Petrine Wellendorph

Petrine Wellendorph

Professor

ORCID: 0000-0002-5455-8013

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  1. Published

    (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent gamma-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction

    Pan, Y., Gerasimov, M. R., Kvist, T., Wellendorph, Petrine, Madsen, K. K., Pera, E., Lee, H., Schousboe, Arne, Chebib, M., Bräuner, Hans, Craft, C. M., Brodie, J. D., Schiffer, W. K., Dewey, S. L., Miller, S. R. & Silverman, R. B., 1 Jan 2012, In: Journal of Medicinal Chemistry. 55, 1, p. 357-366

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    3-Hydroxy-2'-methoxy-6-methylflavone: a potent anxiolytic with a unique selectivity profile at GABA(A) receptor subtypes

    Karim, N., Gavande, N., Wellendorph, Petrine, Johnston, G. A. R., Hanrahan, J. R. & Chebib, M., 15 Dec 2011, In: Biochemical Pharmacology. 82, 12, p. 1971-1983

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A CLASS OF SMALL-MOLECULE COMPOUNDS AND THEIR PRODRUGS FOR INTERVENTION WITH CAMK2A, AND THEIR USE IN ACUTE BRAIN INJURIES AND CENTRAL HYPERSOMNIAS

    Frølund, Bente, Wellendorph, Petrine & Kornum, Birgitte Rahbek, 2020, Patent No. WO2020151795, 30 Jul 2020, Priority date 21 Jan 2019, Priority No. DK2019PA70040 20190121

    Research output: Patent

  4. Published

    A sequential high-yielding large-scale solution-method for synthesis of philanthotoxin analogues

    Wellendorph, Petrine, Jaroszewski, J. W., Hansen, S. H. & Franzyk, Henrik, 2003, In: European Journal of Medicinal Chemistry. 38, 1, p. 117-22 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Activity of L-alpha-amino acids at the promiscuous goldfish odorant receptor 5.24

    Christiansen, B., Wellendorph, Petrine & Bräuner, Hans, 24 Apr 2006, In: European Journal of Pharmacology. 536, 1-2, p. 98-101

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling

    Andersen, Jens Velde, Schousboe, Arne & Wellendorph, Petrine, 2023, In: Essays in Biochemistry. 67, 1, p. 77-91

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Astrocytic GABA Transporters: Pharmacological Properties and Targets for Antiepileptic Drugs

    Schousboe, Arne, Wellendorph, Petrine, Frølund, Bente, Clausen, Rasmus Prætorius & Krogsgaard-Larsen, Povl, 2017, Glial Amino Acid Transporters. Springer, Vol. 16. p. 283-296 14 p. (Advances in Neurobiology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  8. Published

    Autoradiographic imaging and quantification of the high-affinity GHB binding sites in rodent brain using (3)H-HOCPCA

    Klein, A. B., Bay, T., Villumsen, I. S., Falk-Petersen, C. B., Marek, A., Frølund, Bente, Clausen, Rasmus Prætorius, Hansen, H. D., Knudsen, Gitte Moos & Wellendorph, Petrine, Nov 2016, In: Neurochemistry International. 100, p. 138-145 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Autoradiography as a Simple and Powerful Method for Visualization and Characterization of Pharmacological Targets

    Griem-Krey, Nane, Klein, A. B., Herth, Matthias Manfred & Wellendorph, Petrine, 12 Mar 2019, In: Journal of visualized experiments : JoVE. 145, 11 p., e58879.

    Research output: Contribution to journal › Journal article › Communication

  10. Published

    Boganmeldelse: Bogsalonen Kubulus Alumni

    Wellendorph, Petrine, 2012

    Research output: Other contribution › Net publication - Internet publication › Communication

  11. Published

    CaMK2 modulators and their use in medicine

    Frølund, Bente, Shehata, M. A., Wellendorph, Petrine, Gauger, Stine Juul, Kuriyan, J., McSpadden, E. D., Poulsen, Lasse Brokmose, Fougiaxis, V. & Daraj, K., 2023, IPC No. A61K31/4164, A61K31/4178, A61P25/00, C07D277/06, C07D277/12, C07D277/56, C07D417/04, C07D417/10, Patent No. WO2023170024A1, 1 Jan 1970, Priority No. US202263318852P

    Research output: Patent

  12. Published

    CaMKIIα as a Promising Drug Target for Ischemic Grey Matter

    Griem-Krey, Nane, Clarkson, A. N. & Wellendorph, Petrine, 2022, In: Brain Sciences. 12, 12, 21 p., 1639.

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    Characterization of GPRC6A: a 7TM receptor activated by L-alpha-amino acids and positively modulated by divalent cations

    Wellendorph, Petrine, Hansen, K. B., Christiansen, B., Burhenne, N., Balsgaard, A., Greenwood, J. R., Walter, B., Schmale, H., Egebjerg, J. & Bräuner, Hans, 2008, In: Fundamental and Clinical Pharmacology. Suppl. 2, p. 19

    Research output: Contribution to journal › Conference abstract in journal › Research

  14. Published

    Chemogenomic discovery of allosteric antagonists at the GPRC6A receptor

    Gloriam, David E., Wellendorph, Petrine, Johansen, L. D., Thomsen, A. R. B., Phonekeo, K., Pedersen, D. S. & Bräuner, Hans, 23 Nov 2011, In: Chemistry & Biology. 18, 11, p. 1489-1498

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Compounds for the treatment of acute brain injury

    Klein, A. B., Leurs, U., Houlton, J., Clausen, Rasmus Prætorius, Frølund, Bente, Clarkson, A. & Wellendorph, Petrine, 2020, Patent No. CN111989094, 24 Nov 2020, Priority date 1 Feb 2019, Priority No. PCT/DK2019/050041

    Research output: Patent

  16. Published

    Cyanohydrin glycosides of Passiflora: distribution pattern, a saturated cyclopentane derivative from P. guatemalensis, and formation of pseudocyanogenic alpha-hydroxyamides as isolation artefacts

    Jaroszewski, J. W., Olafsdottir, E. S., Wellendorph, Petrine, Christensen, J. L., Franzyk, Henrik, Somanadhan, B., Budnik, B. A., Jørgensen, L. B. & Clausen, V., 2002, In: Phytochemistry. 59, 5, p. 501-11 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Accepted/In press

    Deletion of CaMKIIα disrupts glucose metabolism, glutamate uptake, and synaptic energetics in the cerebral cortex

    Andersen, Jens Velde, Westi, Emil Winther, Griem-Krey, Nane, Skotte, Niels Henning, Schousboe, Arne, Aldana, Blanca & Wellendorph, Petrine, 2023, (Accepted/In press) In: Journal of Neurochemistry.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Delineation of the GPRC6A Receptor Signaling Pathways Using a Mammalian Cell Line Stably Expressing the Receptor

    Jacobsen, S. E., Nørskov-Lauritsen, L., Thomsen, A. R. B., Smajilovic, S., Wellendorph, Petrine, Larsson, N. H. P., Lehmann, A., Bhatia, V. K. & Bräuner, Hans, Nov 2013, In: Journal of Pharmacology and Experimental Therapeutics. 347, 2, p. 298-309 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Demonstration of the dynamic mass redistribution label-free technology as a useful cell-based pharmacological assay for endogenously expressed GABAA receptors

    Klein, A. B., Nittegaard-Nielsen, M., Christensen, J. T., Al-Khawaja, A. & Wellendorph, Petrine, 19 Nov 2015, In: MedChemComm. 7, p. 426-432 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids

    Wellendorph, Petrine, Hansen, K. B., Balsgaard, A., Greenwood, J. R., Egebjerg, J. & Bräuner, Hans, Mar 2005, In: Molecular Pharmacology. 67, 3, p. 589-97

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Design, synthesis, and in vitro pharmacology of new radiolabeled ¿-hydroxybutyric acid analogues including photolabile analogues with irreversible binding to the high-affinity ¿-hydroxybutyric acid binding sites

    Sabbatini, P., Wellendorph, Petrine, Høg, S., Pedersen, M. H. F., Bräuner, Hans, Martiny, L., Frølund, Bente & Clausen, Rasmus Prætorius, 2010, In: Journal of Medicinal Chemistry. 53, 17, p. 6506-6510

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties

    Jensen, Anders A., Plath, N., Pedersen, M. H. F., Isberg, V., Krall, J., Wellendorph, Petrine, Stensbøl, T. B., Gloriam, David E., Krogsgaard-Larsen, Povl & Frølund, Bente, 14 Feb 2013, In: Journal of Medicinal Chemistry. 56, 3, p. 1211-27 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Development of a Robust Mammalian Cell-based Assay for Studying Recombinant α4 β1/3 δ GABAA Receptor Subtypes

    Falk-Petersen, C. B., Søgaard, R., Madsen, Kenneth Lindegaard, Klein, A. B., Frølund, Bente & Wellendorph, Petrine, Aug 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 2, p. 119-129 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Development of a medium throughput whole-cell microtiter plate Thr286 autophosphorylation assay for CaMKIIα using ELISA

    Palmelund, L. B., van Woerden, G. M., Bräuner, Hans & Wellendorph, Petrine, 2022, In: Journal of Pharmacological and Toxicological Methods. 118, 8 p., 107226.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Discovery and Optimization of 5-Hydroxy-Diclofenac toward a New Class of Ligands with Nanomolar Affinity for the CaMKIIα Hub Domain

    Tian, Yongsong, Shehata, M. A., Gauger, Stine Juul, Ng, C. K. L., Solbak, Sara Marie Øie, Thiesen, L., Bruus-Jensen, J., Krall, J., Bundgaard, C., Gibson, K. M., Wellendorph, Petrine & Frølund, Bente, 2022, In: Journal of Medicinal Chemistry. 65, 9, p. 6656-6676

    Research output: Contribution to journal › Journal article › Research › peer-review

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