John Robert Couchman

John Robert Couchman

  • Nutritional Immunology

    BRIC, Ole Maaløes Vej 5, 2200 København N, Building: 1-4-28A

    Phone: +45 35 33 07 32
ORCID: 0000-0003-3409-7093

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  1. Published

    Syndecan-1 limits the progression of liver injury and promotes liver repair in acetaminophen-induced liver injury in mice

    Nam, E. J., Hayashida, K., Aquino, R. S., Couchman, John Robert, Kozar, R. A., Liu, J. & Park, P. W., 1 Nov 2017, In: Hepatology. 66, 5, p. 1601-1615 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Syndecan-4 proteoglycan regulates the distribution and activity of protein kinase C.

    Oh, E. S., Woods, A. & Couchman, John Robert, 1997, In: Journal of Biological Chemistry. 272, 13, p. 8133-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Multimerization of the cytoplasmic domain of syndecan-4 is required for its ability to activate protein kinase C.

    Oh, E. S., Woods, A. & Couchman, John Robert, 1997, In: Journal of Biological Chemistry. 272, 18, p. 11805-11 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Serine phosphorylation of syndecan-2 proteoglycan cytoplasmic domain.

    Oh, E. S., Couchman, John Robert & Woods, A., 1997, In: Archives of Biochemistry and Biophysics. 344, 1, p. 67-74 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Syndecan-4 proteoglycan cytoplasmic domain and phosphatidylinositol 4,5-bisphosphate coordinately regulate protein kinase C activity.

    Oh, E. S., Woods, A., Lim, S. T., Theibert, A. W. & Couchman, John Robert, 1998, In: Journal of Biological Chemistry. 273, 17, p. 10624-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Syndecans-2 and -4; close cousins, but not identical twins.

    Oh, E. & Couchman, John Robert, 2004, In: Molecules and Cells. 17, 2, p. 181-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Syndecan proteoglycan contributions to cytoskeletal organization and contractility

    Okina, E., Manon-Jensen, T., Whiteford, J. R. & Couchman, John Robert, 2009, In: Scandinavian Journal of Medicine & Science in Sports Online.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Alpha-actinin interactions with syndecan-4 are integral to fibroblast-matrix adhesion and regulate cytoskeletal architecture

    Okina, E., Grossi, A. B., Pakideeri Karat, S. G., Multhaupt, Hinke Arnolda B V H & Couchman, John Robert, 2012, In: International Journal of Biochemistry & Cell Biology. 44, 12, p. 2161-2174 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Cell-extracellular matrix and cell-cell adhesion are linked by syndecan-4

    Pakideeri Karat, S. G., Multhaupt, Hinke Arnolda B V H, Pocock, R. & Couchman, John Robert, Jul 2017, In: Matrix Biology. 60-61, p. 57-69 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Structure and function of syndecans

    Pataki, C. & Couchman, John Robert, 17 Aug 2012, Extracellular Matrix: Pathobiology and Signaling. Mouton de Gruyter, p. 197-208 12 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  11. Published

    Wnt Signaling Cascades and the Roles of Syndecan Proteoglycans

    Pataki, C. A., Couchman, John Robert & Brábek, J., 24 Apr 2015, In: Journal of Histochemistry and Cytochemistry. 63, 7, p. 465-80 16 p.

    Research output: Contribution to journal › Review › Research › peer-review

  12. Published

    An epidermal microRNA regulates neuronal migration through control of the cellular glycosylation state

    Pedersen, M. E., Snieckute, Goda, Kagias, K., Nehammer, C., Multhaupt, Hinke Arnolda B V H, Couchman, John Robert & Pocock, R., 20 Sep 2013, In: Science. 341, 6152, p. 1404-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Cell-substratum interactions in the adhesion and locomotion of fibroblasts.

    Rees, D. A., Couchman, John Robert, Smith, C. G., Woods, A. & Wilson, G., 1982, In: Philosophical Transactions of the Royal Society of London. Biological Sciences. 299, 1095, p. 169-76 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Conformations, interactions and functions of intrinsically disordered syndecans

    Ricard-Blum, S. & Couchman, John Robert, 2023, In: Biochemical Society Transactions. 51, 3, p. 1083-1096 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Targeting syndecan shedding in cancer

    Sanderson, R. D. & Couchman, John Robert, 17 Aug 2012, Extracellular Matrix: Pathobiology and Signaling. Mouton de Gruyter, p. 802-812 11 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  16. Published

    Immunohistochemical localization of chondroitin sulfate, chondroitin sulfate proteoglycan, heparan sulfate proteoglycan, entactin, and laminin in basement membranes of postnatal developing and adult rat lungs.

    Sannes, P. L., Burch, K. K., Khosla, J., McCarthy, K. J. & Couchman, John Robert, 1993, In: American Journal of Respiratory Cell and Molecular Biology. 8, 3, p. 245-51 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Solution structure of the dimeric cytoplasmic domain of syndecan-4.

    Shin, J., Lee, W., Lee, D., Koo, B. K., Han, I., Lim, Y., Woods, A., Couchman, John Robert & Oh, E. S., 2001, In: Biochemistry. 40, 29, p. 8471-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Heparan sulfate regulates ADAM12 through a molecular switch mechanism.

    Sørensen, H. P., Vives, R. R., Manetopoulos, C., Albrechtsen, Reidar, Lydolph, M. C., Jacobsen, J., Couchman, John Robert & Wewer, Ulla M., 2008, In: Journal of Biological Chemistry.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Localization of glycosaminoglycan substitution sites on domain V of mouse perlecan.

    Tapanadechopone, P., Hassell, J. R., Rigatti, B. & Couchman, John Robert, 1999, In: Biochemical and Biophysical Research Communications. 265, 3, p. 680-90 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Epidermal transformation leads to increased perlecan synthesis with heparin-binding-growth-factor affinity.

    Tapanadechopone, P., Tumova, S., Jiang, X. & Couchman, John Robert, 2001, In: Biochemical Journal. 355, Pt 2, p. 517-27 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Insights into the key roles of proteoglycans in breast cancer biology and translational medicine

    Theocharis, A. D., Skandalis, S. S., Neill, T., Multhaupt, Hinke Arnolda B V H, Hubo, M., Frey, H., Gopal, S., Gomes, A., Afratis, N., Lim, H. C., Couchman, John Robert, Filmus, J., Sanderson, R. D., Schaefer, L., Iozzo, R. V. & Karamanos, N. K., Apr 2015, In: BBA Reviews on Cancer. 1855, 2, p. 276–300 25 p.

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Hierarchy of ADAM12 binding to integrins in tumor cells.

    Thodeti, C. K., Fröhlich, C., Nielsen, C. K., Holck, P., Sundberg, C., Kveiborg, Marie, Mahalingam, Y., Albrechtsen, Reidar, Couchman, John Robert & Wewer, Ulla M., 2005, In: Experimental Cell Research. 309, 2, p. 438-50 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA.

    Thodeti, C. K., Albrechtsen, Reidar, Grauslund, M., Asmar, M., Larsson, C., Takada, Y., Mercurio, A. M., Couchman, John Robert & Wewer, Ulla M., 2002, In: Journal of Biological Chemistry. 278, 11, p. 9576-84 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Rat mesangial cells in vitro synthesize a spectrum of proteoglycan species including those of the basement membrane and interstitium.

    Thomas, G. J., Shewring, L., McCarthy, K. J., Couchman, John Robert, Mason, R. M. & Davies, M., 1995, In: Kidney International. 48, 4, p. 1278-89 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Heparan sulfate proteoglycans on the cell surface: versatile coordinators of cellular functions.

    Tumova, S., Woods, A. & Couchman, John Robert, 2000, In: International Journal of Biochemistry & Cell Biology. 32, 3, p. 269-88 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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