Olaf Nielsen

Olaf Nielsen

Professor

ORCID: 0000-0001-7440-5201

Publication year:
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1 - 50 out of 88Page size: 50
  1. 2024
  2. Published

    Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs

    Olsen, Johan Gotthardt, Prestel, Andreas, Kassem, N., Broendum, S. S., Hossain, Mohammad Shamim, Simonsen, Signe, Grysbæk, M., Mortensen, J., Rytkjær, L. L., Haxholm, G. W., Marabini, R., Holmberg, Christian, Carr, A. M., Crehuet, R., Nielsen, Olaf & Kragelund, Birthe Brandt, 2024, In: Nucleic acids symposium series. 52, 4, p. 2030–2044 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    Revised fission yeast gene and allele nomenclature guidelines for machine readability

    Lera-ramírez, M., Bähler, J., Mata, J., Rutherford, K., Hoffman, C. S., Lambert, S., Oliferenko, S., Martin, S. G., Gould, K. L., Du, L., Sabatinos, S. A., Forsburg, S. L., Nielsen, Olaf, Nurse, P. & Wood, V., 2023, In: Genetics. 225, 3, 10 p., iyad143.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Temporal phosphoproteomics reveals WEE1-dependent control of 53BP1 pathway

    Petrosius, V., Benada, Jan, Nielsen, Olaf, Schoof, E. M. & Sørensen, Claus Storgaard, 2023, In: iScience. 26, 1, 24 p., 105806.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2022
  7. Published

    A context-dependent and disordered ubiquitin-binding motif

    Dreier, Jesper Elmsted, Prestel, Andreas, Martins, J. M., Brøndum, S. S., Nielsen, Olaf, Garbers, Anna Engstrøm, Suga, H., Boomsma, Wouter, Rogers, Joseph Matthew, Hartmann-Petersen, Rasmus & Kragelund, Birthe Brandt, 2022, In: Cellular and molecular life sciences : CMLS. 79, 9, 21 p., 484.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2019
  9. Published

    Comprehensive profiling of the fission yeast transcription start site activity during stress and media response

    Thodberg, Malte, Thieffry, A., Lange, Jette Bornholdt, Boyd, M., Holmberg, Christian, Azad, A., Workman, C. T., Chen, Y., Ekwall, K., Nielsen, Olaf & Sandelin, Albin Gustav, 28 Feb 2019, In: Nucleic Acids Research. 47, 4, p. 1671-1691 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The PCNA interaction motifs revisited: thinking outside the PIP-box

    Prestel, Andreas, Wichmann, N., Martins, J. M., Marabini, R., Kassem, N., Broendum, S. S., Otterlei, M., Nielsen, Olaf, Willemoës, Martin, Ploug, Michael, Boomsma, Wouter & Kragelund, Birthe Brandt, 2019, In: Cellular and Molecular Life Sciences. 76, 24, p. 4923-4943

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2018
  12. Published

    Functional and Expression Analyses of the Pneumocystis MAT Genes Suggest Obligate Sexuality through Primary Homothallism within Host Lungs

    Richard, S., Almeida, J. M. G. C. F., Cissé, O. H., Luraschi, A., Nielsen, Olaf, Pagni, M. & Hauser, P. M., 2018, In: mBio. 9, 1, 10 p., e02201-17.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2017
  14. Published

    Analysis of RNA metabolism in fission yeast

    Wise, J. A. & Nielsen, Olaf, May 2017, In: Cold Spring Harbor Protocols. 2017, 5, p. 365-372 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Deoxynucleoside salvage in fission yeast allows rescue of ribonucleotide reductase deficiency but not Spd1-mediated inhibition of replication

    Fleck, O., Fahnøe, Ulrik, Løvschal, K. V., Gasasira, M. U., Marinova, I. N., Kragelund, Birthe Brandt, Carr, A. M., Hartsuiker, E., Holmberg, Christian & Nielsen, Olaf, 25 Apr 2017, In: Genes. 8, 5, 14 p., 128.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2016
  17. Published

    Regulating retrotransposon activity through the use of alternative transcription start sites

    Persson, J., Steglich, B., Smialowska, A., Boyd, M., Lange, Jette Bornholdt, Andersson, Robin, Schurra, C., Arcangioli, B., Sandelin, Albin Gustav, Nielsen, Olaf & Ekwall, K., 2016, In: E M B O Reports. 17, 5, p. 753-768 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Synchronization of S phase in Schizosaccharomyces pombe cells by transient exposure to M-factor pheromone

    Nielsen, Olaf, 2016, In: Cold Spring Harbor Protocols. 2016, 9, p. 768-772 5 p.

    Research output: Contribution to journal › Journal article › Research

  19. 2015
  20. Published

    An IPTG-inducible derivative of the fission yeast nmt promoter

    Kjærulff, S. & Nielsen, Olaf, 2015, In: Yeast. 32, p. 469-478 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Single site suppressors of a fission yeast temperature-sensitive mutant in cdc48 identified by whole genome sequencing

    Marinova, I. N., Engelbrecht, J., Ewald, A., Langholm, L. L., Holmberg, Christian, Kragelund, Birthe Brandt, Gordon, C., Nielsen, Olaf & Hartmann-Petersen, Rasmus, 2015, In: P L o S One. 10, 2, 15 p., e0117779.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2014
  23. Published

    C/EBPα is dispensable for the ontogeny of PD-1+ CD4+ memory T cells but restricts their expansion in an age-dependent manner

    Norrie, I. C., Ohlsson, E., Nielsen, Olaf, Hasemann, M. S. & Porse, Bo Torben, 2014, In: P L o S One. 9, 1, p. 1-9 9 p., e84728.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Spd2 assists Spd1 in the modulation of ribonucleotide reductase architecture but does not regulate deoxynucleotide pools

    Vejrup-Hansen, R., Fleck, O., Landvad, K., Fahnøe, Ulrik, Broendum, S. S., Schreurs, A., Kragelund, Birthe Brandt, Carr, A. M., Holmberg, Christian & Nielsen, Olaf, 2014, In: Journal of Cell Science. 127, p. 2460-2470 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2013
  26. Published

    Spd1 accumulation causes genome instability independently of ribonucleotide reductase activity but functions to protect the genome when deoxynucleotide pools are elevated

    Fleck, O., Vejrup-Hansen, R., Watson, A., Carr, A. M., Nielsen, Olaf & Holmberg, Christian, 2013, In: Journal of Cell Science. 126, p. 4985-4994 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2012
  28. Published

    Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption

    Beck, H., Nähse-Kumpf, V., Larsen, Marie Sofie Yoo, O'Hanlon, K. A., Patzke, S., Holmberg, Christian, Mejlvang, J., Groth, Anja, Nielsen, Olaf, Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2012, In: Molecular and Cellular Biology. 32, 20, p. 4226-4236 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Replication: DNA Building Block Synthesis On Demand

    Holmberg, Christian & Nielsen, Olaf, 2012, In: Current Biology. 22, 8, p. R271-R272 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2011
  31. Published

    Schizosaccharomyces pombe Mms1 channels repair of perturbed replication into Rhp51 independent homologous recombination

    Vejrup-Hansen, R., Mizuno, K., Miyabe, I., Fleck, O., Holmberg, Christian, Murray, J. M., Carr, A. M. & Nielsen, Olaf, 2011, In: DNA Repair. 10, 3, p. 283-95 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2010
  33. Published

    Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast

    Moss, J., Tinline-Purvis, H., Walker, C. A., Folkes, L. K., Stratford, M. R., Hayles, J., Hoe, K., Kim, D., Park, H., Kearsey, S. E., Fleck, O., Holmberg, Christian, Nielsen, Olaf & Humphrey, T. C., 1 Dec 2010, In: Genes & Development. 24, 23, p. 2705-16 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms

    Nestoras, K., Mohammed, A. H., Schreurs, A., Fleck, O., Watson, A. T., Poitelea, M., O'Shea, Charlotte, Chahwan, C., Holmberg, Christian, Kragelund, Birthe Brandt, Nielsen, Olaf, Osborne, M., Carr, A. M. & Liu, C., 1 Jun 2010, In: Genes & Development. 24, 11, p. 1145-1159 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. 2008
  36. Published

    Once in a lifetime: strategies for preventing re-replication in prokaryotic and eukaryotic cells.

    Nielsen, Olaf & Løbner-Olesen, Anders, 2008, In: EMBO Reports. 9, 2, p. 151-156 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  37. 2007
  38. Published

    Cdk phosphorylation of the Ste11 transcription factor constrains differentiation-specific transcription to G1.

    Kjaerulff, S., Andersen, N. R., Borup, M. T. & Nielsen, Olaf, 2007, In: Genes & Development. 21, 3, p. 347-59 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Fission yeast goes synthetic.

    Nielsen, Olaf, 2007, In: Nature Methods. 4, 10, p. 777-8 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. 2006
  41. Published

    Genome-wide identification of pheromone-targeted transcrption in fission yeast

    Xue-Franzen, Y., Kjærulff, S., Holmberg, Christian, Wright, A. & Nielsen, Olaf, 2006, In: BMC Genomics. 7, p. 303

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. 2005
  43. Published

    Constitutive Activation of the Fission Yeast Pheromone-Responsive Pathway Induces Ectopic Meiosis and Reveals Ste11 as a Mitogen-Activated Protein Kinase Target

    Kjærulff, S., Lautrup-Larsen, I., Truelsen, S., Pedersen, M. & Nielsen, Olaf, 2005, In: Molecular and Cellular Biology. 25, 5, p. 2045-2059

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Ddb1 controls genome stability and meiosis in fission yeast

    Holmberg, Christian, Fleck, O., Hansen, H. A., Liu, C., Slaaby, R., carr, A. M. & Nielsen, Olaf, 2005, In: Genes & Development. 19, 7, p. 853-862

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Mangel på DNA-byggesten kan give kræft.

    Holmberg, Christian & Nielsen, Olaf, 2005, In: Aktuel Naturvidenskab. 3, p. 22-23

    Research output: Contribution to journal › Journal article › Research

  46. Published

    Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase

    Liu, C., Poitelea, M., Watson, A., Yoshida, S., Shimoda, C., Holmberg, Christian, Nielsen, Olaf & Carr, A. M., 2005, In: EMBO Journal. 24, p. 3940-3951

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2004
  48. Published

    DNA repair

    Fleck, O. & Nielsen, Olaf, 1 Feb 2004, In: Journal of Cell Science. 117, Pt 4, p. 515-7 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Mating type Control and differenctiation

    Nielsen, Olaf, 2004, The Molecular Biology of Schizosaccharomyces pombe, genetics, genomics and beyond. Berlin, Springer: <Forlag uden navn>, p. 281-2961

    Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research

  50. Published

    The fission yeast heterochromatin protein Rik1 is required for telomere clustering during meiosis

    Tuzon, C. T., Borgstrøm, B., Weilguny, D., Egel, Richard, Cooper, J. P. & Nielsen, Olaf, 2004, In: Journal of Cell Biology. 165, 6, p. 759-65 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. 2003
  52. Published

    COP9 signalosome: a provider of DNA building blocks

    Nielsen, Olaf, 15 Jul 2003, In: Current Biology. 13, 14, p. R565-7

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. 2002
  54. Published

    The fission yeast ubiquitin-conjugating enzymes UbcP3, Ubc15, and Rhp6 affect transcriptional silencing of the mating-type region

    Nielsen, I. S., Nielsen, Olaf, Murray, J. M. & Thon, Genevieve, 1 Aug 2002, In: Eukaryotic Cell (Online Edition). 1, 4, p. 613-25 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Characterization of meiotic mutants reveals multiole roles for telomeres during meiosis

    Tuzon, C. T., Nielsen, Olaf & Cooper, J. P., 2002.

    Research output: Contribution to conference › Conference abstract for conference › Research

  56. Published

    Characterization of the fission yeast p127 Xeroderma Pigmentosum homologue

    Hansen, H. A., Slaaby, R., Fleck, O. & Nielsen, Olaf, 2002.

    Research output: Contribution to conference › Conference abstract for conference › Research

  57. Published

    Proteins interacting with the forming Fus1

    Bidard, F. & Nielsen, Olaf, 2002.

    Research output: Contribution to conference › Conference abstract for conference › Research

  58. Published

    Regulation of Stell by CDK dependent phosphprylation

    Andersen, N. R., Krause, U. M., Kjærulff, S. & Nielsen, Olaf, 2002.

    Research output: Contribution to conference › Conference abstract for conference › Research

  59. 2000
  60. Published

    Sequence-specific high mobility group box factors recognize 10-12-base pair minor groove motifs

    van Beest, M., Dooijes, D., van De Wetering, M., Kjaerulff, S., Bonvin, A., Nielsen, O., Clevers, H. & Nielsen, Olaf, 1 Sep 2000, In: Journal of Biological Chemistry. 275, 35, p. 27266-73 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma: prognostic significance of E2F-1 and p16INK4A

    Møller, M. B., Kania, Per, Ino, Y., Gerdes, Anne-Marie Axø, Nielsen, Olaf, Louis, D. N., Skjødt, K. & Pedersen, N. T., May 2000, In: Leukemia. 14, 5, p. 898-904 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Mik1 levels accumulate in S phase and may mediate an intrinsic link between S phase and mitosis

    Christensen, P. U., Bentley, N. J., Martinho, R. G., Nielsen, O., Carr, A. & Nielsen, Olaf, 14 Mar 2000, In: Proceedings of the National Academy of Sciences of the United States of America. 97, 6, p. 2579-84 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. 1999
  64. Published

    Den nye arv - historien om dna dna dna ...

    Nielsen, Olaf, 1999, In: Hovedområdet. 3, p. 14-15

    Research output: Contribution to journal › Journal article › Research

  65. 1998
  66. Published

    FH3, a domain found in formins, targets the fission yeast formin Fus1 to the projection tip during conjugation

    Petersen, J., Nielsen, O., Egel, Richard, Hagan, I. M. & Nielsen, Olaf, 1 Jun 1998, In: Journal of Cell Biology. 141, 5, p. 1217-28 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    F-actin distribution and function during sexual differentiation in Schizosaccharomyces pombe

    Petersen, J., Nielsen, O., Egel, Richard, Hagan, I. M. & Nielsen, Olaf, 1 Apr 1998, In: Journal of Cell Science. 111 ( Pt 7), p. 867-76 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. 1997
  69. Published

    Cell differentiation by interaction of two HMG-box proteins: Mat1-Mc activates M cell-specific genes in S.pombe by recruiting the ubiquitous transcription factor Ste11 to weak binding sites

    Kjaerulff, S., Dooijes, D., Clevers, H., Nielsen, O. & Nielsen, Olaf, 1 Jul 1997, In: E M B O Journal. 16, 13, p. 4021-33 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    The Schizosaccharomyces pombe mam1 gene encodes an ABC transporter mediating secretion of M-factor

    Christensen, P. U., Davey, W. J., Nielsen, O. & Nielsen, Olaf, 1 Jun 1997, In: Molecular and General Genetics MGG. 255, 2, p. 226-36 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Identification of the transporter for the M-factor mating pheromone in fission yeast

    Davey, W. J., Christensen, P. U., Nielsen, O. & Nielsen, Olaf, 1 May 1997, In: Biochemical Society Transactions. 25, 2, p. 224S

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Abc1: a new ABC transporter from the fission yeast Schizosaccharomyces pombe

    Christensen, P. U., Davis, K., Nielsen, O., Davey, W. J. & Nielsen, Olaf, 1 Feb 1997, In: F E M S Microbiology Letters. 147, 1, p. 97-102 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Cell differentiation by interaction of two HMG-box proteins: The fission yeast Mat1-Mc protein recruits the Stell transcription factor to weak binding sites

    Kjærulff, S., Dooijes, D., Clevers, H. & Nielsen, Olaf, 1997, Yeast Cell Biology. Cold Spring Harbor Laboratory, p. 128

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  74. Published

    Characterization of cell fusion in Schizosaccharomyces pombe. Abstr. European Congr. for Molecular Cell Biology, Brighton, England, 22.-25. Marts

    Petersen, J., Hagan, I., Egel, R. & Nielsen, Olaf, 1997, ECBO 97. p. 22 (B28)

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

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