. K., Christophersen, P. & Olesen, Søren-Peter, 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, p. 10917-10921Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vascular smooth muscle contraction is an independent regulator of endothelial nitric oxide production
Bang, L., Nielsen-Kudsk, J. E., Gruhn, N., Theilgaard, S. A., Olesen, Søren-Peter & Aldershvile, J., 1999, In: Scandinavian Cardiovascular Journal. 33, p. 71-78Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
Activation of the human, intermediate-conductance, Ca2+-activated K+ channel by methylxanthines
Schrøder, R. L. K., Jensen, B. S., Strøbaek, D., Olesen, Søren-Peter & Christophersen, P., 2000, In: Pflügers Archiv: European Journal of Physiology. 440, p. 809-818Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of the human intermediate-conductance, Ca2+-activated K+ channel by intracellular acidification
Pedersen, K. A., Jørgensen, N. K., Jensen, B. S. & Olesen, Søren-Peter, 2000, In: Pflügers Archiv: European Journal of Physiology. 440(1), p. 153-156Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological characterization of small-conductance Ca(2+)-activated channels stably expressed in HEK 293 cells
Strobaek, D., Jørgensen, T. D., Christophersen, P., Ahring, P. K. & Olesen, Søren-Peter, 2000, In: British Journal of Pharmacology. 129(5), p. 991-999Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
Apamin interacts with all subtypes of cloned small-conductance Ca2+-activated K+ channels
Grunnet, Morten, Jensen, B. S., Olesen, Søren-Peter & Klærke, Dan Arne, 2001, In: Pflügers Archiv: European Journal of Physiology. 441, p. 544-550Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a novel voltage-gated Na+ channel rNav 1.5a in the rat hippocampal progenitor stem cell line HiB5
Korsgaard, M., Grunnet, Morten, Christophersen, P., Ahring, P. K. & Olesen, Søren-Peter, 2001, In: Pflügers Archiv: European Journal of Physiology. 443, p. 18-30Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KCNQ4 channel activation by BMS204352 and retigabine
Schrøder, R. L., Strøbaek, D., Christophersen, P., Jensen Skanning, B. & Olesen, Søren-Peter, 2001, In: Neuropharmacology. 40, p. 888-898Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KCNQ4 channels expressed in mammalian cells: Functional characteristics and pharmacology
Søgaard, R., Ljungstrøm, T., Pedersen, K. A., Olesen, Søren-Peter & Jensen Skanning, B., 2001, In: American Journal of Physiology: Cell Physiology. 280, p. C859-C866Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Ca2+-activated K+ channel of intermediate-conductance: A molecular target for novel treatments?
Jensen Skanning, B., Strøbaek, D., Olesen, Søren-Peter & Christophersen, P., 2001, In: Current Drug Targets. 2, p. 401-422Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An ERG channel inhibitor from the scorpion Buthus eupeus
Korolkova, Y. V., Kozlov, S. A., Lipkin, A. V., Pluzhnikov, K. A., Hadley, J. K., Filippov, A. K., Brown, D. A., Pedersen, K. A., Strøbaek, D., Jespersen, Thomas, Olesen, Søren-Peter, Jensen Skanning, B. & Grishin, E. V., 30 Mar 2001, In: Journal of Biological Chemistry. 276, 13, p. 9868-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Activation of KCNQ5 channels stably expressed in HEK293 cells by BMS-204352.
Dupuis, D. S., Schrøder, R. L., Jespersen, Thomas, Christensen, J. K., Christophersen, P., Jensen, B. S. & Olesen, Søren-Peter, 2002, In: European Journal of Pharmacology. 437, 3, p. 129-37 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CNTF inhibits high voltage activated Ca2+ currents in fetal mouse cortical neurones.
Holm, N. R., Christophersen, P., Hounsgaard, Jørn Dybkjær, Gammeltoft, S. & Olesen, Søren-Peter, 2002, In: Journal of Neurochemistry. 82, 3, p. 495-503 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KCNE4 is an inhibitory subunit to the KCNQ1 channel.
Grunnet, Morten, Jespersen, Thomas, Rasmussen, Hanne Borger, Ljungstrøm, T., Jorgensen, N. K., Olesen, Søren-Peter & Klærke, Dan Arne, 2002, In: Journal of Physiology. 542, Pt 1, p. 119-30 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current.
Angelo, K., Jespersen, Thomas, Grunnet, Morten, Nielsen, Morten Schak, Klærke, Dan Arne & Olesen, Søren-Peter, 2002, In: Biophysical Journal. 83, 4, p. 1997-2006 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1.
Korolkova, Y. V., Bocharov, E. V., Angelo, K., Maslennikov, I. V., Grinenko, O. V., Lipkin, A. V., Nosyreva, E. D., Pluzhnikov, K. A., Olesen, Søren-Peter, Arseniev, A. S. & Grishin, E. V., 2002, In: Journal of Biological Chemistry. 277, 45, p. 43104-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of cloned, Ca2+-activated K+ channels by cell volume changes.
Grunnet, Morten, MacAulay, Nanna, Jorgensen, N. K., Jensen, S., Olesen, Søren-Peter & Klærke, Dan Arne, 2002, In: Pflügers Archiv: European Journal of Physiology. 444, 1-2, p. 167-77 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unique binding site on the molecular scaffold of scorpion toxin BeKm-1 provides selectivity for HERG potassium channels
Korolkova, Y. V., Bocharov, E. V., Pedersen, K. A., Maslennikov, I. V., Grinenko, O. V., Lipkin, A. V., Nosireva, E. D., Pluzhnikov, K. A., Olesen, Søren-Peter, Arseniev, A. S. & Grishin, E. V., 2002, In: Journal of Biological Chemistry. 277, p. 43104-43109Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
A radiolabeled peptide ligand of the hERG channel, [125I]-BeKm-1.
Angelo, K., Korolkova, Y. V., Grunnet, Morten, Grishin, E. V., Pluzhnikov, K. A., Klærke, Dan Arne, Knaus, H., Møller, Morten & Olesen, Søren-Peter, 2003, In: Pflügers Archiv: European Journal of Physiology. 447, 1, p. 55-63 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell swelling activates cloned Ca(2+)-activated K(+) channels: a role for the F-actin cytoskeleton.
Jorgensen, N. K., Pedersen, Stine Helene Falsig, Rasmussen, Hanne Borger, Grunnet, Morten, Klærke, Dan Arne & Olesen, Søren-Peter, 2003, In: BBA General Subjects. 1615, 1-2, p. 115-25 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of two new dominant ClC-1 channel mutations associated with myotonia.
Grunnet, Morten, Jespersen, Thomas, Colding-Jørgensen, E., Schwartz, M., Klærke, Dan Arne, Vissing, John, Olesen, Søren-Peter & Dunø, M., 2003, In: Muscle & Nerve. 28, 6, p. 722-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional coupling between heterologously expressed dopamine D(2) receptors and KCNQ channels.
Ljungstrom, T., Grunnet, Morten, Jensen, B. S. & Olesen, Søren-Peter, 2003, In: Pflügers Archiv: European Journal of Physiology. 446, 6, p. 684-94 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High throughput electrophysiology: new perspectives for ion channel drug discovery.
Willumsen, N. J., Bech, M., Olesen, Søren-Peter, Jensen, B. S., Korsgaard, M. P. G. & Christophersen, P., 2003, In: Receptors and Channels. 9, 1, p. 3-12 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.
Grunnet, Morten, Rasmussen, H. B., Hay-Schmidt, Anders, Rosenstierne, M., Klærke, Dan Arne, Olesen, Søren-Peter & Jespersen, Thomas, 2003, In: Biophysical Journal. 85, 3, p. 1525-37 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KCNQ1 channels sense small changes in cell volume.
Grunnet, Morten, Jespersen, Thomas, MacAulay, Nanna, Jørgensen, N. K., Schmitt, Nicole, Pongs, O., Olesen, Søren-Peter & Klærke, Dan Arne, 2003, In: Journal of Physiology. 549, Pt 2, p. 419-27 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological investigation of the role of ion channels in salivary secretion.
Stummann, T. C., Poulsen, J. H., Hay-Schmidt, Anders, Grunnet, Morten, Klærke, Dan Arne, Rasmussen, Hanne Borger, Olesen, Søren-Peter & Jorgensen, N. K., 2003, In: Pflügers Archiv: European Journal of Physiology. 446, 1, p. 78-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subcellular localization of the delayed rectifier K(+) channels KCNQ1 and ERG1 in the rat heart.
Rasmussen, Hanne Borger, Møller, Morten, Knaus, H., Jensen, B. S., Olesen, Søren-Peter & Jørgensen, N. K., 2003, In: American Journal of Physiology: Heart and Circulatory Physiology. 286, 4, p. H1300-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role og K+ and C1- channels in salivary secretion
Stummann, T. C., Poulsen, J. H., Hay-Schmidt, Anders, Grunnet, Morten, Klærke, Dan Arne, Olesen, Søren-Peter & Jørgensen, N. K., 2003, In: Pflügers Archiv: European Journal of Physiology. 446, p. 78-87Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Voltage-independent KCNQ4 currents induced by (+/-)BMS-204352.
Schrøder, R. L., Strøbaek, D., Olesen, Søren-Peter & Christophersen, P., 2003, In: Pflügers Archiv: European Journal of Physiology. 446, 5, p. 607-16 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime).
Strøbaek, D., Teuber, L., Jørgensen, T. D., Ahring, P. K., Kjaer, K., Hansen, R. S., Olesen, Søren-Peter, Christophersen, P. & Skaaning-Jensen, B., 2004, In: BBA General Subjects. 1665, 1-2, p. 1-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif.
Jespersen, Thomas, Rasmussen, Hanne Borger, Grunnet, Morten, Jensen, H. S., Angelo, K., Dupuis, D. S., Vogel, L. K., Jorgensen, N. K., Klærke, Dan Arne & Olesen, Søren-Peter, 2004, In: Journal of Cell Science. 117, Pt 19, p. 4517-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation of KCNQ4 channel activity by changes in cell volume.
Hougaard, C., Klærke, Dan Arne, Hoffmann, E. K., Olesen, Søren-Peter & Jorgensen, N. K., 2004, In: BBA General Subjects. 1660, 1-2, p. 1-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation of the KCNQ4 potassium channel by changes in cell volume
Hougaard, C., Klærke, Dan Arne, Olesen, Søren-Peter, Hoffmann, E. K. & Jørgensen, N. K., 2004, In: Acta Physiologica (Print Edition). A45-A163, p. A64-A65Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Subcellular localization of the delayed rectifier potassium channel KCNQ1 and ERG1 in rat heart
Rasmussen, H. B., Møller, M., Knaus, H. G., Jensen, B. S., Olesen, Søren-Peter & Jørgensen, N. K., 2004, In: American Journal of Physiology: Heart and Circulatory Physiology. 286, p. H1300-H1309Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643).
Hansen, R. S., Diness, T. G., Christ, T., Demnitz, J., Ravens, U., Olesen, Søren-Peter & Grunnet, Morten, 2005, In: Molecular Pharmacology. 69, 1, p. 266-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blockade of Ca2+-activated K+ channels in T cells: an option for the treatment of multiple sclerosis?
Madsen, L. S., Christophersen, P. & Olesen, Søren-Peter, 2005, In: European Journal of Immunology. 35, 4, p. 1023-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of beta-adrenoceptor blockers on human ether-a-go-go-related gene (HERG) potassium channels.
Dupuis, D. S., Klærke, Dan Arne & Olesen, Søren-Peter, 2005, In: Basic & Clinical Pharmacology & Toxicology. 96, 2, p. 123-30 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional assessment of compound mutations in the KCNQ1 and KCNH2 genes associated with long QT syndrome.
Grunnet, Morten, Behr, E. R., Callø, Kirstine, Hofman-Bang, J., Till, J., Christiansen, M., McKenna, W. J., Olesen, Søren-Peter & Schmitt, Nicole, 2005, In: Heart Rhythm. 2, 11, p. 1238-49 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels.
Callø, Kirstine, Elmedyb, P., Olesen, Søren-Peter, Jorgensen, N. K. & Grunnet, Morten, 2005, In: Biophysical Journal. 89, 3, p. 2159-69 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism of action of a novel human ether-a-go-go-related gene channel activator.
Casis, O., Olesen, Søren-Peter & Sanguinetti, M. C., 2005, In: Molecular Pharmacology. 69, 2, p. 658-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The KCNQ1 potassium channel: from gene to physiological function.
Jespersen, Thomas, Grunnet, Morten & Olesen, Søren-Peter, 2005, In: Physiology. 20, p. 408-16 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes.
Jensen, H. S., Callø, Kirstine, Jespersen, Thomas, Jensen, B. S. & Olesen, Søren-Peter, 2005, In: Brain Research. 139, 1, p. 52-62 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
hKCNE4 inhibits the hKCNQ1 potassium current without affecting the activation kinetics.
Grunnet, Morten, Olesen, Søren-Peter, Klærke, Dan Arne & Jespersen, Thomas, 2005, In: Biochemical and Biophysical Research Communications. 328, 4, p. 1146-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Activation of HERG potassium channels by the diphenylurea NS1643
Hansen, R. S., Diness, T. G., Christ, T., Demnitz, J., Ravens, U. & Olesen, Søren-Peter, 2006, In: Molecular Pharmacology. 69, p. 266-277Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biophysical characterization of the new human ether-a-go-go-related gene channel opener NS3623[N-(4-bromo-2-(1H-tetrazol-5-yl)-phenyl)-N '-(3 '-trifluoromethylphenyl)urea]
Hansen, R. S., Diness, T. G., Christ, T., Wettwer, E., Ravens, U., Olesen, Søren-Peter & Grunnet, Morten, 2006, In: Molecular Pharmacology. 70, 4, p. 1319-1329 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13436
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Tissue-specific effects of acetylcholine in the canine heart
Research output: Contribution to journal › Journal article › Research › peer-review
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492
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Non-invasive detection of animal nerve impulses with an atomic magnetometer operating near quantum limited sensitivity
Research output: Contribution to journal › Journal article › Research › peer-review
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340
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Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Research output: Contribution to journal › Journal article › Research › peer-review
Published