Leise Riber

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Current research

Interactions of bacterial communities and prevalence of antimicrobial resistance genes in natural environments. Molecular mechanisms involved in spread and acquisition of antibiotics resistance through horizontal gene transfer among bacterial populations. Dynamics of plasmid transfer and stability within bacterial species in complex environments. Transfer frequencies and host range of various conjugative plasmids are studied by a cultivation independent single cell based transfer-reporter gene approach using the Green Fluorescent Protein (GFP) together with Fluorescence-activated cell sorting (FACS).

Molecular microbiology; Construction and optimization of molecular methods for tagging plasmids and bacterial chromosomes for use in the transfer-reporter gene based system when studying horizontal gene transfer on a single cell level.

Plasmid biology; Studying and characterizing environmental conjugative plasmids with respect to finding gene determinants involved in plasmid dependent regulation of biofilm formation and plasmid transfer.

Selected publications

1. Coordinated replication and sequestration of oriC and dnaA are required for maintaining controlled once-per-cell-cycle initiation in Escherichia coli

   Riber, Leise & Løbner-Olesen, Anders, 1 Aug 2005, In: Journal of Bacteriology. 187, 16, p. 5605-5613 9 p.

   Research output: Contribution to journal › Journal article › Research › peer-review

2. Suppressors of DnaA^ATP imposed overinitiation in Escherichia coli

   Charbon, G., Riber, Leise, Cohen, M., Skovgaard, O., Fujimitsu, K., Katayama, T. & Løbner-Olesen, Anders, 2011, In: Molecular Microbiology. 79, 4, p. 914-928 15 p.

   Research output: Contribution to journal › Journal article › Research › peer-review

3. Published

   Centre for Anti-resistance; Limiting the occurrence of antimicrobial resistance through targeted interventions directed at plasmid transfer and stability

   Riber, Leise, Burmølle, Mette, Hansen, Lars Hestbjerg & Sørensen, Søren Johannes, 2010.

   Research output: Contribution to conference › Poster › Research