Jens Lykkesfeldt

Jens Lykkesfeldt

Professor

Member of:

  • Lifepharm

ORCID: 0000-0002-6514-8407

Publication year:
All
201 - 250 out of 270Page size: 50
  1. 2009
  2. Published

    Poor vitamin C status is associated with increased carotid intima-media thickness, decreased microvascular function, and delayed myocardial repolarization in young patients with type 1 diabetes

    Odermarsky, M., Lykkesfeldt, Jens & Liuba, P., 2009, In: American Journal of Clinical Nutrition. 90, 2, p. 447-452 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Role of marginal vitamin C deficiency in atherogenesis: In vivo models and clinical studies

    Frikke-Schmidt, H. R. & Lykkesfeldt, Jens, 2009, In: Basic & Clinical Pharmacology & Toxicology. 104, 6, p. 419-433 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Vitamin C deficiency in early postnatal life impairs spatial memory and reduces the number of hippocampal neurons in guinea pigs

    Tveden-Nyborg, Pernille, Jensen, Louise Kruse, Raida, Z., Villumsen, C. K., Larsen, J. O. & Lykkesfeldt, Jens, 2009, In: American Journal of Clinical Nutrition. 90, 3, p. 540-546 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2008
  6. Published

    Carotid Artery Intima-Media Thickness and Cutaneous Microvascular Function are Associated With Vitamin C Levels in Young Patients With Type 1 Diabetes

    Odermarsky, M., Lykkesfeldt, Jens & Liuba, P., 2008, Scientific Sessions 2008.

    Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research

  7. Published

    Does vitamin C matter? A quest for in vivo effects of vitamin C deficiency

    Lykkesfeldt, Jens, 2008, In: Free Radical Research. 42, S1, p. s23 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  8. Published

    Morphine reduces spinal c-fos expression dose-dependently during experimental laparotomy in pigs: a combined pharmacokinetic and surgical study

    Lykkegaard, K., Lykkesfeldt, Jens, Lauritzen, B. & Svendsen, O., 2008, In: Research in Veterinary Science. 84, 3, p. 457-464 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Utility of melatonin to treat surgical stress after major vascular surgery - a safety study

    Kücükakin, B., Lykkesfeldt, Jens, Nielsen, H. J., Reiter, R. J., Rosenberg, Jacob & Gögenur, Ismail, 2008, In: Journal of Pineal Research. 44, 4, p. 426-431 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2007
  11. Published

    Ascorbate and dehydroascorbic acid as reliable biomarkers of oxidative stress: analytical reproducibility and long-term stability of plasma samples subjected to acidic deproteinization

    Lykkesfeldt, Jens, 2007, In: Cancer Epidemiology, Biomarkers & Prevention. 16, 11, p. 2513-2516 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Malondialdehyde as biomarker of oxidative damage to lipids caused by smoking: invited critical review

    Lykkesfeldt, Jens, 2007, In: Clinica Chimica Acta. 380, 1-2, p. 50-58 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Oxidants and antioxidants in disease: oxidative stress in farm animals

    Lykkesfeldt, Jens & Svendsen, O., 2007, In: Veterinary Journal. 173, 3, p. 502-511 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Oxidative stress and damage in liver, but not in brain, of Fischer 344 rats subjected to dietary iron supplementation with lipid-soluble[(3,5,5-Trimethylhexanoyl)ferrocene]

    Lykkesfeldt, Jens, Morgan, E., Christen, S., Skovgaard, L. T. & Moos, T., 2007, In: Journal of Biochemical and Molecular Toxicology (Print Edition). 21, 3, p. 145-155 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Vitamin C deficiency in weanling guinea pigs: differential expression of oxidative stress and DNA repair in liver and brain

    Lykkesfeldt, Jens, Trueba, G. P., Poulsen, H. E. & Christen, S., 2007, In: British Journal of Nutrition. 98, 6, p. 1116-1119 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2006
  17. Published

    Pharmacokinetics of amoxicillin administered in drinking water to recently weaned 3- to 4-week-old pigs with diarrhea experimentally induced by Escherichia coli O149:F4

    Jensen, G. M., Lykkesfeldt, Jens, Frydendahl, K., Møller, K. & Svendsen, O., 2006, In: American Journal of Veterinary Research. 67, 4, p. 648-653 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Smoking depletes vitamin C: should smokers be recommended to take supplements?

    Lykkesfeldt, Jens, 2006, Cigarette smoke and oxidative stress. Halliwell, B. B. & Poulsen, H. E. (eds.). Berlin: Kluwer Academic Publishers, p. 236-258 23 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  19. 2005
  20. Published

    Age-dependent change in Vitamin C status: a phenomenon of matruration rather than of ageing

    Lykkesfeldt, Jens & Moos, T., 2005, In: Mechanisms of Ageing and Development. 126, 8, p. 892-898 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Effects of heparin-binding protein (CAP37/azurocidin) in a porcine model of Actinobacillus pleuropneumoniae-induced pneumonia

    Lauritzen, B., Lykkesfeldt, Jens, Djurup, R., Flodgaard, H. & Svendsen, O., 2005, In: Pharmacological Research. 51, 6, p. 509-514 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Electroencephalographic changes after pediatric cardiac surgery with cardiopulmonary bypass: is slow wave activity unfavorable?

    Schmitt, B., Finckh, B., Christen, S., Lykkesfeldt, Jens, Schmid, E. R., Bauersfeld, U., Critelli, H., Hajnal, B. L., Gessler, P. & Molinari, L., 2005, In: Pediatric Research. 58, 4, p. 771-778 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Evaluation of a single dose versus a divided dose regimen of amoxycillin in treatment of Actinobacillus pleuropneumoniae infection in pigs

    Lauritzen, B., Lykkesfeldt, Jens & Friis, C., 2005, In: Research in Veterinary Science. 79, 1, p. 61-67 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Oxidative stress precedes peak systemic inflammatory response in pediatric patients undergoing cardiopulmonary bypass operation

    Christen, S., Finckh, B., Lykkesfeldt, Jens, Gessler, P., Frese-Schaper, M., Nielsen, P., Schmid, E. R. & Schmitt, B., 2005, In: Free Radical Biology & Medicine. 38, 10, p. 1323-1332 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Vitamin C: as biomarker and treatment of oxidative stress caused by smoking : methodological and clinical studies

    Lykkesfeldt, Jens, 2005, Copenhagen: Center for Skov, Landskab og Planlægning/Københavns Universitet. 59 p.

    Research output: Book/Report › Doctoral thesis › Research

  26. 2004
  27. Published

    Clindamycin is neuroprotective in experimental Streptococcus pneumoniae meningitis compared with ceftriaxone

    Böttcher, T., Ren, H., Goiny, M., Gerber, J., Lykkesfeldt, Jens, Kuhnt, U., Lotz, M., Bunkowski, S., Werner, C., Schau, I., Spreer, A., Christen, S. & Nau, R., 2004, In: Journal of Neurochemistry. 91, 6, p. 1450-1460 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Long-term high copper intake: effects on indexes of copper status, antioxidant status, and immune function in young men 1-3

    Turnlund, J. R., Jacob, R. A., Keen, C. L., Strain, J. J., Kelly, D. S., Domek, J. M., Keyes, W. R., Ensunsa, J. L., Lykkesfeldt, Jens & Coulter, J., 2004, In: American Journal of Clinical Nutrition. 79, 6, p. 1037-1044 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Optimized treatment regimens for enrofloxacin in pigs limits selection for resistance in salmonella and coliforms

    Wiuff, C., Lykkesfeldt, Jens, Aarestrup, F. M. & Svendsen, O., 2004. 1 p.

    Research output: Contribution to conference › Paper › Research

  30. Published

    Pharmacokinetics of amoxicillin after oral administration in recently weaned piglets with experimentally induced Escherichia coli subtype O149:F4 diarrhea

    Jensen, G. M., Lykkesfeldt, Jens, Frydendahl, K., Møller, K. & Svendsen, O., 2004, In: American Journal of Veterinary Research. 65, p. 992-995 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Plasma malondialdehyde is induced by smoking: a study with balanced antioxidant profiles

    Lykkesfeldt, Jens, Viscovich, M. & Poulsen, H. E., 2004, In: British Journal of Nutrition. 92, 2, p. 203-206 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Vitamin C and oxidative damage to DNA: chapter 11

    Poulsen, Henrik Enghusen, Møller, P., Lykkesfeldt, Jens, Weimann, A. & Loft, S., 2004, Vitamin C. Asard, H., May, J. M. & Smirnoff, N. (eds.). Oxford: BIOS Scientific Publishers, p. 189-202 14 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  33. Published

    Vitamin C pharmacokinetics of plain and slow release formulations in smokers

    Viscovich, M., Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2004, In: Clinical Nutrition. 23, 5, p. 1043-1050 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Vitamin C supplementation decreases oxidative DNA damage in mononuclear bood cells of smokers

    Møller, P., Viscovich, M., Lykkesfeldt, Jens, Loft, S., Jensen, A. & Poulsen, H. E., 2004, In: European Journal of Nutrition. 43, p. 267-274 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. 2003
  36. Published

    Ascorbic acid recycling in human erythrocytes is induced by smoking in vivo

    Lykkesfeldt, Jens, Viscovich, M. & Poulsen, H. E., 2003, In: Free Radical Biology & Medicine. 11, 11, p. 1439-1447 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Effect of smoking on erythorbic acid pharmacokinetics

    Lykkesfeldt, Jens, Bolbjerg, M. L. & Poulsen, H. E., 2003, In: British Journal of Nutrition. 89, 5, p. 667-671 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Evaluation of a single dose versus a divided dose regimen of danofloxacin in treatment of Actinobacillus pleuropneumoniae infection in pigs

    Lauritzen, B., Lykkesfeldt, Jens & Friis, C., 2003, In: Research in Veterinary Science. 74, 3, p. 271-277 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Putative biomarkers for evaluating antibiotic treatment: an experimental model of porcine Actinobacillus pleuropneumoniae infection

    Lauritzen, B., Lykkesfeldt, Jens, Skaanild, M. T., Angen, Ø., Nielsen, Jens Peter & Friis, C., 2003, In: Research in Veterinary Science. 74, 3, p. 261-270 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The effects of oral and intramuscular administration and dose escalation of enrofloxacin on the selection of quinolone resistance among Salmonella and coliforms in pigs

    Wiuff, C., Lykkesfeldt, Jens, Svendsen, O. & Aarestrup, F. M., 2003, In: Research in Veterinary Science. 75, 3, p. 185-193 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. 2002
  42. Published

    Biomarkers in evaluation of antibiotic treatment: an experimental model of porcine Actinobacillus pleuropneumoniae infection

    Lauritzen, B., Lykkesfeldt, Jens, Angen, Ø., Nielsen, Jens Peter & Friis, C., 2002.

    Research output: Contribution to conference › Paper › Research

  43. Published

    Cerebral vasculature is the major target of oxidative protein alterations in bacterial meningitis

    Schaper, M., Gergely, S., Lykkesfeldt, Jens, Zbären, J., Leib, S. L., Täuber, M. G. & Christen, S., 2002, In: Journal of Neuropathology and Experimental Neurology. 61, 7, p. 605-613 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Distribution of enrofloxacin in intestinal tissue and contents of healthy pigs after oral and intramuscular administrations

    Wiuff, C., Lykkesfeldt, Jens, Aarestrup, F. M. & Svendsen, O., 2002, In: Journal of Veterinary Pharmacology and Therapeutics. 25, 5, p. 335-342 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Evaluation of a single dose and a split-dose regimen of danofloxacin against Actinobacillus pleuropneumoniae infection in pigs

    Lauritzen, B., Lykkesfeldt, Jens & Friis, C., 2002.

    Research output: Contribution to conference › Paper › Research

  46. Published

    Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress

    Hagen, T. M., Liu, J., Lykkesfeldt, Jens, Wehr, C. M., Ingersoll, R. T., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 2002, In: Proceedings of the National Academy of Science of the United States of America. 99, 4, p. 1870-1875 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Gamma-tocopherol supplementation inhibits protein nitration and ascorbate oxidation in rats with inflammation

    Jiang, Q., Lykkesfeldt, Jens, Shigenaga, M. K., Shigeno, E. T., Christen, S. & Ames, B. N., 2002, In: Free Radical Biology & Medicine. 33, 11, p. 1534-1542 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Increased oxidative damage in vitamin C deficiency is accompanied by induction of ascorbic acid recycling capacity in young but not mature guinea pigs

    Lykkesfeldt, Jens, 2002, In: Free Radical Research. 36, 5, p. 567-574 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Measurement of ascorbic acid and dehydroascorbic acid in biological samples

    Lykkesfeldt, Jens, 2002, Current protocols in toxicology. Maines, M., Costa, L. G., Hodson, E., Reed, D. J. & Sipes, I. G. (eds.). New York: Wiley, p. 7.6.1-7.6.15 15 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  50. 2001
  51. Published

    Determination of malondialdehyde as dithiobarbituric acid adduct in biological samples by HPLC with fluorescence detection: comparison with ultraviolet-visible spectrophotometry

    Lykkesfeldt, Jens, 2001, In: Clinical Chemistry. 47, 9, p. 1725-1727 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Determination of the disappearance rate of iodine-125 labelled oils from the injection site after intramuscular and subcutaneous administration to pigs

    Weng Larsen, S., Reinvar, E., Svendsen, O., Lykkesfeldt, Jens, Friis, G. J. & Larsen, C., 2001, In: Internation Journal of Pharmaceutics. 230, p. 67-75 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Oxidative stress in brain during experimental bacterial meningitis: differential effects of alpha-phenyl-tert-butyl nitrone and N-acetylcysteine treatment

    Christen, S., Schaper, M., Lykkesfeldt, Jens, Siegenthaler, C., Bifrare, Y., Banic, S. O., Leib, S. L. & Täuber, M. G., 2001, In: Free Radical Biology & Medicine. 31, 6, p. 754-762 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. 2000
  55. Published

    Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes

    Lykkesfeldt, Jens, Christen, S., Wallock, L. M., Chang, H. H., Jacob, R. A. & Ames, B. N., 2000, In: American Journal of Clinical Nutrition. 71, p. 530-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Biochemical markers as indicators of the efficiency of antibiotic treatment of Actinobacillus pleuropneumoniae infection in pigs

    Lauritsen, B., Lykkesfeldt, Jens, Angen, Ø. & Friis, C., 2000. 1 p.

    Research output: Contribution to conference › Paper › Research

  57. Published

    Determination of ascorbic acid and dehydroascorbic acid in biological samples by high-performance liquid chromatography using subtraction methods: reliable reduction with tris[2-carboxyethyl]phosphine hydrochloride

    Lykkesfeldt, Jens, 2000, In: Analytical Biochemistry. 282, p. 89-93 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Morphine concentration in plasma andcerebrospinal fluid in the anaesthetised pig after a single intravenous administration

    Lykkegaard, K., Lykkesfeldt, Jens & Svendsen, O., 2000. 1 p.

    Research output: Contribution to conference › Paper › Research

  59. Published

    On the possible connection between vitamin C, cardiovirus and guinea pig lameness

    Clausen, F. B., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2000, Ikke angivet. Laboratory Animals Ltd, p. 101-104 4 p.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

  60. 1999
  61. Published

    (R)-α-Lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate

    Hagen, T. M., Ingersoll, R. T., Lykkesfeldt, Jens, Liu, J., Wehr, C. M., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 16 Feb 1999, In: FASEB Journal. 13, 2, p. 411-418 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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