Michael Jonathan Davies

Michael Jonathan Davies

Professor

ORCID: 0000-0002-5196-6919

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  1. Quantification of protein modification by oxidants

    Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael Jonathan, 15 Apr 2009, In : Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Quinone-induced protein modifications: kinetic preference for reaction of 1,2-benzoquinones with thiol groups in proteins

    Li, Y., Jongberg, S., Andersen, Mogens Larsen, Davies, Michael Jonathan & Lund, Marianne N., 2016, In : Free Radical Biology & Medicine. 97, p. 148-157 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Radical chemistry of epigallocatechin gallate and its relevance to protein damage

    Hagerman, A. E., Dean, R. T. & Davies, Michael Jonathan, 1 Jun 2003, In : Nitric Oxide: Biology and Chemistry. 414, 1, p. 115-20 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Radicals derived from histone hydroperoxides damage nucleobases in RNA and DNA

    Luxford, C., Dean, R. T. & Davies, Michael Jonathan, Jul 2000, In : Chemical Research in Toxicology. 13, 7, p. 665-72 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Reaction between protein radicals and other biomolecules

    Østdal, H., Davies, Michael Jonathan & Andersen, H. J., 15 Jul 2002, In : Free Radical Biology & Medicine. 33, 2, p. 201-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Reaction of ferric leghemoglobin with H2O2: formation of heme-protein cross-links and dimeric species

    Moreau, S., Davies, Michael Jonathan & Puppo, A., 16 Aug 1995, In : Biochimica et biophysica acta. 1251, 1, p. 17-22 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Reaction of low-molecular-mass organoselenium compounds (and their sulphur analogues) with inflammation-associated oxidants

    Carroll, L., Davies, Michael Jonathan & Pattison, D. I., 2015, In : Free Radical Research. 49, 6, p. 750-767 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation

    Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Aug 2002, In : Biochemical Journal. 365, Pt 3, p. 605-15 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Reaction of quinones with proteins: Kinetics of adduct formation, effects on enzymatic activity and protein structure, and potential reversibility of modifications

    Shu, N., Lorentzen, Lasse Gøbel & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 137, p. 169-180

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids

    Pattison, D. I., Davies, Michael Jonathan & Hawkins, Clare Louise, Aug 2012, In : Free Radical Research. 46, 8, p. 975-95 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Reactive species formed on proteins exposed to singlet oxygen

    Davies, Michael Jonathan, Jan 2004, In : Photochemical & Photobiological Sciences. 3, 1, p. 17-25 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Reactivity of disulfide bonds is markedly affected by structure and environment: implications for protein modification and stability

    Karimi, M., Ignasiak, M. T., Chan, B., Croft, A. K., Radom, L., Schiesser, C. H., Pattison, D. I. & Davies, Michael Jonathan, 12 Dec 2016, In : Scientific Reports. 6, 12 p., 38572.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Reactivity of selenium-containing compounds with myeloperoxidase-derived chlorinating oxidants: Second-order rate constants and implications for biological damage

    Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael Jonathan & Hawkins, Clare Louise, Jul 2015, In : Free Radical Biology & Medicine. 84, p. 279-288 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Reduced metal ion concentrations in atherosclerotic plaques from subjects with type 2 diabetes mellitus

    Stadler, N., Heeneman, S., Vöö, S., Stanley, N., Giles, G. I., Gang, B. P., Croft, K. D., Mori, T. A., Vacata, V., Daemen, M. J. A. P., Waltenberger, J. & Davies, Michael Jonathan, Jun 2012, In : Atherosclerosis. 222, 2, p. 512-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Reevaluation of the rate constants for the reaction of hypochlorous acid (HOCl) with cysteine, methionine, and peptide derivatives using a new competition kinetic approach

    Storkey, C., Davies, Michael Jonathan & Pattison, D. I., Aug 2014, In : Free Radical Biology & Medicine. 73, p. 60-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Regulation and control of nitric oxide (NO) in macrophages: Protecting the "professional killer cell" from its own cytotoxic arsenal via MRP1 and GSTP1

    Kovacevic, Z., Sahni, S., Lok, K. H., Davies, Michael Jonathan, Wink, D. A. & Richardson, D. R., May 2017, In : B B A - Reviews on Cancer. 1861, 5 Pt A, p. 995-999 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3

    Peskin, A. V., Cox, A. G., Nagy, P., Morgan, P. E., Hampton, M. B., Davies, Michael Jonathan & Winterbourn, C. C., 1 Dec 2010, In : Biochemical Journal. 432, 2, p. 313-21 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides

    Winterbourn, C. C., Parsons-Mair, H. N., Gebicki, S., Gebicki, J. M. & Davies, Michael Jonathan, 1 Jul 2004, In : Biochemical Journal. 381, Pt 1, p. 241-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses

    Parker, N. R., Korlimbinis, A., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., Aug 2007, In : Investigative Ophthalmology & Visual Science. 48, 8, p. 3705-13 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Riboflavin-induced Type 1 photo-oxidation of tryptophan using a high intensity 365 nm light emitting diode

    Silva, E., Barrias, P., Fuentes-Lemus, E., Tirapegui, C., Aspee, A., Carroll, L., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Free Radical Biology and Medicine. 131, p. 133-143

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Role of Mitochondrial Reactive Oxygen Species in the Activation of Cellular Signals, Molecules, and Function

    Indo, H. P., Hawkins, Clare Louise, Nakanishi, I., Matsumoto, K., Matsui, H., Suenaga, S., Davies, Michael Jonathan, St Clair, D. K., Ozawa, T. & Majima, H. J., 2017, Pharmacology of Mitochondria. Springer, Vol. 240. p. 439-456 18 p. (Handbook of Experimental Pharmacology, Vol. 240).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  22. Published

    Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?

    Ismael, F. O., Barrett, T. J., Sheipouri, D., Brown, B. E., Davies, Michael Jonathan & Hawkins, Clare Louise, 2016, In : P L o S One. 11, 12, 16 p., e0168844.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Role of di-tyrosine and di-tryptophan in alpha- and beta-casein cross-linking triggered by riboflavin-induced photo oxidation and peroxyl radicals: [Meeting Abstract]

    Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2018, In : Free Radical Biology and Medicine. 120, S1, p. S60-S60 P-50 .

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  24. Published

    Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages

    Guo, Chaorui, Davies, Michael Jonathan & Hawkins, Clare Louise, Sep 2020, In : Redox Biology. 36, 14 p., 101666.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Roles of tyrosine-rich precursor glycoproteins and dityrosine- and 3,4-dihydroxyphenylalanine-mediated protein cross-linking in development of the oocyst wall in the coccidian parasite Eimeria maxima

    Belli, S. I., Wallach, M. G., Luxford, C., Davies, Michael Jonathan & Smith, N. C., Jun 2003, In : Eukaryotic Cell (Online Edition). 2, 3, p. 456-64 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Screening for the metabolic syndrome using simple anthropometric measurements in south Asian and white Europeans: A population-based screening study. The Leicester Ethnic Atherosclerosis and Diabetes Risk (LEADER) Study

    Khunti, K., Taub, N., Tringham, J., Jarvis, J., Farooqi, A., Skinner, Timothy & Davies, Michael Jonathan, 1 Apr 2010, In : Primary Care Diabetes. 4, 1, p. 25-32 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Screening for type 2 diabetes in a multiethnic setting using known risk factors to identify those at high risk: A cross-sectional study

    Gray, L. J., Tringham, J. R., Davies, Michael Jonathan, Webb, D. R., Jarvis, J., Skinner, Timothy, Farooqi, A. M. & Khunti, K., 1 Dec 2010, In : Vascular Health and Risk Management. 6, 1, p. 837-842 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins

    Hazell, L. J., Davies, Michael Jonathan & Stocker, R., 1999, In : Biochemical Journal. 339 ( Pt 3), p. 489-95 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage

    Skaff, O., Pattison, D. I., Morgan, P. E., Bachana, R., Jain, V. K., Priyadarsini, K. I. & Davies, Michael Jonathan, 1 Jan 2012, In : Biochemical Journal. 441, 1, p. 305-16 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Selenium-containing amino acids as direct and indirect antioxidants

    Rahmanto, A. S. & Davies, Michael Jonathan, Nov 2012, In : I U B M B Life. 64, 11, p. 863-71 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins

    Casaril, A. M., Ignasiak, M. T., Chuang, Christine, Vieira, B., Padilha, N. B., Carroll, L., Lenardão, E. J., Savegnago, L. & Davies, Michael Jonathan, Dec 2017, In : Free Radical Biology & Medicine. 113, p. 395-405 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides

    Agon, V. V., Bubb, W. A., Wright, A., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Feb 2006, In : Free Radical Biology & Medicine. 40, 4, p. 698-710 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins

    Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2008, In : Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis

    Morgan, P. E., Sturgess, A. D., Hennessy, A. & Davies, Michael Jonathan, Dec 2007, In : Free Radical Research. 41, 12, p. 1301-12 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Singlet oxygen-mediated damage to proteins and its consequences

    Davies, Michael Jonathan, 6 Jun 2003, In : Molecular Cell Biology Research Communications. 305, 3, p. 761-70 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive peroxides

    Wright, A., Hawkins, C. L. & Davies, Michael Jonathan, 2000, In : Redox Report (Online). 5, 2-3, p. 159-61 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive side chain peroxides on tyrosine residues

    Wright, A., Bubb, W. A., Hawkins, Clare Louise & Davies, Michael Jonathan, Jul 2002, In : Photochemistry and Photobiology. 76, 1, p. 35-46 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products

    Gracanin, M., Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Jul 2009, In : Free Radical Biology & Medicine. 47, 1, p. 92-102 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Site-specific hypochlorous acid-induced oxidation of recombinant human myoglobin affects specific amino acid residues and the rate of cytochrome b5-mediated heme reduction

    Szuchman-Sapir, A. J., Pattison, D. I., Davies, Michael Jonathan & Witting, P. K., 1 Jan 2010, In : Free Radical Biology & Medicine. 48, 1, p. 35-46 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Special issue for the 7th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia 2015 Thailand)

    Ungsurungsie, M., Surh, Y., Toyokuni, S. & Davies, Michael Jonathan, 2 Oct 2016, In : Free Radical Research. 50, 10, p. 1045-1046

    Research output: Contribution to journal › Editorial › Research

  41. Published

    Special issue for the International Conference on Electron Paramagnetic Resonance Spectroscopy and Imaging of Biological Systems (EPR-2017)

    Khramtsov, V. V. & Davies, Michael Jonathan, 2018, In : Free Radical Research. 52, 3, p. 305-306

    Research output: Contribution to journal › Editorial › Research

  42. Published

    Stable markers of oxidant damage to proteins and their application in the study of human disease

    Davies, Michael Jonathan, Fu, S., Wang, H. & Dean, R. T., Dec 1999, In : Free Radical Biology & Medicine. 27, 11-12, p. 1151-63 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Structural and functional changes in RNAse A originating from tyrosine and histidine cross-linking and oxidation induced by singlet oxygen and peroxyl radicals

    Leinisch, F., Mariotti, M., Hägglund, Per Mårten & Davies, Michael Jonathan, Oct 2018, In : Free Radical Biology and Medicine. 126, p. 73-86

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Sulfur and selenium in oxidation protection

    Davies, Michael Jonathan, 2015, In : La chimica e l’industria, Chimica & Materiali. 2015, 6, p. 50-54

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins

    Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 2 Jan 2002, In : FEBS letters. 510, 1-2, p. 41-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Superoxide radicals have a protective role during H2O2 stress

    Thorpe, G. W., Reodica, M., Davies, Michael Jonathan, Heeren, G., Jarolim, S., Pillay, B., Breitenbach, M., Higgins, V. J. & Dawes, I. W., Sep 2013, In : Molecular Biology of the Cell. 24, 18, p. 2876-84 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Superoxide radicals react with peptide-derived tryptophan radicals with very high rate constants to give hydroperoxides as major products

    Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael Jonathan, Apr 2018, In : Free Radical Biology and Medicine. 118, p. 126-136

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Supplementation with carnosine decreases plasma triglycerides and modulates atherosclerotic plaque composition in diabetic apo E(-/-) mice

    Brown, B. E., Kim, C. H. J., Torpy, F. R., Bursill, C. A., McRobb, L. S., Heather, A. K., Davies, Michael Jonathan & van Reyk, D. M., Feb 2014, In : Atherosclerosis. 232, 2, p. 403-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Synthesis and antioxidant capacity of 5-selenopyranose derivatives

    Storkey, C., Davies, Michael Jonathan, White, J. M. & Schiesser, C. H., 14 Sep 2011, In : Chemical communications (Cambridge, England). 47, 34, p. 9693-5 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives

    Borges, E. L., Ignasiak, M. T., Velichenko, Y., Perin, G., Hutton, C. A., Davies, Michael Jonathan & Schiesser, C. H., 25 Mar 2018, In : Chemical Communications. 54, 24, p. 2990-2993

    Research output: Contribution to journal › Journal article › Research › peer-review

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