Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings

    Graham, G. G., Davies, Michael Jonathan, Day, R. O., Mohamudally, A. & Scott, K. F., Jun 2013, In : Inflammopharmacology. 21, 3, p. 201-32 32 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages

    Lane, A. E., Tan, J. T. M., Hawkins, Clare Louise, Heather, A. K. & Davies, Michael Jonathan, 15 Aug 2010, In : Biochemical Journal. 430, 1, p. 161-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The myeloperoxidase-derived oxidant hypothiocyanous acid inhibits protein tyrosine phosphatases via oxidation of key cysteine residues

    Cook, N. L., Moeke, C. H., Fantoni, L. I., Pattison, D. I. & Davies, Michael Jonathan, 1 Jan 2016, In : Free Radical Biology & Medicine. 90, p. 195-205 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. The nitroxide TEMPO is an efficient scavenger of protein radicals: cellular and kinetic studies

    Pattison, D. I., Lam, M., Shinde, S. S., Anderson, R. F. & Davies, Michael Jonathan, 1 Nov 2012, In : Free Radical Biology & Medicine. 53, 9, p. 1664-74 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The nitroxide radical TEMPOL prevents obesity, hyperlipidaemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE(-/-) mice

    Kim, C. H. J., Mitchell, J. B., Bursill, C. A., Sowers, A. L., Thetford, A., Cook, J. A., van Reyk, D. M. & Davies, Michael Jonathan, May 2015, In : Atherosclerosis. 240, 1, p. 234-241 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. The oxidative environment and protein damage

    Davies, Michael Jonathan, 17 Jan 2005, In : B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The peroxyl radical-induced oxidation of Escherichia coli FtsZ and its single tryptophan mutant (Y222W) modifies specific side-chains, generates protein cross-links and affects biological function

    Escobar-Álvarez, E., Leinisch, F., Araya, G., Monasterio, O., Lorentzen, Lasse Gøbel, Silva, E., Davies, Michael Jonathan & López-Alarcón, C., Nov 2017, In : Free Radical Biology and Medicine. 112, p. 60-68 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The prevalence of depression in White-European and South-Asian people with impaired glucose regulation and screen-detected type 2 diabetes mellitus

    Aujla, N., Abrams, K. R., Davies, Michael Jonathan, Taub, N., Skinner, Timothy & Khunti, K., 9 Nov 2009, In : PLoS ONE. 4, 11, e7755.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The prevalence of depressive symptoms in a white European and South Asian population with impaired glucose regulation and screen-detected Type 2 diabetes mellitus: A comparison of two screening tools

    Aujla, N., Skinner, Timothy, Khunti, K. & Davies, Michael Jonathan, 1 Aug 2010, In : Diabetic Medicine. 27, 8, p. 896-905 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The protein oxidation product 3,4-dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage

    Morin, B., Davies, Michael Jonathan & Dean, R. T., 15 Mar 1998, In : Biochemical Journal. 330 ( Pt 3), p. 1059-67 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The retina: oxidative stress and diabetes

    van Reyk, D. M., Gillies, M. C. & Davies, Michael Jonathan, 2003, In : Redox Report (Online). 8, 4, p. 187-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme

    Hawkins, Clare Louise & Davies, Michael Jonathan, Nov 2005, In : Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation

    Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Oct 2005, In : Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling

    Lord, M. S., Chuang, Christine, Melrose, J., Davies, Michael Jonathan, Iozzo, R. V. & Whitelock, J. M., Apr 2014, In : Matrix Biology. 35, p. 112-22 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. The smoking-associated oxidant hypothiocyanous acid induces endothelial nitric oxide synthase dysfunction

    Talib, J., Kwan, J., Suryo Rahmanto, A., Witting, P. K. & Davies, Michael Jonathan, 1 Jan 2014, In : Biochemical Journal. 457, 1, p. 89-97 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The structure of Lactococcus lactis thioredoxin reductase reveals molecular features of photo-oxidative damage

    Skjoldager, N., Blanner Bang, M., Rykaer, M., Björnberg, O., Davies, Michael Jonathan, Svensson, B., Harris, P. & Hägglund, Per Mårten, Apr 2017, In : Scientific Reports. 7, 10 p., 46282.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. The vinyl ether linkages of plasmalogens are favored targets for myeloperoxidase-derived oxidants: a kinetic study

    Skaff, O., Pattison, D. I. & Davies, Michael Jonathan, 5 Aug 2008, In : Biochemistry. 47, 31, p. 8237-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Thiocyanate supplementation decreases atherosclerotic plaque in mice expressing human myeloperoxidase

    Morgan, P. E., Laura, R. P., Maki, R. A., Reynolds, W. F. & Davies, Michael Jonathan, 27 Mar 2015, In : Free Radical Research. 49, 6, p. 743-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants

    Bonifay, V., Barrett, T. J., Pattison, D. I., Davies, Michael Jonathan, Hawkins, Clare Louise & Ashby, M. T., 15 Dec 2014, In : Archives of Biochemistry and Biophysics. 564, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation

    Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael Jonathan, 15 Dec 2008, In : Biochemical Journal. 416, 3, p. 441-52 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage

    Mizdrak, J., Hains, P. G., Truscott, R. J. W., Jamie, J. F. & Davies, Michael Jonathan, 15 Mar 2008, In : Free Radical Biology & Medicine. 44, 6, p. 1108-19 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    UV oxidation of cyclic AMP receptor protein, a global bacterial gene regulator, decreases DNA binding and cleaves DNA at specific sites

    Leinisch, F., Mariotti, M., Andersen, Sofie Hagel, Lindemose, S., Hägglund, Per Mårten, Møllegaard, Niels Erik & Davies, Michael Jonathan, 2020, In : Scientific Reports. 10, 1, 11 p., 3106.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Unexpected light emission from tyrosyl radicals as a probe for tyrosine oxidation

    Ignasiak, M., Frackowiak, K., Pedzinski, T., Davies, Michael Jonathan & Marciniak, B., 2020, In : Free Radical Biology and Medicine. 153, p. 12-16 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Unrestricted Mass Spectrometric Data Analysis for Identification, Localization, and Quantification of Oxidative Protein Modifications

    Rykær, M., Svensson, B., Davies, Michael Jonathan & Hägglund, Per Mårten, 3 Nov 2017, In : Journal of Proteome Research. 16, 11, p. 3978-3988 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Waiting for diabetes: Perceptions of people with pre-diabetes: A qualitative study

    Troughton, J., Jarvis, J., Skinner, Timothy, Robertson, N., Khunti, K. & Davies, Michael Jonathan, 1 Jul 2008, In : Patient Education and Counseling. 72, 1, p. 88-93 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, May 2009, In : Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Whey proteins: targets of oxidation, or mediators of redox protection

    Giblin, L., Yalcin, A. S., Bicim, G., Krämer, Anna Carola, Chen, Z., Callanan, M. J., Arranz, E. & Davies, Michael Jonathan, 2019, In : Free Radical Research. 53, S1, p. 1136–1152 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Xanthine oxidase activity and free radical generation in patients with sepsis syndrome

    Galley, H. F., Davies, Michael Jonathan & Webster, N. R., 1996, In : Critical Care Medicine. 24, 10, p. 1649-53 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    alpha- and beta-casein aggregation induced by riboflavin-sensitized photo-oxidation occurs via di-tyrosine cross-links and is oxygen concentration dependent

    Fuentes-Lemus, E., Silva, E., Leinisch, F., Dorta, E., Lorentzen, Lasse Gøbel, Davies, Michael Jonathan & Lopez-Alarcon, C., 1 Aug 2018, In : Food Chemistry. 256, p. 119-128

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    beta-Scission of C-3 (beta-carbon) alkoxyl radicals on peptides and proteins: a novel pathway which results in the formation of alpha-carbon radicals and the loss of amino acid side chains

    Headlam, H. A., Mortimer, A., Easton, C. J. & Davies, Michael Jonathan, Nov 2000, In : Chemical Research in Toxicology. 13, 11, p. 1087-95 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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