Kristian Strømgaard
Professor
Biopharmaceuticals
Jagtvej 162
2100 København Ø
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Uncompetitive antagonism of AMPA receptors: Mechanistic insights from studies of polyamine toxin derivatives
Andersen, T. F., Tikhonov, D. B., Bølcho, U., Bolshakov, K., Nelson, J. K., Pluteanu, F., Mellor, I. R., Egebjerg, J. & Strømgaard, Kristian, 7 Sep 2006, In: Journal of Medicinal Chemistry. 49, 18, p. 5414-5423 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Unaturlige aminosyrer skaber ny viden om proteiner
Rannes, J., Andersen, J., Jensen, Anders A., Christensen, L. & Strømgaard, Kristian, 2006, In: Lægemiddelforskning. p. 28-29Research output: Contribution to journal › Journal article › Communication
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UCCB01-125, a dimeric inhibitor of PSD-95, reduces inflammatory pain without disrupting cognitive or motor performance: Comparison with the NMDA receptor antagonist MK-801
Andreasen T., Jesper, Bach, Anders, Gynther, M., Nasser, A., Mogensen, J., Strømgaard, Kristian & Pickering, Darryl S, Apr 2013, In: Neuropharmacology. 67, p. 193-200 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Total synthesis and structure–activity relationship studies of a series of selective G protein inhibitors
Xiong, X., Zhang, H., Underwood, C. R., Harpsøe, Kasper, Gardella, T. J., Wöldike, M. F., Mannstadt, M., Gloriam, David E., Bräuner, Hans & Strømgaard, Kristian, 2016, In: Nature Chemistry. 8, 11, p. 1035-1041 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tight control of the APP-Mint1 interaction in regulating amyloid production
Henry, S. M., Kistler, S. A., Lagani, G. D., Bartling, Christian Reinhard Otto, Özcelik, D., Sereikaité, Vita, Strømgaard, Kristian, Beffert, U. & Ho, A., 2023, In: Brain Research. 1817, 6 p., 148496.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of backbone hydrogen bonds in the transition state for protein folding of a PDZ domain
Pedersen, S. W., Hultqvist, G., Strømgaard, Kristian & Jemth, P., 2014, In: PLOS ONE. 9, 4, p. 1-7 7 p., e95619.Research output: Contribution to journal › Journal article › Research › peer-review
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The Effects of Lipidation on a TAT-Containing Peptide-Based Inhibitor of PSD-95
Alves Fernandes, Eduardo Felipe, Haugaard-Kedstroem, L. M. & Strømgaard, Kristian, 2020, In: Australian Journal of Chemistry. 73, 4, p. 307-311 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Textbook of drug design and discovery
Krogsgaard-Larsen, Povl, Strømgaard, Kristian & Madsen, Ulf, 2010, 4 ed. Boca Raton: CRC Press. 460 p.Research output: Book/Report › Book › Education
Terpene trilactones from Ginkgo biloba are antagonists of cortical glycine and GABA(A) receptors
Ivic, L., Sands, T. T. J., Fishkin, N., Nakanishi, K., Kriegstein, A. R. & Strømgaard, Kristian, 5 Dec 2003, In: Journal of Biological Chemistry. 278, 49, p. 49279-49285 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting the gamma-Aminobutyric Acid Type B (GABA(B)) Receptor Complex: Development of Inhibitors Targeting the K+ Channel Tetramerization Domain (KCTD) Containing Proteins/GABA(B) Receptor Protein-Protein Interaction
Sereikaité, Vita, Fritzius, T., Kasaragod, V. B., Bader, N., Maric, H. M., Schindelin, H., Bettler, B. & Strømgaard, Kristian, 2019, In: Journal of Medicinal Chemistry. 62, 19, p. 8819-8830Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting the APP-Mint2 Protein-Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid-β Formation
Bartling, Christian Reinhard Otto, Jensen, T. M. T., Henry, S. M., Colliander, A. L., Sereikaité, Vita, Wenzler, M., Jain, P., Maric, H. M., Harpsøe, Kasper, Pedersen, S. W., Clemmensen, L. S., Haugaard-Kedström, L. M., Gloriam, David E., Ho, A. & Strømgaard, Kristian, 2021, In: Journal of the American Chemical Society. 143, 2, p. 891-901Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting receptor complexes: a new dimension in drug discovery
Rosenbaum, M. I., Clemmensen, L. S., Bredt, D. S., Bettler, B. & Strømgaard, Kristian, 2020, In: Nature Reviews. Drug Discovery. 19, p. 884-901 18 p.Research output: Contribution to journal › Review › Research › peer-review
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Fadahunsi, N., Petersen, J. O., Metz, S., Jakobsen, A., Mathiesen, C. V., Buch-Rasmussen, A. S., Kurgan, N. K., Larsen, J. K., Andersen, R. C., Topilko, T., Svendsen, C., Apuschkin, M., Skovbjerg, G., Schmidt, J. H., Houser, G. A., Jager, S. E., Bach, A., Deshmukh, A. S., Kilpeläinen, T. O., Strømgaard, K. & 2 others, , 2024, In: Science Advances. 10, 9, 20 p., eadg2636.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting Protein-Protein Interactions with Trimeric Ligands: High Affinity Inhibitors of the MAGUK Protein Family
Nissen, K. B., Kedström, L. M. H., Wilbek, T. S., Nielsen, L. S., Åberg, E., Kristensen, Anders Skov, Bach, Anders, Jemth, P. & Strømgaard, Kristian, 2015, In: PLOS ONE. 10, 2, p. 1-17 17 p., e0117668.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting PSD-95 as a Novel Approach in the Treatment of Stroke
Haugaard-Kedstrom, L. M., Fernandes, E. F. A. & Strømgaard, Kristian, 2017, Neuroprotective Therapy for Stroke and Ischemic Disease . Springer, p. 157-184 28 p. (Springer Series in Translational Stroke Research).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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THE DEVELOPMENT AND CHARACTERIZATION OF A PEPTIDE-BASED SYNTENIN INHIBITOR - IMPLACATIONS FOR CANCER METASTASIS
Haugaard-Kedstrom, L. M., Albertsen, L., Gil, F. A., Ivarsson, Y., Strømgaard, Kristian & Kedström, L. M. H., Sep 2014, In: Journal of Peptide Science. 20, Suppl. 1, p. s39 1 p., YO11.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Synthetic and mechanistic insight into nosylation of glycine residues
Stuhr-Hansen, N., Sølling, Theis Ivan & Strømgaard, Kristian, 14 Apr 2013, In: Organic & Biomolecular Chemistry. 11, 14, p. 2288-2293 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis of symmetrical and non-symmetrical bivalent neurotransmitter ligands
Stuhr-Hansen, N., Andersen, J., Thygesen, Mikkel Boas & Strømgaard, Kristian, 2016, In: ChemistrySelect. 1, 3, p. 407-413 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis of polyamines and polyamine toxins. An improved alkylation procedure
Strømgaard, Kristian & Andersen, T., 2004, In: Tetrahedron Letters. 45, p. 7929-7933Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis of peptides using tert-butyloxycarbonyl (Boc) as the α-amino protection group
Pedersen, S. W., Armishaw, C. J. & Strømgaard, Kristian, 2013, Peptide synthesis and applications. Humana Press, Vol. 1047. p. 65-80 16 p. (Methods in Molecular Biology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Synthesis and biological activity of novel a-conotoxin analogues incorporating substituted proline derivatives
Armishaw, C., Jensen, Anders A., Skonberg, C., Liljefors, T. & Strømgaard, Kristian, 2009, Peptides for youth: The proceedings of the 20th American peptide symposium. Del Valle, S., Escher, E. & Lubell, W. D. (eds.). Springer, Vol. 611. p. 179-180 (Advances in Experimental Medicine and Biology, Vol. 611).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
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Synthesis and biological activity of argiotoxin 636 and analogues: selective antagonists for ionotropic glutamate receptors
Nelson, J. K., Frølund, S. U., Tikhonov, D. B., Kristensen, Anders Skov & Strømgaard, Kristian, 2009, In: Angewandte Chemie - International Edition. 48, 17, p. 3087-3091Research output: Contribution to journal › Journal article › Research › peer-review
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Subunit-Dependent Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Philanthotoxins
Kachel, H. S., Franzyk, Henrik, Strømgaard, Kristian, Tikhonov, D. B. & Mellor, I. R., 28 Jan 2014, In: Biophysical Society. Annual Meeting. Abstracts. 106, 2, p. 338A-338A 1 p.Research output: Contribution to journal › Journal article › Research
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Structure–activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359
Zhang, H., Nielsen, A. L., Boesgaard, M. W., Harpsøe, Kasper, Daly, N. L., Xiong, X., Underwood, C. R., Haugaard-kedström, L. M., Bräuner, Hans, Gloriam, David E. & Strømgaard, Kristian, 2018, In: European Journal of Medicinal Chemistry. 156, p. 847-860Research output: Contribution to journal › Journal article › Research › peer-review
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Structure–Activity Relationship Study of Spider Polyamine Toxins as Inhibitors of Ionotropic Glutamate Receptors
Xiong, X., Poulsen, Mette Homann, Hussein, R. A., Nørager, N. G. & Strømgaard, Kristian, Dec 2014, In: ChemMedChem. 9, 12, p. 2661-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302559
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PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
Research output: Contribution to journal › Journal article › Research › peer-review
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