Signe Regner Michaelsen
Postdoc
Kristensen Group
Ole Maaløes Vej 5
2200 København N.
- 2012
- Published
Single agent- and combination treatment with two targeted suicide gene therapy systems is effective in chemoresistant small cell lung cancer cells
Michaelsen, Signe Regner, Christensen, C. L., Sehested, M., Cramer, F., Poulsen, T. T., Patterson, A. V. & Poulsen, H. S., 2012, In: Journal of Gene Medicine (Online). 14, 7, p. 445-58 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Clinical variables serve as prognostic factors in a model for survival from glioblastoma multiforme: an observational study of a cohort of consecutive non-selected patients from a single institution
Michaelsen, Signe Regner, Christensen, I. J., Grunnet, K., Stockhausen, M., Broholm, H., Kosteljanetz, M. & Poulsen, H. S., 2013, In: B M C Cancer. 13, p. 1-11 11 p., 402.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
The Use of Longitudinal 18F-FET MicroPET Imaging to Evaluate Response to Irinotecan in Orthotopic Human Glioblastoma Multiforme Xenografts
Nedergaard, M. K., Kristoffersen, K., Michaelsen, Signe Regner, Madsen, J., Poulsen, H. S., Stockhausen, M., Lassen, Ulrik Niels & Kjær, Andreas, 2014, In: PloS one. 9, 6, p. 1-10 10 p., e100009.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of bevacizumab treatment on survival and quality of life in newly diagnosed glioblastoma patients
Poulsen, H. S., Urup, T., Michaelsen, Signe Regner, Staberg, M., Villingshøj, M. & Lassen, Ulrik Niels, 2014, In: Cancer Management and Research. 6, p. 373-387 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor
Christensen, C. L., Kwiatkowski, N., Abraham, B. J., Carretero, J., Al-Shahrour, F., Zhang, T., Chipumuro, E., Herter-Sprie, G. S., Akbay, E. A., Altabef, A., Zhang, J., Shimamura, T., Capelletti, M., Reibel, J. B., Cavanaugh, J. D., Gao, P., Liu, Y., Michaelsen, S. R., Poulsen, H. S., Aref, A. R. & 6 others, , Dec 2014, In: Cancer Cell. 26, 6, p. 909-922 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
18F-FET microPET and microMRI for anti-VEGF and anti-PlGF response assessment in an orthotopic murine model of human glioblastoma
Nedergaard, M. K., Michaelsen, Signe Regner, Urup, T., Broholm, H., El Ali, Henrik H., Poulsen, H. S., Stockhausen, M., Kjær, Andreas & Lassen, Ulrik Niels, 2015, In: P L o S One. 10, 2, p. 1-16 16 p., e0115315.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Combined EGFR- and notch inhibition display additive inhibitory effect on glioblastoma cell viability and glioblastoma-induced endothelial cell sprouting in vitro
Staberg, M., Michaelsen, Signe Regner, Olsen, L. S., Nedergaard, M. K., Villingshøj, M., Stockhausen, M., Hamerlik, P. & Poulsen, H. S., 2016, In: Cancer Cell International. 16, 34.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development and validation of a prognostic model for recurrent glioblastoma patients treated with bevacizumab and irinotecan
Urup, T., Dahlrot, R. H., Grunnet, K., Christensen, I. J., Michaelsen, Signe Regner, Toft, A., Larsen, V. A., Broholm, H., Kosteljanetz, M., Hansen, S., Poulsen, H. S. & Lassen, Ulrik Niels, 2016, In: Acta Oncologica. 55, 4, p. 418-22 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urokinase-Type Plasminogen Activator Receptor as a Potential PET Biomarker in Glioblastoma
Persson, M., Nedergaard, M. K., Brandt-Larsen, M., Skovgaard, D., Jørgensen, Jesper Tranekjær, Michaelsen, Signe Regner, Madsen, J., Lassen, Ulrik Niels, Poulsen, H. S. & Kjær, Andreas, Feb 2016, In: Journal of Nuclear Medicine. 57, 2, p. 272-278 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessment of Quantitative and Allelic MGMT Methylation Patterns as a Prognostic Marker in Glioblastoma
Kristensen, L. S., Michaelsen, Signe Regner, Dyrbye, H., Aslan, D., Grunnet, K., Christensen, I. J., Poulsen, H. S., Grønbæk, Kirsten & Broholm, H., Mar 2016, In: Journal of Neuropathology and Experimental Neurology. 75, 3, p. 246-55 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of (18)F-FET and (18)F-FLT small animal PET for the assessment of anti-VEGF treatment response in an orthotopic model of glioblastoma
Nedergaard, M. K., Michaelsen, Signe Regner, Perryman, L., Erler, Janine, Poulsen, H. S., Stockhausen, M., Lassen, Ulrik Niels & Kjær, Andreas, Mar 2016, In: Nuclear Medicine and Biology. 43, 3, p. 198-205 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Angiotensinogen and HLA class II predict bevacizumab response in recurrent glioblastoma patients
Urup, T., Michaelsen, Signe Regner, Olsen, L. R., Toft, A., Christensen, I. J., Grunnet, K., Winther, Ole, Broholm, H., Kosteljanetz, M., Issazadeh-Navikas, Shohreh, Poulsen, H. S. & Lassen, Ulrik Niels, Oct 2016, In: Molecular Oncology. 10, 8, p. 1160-1168Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Transcriptional changes induced by bevacizumab combination therapy in responding and non-responding recurrent glioblastoma patients
Urup, T., Staunstrup, L. M., Michaelsen, Signe Regner, Vitting-Seerup, K., Bennedbæk, M., Toft, A., Olsen, L. R., Jønson, L., Issazadeh-Navikas, Shohreh, Broholm, H., Hamerlik, P., Poulsen, H. S. & Lassen, Ulrik Niels, 18 Apr 2017, In: BMC Cancer. 17, 10 p., 278.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Biomarkers in Recurrent Grade III Glioma Patients Treated with Bevacizumab and Irinotecan
Toft, A., Urup, T., Christensen, I. J., Michaelsen, Signe Regner, Lukram, B., Grunnet, K., Kosteljanetz, M., Larsen, V. A., Lassen, Ulrik Niels, Broholm, H. & Poulsen, H. S., 2018, In: Cancer Investigation. 36, 2, p. 165-174 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA methylation levels of the ELMO gene promoter CpG islands in human glioblastomas
Michaelsen, Signe Regner, Aslan, D., Urup, T., Poulsen, H. S., Grønbæk, Kirsten, Broholm, H. & Kristensen, L. S., 2018, In: International Journal of Molecular Sciences . 19, 3, 13 p., 679.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular profiling of short-term and long-term surviving patients identifies CD34 mRNA level as prognostic for glioblastoma survival
Michaelsen, Signe Regner, Urup, T., Olsen, L. R., Broholm, H., Lassen, Ulrik Niels & Poulsen, H. S., 2018, In: Journal of Neuro-Oncology. 137, 3, p. 533-542 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting glioma stem-like cell survival and chemoresistance through inhibition of lysine-specific histone demethylase KDM2B
Staberg, M., Rasmussen, R. D., Michaelsen, Signe Regner, Pedersen, H., Jensen, K. E., Villingshøj, M., Skjoth-Rasmussen, J., Brennum, J., Vitting-Seerup, K., Poulsen, H. S. & Hamerlik, P., 2018, In: Molecular Oncology. 12, 3, p. 406-420 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
VEGF-C sustains VEGFR2 activation under bevacizumab therapy and promotes glioblastoma maintenance
Michaelsen, Signe Regner, Staberg, M., Pedersen, H., Jensen, K. E., Majewski, W., Broholm, H., Nedergaard, M. K., Meulengracht, C., Urup, T., Villingshøj, M., Lukacova, S., Skjøth-Rasmussen, J., Brennum, J., Kjær, Andreas, Lassen, Ulrik Niels, Stockhausen, M., Poulsen, H. S. & Hamerlik, P., 2018, In: Neuro-Oncology. 20, 11, p. 1462-1474Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Angiotensinogen promoter methylation to predict bevacizumab response in recurrent glioblastoma patients
Urup, T., Gillberg, Linn, Kaastrup, K., Lu, M. S., Michaelsen, Signe Regner, Larsen, V. A., Christensen, I. J., Broholm, H., Lassen, Ulrik Niels, Grønbæk, Kirsten & Poulsen, H. S., 2019, In: Neuro-Oncology. 21, Supplement 6, p. vi149Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Cell-free DNA in newly diagnosed patients with glioblastoma - a clinical prospective feasibility study
Nørøxe, D. S., Østrup, O., Yde, C. W., Ahlborn, L. B., Nielsen, Finn Cilius, Michaelsen, Signe Regner, Larsen, V. A., Skjøth-Rasmussen, J., Brennum, J., Hamerlik, P., Poulsen, H. S. & Lassen, Ulrik Niels, 2019, In: OncoTarget. 10, 43, p. 4397-4406 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical Characteristics of Gliosarcoma and Outcomes From Standardized Treatment Relative to Conventional Glioblastoma
Frandsen, S., Broholm, H., Larsen, V. A., Grunnet, K., Moller, S., Poulsen, H. S. & Michaelsen, Signe Regner, 2019, In: Frontiers in Oncology. 9, p. 1-11 01425.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extracranial metastases in glioblastoma—Two case stories
Schou Nørøxe, D., Michaelsen, Signe Regner, Broholm, H., Møller, Søren, Skovgaard Poulsen, H. & Lassen, Ulrik Niels, 2019, In: Clinical Case Reports. 7, 2, p. 289-294 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
VEGF-C as a putative therapeutic target in cancer
Michaelsen, Signe Regner, Poulsen, H. S. & Hamerlik, P., 18 Jun 2019, In: OncoTarget. 10, 40, p. 3988-3990 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- 2020
- Published
Angiotensinogen promoter methylation predicts bevacizumab treatment response of patients with recurrent glioblastoma
Urup, T., Gillberg, Linn, Kaastrup, K., Lü, M. J. S., Michaelsen, Signe Regner, Andrée Larsen, V., Christensen, I. J., Broholm, H., Lassen, Ulrik Niels, Grønbæk, Kirsten & Poulsen, H. S., 2020, In: Molecular Oncology. 14, 5, p. 964-973Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic profiling of newly diagnosed glioblastoma patients and its potential for clinical utility – a prospective, translational study
Nørøxe, D. S., Yde, C. W., Østrup, O., Michaelsen, Signe Regner, Schmidt, A. Y., Kinalis, S., Torp, M. H., Skjøth‐Rasmussen, J., Brennum, J., Hamerlik, P., Poulsen, H. S., Nielsen, Finn Cilius & Lassen, Ulrik Niels, 2020, In: Molecular Oncology.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
A Prognostic Model for Glioblastoma Patients Treated With Standard Therapy Based on a Prospective Cohort of Consecutive Non-Selected Patients From a Single Institution
Abedi, A. A., Grunnet, K., Christensen, I. J., Michaelsen, Signe Regner, Muhic, A., Møller, Søren, Hasselbalch, B., Poulsen, H. S. & Urup, T., 2021, In: Frontiers in Oncology. 11, 597587.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug Repurposing Screen Reveals Glioblastoma Cell Line Susceptibility to Statins
Harwood, Dylan Scott Lykke, Michaelsen, Signe Regner, Mundt, F. & Kristensen, Bjarne Winther, 2021, In: Neuro-Oncology. 23, S6, p. 77-78 2 p.Research output: Contribution to journal › Conference abstract in journal › Research
- 2022
- Published
Surgical resection of glioblastomas induces pleiotrophin-mediated self-renewal of glioblastoma stem cells in recurrent tumors
Knudsen, A. M., Halle, B., Cédile, O., Burton, M., Baun, C., Thisgaard, H., Anand, Atul, Hubert, C., Thomassen, M., Michaelsen, Signe Regner, Olsen, B. B., Dahlrot, R. H., Bjerkvig, R., Lathia, J. D. & Kristensen, Bjarne Winther, 2022, In: Neuro-Oncology. 24, 7, p. 1074-1087 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Differential expression of checkpoint markers in the normoxic and hypoxic microenvironment of glioblastomas
Petterson, S. A., Sørensen, M. D., Burton, M., Thomassen, M., Kruse, T. A., Michaelsen, Signe Regner & Kristensen, Bjarne Winther, 2023, In: Brain Pathology. 33, 1, 14 p., e13111.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of cancer cell-derived ADAM15 alters the tumor microenvironment in colorectal tumors
Puig Blasco, Laia, Piotrowski, Kris, Michaelsen, Signe Regner, Bager, Nicolai Stilling Schou, Areškevičiūtiė, A., Thorseth, M., Sun, X., Keller, U. A. D., Kristensen, Bjarne Winther, Madsen, D. H., Gnosa, S. P. & Kveiborg, Marie, 2023, In: International Journal of Cancer. 153, 12, p. 2068–2081 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 108812376
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Angiotensinogen and HLA class II predict bevacizumab response in recurrent glioblastoma patients
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
114
downloads
Transcriptional changes induced by bevacizumab combination therapy in responding and non-responding recurrent glioblastoma patients
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
102
downloads
Targeting glioma stem-like cell survival and chemoresistance through inhibition of lysine-specific histone demethylase KDM2B
Research output: Contribution to journal › Journal article › Research › peer-review
Published