Janine Erler

Janine Erler

Professor

ORCID: 0000-0001-8675-6527

Publication year:
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1 - 50 out of 102Page size: 50
  1. 2023
  2. Published

    FES null mice demonstrate a reduction in neutrophil dependent pancreatic cancer metastatic burden

    Strøbech, Jan Erik, Giuriatti, P., Stagaard, Rikke, De Sepulveda, P., Nielsen, S. R. & Erler, Janine, 2023, In: Frontiers in Oncology. 13, 8 p., 1096499.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. E-pub ahead of print

    Fibroblast-Derived Lysyl Oxidase Increases Oxidative Phosphorylation and Stemness in Cholangiocarcinoma

    Lewinska, M., Zhuravleva, E., Satriano, L., Martinez, M. B., Bhatt, D. K., Oliveira, D. V. N. P., Antoku, Y., Keggenhoff, F. L., Castven, D., Marquardt, J. U., Matter, M. S., Erler, J. T., Oliveira, R. C., Aldana, B. I., Al-Abdulla, R., Perugorria, M. J., Calvisi, D. F., Perez, L. A., Rodrigues, P. M., Labiano, I. & 2 others, Banales, J. M. & Andersen, Jesper Bøje, 2023, (E-pub ahead of print) In: Gastroenterology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Fibroblast-derived matrix models desmoplastic properties and forms a prognostic signature in cancer progression

    Rafaeva, Maria, Jensen, A. R. D., Horton, E. R., Zornhagen, Kamilla Westarp, Strøbech, Jan Erik, Fleischhauer, L., Mayorca Guiliani, Alejandro Enrique, Nielsen, S. R., Grønseth, D. S., Kuś, F., Schoof, E. M., Arnes Perez, Luis, Koch, M., Clausen-Schaumann, H., Izzi, V., Reuten, R. & Erler, Janine, 2023, In: Frontiers in Immunology. 14, 12 p., 1154528.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Tumor Angiocrine Signaling: Novel Targeting Opportunity in Cancer

    Oria, Victor Oginga & Erler, Janine, 2023, In: Cells. 12, 20, 14 p., 2510.

    Research output: Contribution to journal › Review › Research › peer-review

  6. 2022
  7. Published

    Extracting, quantifying, and comparing dynamical and biomechanical properties of living matter through single particle tracking

    Scott, S., Weiss, M., Selhuber-Unkel, C., Farhangibarooji, Younes, Sabri, A., Erler, Janine, Metzler, R. & Oddershede, L. B., 22 Dec 2022, In: Physical Chemistry Chemical Physics. 2023, 25, p. 1513-1537 26 p.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Filopodia rotate and coil by actively generating twist in their actin shaft

    Leijnse, Natascha, Farhangibarooji, Younes, Arastoo, M. R., Sonder, S. L., Verhagen, B., Wullkopf, L., Erler, Janine, Semsey, S., Nylandsted, J., Oddershede, L. B., Doostmohammadi, Amin & Bendix, Poul Martin, 28 Mar 2022, In: Nature Communications. 13, 1, 16 p., 1636.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Effects of acute exercise training on tumor outcomes in men with localized prostate cancer: A randomized controlled trial

    Djurhuus, S. S., Schauer, T., Simonsen, C., Toft, Birgitte Grønkær, Jensen, A. R. D., Erler, Janine, Røder, Andreas, Hojman, P., Brasso, K. & Christensen, J. F., 2022, In: Physiological Reports. 10, 19, e15408.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Fibrotic activity quantified in serum by measurements of type III collagen pro-peptides can be used for prognosis across different solid tumor types

    Willumsen, N., Jensen, C., Green, G., Nissen, N. I., Neely, J., Nelson, D. M., Pedersen, R. S., Frederiksen, P., Chen, I. M., Boisen, M. K., Johansen, A. Z., Madsen, D. H., Svane, I. M., Lipton, A., Leitzel, K., Ali, S. M., Erler, J. T., Hurkmans, D. P., Mathijssen, R. H. J., Aerts, J. & 5 others, Eslam, M., George, J., Christiansen, C., Bissel, M. J. & Karsdal, M. A., 2022, In: Cellular and Molecular Life Sciences. 79, 4, 11 p., 204.

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    Matritecture: Mapping the extracellular matrix architecture during health and disease

    Reuten, R., Mayorca Guiliani, Alejandro Enrique & Erler, Janine, 2022, In: Matrix Biology Plus. 14, 6 p., 100102.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Modeling Metastatic Colonization in a Decellularized Organ Scaffold-Based Perfusion Bioreactor

    Rafaeva, Maria, Horton, E. R., Jensen, A. R. D., Madsen, C. D., Reuten, R., Willacy, O., Brøchner, Christian Beltoft, Jensen, Thomas Hartvig Lindkær, Zornhagen, Kamilla Westarp, Crespo Bravo, Marina, Grønseth, D. S., Nielsen, S. R., Idorn, M., Straten, P. T., Rohrberg, K., Spanggaard, I., Højgaard, M., Lassen, Ulrik Niels, Erler, Janine & Mayorca Guiliani, Alejandro Enrique, 2022, In: Advanced Healthcare Materials. 11, 1, 2100684.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Neutrophil granulocytes influence on extracellular matrix in cancer progression

    Strøbech, Jan Erik, Giuriatti, P. & Erler, Janine, 2022, In: American Journal of Physiology: Cell Physiology. 323, 2, p. C486-C493 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Tipping the balance: New insights into stromal regulation of cancer

    Castro, Joana & Erler, Janine, 2022, In: Cancer Cell. 40, 12, p. 1467-1469 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  15. 2021
  16. Published

    Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade

    Nielsen, S. R., Strøbech, Jan Erik, Horton, E. R., Jackstadt, R., Laitala, A., Crespo Bravo, Marina, Maltese, G., Jensen, A. R. D., Reuten, R., Rafaeva, Maria, Karim, S. A., Hwang, C. I., Arnes Perez, Luis, Tuveson, D. A., Sansom, O. J., Morton, J. P. & Erler, Janine, Dec 2021, In: Nature Communications. 12, 1, p. 1-15 3414.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Deciphering the temporal heterogeneity of cancer-associated fibroblast subpopulations in breast cancer

    Venning, F. A., Zornhagen, Kamilla Westarp, Wullkopf, L., Sjölund, J., Rodriguez-Cupello, C., Kjellman, P., Morsing, M., Hajkarim, M. C., Won, K. J., Erler, Janine & Madsen, C. D., 20 May 2021, In: Journal of Experimental and Clinical Cancer Research. 40, 1, 175.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Basement membrane stiffness determines metastases formation

    Reuten, R., Zendehroud, S., Nicolau, M., Fleischhauer, L., Laitala, A., Kiderlen, S., Nikodemus, D., Wullkopf, L., Nielsen, S. R., Mcneilly, S., Prein, C., Rafaeva, M., Schoof, E. M., Furtwängler, B., Porse, B. T., Kim, H., Won, K. J., Sudhop, S., Zornhagen, K. W., Suhr, F. & 11 others, Maniati, E., Pearce, O. M. T., Koch, M., Oddershede, L. B., Van Agtmael, T., Madsen, C. D., Mayorca Guiliani, Alejandro Enrique, Bloch, W., Netz, R. R., Clausen-schaumann, H. & Erler, Janine, 2021, In: Nature Materials. 20, p. 892–903

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Decellularization of the Murine Cardiopulmonary Complex

    Mayorca Guiliani, Alejandro Enrique, Rafaeva, Maria, Willacy, O., Madsen, C. D., Reuten, R. & Erler, Janine, 2021, In: Journal of Visualized Experiments. 171, 10 p., e61854.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Fiber finding algorithm using stepwise tracing to identify biopolymer fibers in noisy 3D images

    Rossen, Ninna Struck, Kyrsting, A., Giaccia, A. J., Erler, Janine & Oddershede, L. B., 2021, In: Biophysical Journal. 120, 18, p. 3860-3868 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Organ-Specific, Fibroblast-Derived Matrix as a Tool for Studying Breast Cancer Metastasis

    Jensen, A. R. D., Horton, E. R., Blicher, L. H., Pietras, E. J., Steinhauer, C., Reuten, R., Schoof, E. M. & Erler, Janine, 2021, In: Cancers. 13, 13, 20 p., 3331.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Prognostic value of blood-based fibrosis biomarkers in patients with metastatic colorectal cancer receiving chemotherapy and bevacizumab

    Nissen, N. I., Kehlet, S., Boisen, M. K., Liljefors, M., Jensen, C., Johansen, A. Z., Johansen, Julia Sidenius, Erler, Janine, Karsdal, M., Mortensen, J. H., Høye, A. & Willumsen, N., 2021, In: Scientific Reports. 11, 865.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2020
  24. Published

    Framing cancer progression: influence of the organ‐ and tumour‐specific matrisome

    Rafaeva, Maria & Erler, Janine, 2020, In: The FEBS Journal. 287, 8, p. 1454-1477

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Prognostic value of blood-based fibrosis biomarkers in patients with metastatic colorectal cancer receiving chemotherapy and bevacizumab

    Nissen, N. I., Kehlet, S., Boisen, M. K., Liljefors, M., Jensen, C., Johansen, A. Z., Johansen, Julia Sidenius, Erler, Janine, Karsdal, M. A., Mortensen, J., Høye, A. & Willumsen, N., 2020, In: Annals of Oncology. 31, Suppl. 4, p. S290-S290 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  26. 2019
  27. Published

    Decellularization and antibody staining of mouse tissues to map native extracellular matrix structures in 3D

    Mayorca Guiliani, Alejandro Enrique, Willacy, O., Madsen, C. D., Rafaeva, Maria, Elisabeth Heumüller, S., Bock, F., Sengle, G., Koch, M., Imhof, T., Zaucke, F., Wagener, R., Sasaki, T., Erler, Janine & Reuten, R., 1 Dec 2019, In: Nature Protocols. 14, 12, p. 3395-3425 31 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Interplay between LOX enzymes and integrins in the tumor microenvironment

    Amendola, P. G., Reuten, R. & Erler, Janine, May 2019, In: Cancers. 11, 5, 17 p., 729.

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    Mesenchymal stromal cell activation by breast cancer secretomes in bioengineered 3D microenvironments

    Blache, U., Horton, E. R., Xia, T., Schoof, E. M., Blicher, L. H., Schönenberger, A., Snedeker, J. G., Martin, I., Erler, Janine & Ehrbar, M., 1 Jan 2019, In: Life Science Alliance. 2, 3, 15 p., e201900304.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2018
  31. Published

    Friction-limited cell motility in confluent monolayer tissue

    Christensen, A., West, A. V., Wullkopf, L., Erler, Janine, Oddershede, L. B. & Mathiesen, Joachim, 25 Jul 2018, In: Physical Biology. 15, 6, 11 p., 066004.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Established Models and New Paradigms for Hypoxia-Driven Cancer-Associated Bone Disease

    Cox, T. R., Erler, Janine & Rumney, R. M. H., 1 Feb 2018, In: Calcified Tissue International. 102, 2, p. 163-173 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    Cancer cells' ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential

    Wullkopf, L., West, A. K. V., Leijnse, Natascha, Cox, T. R., Madsen, C. D., Oddershede, L. B. & Erler, Janine, 2018, In: Molecular Biology of the Cell. 29, 20, p. 2378-2385 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Hypoxic signalling in tumour stroma

    Laitala, A. & Erler, Janine, 2018, In: Frontiers in Oncology. 8, p. 1-13 13 p., 189.

    Research output: Contribution to journal › Review › Research › peer-review

  35. Published

    Notch-inducing hydrogels reveal a perivascular switch of mesenchymal stem cell fate

    Blache, U., Vallmajo-Martin, Q., Horton, E. R., Guerrero, J., Djonov, V., Scherberich, A., Erler, Janine, Martin, I., Snedeker, J. G., Milleret, V. & Ehrbar, M., 2018, In: EMBO Reports. 19, 8, p. 1-14 14 p., e45964.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Proteomic Characterization of Caenorhabditis elegans Larval Development

    Xia, T., Horton, E. R., Salcini, Anna Elisabetta, Pocock, R., Cox, T. R. & Erler, Janine, 2018, In: Proteomics. 18, 2, p. 1-7 7 p., 1700238.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Tumor endothelial marker 8 promotes cancer progression and metastasis

    Høye, A. M., Tolstrup, S. D., Horton, E. R., Nicolau, Monica, Frost, H., Woo, J. H., Mauldin, J. P., Frankel, A. E., Cox, T. R. & Erler, Janine, 2018, In: OncoTarget. 9, 53, p. 30173-30188 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. 2017
  39. Published

    Perspective on the interpretation of research and translation to clinical care with therapy-associated metastatic breast cancer progression as an example

    on behalf of the Board of the Metastasis Research Society, O. B. O. T. B. O. T. M. R. S., 1 Dec 2017, In: Clinical and Experimental Metastasis. 34, 8, p. 443-447 5 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  40. Published

    Dynamic Rearrangement of Cell States Detected by Systematic Screening of Sequential Anticancer Treatments

    Koplev, S., Longden, J., Ferkinghoff-Borg, J., Blicher Bjerregård, M., Cox, T. R., Erler, Janine, Pedersen, J. T., Voellmy, F., Sommer, M. O. A. & Linding, R., 19 Sep 2017, In: Cell Reports. 20, 12, p. 2784-2791 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Nuclear expression of lysyl oxidase enzyme is an independent prognostic factor in rectal cancer patients

    Liu, N., Cox, T. R., Cui, W., Adell, G., Holmlund, B., Ping, J., Jarlsfelt, I., Erler, Janine & Sun, X., 1 Sep 2017, In: OncoTarget. 8, 36, p. 60015-60024

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix

    Mayorca Guiliani, Alejandro Enrique, Madsen, C. D., Cox, T. R., Horton, E. R., Venning, F. A. & Erler, Janine, Jul 2017, In: Nature Medicine. 23, 7, p. 890-898 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Pre-metastatic niches: Organ-specific homes for metastases

    Peinado, H., Zhang, H., Matei, I. R., Costa-Silva, B., Hoshino, A., Rodrigues, G., Psaila, B., Kaplan, R. N., Bromberg, J. F., Kang, Y., Bissell, M. J., Cox, T. R., Giaccia, A. J., Erler, Janine, Hiratsuka, S., Ghajar, C. M. & Lyden, D., 1 May 2017, In: Nature Reviews Cancer. 17, 5, p. 302-317 16 p.

    Research output: Contribution to journal › Review › Research › peer-review

  44. Published

    Dynamics of cancerous tissue correlates with invasiveness

    West, A. V., Wullkopf, L., Christensen, A., Leijnse, Natascha, Tarp, J. M., Mathiesen, Joachim, Erler, Janine & Oddershede, L. B., 6 Mar 2017, In: Scientific Reports. 7, 43800.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer

    Chang, J., Lucas, M. C., Leonte, L. E., Garcia-Montolio, M., Singh, L. B., Findlay, A. D., Deodhar, M., Foot, J. S., Jarolimek, W., Timpson, P., Erler, Janine & Cox, T. R., 10 Feb 2017, In: OncoTarget. 8, 16, p. 26066-26078 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Division Induced Dynamics in Non-Invasive and Invasive Breast Cancer

    West, A. V., Wullkopf, L., Christensen, A., Leijnse, Natascha, Tarp, J. M., Mathiesen, Joachim, Erler, Janine & Oddershede, L. B., 3 Feb 2017, In: Biophysical Journal. 112, 3, Supp. 1, p. 123A-123A

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Correlation of Ultrasound Shear Wave Elastography with Pathological Analysis in a Xenografic Tumour Model

    Elyas, E., Papaevangelou, E., Alles, E. J., Erler, Janine, Cox, T. R., Robinson, S. P. & Bamber, J. C., 2017, In: Scientific Reports. 7, 9 p., 165.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Multi-Channel Optical Coherence Elastography Using Relative and Absolute Shear-Wave Time of Flight

    Elyas, E., Grimwood, A., Erler, Janine, Robinson, S. P., Cox, T. R., Woods, D., Clowes, P., De Luca, R., Marinozzi, F., Fromageau, J. & Bamber, J. C., 2017, In: PLOS ONE. 12, 1, 18 p., e0169664.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Regulation of tumor progression and metastasis by bone marrow-derived microenvironments

    El Rayes, T., Gao, D., Altorki, N. K., Cox, T. R., Erler, Janine & Mittal, V., 2017, Biomarkers of the Tumor Microenvironment: Basic Studies and Practical Applications. Akslen, L. A. & Watnick, R. S. (eds.). Springer, p. 303-328 26 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  50. 2016
  51. Published

    The role of lysyl oxidase, the extracellular matrix and the pre-metastatic niche in bone metastasis

    Gartland, A., Erler, Janine & Cox, T. R., Sep 2016, In: Journal of Bone Oncology. 5, 3, p. 100-103 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Structural ECM components in the premetastatic and metastatic niche

    Høye, A. M. & Erler, Janine, 15 Jun 2016, In: A J P: Cell Physiology (Online). 310, 11, C955-67.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Comparison of (18)F-FET and (18)F-FLT small animal PET for the assessment of anti-VEGF treatment response in an orthotopic model of glioblastoma

    Nedergaard, M. K., Michaelsen, Signe Regner, Perryman, L., Erler, Janine, Poulsen, H. S., Stockhausen, M., Lassen, Ulrik Niels & Kjær, Andreas, Mar 2016, In: Nuclear Medicine and Biology. 43, 3, p. 198-205 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis

    Cox, T. R., Gartland, A. & Erler, Janine, 15 Jan 2016, In: Cancer Research. 76, 2, p. 188-92 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  55. Published

    Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction

    González-Santamaría, J., Villalba, M., Busnadiego, O., López-Olañeta, M. M., Sandoval, P., Snabel, J., López-Cabrera, M., Erler, Janine, Hanemaaijer, R., Lara-Pezzi, E. & Rodríguez-Pascual, F., 1 Jan 2016, In: Cardiovascular Research. 109, 1, p. 67-78 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Fibrosis and Cancer: Partners in Crime or Opposing Forces?

    Cox, T. R. & Erler, Janine, 2016, In: Trends in Cancer. 2, 6, p. 279-282 4 p.

    Research output: Contribution to journal › Review › Research › peer-review

  57. Published

    Quantification of Lung Metastases from In Vivo Mouse Models

    Chang, J. & Erler, Janine, 2016, Advances in Experimental Medicine and Biology: Tumor Microenvironment. Koumenis, C., Coussens, L. M., Giaccia, A. & Hammond, E. (eds.). Springer, Vol. 899. p. 245-51 7 p. (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  58. 2015
  59. Published

    Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling

    Creixell, P., Schoof, E. M., Simpson, C. D., Longden, J., Miller, C. J., Lou, H. J., Perryman, L., Cox, T. R., Zivanovic, N., Palmeri, A., Wesolowska-Andersen, A., Helmer-Citterich, M., Ferkinghoff-Borg, J., Itamochi, H., Bodenmiller, B., Erler, Janine, Turk, B. E. & Linding, R., 16 Sep 2015, In: Cell.

    Research output: Contribution to journal › Journal article › Research › peer-review

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