Kristian Strømgaard

Kristian Strømgaard

Professor


  1. Published

    Comparing the binding properties of peptides mimicking the Envelope protein of SARS-CoV and SARS-CoV-2 to the PDZ domain of the tight junction-associated PALS1 protein

    Toto, A., Ma, S., Malagrinò, F., Visconti, L., Pagano, L., Strømgaard, Kristian & Gianni, S., 2020, In: Protein Science. 29, 10, p. 2038-2042 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2

    Bartling, Christian Reinhard Otto, Alexopoulou, Flora, Kuschert, S., Chin, Y. K. Y., Jia, X., Sereikaité, Vita, Özcelik, D., Jensen, T. M., Jain, P., Nygaard, M. M., Harpsøe, Kasper, Gloriam, David E., Mobli, M. & Strømgaard, Kristian, 2023, In: Journal of Medicinal Chemistry. 66, 4, p. 3045-3057

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Conjugation of Therapeutic PSD-95 Inhibitors to the Cell-Penetrating Peptide Tat Affects Blood-Brain Barrier Adherence, Uptake, and Permeation

    Kristensen, Mie, Kucharz, Krzysztof, Alves Fernandes, Eduardo Felipe, Strømgaard, Kristian, Schallburg Nielsen, M., Cederberg Helms, H. C., Bach, Anders, Ulrikkaholm Tofte-Hansen, M., Aldana, Blanca, Lauritzen, Martin & Larsen, Birger Brodin, 2020, In: Pharmaceutics. 12, 7, 24 p., 661.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Contrasting actions of philanthotoxin-343 and philanthotoxin-(12) on human muscle nicotinic acetylcholine receptors

    Brier, T. J., Mellor, I. R., Tikhonov, D. B., Neagoe, I., Shao, Z., Brierley, M. J., Strømgaard, Kristian, Jaroszewski, J. W., Krogsgaard-Larsen, Povl & Usherwood, P. N. R., Oct 2003, In: Molecular Pharmacology. 64, 4, p. 954-964 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Controlling Ca2+ Permeable alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Photochromic Ion Channel Blockers

    Norager, N. G., Poulsen, Mette Homann & Strømgaard, Kristian, 13 Sep 2018, In: Journal of Medicinal Chemistry. 61, 17, p. 8048-8053

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example

    Chi, C. N., Bach, Anders, Gottschalk, M., Kristensen, Anders Skov, Strømgaard, Kristian & Jemth, P., 2010, In: Journal of Biological Chemistry. 285, 36, p. 28252-28260

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors

    Maric, H., Kasaragod, V. B., Kedström, L. M. H., Hausrat, T. J., Kneussel, M., Schindelin, H. & Strømgaard, Kristian, 7 Jan 2015, In: Angewandte Chemie (International ed. in English). 54, 2, p. 490-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction

    Bach, Anders, Chi, C. N., Pang, G. F., Olsen, L., Kristensen, Anders Skov, Jemth, P. & Strømgaard, Kristian, 2009, In: Angewandte Chemie - International Edition. 48, 51, p. 9685-9689

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist

    Andersen, T. F., Vogensen, S. B., Jensen, L. S., Knapp, K. M. & Strømgaard, Kristian, 1 Sep 2005, In: Bioorganic & Medicinal Chemistry. 13, 17, p. 5104-5112 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Design and synthesis of peptide YY analogues with c-terminal backbone amide-to-ester modifications

    Albertsen, L., Andersen, J. J., Paulsson, J. F., Thomsen, J. K., Norrild, J. C. & Strømgaard, Kristian, 12 Dec 2013, In: A C S Medicinal Chemistry Letters. 4, 12, p. 1228-1232 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Design and synthesis of triazole-based peptidomimetics of a PSD-95 PDZ domain inhibitor

    Bach, Anders, Pedersen, T. B. & Strømgaard, Kristian, 2016, In: MedChemComm. 7, 3, p. 531-536 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Design, Synthesis, and Characterization of Fatty Acid Derivatives of a Dimeric Peptide-Based Postsynaptic Density-95 (PSD-95) Inhibitor

    Nissen, K. B., Andersen, J. J., Haugaard-Kedström, L. M., Bach, Anders & Strømgaard, Kristian, 2015, In: Journal of Medicinal Chemistry. 58, p. 1575-1580 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Design, synthesis, and pharmacological characterization of polyamine toxin derivatives: potent ligands for the pore-forming region of AMPA receptors

    Jensen, L. S., Bølcho, U., Egebjerg, J. & Strømgaard, Kristian, Apr 2006, In: ChemMedChem. 1, 4, p. 419-428 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Designing Poly-agonists for Treatment of Metabolic Diseases: Challenges and Opportunities

    Petersen, Jonas Odgaard, Strømgaard, Kristian, Frølund, Bente & Clemmensen, Christoffer, 2019, In: Drugs. 79, 11, p. 1187-1197 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Detecting protein-protein interactions in living cells: development of a bioluminescence resonance energy transfer assay to evaluate the PSD-95/NMDA receptor interaction

    Gottschalk, M., Bach, Anders, Hansen, J. L., Krogsgaard-Larsen, Povl, Kristensen, Anders Skov & Strømgaard, Kristian, 2009, In: Neurochemical Research. 34, 10, p. 1729-1737

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Development of a Potent Cyclic Peptide Inhibitor of the nNOS/PSD-95 Interaction

    Balboa, J. R., Essig, D. J., Ma, S., Karer, N., Clemmensen, L. S., Pedersen, S. W., Joerger, A. C., Knapp, S., Østergaard, S. & Strømgaard, Kristian, 2023, In: Journal of Medicinal Chemistry. 66, 1, p. 976-990

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Development of potent fluorescent polyamine toxins and application in labeling of ionotropic glutamate receptors in hippocampal neurons

    Nørager, N. G., Jensen, C. B., Rathje, Mette, Andersen, J., Madsen, Kenneth Lindegaard, Kristensen, Anders Skov & Strømgaard, Kristian, 20 Sep 2013, In: A C S Chemical Biology. 8, 9, p. 2033-2041 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Effects of dimeric PSD-95 inhibition on excitotoxic cell death and outcome after controlled cortical impact in rats: PSD-95 inhibition in experimental TBI

    Sommer, J. B., Bach, Anders, Rytter, Hana Malá, Gynther, M., Bjerre, A., Gram, M. G., Marschner, L., Strømgaard, Kristian, Mogensen, J. & Pickering, Darryl S, 2017, In: Neurochemical Research. 42, 12, p. 3401-3413 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Effects of the dimeric PSD-95 inhibitor UCCB01-144 in mouse models of pain, cognition and motor function

    Andreasen T., Jesper, Nasser, A., Caballero-Puntiverio, M., Sahlholt, M., Bach, Anders, Gynther, M., Strømgaard, Kristian & Pickering, Darryl S, 5 Jun 2016, In: European Journal of Pharmacology. 780, p. 166-73 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Effects of the dimeric PSD-95 inhibitor UCCB01-144 on functional recovery after fimbria-fornix transection in rats

    Sommer, J. B., Bach, Anders, Rytter, Hana Malá, Strømgaard, Kristian, Mogensen, J. & Pickering, Darryl S, Oct 2017, In: Pharmacology, Biochemistry and Behavior. 161, p. 62-67 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Energetic pathway sampling in a protein interaction domain

    Hultqvist, G., Haq, S. R., Punekar, A. S., Chi, C. N., Engström, A., Bach, Anders, Strømgaard, Kristian, Selmer, M., Gianni, S. & Jemth, P., 25 Jun 2013, In: Structure. 21, 7, p. 1193-1202

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Evaluation of PhTX-74 as Subtype-Selective Inhibitor of GluA2-Containing AMPA Receptors

    Poulsen, Mette Homann, Lucas, S., Strømgaard, Kristian & Kristensen, Anders Skov, Feb 2014, In: Molecular Pharmacology. 85, 2, p. 261-268 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Expedient synthesis of 1,3-substituted benzene peptidomimetics

    Bach, Anders & Strømgaard, Kristian, 8 Feb 2011, In: Synthesis. 2011, 5, p. 807-815

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Expressed protein ligation of ionotropic glutamate receptors

    Jensen, M. S., Kristensen, Anders Skov & Strømgaard, Kristian, 2007, In: Biopolymers. 88, 4, p. 602

    Research output: Contribution to journalConference abstract in journalResearch

  25. Published

    Facile synthesis of α-hydroxy carboxylic acids from the corresponding α-amino acids

    Stuhr-Hansen, N., Padrah, S. & Strømgaard, Kristian, 2014, In: Tetrahedron Letters. 55, 30, p. 4149-4151 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302559