Klaus Bønnelykke

Klaus Bønnelykke

Clinical Professor

Member of:

  • Paediatrics


  1. 2022
  2. Published

    A genome-wide association study of total child psychiatric problems scores

    Neumann, A., Nolte, I. M., Pappa, I., Ahluwalia, T. S., Pettersson, E., Rodriguez, A., Whitehouse, A., van Beijsterveldt, C. E. M., Benyamin, B., Hammerschlag, A. R., Helmer, Q., Karhunen, V., Krapohl, E., Lu, Y., van der Most, P. J., Palviainen, T., Pourcain, B. S., Seppälä, I., Suarez, A., Vilor-Tejedor, N. & 41 others, Tiesler, C. M. T., Wang, C., Wills, A., Zhou, A., Alemany, S., Bisgaard, H., Bønnelykke, Klaus, Davies, G. E., Hakulinen, C., Henders, A. K., Hyppönen, E., Stokholm, Jakob, Bartels, M., Hottenga, J., Heinrich, J., Hewitt, J., Keltikangas-Järvinen, L., Korhonen, T., Kaprio, J., Lahti, J., Lahti-Pulkkinen, M., Lehtimäki, T., Middeldorp, C. M., Najman, J. M., Pennell, C., Power, C., Oldehinkel, A. J., Plomin, R., Räikkönen, K., Raitakari, O. T., Rimfeld, K., Sass, L., Snieder, H., Standl, M., Sunyer, J., Williams, G. M., Bakermans-Kranenburg, M. J., Boomsma, D. I., van IJzendoorn, M. H., Hartman, C. A. & Tiemeier, H., 2022, In: PLoS ONE. 17, 8, 23 p., e0273116.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A saturated map of common genetic variants associated with human height

    Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y. & 37 others, Karaderi, Tugce, Lin, K., Lull, K., Malden, D. E., Lepola, Mette Andersen, Appadurai, V., Bork-Jensen, J., Burgdorf, Kristoffer Sølvsten, Hansen, Thomas Folkmann, Jonsson, Anna Elisabet, Jorgensen, T., Liu, J., Møllehave, Line Tang, Smit, Roelof Adriaan Johan, Zhao, J., Bisgaard, H., Bønnelykke, Klaus, Dantoft, T. M., Grarup, Niels, Hansen, Torben, Jackson, R. D., Karpe, F., Kovacs, P., Lind, L., Linneberg, Allan René, Pedersen, Oluf Borbye, Werge, Thomas, Sun, Y., Loos, Ruth, Winkler, T. W., 23andMe Res Team, 2. R. T., VA Million Vet Program, V. M. V. P., DiscovEHR DiscovEHR MyCode Communi, D. D. M. C., eEMERGE Elect Med Records Genomics, E. E. M. R. G., LifeLines Cohort Study, L. C. S., PRACTICAL consortium, P. C. & Understanding Soc Sci Grp, U. S. S. G., 2022, In: Nature. 610, p. 704–712

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Associations of 25 Hydroxyvitamin D and High Sensitivity C-reactive Protein Levels in Early Life

    Brustad, N., Fink, N. R., Stokholm, Jakob, Bønnelykke, Klaus, Følsgaard, N. V., Hougaard, D., Brix, S., Lasky-Su, J., Weiss, S. T. & Chawes, Bo Lund Krogsgaard, 2022, In: Nutrients. 14, 1, 9 p., 15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Asthma and Wheeze Severity and the Oropharyngeal Microbiota in Children and Adolescents

    Thorsen, J., Stokholm, J., Rasmussen, M. A., Roggenbuck-Wedemeyer, M., Vissing, N. H., Mortensen, M. S., Brejnrod, A. D., Fleming, L., Bush, A., Roberts, G., Singer, F., Frey, U., Hedlin, G., Nordlund, B., Murray, C. S., Abdel-Aziz, M. I., Hashimoto, S., van Aalderen, W., Maitland-van der Zee, A. H., Shaw, D. & 13 others, Fowler, S. J., Sousa, A., Sterk, P. J., Chung, K. F., Adcock, I. M., Djukanovic, R., Auffray, C., Bansal, A. T., Wagers, S., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Sørensen, Søren Johannes & Bisgaard, H., 2022, In: Annals of the American Thoracic Society. 19, 12, p. 2031-2043 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Azithromycin and high-dose vitamin D for treatment and prevention of asthma-like episodes in hospitalised preschool children: Study protocol for a combined double-blind randomised controlled trial

    Kyvsgaard, J. N., Ralfkiaer, U., Følsgaard, N., Jensen, T. M., Hesselberg, L. M., Schoos, A. M., Bønnelykke, Klaus, Bisgaard, H., Stokholm, Jakob & Chawes, Bo Lund Krogsgaard, 2022, In: BMJ Open. 12, 4, 11 p., e054762.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Childhood asthma is associated with development of type 1 diabetes and inflammatory bowel diseases: a Danish nationwide registry study

    Liljendahl, M. S., Sevelsted, A., Chawes, Bo Lund Krogsgaard, Stokholm, J., Bønnelykke, Klaus, Andersen, Zorana Jovanovic & Bisgaard, H., 2022, In: Scientific Reports. 12, 1, 21728.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Early-life respiratory tract infections and the risk of school-age lower lung function and asthma: a meta-analysis of 150 000 European children

    van Meel, E. R., Mensink-Bout, S. M., den Dekker, H. T., Ahluwalia, T. S., Annesi-Maesano, I., Arshad, S. H., Baïz, N., Barros, H., von Berg, A., Bisgaard, H., Bønnelykke, K., Carlsson, C. J., Casas, M., Chatzi, L., Chevrier, C., Dalmeijer, G., Dezateux, C., Duchen, K., Eggesbø, M., van der Ent, C. & 31 others, Fantini, M., Flexeder, C., Frey, U., Forastiere, F., Gehring, U., Gori, D., Granell, R., Griffiths, L. J., Inskip, H., Jerzynska, J., Karvonen, A. M., Keil, T., Kelleher, C., Kogevinas, M., Koppen, G., Kuehni, C. E., Lambrechts, N., Lau, S., Lehmann, I., Ludvigsson, J., Magnus, M. C., Mélen, E., Mehegan, J., Mommers, M., Nybo Andersen, Anne-Marie, Nystad, W., Pedersen, E. S. L., Pekkanen, J., Peltola, V., Pinot de Moira, Angela & LifeCycle Project Group, L. P. G., 2022, In: The European respiratory journal. 60, 2, 65 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Effect of perfluoroalkyl exposure in pregnancy and infancy on intrauterine and childhood growth and anthropometry. Sub study from COPSAC2010 birth cohort

    Sevelsted, A., Gürdeniz, G., Rago, D., Pedersen, C. T., Lasky-Su, J. A., Checa, A., Zhang, P., Wheelock, C. E., Normann, S. S., Kristensen, D. M., Rasmussen, Morten Arendt, Schullehner, J., Sdougkou, K., Martin, J. W., Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, H. & Chawes, Bo Lund Krogsgaard, 2022, In: EBioMedicine. 83, 12 p., 104236.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Effects of prenatal nutrient supplementation and early life exposures on neurodevelopment at age 10: a randomised controlled trial - the COPSYCH study protocol

    Mohammadzadeh, P., Rosenberg, J. B., Vinding, R., Jepsen, J. R. M., Lindberg, U., Folsgaard, N., Sorensen, M. E., Sulaiman, D., Bilenberg, N., Raghava, J. M., Fagerlund, Birgitte, Vestergaard, M., Pantelis, C., Stokholm, Jakob, Chawes, Bo Lund Krogsgaard, Larsson, Henrik Bo Wiberg, Glenthøj, Birte Yding, Bønnelykke, Klaus, Ebdrup, Bjørn & Bisgaard, H., 2022, In: BMJ Open. 12, 2, 10 p., e047706.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Furan fatty acid metabolite in newborns predicts risk of asthma

    Gürdeniz, G., Kim, M., Brustad, N., Ernst, M., Russo, F., Stokholm, Jakob, Bønnelykke, Klaus, Hougaard, D., Rasmussen, M., Cohen, A. & Chawes, Bo Lund Krogsgaard, 2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 78, 2, p. 429-438 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes

    Vogelezang, S., Bradfield, J. P., Early Growth Genetics Consortium, Ahluwalia, T. V. S., Liu, X., Schnurr, T. M., Frithioff-Bøjsøe, C., Bønnelykke, K., Lind, M. V., Lauritzen, L., Michaelsen, K. F., Lund, M. A. V., Melbye, M., Morgen, C. S., Pedersen, O. B., Holm, J-C., Grarup, N., Hansen, T., Nohr, E. A., Bisgaard, H. & 3 others, Grant, S. F. A., Felix, J. F. & Jaddoe, V. W. V., 2022, In: BMC Medical Genomics. 15, 16 p., 124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB

    Eliasen, A. U., Pedersen, C. E. T., Rasmussen, M. A., Wang, N., Soverini, M., Fritz, A., Stokholm, J., Chawes, B. L., Morin, A., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Mortensen, P. B., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, M. & 14 others, Børglum, A. D., Werge, Thomas, Agerbo, E., Söderhall, C., Altman, M. C., Thysen, A. H., McKennan, C. G., Brix, Susanne, Gern, J. E., Ober, C., Ahluwalia, Tarun Veer Singh, Bisgaard, H., Pedersen, A. G. & Bønnelykke, Klaus, 2022, In: Journal of Allergy and Clinical Immunology. 150, 3, p. 622-630

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Height and bone mineral content after inhaled corticosteroid use in the first 6 years of life

    Kunøe, A., Sevelsted, A., Chawes, Bo Lund Krogsgaard, Stokholm, J., Krakauer, M., Bønnelykke, Klaus & Bisgaard, H., 2022, In: Thorax. 77, 8, p. 745-751 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    High-dose vitamin D supplementation in pregnancy and 25(OH)D sufficiency in childhood reduce the risk of fractures and improve bone mineralization in childhood: Follow-up of a randomized clinical trial

    Brustad, N., Chawes, Bo Lund Krogsgaard, Thorsen, Jonathan Jan Ilve, Krakauer, M., Lasky-Su, J., Weiss, S. T., Stokholm, J., Bønnelykke, Klaus & Bisgaard, H., 2022, In: EClinicalMedicine. 43, 10 p., 101254.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Increasing severity of early-onset atopic dermatitis, but not late-onset, associates with development of aeroallergen sensitization and allergic rhinitis in childhood

    Schoos, A. M. M., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Stokholm, Jakob, Rasmussen, Morten Arendt & Bisgaard, H., 2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 77, 4, p. 1254-1262

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Nasal DNA methylation at three CpG sites predicts childhood allergic disease

    van Breugel, M., Qi, C., Xu, Z., Pedersen, C. E. T., Petoukhov, I., Vonk, J. M., Gehring, U., Berg, M., Bügel, M., Carpaij, O. A., Forno, E., Morin, A., Eliasen, A. U., Jiang, Y., van den Berge, M., Nawijn, M. C., Li, Y., Chen, W., Bont, L. J., Bønnelykke, K. & 3 others, Celedón, J. C., Koppelman, G. H. & Xu, C. J., 2022, In: Nature Communications. 13, 7415.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Neonatal metabolome of caesarean section and risk of childhood asthma

    Gürdeniz, G., Ernst, M., Rago, D., Kim, M., Courraud, J., Stokholm, Jakob, Bønnelykke, Klaus, Björkbom, A., Trivedi, Urvish, Sørensen, Søren Johannes, Brix, Susanne, Hougaard, D., Rasmussen, Morten Arendt, Cohen, A. S., Bisgaard, H. & Chawes, Bo Lund Krogsgaard, 2022, In: The European Respiratory Journal. 59, 6, 11 p., 2102406.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Overvægtsrelateret astma hos børn og unge

    Horner, David Lyle George, Enevoldsen, J., Stokholm, Jakob, Bønnelykke, Klaus & Chawes, Bo Lund Krogsgaard, 2022, In: Ugeskrift for Laeger. 184, 42, 7 p., V03220205.

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation

    Mikus, M. S., Kolmert, J., Andersson, L. I., Östling, J., Knowles, R. G., Gómez, C., Ericsson, M., Thörngren, J. O., Khoonsari, P. E., Dahlén, B., Kupczyk, M., de Meulder, B., Auffray, C., Bakke, P. S., Beghe, B., Bel, E. H., Caruso, M., Chanez, P., Chawes, B., Fowler, S. J. & 32 others, Gaga, M., Geiser, T., Gjomarkaj, M., Horváth, I., Howarth, P. H., Johnston, S. L., Joos, G., Krug, N., Montuschi, P., Musial, J., Niżankowska-Mogilnicka, E., Olsson, H. K., Papi, A., Rabe, K. F., Sandström, T., Shaw, D. E., Siafakas, N. M., Uhlén, M., Riley, J. H., Bates, S., Middelveld, R. J. M., Wheelock, C. E., Chung, K. F., Adcock, I. M., Sterk, P. J., Bisgaard, H., Bønnelykke, Klaus, Vestbo, J., Vissing, N. H., Olsson, M., U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease outcome) Study Group, U. (. B. F. T. P. O. R. D. O. S. G. & BIOAIR (Longitudinal Assessment of Clinical Course and Biomarkers in Severe Chronic Airway Disease) Consortium, B. (. A. O. C. C. A. B. I. S. C. A. D. C., 2022, In: European Respiratory Journal. 59, 2, 17 p., 2100142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

    Okbay, A., Wu, Y., Wang, N., Jayashankar, H., Bennett, M., Nehzati, S. M., Sidorenko, J., Kweon, H., Goldman, G., Gjorgjieva, T., Jiang, Y., Hicks, B., Tian, C., Hinds, D. A., Ahlskog, R., Magnusson, P. K. E., Oskarsson, S., Hayward, C., Campbell, A., Porteous, D. J. & 31 others, Freese, J., Herd, P., Agee, M., Alipanahi, B., Auton, A., Bell, R. K., Bryc, K., Elson, S. L., Fontanillas, P., Furlotte, N. A., Hinds, D. A., Huber, K. E., Kleinman, A., Litterman, N. K., McCreight, J. C., McIntyre, M. H., Mountain, J. L., Northover, C. A. M., Pitts, S. J., Sathirapongsasuti, J. F., Sazonova, O. V., Shelton, J. F., Pers, Tune H, Timshel, P., Ahluwalia, Tarun Veer Singh, Bønnelykke, Klaus, Bisgaard, H., Sørensen, Thorkild I.A., 23andMe Research Team, 2. R. T., Social Science Genetic Association Consortium, S. S. G. A. C. & LifeLines Cohort Study, L. C. S., 2022, In: Nature Genetics. 54, 4, p. 437-449 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Prenatal tobacco exposure and risk of asthma and allergy outcomes in childhood

    Sunde, R. B., Thorsen, Jonathan Jan Ilve, Pedersen, C. T., Stokholm, J., Bønnelykke, Klaus, Chawes, Bo Lund Krogsgaard & Bisgaard, H., 2022, In: European Respiratory Journal. 59, 2, 2100453.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Reduced Steroid Metabolites Identify Infection-Prone Children in Two Independent Pre-Birth Cohorts

    Prince, N., Kim, M., Kelly, R. S., Diray-Arce, J., Bønnelykke, Klaus, Chawes, Bo Lund Krogsgaard, Huang, M., Levy, O., Litonjua, A. A., Stokholm, J., Wheelock, C. E., Bisgaard, H., Weiss, S. T. & Lasky-Su, J. A., 2022, In: Metabolites. 12, 11, p. 12 12 p., 1108.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Safety of High-Dose Vitamin D Supplementation among Children Aged 0 to 6 Years: A Systematic Review and Meta-analysis

    Brustad, N., Yousef, S., Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, H. & Chawes, Bo Lund Krogsgaard, 2022, In: JAMA network open. 5, 4, 14 p., E227410.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    The developing airway and gut microbiota in early life is influenced by age of older siblings

    Christensen, E. D., Hjelmsø, M. H., Thorsen, Jonathan Jan Ilve, Shah, S., Redgwell, T., Poulsen, Christina Egeø, Trivedi, Urvish, Russel, J., Gupta, S., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Sørensen, Søren Johannes, Rasmussen, Morten Arendt, Bisgaard, H. & Stokholm, Jakob, 2022, In: Microbiome. 10, 15 p., 106.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Vaginal dysbiosis in pregnancy associates with risk of emergency caesarean section: a prospective cohort study

    Haahr, T., Clausen, Tine Dalsgaard, Thorsen, J., Rasmussen, Morten Arendt, Mortensen, M. S., Lehtimäki, J., Shah, S. A., Hjelmsø, M. H., Bønnelykke, Klaus, Chawes, Bo Lund Krogsgaard, Vestergaard, G., Jacobsson, B., Larsson, P., Brix, S., Sørensen, Søren Johannes, Bisgaard, H. & Stokholm, Jakob, 2022, In: Clinical Microbiology and Infection. 28, 4, p. Pages 588-595

    Research output: Contribution to journalJournal articleResearchpeer-review

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