Marco van de Weert
Associate Professor
Drug Delivery and Biophysics of Biopharmaceuticals
Universitetsparken 2, 2100 København Ø
- 2012
- Published
Correlation between enzyme activity and stability of a protease, an alpha-amylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry
Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jorgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents.Research output: Contribution to journal › Journal article › peer-review
- Published
Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry
Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, p. 9-21Research output: Contribution to journal › Journal article › peer-review
- Published
Protease and amylase stability in the presence of chelators used in laundry detergent applications: correlation between chelator properties and enzyme stability in liquid detergents
Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, 3, p. 265-276Research output: Contribution to journal › Journal article › peer-review
- Published
Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy
Maltesen, M. J., van de Weert, Marco & Grohganz, Holger, 2012, In: A A P S PharmSciTech. 13, 3, p. 747-55 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Infrared spectroscopy to characterize protein aggregates
van de Weert, Marco & Jørgensen, Lene, 2012, Analysis of aggregates and particles in protein pharmaceuticals. Mahler, H-C. & Jiskoot, W. (eds.). Hoboken: Wiley, p. 227-248Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2011
- Published
Ionic strength-dependent denaturation of Thermomyces lanuginosus lipase induced by SDS
Fano, M., van de Weert, Marco, Moeller, E. H., Kruse, N. A. & Frøkjær, Sven, 2011, In: Archives of Biochemistry and Biophysics.Research output: Contribution to journal › Journal article › peer-review
- Published
Ionic strength-dependent denaturation ofThermomyces lanuginosus llipase induced by SDS
Fanø, M., van de Weert, Marco, Møller, E. H., Kruse, N. A. & Frøkjær, Sven, 2011, In: Archives of Biochemistry and Biophysics. 506, 1, p. 92-98Research output: Contribution to journal › Journal article › peer-review
- Published
Protein adsorption at charged surfaces: the role of electrostatic interactions and interfacial charge regulation
Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, Henrik Elvang, 15 Mar 2011, In: Langmuir. 27, 6, p. 2634-2643 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Protein adsorption at charged surfaces: The role of electrostatic interactions and interacial charge regulation
Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2011, In: Langmuir. 27, p. 2634-2643Research output: Contribution to journal › Journal article › peer-review
- Published
Self-association of long-acting insulin analogues studied by size exclusion chromatography coupled to multi-angle light scattering
Jensen, M. H., Wahlund, P., Jacobsen, J. K., Vestergaard, Bente, van de Weert, Marco & Havelund, S., 2011, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 879, 28, p. 2945-2951Research output: Contribution to journal › Journal article › peer-review
- Published
Multivariate analysis of phenol in freeze-dried and spray-dried insulin formulations by NIR and FTIR
Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S., van de Weert, Marco & Grohganz, Holger, 2011, In: A A P S PharmSciTech. 12, 2, p. 627-635Research output: Contribution to journal › Journal article › peer-review
- Published
Thermal and acid denaturation of bovine lens a-crystallin
Rasmussen, T., van de Weert, Marco, Jiskoot, W. & Kasimova, M. R., 2011, In: Proteins - Structure Function and Bioinformatics. 79, 6, p. 1747-1758Research output: Contribution to journal › Journal article › peer-review
- Published
Erratum: Fluorescence quenching to study protein-ligand binding: Common errors (Journal of Fluorescence (2010) 20 (625-629)DOI 10.1007/s10895-009-0572- x)
van de Weert, Marco, 29 Aug 2011, In: Journal of Fluorescence. 21, 6, 1 p.Research output: Contribution to journal › Comment/debate › peer-review
- Published
Fluorescence quenching and ligand binding: A critical discussion of a popular methodology
van de Weert, Marco & Stella, L., 2011, In: Journal of Molecular Structure: THEOCHEM. 998, 1-3, p. 144-150Research output: Contribution to journal › Journal article › peer-review
- 2010
- Published
Large-scale polymorphism and auto-catalytic effect in insulin fibrillogenesis
Foderà, Vito, van de Weert, Marco & Vestergaard, Bente, 2010, In: Soft Matter. 6, 18, p. 4413-4419Research output: Contribution to journal › Journal article › peer-review
- Published
Interfacial complexes between a protein and lipophilic ions at an oil - water interface
Hartvig, R. A., Méndez, M. A., van de Weert, Marco, Jørgensen, Lene, Østergaard, Jesper, Girault, H. H. & Jensen, H., 2010, In: Analytical Chemistry. 82, 18, p. 7699-7705Research output: Contribution to journal › Journal article › peer-review
- Published
The molecular chaperone a-crystallin as an excipient in an insulin formulation
Rasmussen, T., Tantipolphan, R., van de Weert, Marco & Jiskoot, W., 2010, In: Pharmaceutical Research. 27, p. 1337-1347Research output: Contribution to journal › Journal article › peer-review
- Published
Fluorescence quenching to study protein-ligand binding: Common errors
van de Weert, Marco, 2010, In: Journal of Fluorescence. 20, p. 625-629Research output: Contribution to journal › Journal article › peer-review
- 2009
- Published
Determination of dissociation constants between polyelectrolytes and proteins by affinity capillary electrophoresis
Anderot, M., Nilsson, M., Végvári, Á., Møller, E. H., van de Weert, Marco & Isaksson, R., 2009, In: Journal of Chromatography - B. 877, p. 892-896Research output: Contribution to journal › Journal article › peer-review
- Published
Analysis of protein physical stability in lipid based delivery systems: the challenges of lipid drug delivery systems
Jørgensen, Lene, Martins, S. & van de Weert, Marco, 2009, In: Journal of Biomedical Nanotechnology. 5, 4, p. 401-408Research output: Contribution to journal › Journal article › peer-review
- Published
Analysis of insulin allostery in solution and solid state with FTIR
Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S. & van de Weert, Marco, 2009, In: Journal of Pharmaceutical Sciences. 98, 9, p. 3265-3277Research output: Contribution to journal › Journal article › peer-review
- Published
The chaperone-like protein a-crystallin dissociates insulin dimers and hexamers
Rasmussen, T., Kasimova, M. R., Jiskoot, W. & van de Weert, Marco, 2009, In: Biochemistry. 48, p. 9313-9320Research output: Contribution to journal › Journal article › peer-review
- Published
Delivery technologies for biopharmaceuticals: a critical assessment
van de Weert, Marco, 2009, Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines. Jørgensen, L. & Mørck Nielsen, H. (eds.). Chichester: Wiley, p. 407-411Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Infrared spectroscopy of protein pharmaceuticals
van de Weert, Marco & Jørgensen, Lene, 2009, Advances in Biomedical Spectroscopy: Biological and Biomedical Infrared Spectrocopy. Barth, A. & Haris, P. I. (eds.). Amsterdam: IOS Press, Vol. 2. p. 168-177Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- 2008
- Published
Secondary nucleation and accessible surface in insulin amyloid fibril formation
Foderà, Vito, Librizzi, F., Jensen, M. G., van de Weert, Marco & Leone, M., 2008, In: Journal of Physical Chemistry B. 112, 12, p. 3853-3858Research output: Contribution to journal › Journal article › peer-review
- Published
Thioflavin T hydroxylation at basic pH and its effect on amyloid fibril detection
Foderà, Vito, Jensen, M. G., Vetri, V., Librizzi, F., Spagnolo, S., Cornett, Claus, Olsen, L., van de Weert, Marco & Leone, M., 2008, In: Journal of Physical Chemistry. 112, 47, p. 15174-15181Research output: Contribution to journal › Journal article › peer-review
- Published
Drying methods for protein pharmaceuticals
Maltesen, M. J. & van de Weert, Marco, 2008, In: Drug Discovery Today: Technologies. 5, 2-3, p. 81-88Research output: Contribution to journal › Review › peer-review
- Published
Quality by design: Spray drying of insulin intended for inhalation
Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S. & van de Weert, Marco, 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 70, 3, p. 828-838Research output: Contribution to journal › Journal article › peer-review
- Published
Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach
Thomsen, A. E., Jensen, H., Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In: Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248Research output: Contribution to journal › Journal article › peer-review
- Published
Immunogenicity of biopharmaceuticals: methods to reduce immunogenicity and biosimilars
van de Weert, Marco & Møller, E. H., 2008, Immunogenicity of biopharmaceuticals. van de Weert, M. & Møller, E. H. (eds.). 1 ed. New York: Springer, p. 97-111Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Preface
van de Weert, Marco & Møller, E. H., 2008, Immunogenicity of biopharmaceuticals. van de Weert, M. & Møller, E. H. (eds.). 1 ed. New York: Springer, p. v-viResearch output: Chapter in Book/Report/Conference proceeding › Preface/postscript › Research
- Published
Protein pharmaceuticals
van de Weert, Marco & Møller, E. H., 2008, In: Drug Discovery Today: Technologies. 5, 2-3, p. 35-36Research output: Contribution to journal › Editorial
- 2007
- Published
Binding mode of Thioflavin T in insulin amyloid fibrils
Jensen, M. G., Norrman, M., Flink, J. M., van de Weert, Marco, Bukrinsky, J. T., Schluckebier, G. & Frøkjær, Sven, 2007, In: Journal of Structural Biology. 159, 3, p. 483-497Research output: Contribution to journal › Journal article › peer-review
- Published
- Published
Study on the binding of Thioflavin T to ß-sheet-rich and non-ß-sheet cavities
Jensen, M. G., Olsen, L., van de Weert, Marco, Flink, J. M., Frøkjær, Sven & Jørgensen, Flemming Steen, 2007, In: Journal of Structural Biology. 158, 3, p. 358-369Research output: Contribution to journal › Journal article › peer-review
- Published
Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles
Sarmento, B., Ferreira, D. C., Jørgensen, Lene & van de Weert, Marco, 2007, In: European Journal of Pharmaceutics and Biopharmaceutics. 65, 1, p. 10-17Research output: Contribution to journal › Journal article › peer-review
- Published
Characterisation and physical stability of PEGylated glucagon
Stigsnæs, P., Frøkjær, Sven, Bjerregaard, S., van de Weert, Marco, Kingshott, P. & Møller, E. H., 2007, In: Internation Journal of Pharmaceutics. 330, 1-2, p. 89-98Research output: Contribution to journal › Journal article › peer-review
- Published
A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils
Vestergaard, Bente, Jensen, M. G., Roessle, M., Kastrup, Jette Sandholm Jensen, van de Weert, Marco, Flink, J. M., Frøkjær, Sven, Gajhede, Michael & Svergun, D. I., 2007, In: PLoS - Biology. 5, 5, p. 1089-1097Research output: Contribution to journal › Journal article › peer-review
- Published
Bioinformatic and experimental analysis of the secondary structure of amelogenin
Vilhjalmsson, B., Rasmussen, Anne, Fabi, B., van de Weert, Marco, Hamelryck, Thomas Wim & Lemoult, S., 1 Nov 2007, In: European Cells and Materials. 14, SUPPL.2, 1 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Characterisation of salmon calcitonin in spray-dried powder for inhalation. Effect of chitosan
Yang, Mingshi, Velaga, S., Yamamoto, H., Takeuchi, H., Kawashima, Y., Hovgaard, L., van de Weert, Marco & Frøkjær, Sven, 2007, In: Internation Journal of Pharmaceutics. 331, 2, p. 176-181Research output: Contribution to journal › Journal article › peer-review
- Published
Characterization of a cyclosporine solid dispersion for inhalation
Zijlstra, G. S., Rijkeboer, M., van Drooge, D. J., Sutter, M., Jiskoot, W., van de Weert, Marco, Hinrichs, W. L. J. & Frijlink, H. W., 2007, In: The AAPS journal. 9, 2, p. E190-E199Research output: Contribution to journal › Journal article › peer-review
- 2006
- Published
Chemical and thermal stability of insulin: effects of zinc and ligand binding to the insulin zinc-hexamer
Huus, K., Havelund, S., Olsen, H. B., van de Weert, Marco & Frøkjær, Sven, Nov 2006, In: Pharmaceutical Research. 23, 11, p. 2611-20 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Ligand binding and thermostability of different allosteric states of the insulin zinc-hexamer
Huus, K., Havelund, S., Olsen, H. B., Sigurskjold, B. W., van de Weert, Marco & Frøkjær, Sven, 28 Mar 2006, In: Biochemistry. 45, 12, p. 4014-4024 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Preparing and evaluating delivery systems for proteins
Jorgensen, L., Moeller, E. H., van de Weert, Marco, Nielsen, H. M. & Frøkjær, Sven, 2006, In: European Journal of Pharmaceutical Sciences. 29, 3-4, p. 174-82 9 p.Research output: Contribution to journal › Review › peer-review
- 2005
- Published
Thermal dissociation and unfolding of insulin
Huus, K., Havelund, S., Olsen, H. B., van de Weert, Marco & Frøkjær, Sven, 23 Aug 2005, In: Biochemistry. 44, 33, p. 11171-7 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Evaluation of statistical design/modeling for prediction of the effect of amino acids on agitation-induced aggregation of human growth hormone and human insulin
Soenderkaer, S., van de Weert, Marco, Lindgaard Hansen, L., Flink, J. & Frøkjær, Sven, 2005, In: Journal of Drug Delivery Science and Technology. 15, 6, p. 427-434 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Complex coacervation with heparin results in decreased lysozyme stability
van de Weert, Marco, Bendix Andersen, M. & Frøkjær, Sven, 3 Jan 2005, In: Journal of controlled release : official journal of the Controlled Release Society. 101, 1-3, p. 361-2 2 p.Research output: Contribution to journal › Conference abstract in journal
- Published
Factors of importance for a successful delivery system for proteins
van de Weert, Marco, Jørgensen, Lene, Horn Moeller, E. & Frøkjær, Sven, Nov 2005, In: Expert Opinion on Drug Delivery. 2, 6, p. 1029-37 9 p.Research output: Contribution to journal › Review › peer-review
- Published
Fourier transform infrared spectroscopy of protein formulations
van de Weert, Marco, Hering, J. A. & Haris, P. I., 2005, Methods for Structural Analysis of Protein Pharmaceuticals. Jiskoot, W. & Crommelin, D. (eds.). Arlington: Springer Science+Business Media, p. 131-166Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- 2004
- Published
Formulation, stability and characterization of protein and peptide drugs
Frøkjær, Sven, Hovgaard, L. & van de Weert, Marco, 2004, Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids. Mahato, R. I. (ed.). Boca Raton: CRC Press, p. 378-401Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
ID: 1302800
Most downloads
-
401
downloads
Preferential interactions and the effect of protein PEGylation
Research output: Contribution to journal › Journal article › peer-review
Published -
394
downloads
On the purported "backbone fluorescence" in protein three-dimensional fluorescence spectra
Research output: Contribution to journal › Journal article › peer-review
Published -
250
downloads
Rhamnogalacturonan-I based microcapsules for targeted drug release
Research output: Contribution to journal › Journal article › peer-review
Published