Sara Marie Øie Solbak

Sara Marie Øie Solbak

Assistant Professor

ORCID: 0000-0003-0233-7160

Publication year:
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1 - 23 out of 23Page size: 50
  1. 2023
  2. Published

    Co-adjuvanting DDA/TDB liposomes with a TLR7 agonist allows for IgG2a/c class-switching in the absence of Th1 cells

    Zimmermann, J., van Haren, S. D., Arce, J., Adriawan, I. R., Wørzner, K., Krog, R. T., Guleed, S., Hu, T., Mortensen, R., Dietrich, J., Solbak, Sara Marie Øie, Levy, O., Christensen, D. & Pedersen, Gabriel Kristian, 2023, In: npj Vaccines. 8, 1, 12 p., 189.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2022
  4. Published

    Discovery and Optimization of 5-Hydroxy-Diclofenac toward a New Class of Ligands with Nanomolar Affinity for the CaMKIIα Hub Domain

    Tian, Yongsong, Shehata, M. A., Gauger, Stine Juul, Ng, C. K. L., Solbak, Sara Marie Øie, Thiesen, L., Bruus-Jensen, J., Krall, J., Bundgaard, C., Gibson, K. M., Wellendorph, Petrine & Frølund, Bente, 2022, In: Journal of Medicinal Chemistry. 65, 9, p. 6656-6676

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Exploring the NCS-382 Scaffold for CaMKII alpha Modulation: Synthesis, Biochemical Pharmacology, and Biophysical Characterization of Ph-HTBA as a Novel High-Affinity Brain-Penetrant Stabilizer of the CaMKII alpha Hub Domain

    Tian, Yongsong, Shehata, M. A., Gauger, Stine Juul, Veronesi, C., Hamborg, L., Thiesen, L., Bruus-Jensen, J., Royssen, J. S., Leurs, U., Larsen, A. S. G., Krall, J., Solbak, Sara Marie Øie, Wellendorph, Petrine & Frølund, Bente, 2022, In: Journal of Medicinal Chemistry. 65, 22, p. 15066–15084

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2021
  7. Published

    Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds

    Pallesen, J. S., Narayanan, Dilip, Tran, K. T., Solbak, Sara Marie Øie, Marseglia, G., Sørensen, L. M. E., Høj, L. J., Munafò, F., Carmona, R. M. C., Garcia, A. D., Desu, H. L., Brambilla, R., Johansen, Tommy Nørskov, Popowicz, G. M., Sattler, M., Gajhede, Michael & Bach, Anders, 2021, In: Journal of Medicinal Chemistry. 64, 8, p. 4623–4661

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

    Leurs, U., Klein, A. B., McSpadden, E. D., Griem-Krey, N., Solbak, S. M. Ø., Houlton, J., Villumsen, I. S., Vogensen, S. B., Hamborg, L., Gauger, S. J., Palmelund, L. B., Larsen, A. S. G., Shehata, M. A., Kelstrup, C. D., Olsen, J. V., Bach, A., Burnie, R. O., Kerr, D. S., Gowing, E. K., Teurlings, S. M. W. & 9 others, Chi, C. C., Gee, C. L., Frølund, Bente, Kornum, Birgitte Rahbek, van Woerden, G. M., Clausen, Rasmus Prætorius, Kuriyan, J., Clarkson, A. N. & Wellendorph, Petrine, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 31, 9 p., e2108079118.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Identification of novel fragments binding to the PDZ1-2 domain of PSD-95

    Zang, J., Ye, F., Solbak, Sara Marie Øie, Høj, L. J., Zhang, M. & Bach, Anders, 2021, In: ChemMedChem. 16, 6, p. 949-954

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2020
  11. Published

    The dynamics of linear polyubiquitin

    Jussupow, A., Messias, A. C., Stehle, R., Geerlof, A., Solbak, Sara Marie Øie, Paissoni, C., Bach, Anders, Sattler, M. & Camilloni, C., Oct 2020, In: Science Advances. 6, 42, 13 p., eabc3786.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Fibrin fragment E potentiates TGF-beta-induced myofibroblast activation and recruitment

    Fuchs, P. O., Calitz, C., Pavlovic, N., Binet, F., Solbak, Sara Marie Øie, Danielson, U. H., Kreuger, J., Heindryckx, F. & Gerwins, P., Aug 2020, In: Cellular Signalling. 72, 12 p., 109661.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery

    Solbak, Sara Marie Øie, Zang, J., Narayanan, Dilip, Høj, L. J., Bucciarelli, S., Softley, C., Meier, S., Langkilde, Annette Eva, Gotfredsen, C. H., Sattler, M. & Bach, Anders, 2020, In: Journal of Medicinal Chemistry. 63, 3, p. 1156-1177

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2019
  15. Published

    A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity

    Tran, K. T., Pallesen, J. S., Solbak, Sara Marie Øie, Narayanan, Dilip, Baig, A., Zang, J., Aguayo-Orozco, A., Carmona, R., Garcia, A. & Bach, Anders, 2019, In: Journal of Medicinal Chemistry. 62, 17, p. 8028-8052

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Molecular architecture of the Jumonji C family histone demethylase KDM5B

    Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, Osman Asghar, Lousen, R., Bucciarelli, S., Mehta, V., Sellés Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, P. A., Montoya, Guillermo, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Boesen, T. & Gajhede, Michael, 2019, In: Scientific Reports. 9, 13 p., 4019.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2017

  18. Characterization of interactions between hepatitis C virus NS5B polymerase, annexin A2 and RNA - effects on NS5B catalysis and allosteric inhibition.

    Solbak, Sara Marie Øie, Abdurakhmanov, E., Vedeler, A. & Danielson, U., Dec 2017, In: Virology Journal.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Insights from engineering the Affibody-Fc interaction with a computational-experimental method.

    Nosrati, M., Solbak, Sara Marie Øie, Nordesjö, O., Nissbeck, M., Dourado, D., Andersson, K., Housaindokht, M., Löfblom, J., Virtanen, A., Danielson, U. & Flores, S., Sep 2017, In: Protein engineering, design & selection : PEDS.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Biophysical Mode-of-Action and Selectivity Analysis of Allosteric Inhibitors of Hepatitis C Virus (HCV) Polymerase.

    Abdurakhmanov, E., Solbak, Sara Marie Øie & Danielson, U., Jun 2017, In: Viruses.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. 2014

  22. Mutation of the highly conserved Ser-40 of the HIV-1 p6 gag protein to Phe causes the formation of a hydrophobic patch, enhances membrane association, and polyubiquitination of Gag.

    Hahn, F., Setz, C., Friedrich, M., Rauch, P., Solbak, Sara Marie Øie, Frøystein, N., Henklein, P., Votteler, J., Fossen, T. & Schubert, U., Oct 2014, In: Viruses.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Serum IgG titres, but not avidity, correlates with neutralizing antibody response after H5N1 vaccination.

    Pedersen, G., Höschler, K., Solbak, Sara Marie Øie, Bredholt, G., Pathirana, R., Afsar, A., Breakwell, L., Nøstbakken, J., Raae, A., Brokstad, K., Sjursen, H., Zambon, M. & Cox, R., Jul 2014, In: Vaccine.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2013

  25. HIV-1 p6 - a structured to flexible multifunctional membrane-interacting protein.

    Solbak, Sara Marie Øie, Reksten, T., Hahn, F., Wray, V., Henklein, P., Henklein, P., Halskau, Ø., Schubert, U. & Fossen, T., Feb 2013, In: Biochimica et biophysica acta.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Influenza A virus protein PB1-F2 from different strains shows distinct structural signatures.

    Solbak, Sara Marie Øie, Sharma, A., Bruns, K., Röder, R., Mitzner, D., Hahn, F., Niebert, R., Vedeler, A., Henklein, P., Henklein, P., Schubert, U., Wray, V. & Fossen, T., Feb 2013, In: Biochimica et biophysica acta.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2012

  28. Nuclear import of isoforms of the cytomegalovirus kinase pUL97 is mediated by differential activity of NLS1 and NLS2 both acting through classical importin-α binding.

    Webel, R., Solbak, Sara Marie Øie, Held, C., Milbradt, J., Groß, A., Eichler, J., Wittenberg, T., Jardin, C., Sticht, H., Fossen, T. & Marschall, M., Aug 2012, In: The Journal of general virology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. HIV-1 p6-Another viral interaction partner to the host cellular protein cyclophilin A.

    Solbak, Sara Marie Øie, Reksten, T., Röder, R., Wray, V., Horvli, O., Raae, A., Henklein, P., Henklein, P. & Fossen, T., Apr 2012, In: Biochimica et biophysica acta.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2011

  31. Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly.

    Votteler, J., Neumann, L., Hahn, S., Hahn, F., Rauch, P., Schmidt, K., Studtrucker, N., Solbak, Sara Marie Øie, Fossen, T., Henklein, P., Ott, D., Holland, G., Bannert, N. & Schubert, U., 2011, In: Retrovirology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. The host-pathogen interaction of human cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains.

    Solbak, Sara Marie Øie, Wray, V., Horvli, O., Raae, A., Flydal, M., Henklein, P., Henklein, P., Nimtz, M., Schubert, U. & Fossen, T., 2011, In: BMC Structural Biology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 2010

  34. The intriguing cyclophilin A-HIV-1 Vpr interaction: prolyl cis/trans isomerisation catalysis and specific binding.

    Solbak, Sara Marie Øie, Reksten, T., Wray, V., Bruns, K., Horvli, O., Raae, A., Henklein, P., Henklein, P., Röder, R., Mitzner, D., Schubert, U. & Fossen, T., 2010, In: BMC Structural Biology.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 157688952