Jens Bukh

Jens Bukh

Professor

Member of:


    1. 2024
    2. Published

      Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice

      Brown, A. J., Won, J. J., Wolfisberg, R., Fahnøe, U., Catanzaro, N., West, A., Moreira, F. R., Nogueira Batista, M., Ferris, M. T., Linnertz, C. L., Leist, S. R., Nguyen, C., De La Cruz, G., Midkiff, B. R., Xia, Y., Evangelista, M. D., Montgomery, S. A., Billerbeck, E., Bukh, J., Scheel, T. K. H. & 2 others, Rice, C. M. & Sheahan, T. P., 2024, In: Hepatology. 79, 1, p. 183-197

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Neutralizing antibody and CD8+ T cell responses following BA.4/5 bivalent COVID-19 booster vaccination in adults with and without prior exposure to SARS-CoV-2

      Underwood, Alexander Paul James, Sølund, C., Jacobsen, K., Binderup, A., Fernandez-Antunez, C., Mikkelsen, L. S., Inekci, D., Villadsen, S. L., Castruita, J. A. S., Pinholt, M., Fahnøe, Ulrik, Ramirez, S., Brix, L., Weis, Nina & Bukh, Jens, 2024, In: Frontiers in Immunology. 15, 14 p., 1353353.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. 2023
    5. Published
    6. Published

      Challenge Inoculum for Hepatitis C Virus Controlled Human Infection Model

      Liang, T. J., Law, J. L. M., Pietschmann, T., Ray, S. C., Bukh, Jens, Bull, R., Chung, R. T., Tyrrell, D. L., Houghton, M. & Rice, C. M., 2023, In: Clinical Infectious Diseases. 77, p. S257-S261

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington's disease

      Mullari, M., Fossat, Nicolas Julien, Skotte, Niels Henning, Asenjo-Martinez, A., Humphreys, D. T., Bukh, Jens, Kirkeby, Agnete, Scheel, Troels Kasper Høyer & Nielsen, Michael Lund, 2023, In: Nature Communications. 14, 20 p., 4348.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Characterization of multi-DAA resistance using a novel hepatitis C virus genotype 3a infectious culture system

      Fernandez-Antunez, C., Wang, K., Fahnøe, Ulrik, Mikkelsen, L. S., Gottwein, Judith Margarete, Bukh, Jens & Ramirez Almeida, Santseharay, 2023, In: Hepatology. 78, 2, p. 621-636 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Differential activity of nucleotide analogs against tick-borne encephalitis and yellow fever viruses in human cell lines

      Binderup, A., Galli, Andrea, Fossat, Nicolas Julien, Fernandez-Antunez, C., Mikkelsen, L. S., Rivera, Lizandro, Scheel, Troels Kasper Høyer, Fahnøe, Ulrik, Bukh, Jens & Ramirez, S., 2023, In: Virology. 585, p. 179-185 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Durability and breadth of neutralisation following multiple antigen exposures to SARS-CoV-2 infection and/or COVID-19 vaccination

      Underwood, Alexander Paul James, Sølund, C., Fernandez-Antunez, C., Villadsen, S. L., Mikkelsen, L. S., Fahnøe, Ulrik, Bollerup, S., Winckelmann, Anni Assing, Schneider, Uffe Vest, Binderup, A., Vizgirda, G., Sørensen, A. L., Vinten, C. N., Dalegaard, M. I., Ramirez Almeida, Santseharay, Weis, Nina & Bukh, Jens, 2023, In: EBioMedicine. 89, 104475.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Effect of Glycan Shift on Antibodies against Hepatitis C Virus E2 412–425 Epitope Elicited by Chimeric sHBsAg-Based Virus-Like Particles

      Czarnota, A., Offersgaard, Anna Falden, Owsianka, A., Alzua, G. P., Bukh, Jens, Gottwein, Judith Margarete, Patel, A. H., Bienkowska-Szewczyk, K. & Grzyb, K., 2023, In: Microbiology Spectrum. 11, 2, 17 p., e0024523.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      First-in-human use of a modular capsid virus-like vaccine platform: An open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2

      Smit, M. J., Sander, A. F., Ariaans, M. B. P. A., Fougeroux, C., Heinzel, C., Fendel, R., Esen, M., Kremsner, P. G., Ter Heine, R., Wertheim, H. F., Idorn, M., Paludan, S. R., Underwood, A. P., Binderup, A., Ramirez, S., Bukh, J., Soegaard, M., Erdogan, S. M., Gustavsson, T., Clemmensen, S. & 14 others, Theander, Thor Grundtvig, Salanti, Ali, Hamborg, M., de Jongh, W. A., McCall, M. B. B., Nielsen, Morten Agertoug, Mordmüller, B. G., COUGH-1 trial study group, C. T. S. G., Dagil, Robert, Goksøyr, L., Hulen, T. M., Brygger, C. M. J., Khalifé, P. K. & Vidal-Calvo, E. E., 2023, In: The Lancet Microbe. 4, 3, p. e140-e148

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Full-length sequence analysis of hepatitis C virus genotype 3b strains and development of an in vivo infectious 3b cDNA clone

      Bajpai, P. S., Collignon, Laura Maria F, Sølund, C., Madsen, L. W., Christensen, P. B., Øvrehus, A., Weis, Nina, Holmbeck, Kenn, Fahnøe, Ulrik & Bukh, Jens, 2023, In: Journal of Virology. 97, 12, 23 p., 00925.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide

      Sherwood, A. V., Rivera-Rangel, L. R., Ryberg, L. A., Larsen, H. S., Anker, K. M., Costa, R., Vågbø, C. B., Jakljevič, E., Pham, L. V., Fernandez-Antunez, C., Indrisiunaite, G., Podolska-Charlery, A., Grothen, J. E. R., Langvad, N. W., Fossat, N., Offersgaard, A., Al-Chaer, A., Nielsen, L., Kuśnierczyk, A., Sølund, C. & 8 others, Weis, Nina, Gottwein, Judith Margarete, Holmbeck, Kenn, Bottaro, S., Ramirez Almeida, Santseharay, Bukh, Jens, Scheel, Troels Kasper Høyer & Vinther, Jeppe, 2023, In: Nature. 619, p. 811-818

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Hepatitis C virus alters the morphology and function of peroxisomes

      Martin de Fourchambault, E., Callens, N., Saliou, J. M., Fourcot, M., Delos, O., Barois, N., Thorel, Q., Ramirez Almeida, Santseharay, Bukh, Jens, Cocquerel, L., Bertrand-Michel, J., Marot, G., Sebti, Y., Dubuisson, J. & Rouillé, Y., 2023, In: Frontiers in Microbiology. 14, 1254728.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Identification of novel neutralizing determinants for protection against HCV

      Alzua, G. P., Pihl, A. F., Offersgaard, Anna Falden, Velázquez-Moctezuma, R., Duarte Hernandez, Carlos Rene, Augestad, Elias Honerød, Fahnøe, Ulrik, Mathiesen, C. K., Krarup, H., Law, M., Prentø, Jannick, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: Hepatology. 73, 3, p. 982-996

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Identification of the viral and cellular microRNA interactomes during SARS-CoV-2 infection

      Fossat, Nicolas Julien, Lundsgaard, Emma Alberte, Costa, Rui, Rivera, Lizandro, Nielsen, L., Mikkelsen, L. S., Ramirez Almeida, Santseharay, Bukh, Jens & Scheel, Troels Kasper Høyer, 2023, In: Cell Reports. 42, 4, 112282.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Inactivated genotype 1a, 2a and 3a HCV vaccine candidates induced broadly neutralising antibodies in mice

      Alzua, G. P., Pihl, A. F., Offersgaard, Anna Falden, Duarte Hernandez, Carlos Rene, Duan, Z., Feng, S., Fahnøe, Ulrik, Sølund, C., Weis, Nina, Law, M., Prentø, Jannick, Christensen, Jan Pravsgaard, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: Gut. 72, 3, p. 560-572

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Mechanisms and Consequences of Genetic Variation in Hepatitis C Virus (HCV)

      Galli, Andrea & Bukh, Jens, 2023, Viral Fitness and Evolution: Population Dynamics and Adaptive Mechanisms. Springer, p. 237-264 28 p. (Current Topics in Microbiology and Immunology, Vol. 439).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    20. Published

      Molecular Determinants of Mouse Adaptation of Rat Hepacivirus

      Wolfisberg, R., Holmbeck, Kenn, Billerbeck, E., Thorselius, Caroline Eva, Batista, M. N., Fahnøe, Ulrik, Lundsgaard, Emma Alberte, Kennedy, Matthew James, Nielsen, L., Rice, C. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 2023, In: Journal of Virology. 97, 4, 17 p., e0181222.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Pre-existing, treatment-specific resistance-associated substitutions in hepatitis C virus genotype 1 and 3 and viral RNA titers during treatment with direct-acting antivirals

      Sølund, C., Pedersen, M. S., Fahnøe, Ulrik, Filskov, J., Jenssen, H., Weis, Nina, Schønning, Kristian & Bukh, Jens, 2023, In: APMIS. 131, 8, p. 426-433

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Renaming of the genus Flavivirus to Orthoflavivirus and extension of binomial species names within the family Flaviviridae

      Postler, T. S., Beer, M., Blitvich, B. J., Bukh, Jens, de Lamballerie, X., Drexler, J. F., Imrie, A., Kapoor, A., Karganova, G. G., Lemey, P., Lohmann, V., Simmonds, P., Smith, D. B., Stapleton, J. T. & Kuhn, J. H., 2023, In: Archives of Virology. 168, 9, 224.

      Research output: Contribution to journalReviewResearchpeer-review

    23. Published

      SARS-CoV-2 spike HexaPro formulated in aluminium hydroxide and administered in an accelerated vaccination schedule partially protects Syrian Hamsters against viral challenge despite low neutralizing antibody responses

      Christensen, D., Polacek, C., Sheward, D. J., Hanke, L., McInerney, G., Murrell, B., Hartmann, Katrine Top, Jensen, Henrik Elvang, Zimmermann, J., Jungersen, G., Illigen, K. E., Isling, L. K., Fernandez-Antunez, C., Ramirez Almeida, Santseharay, Bukh, Jens & Pedersen, Gabriel Kristian, 2023, In: Frontiers in Immunology. 14, 941281.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      SARS-CoV-2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID-19 vaccination

      Castruita, J. A. S., Schneider, Uffe Vest, Mollerup, S., Leineweber, T. D., Weis, Nina, Bukh, Jens, Pedersen, M. S. & Westh, Henrik T., 2023, In: APMIS. 131, 3, p. 128-132 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published
    26. Published

      The Role of CTLA-4 in T Cell Exhaustion in Chronic Hepatitis B Virus Infection

      Apol, Á. D., Winckelmann, Anni Assing, Duus, R. B., Bukh, Jens & Weis, Nina, 2023, In: Viruses. 15, 5, 1141.

      Research output: Contribution to journalReviewResearchpeer-review

    27. Published

      Toward a vaccine against hepatitis C virus

      Offersgaard, Anna Falden, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: Science. 380, 6640, p. 37-38 2 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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    ID: 12437