Icaro Ariel Simon
Postdoc
Molecular and Cellular Pharmacology
Jagtvej 160
2100 København Ø
- 2024
Pharmacological Characterization and Radiolabeling of VUF15485, a High-Affinity Small-Molecule Agonist for the Atypical Chemokine Receptor ACKR3
Zarca, A. M., Adlere, I., Viciano, C. P., Arimont-Segura, M., Meyrath, M., Simon, I. A., Bebelman, J. P., Laan, D., Custers, H. G. J., Janssen, E., Versteegh, K. L., Buzink, M. C. M. L., Nesheva, D. N., Bosma, R., de Esch, I. J. P., Vischer, H. F., Wijtmans, M., Szpakowska, M., Chevigné, A., Hoffmann, C. & 5 others, , 2024, In: Molecular Pharmacology. 105, 4, p. 301-312 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Ligand selectivity hotspots in serotonin GPCRs
Simon, Icaro A, Bjørn-Yoshimoto, Walden, Harpsøe, Kasper, Iliadis, S., Svensson, B., Jensen, Anders A. & Gloriam, David E., 2023, In: Trends in Pharmacological Sciences. 44, 12, p. 978-990Research output: Contribution to journal › Review › Research › peer-review
PSW-Designer: An Open-Source Computational Platform for the Design and Virtual Screening of Photopharmacological Ligands
Simon, Icaro A, Homan, E. J., Wijtmans, M., Sundström, M., Leurs, R., De Esch, I. J. P. & Zarzycka, B. A., 2023, In: Journal of Chemical Information and Modeling. 63, 21, p. 6696-6705 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure–Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT2A Receptor Agonists
Pottie, E., Poulie, C. B. M., Simon, Icaro A, Harpsøe, Kasper, D’Andrea, L., Komarov, I. V., Gloriam, David E., Jensen, Anders A., Kristensen, Jesper Langgaard & Stove, C. P., 2023, In: ACS Chemical Neuroscience. 14, 15, p. 2727–2742Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists
Poulie, C. B. M., Pottie, E., Simon, Icaro A, Harpsøe, Kasper, D'Andrea, L., Komarov, I. V., Gloriam, David E., Jensen, Anders A., Stove, C. P. & Kristensen, Jesper Langgaard, 2022, In: Journal of Medicinal Chemistry. 65, 18, p. 12031–12043Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors
Huang, S., Xu, P., Shen, D., Simon, Icaro A, Mao, C., Tan, Y., Zhang, H., Harpsøe, Kasper, Li, H., Zhang, Y., You, C., Yu, X., Jiang, Y., Zhang, Y., Gloriam, David E. & Xu, H. E., 2022, In: Molecular Cell. 82, 14, p. 2681-2695.e6 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Structural insights into the lipid and ligand regulation of serotonin receptors
Xu, P., Huang, S., Zhang, H., Mao, C., Zhou, X. E., Cheng, X., Simon, Icaro A, Shen, D., Yen, H., Robinson, C. V., Harpsøe, Kasper, Svensson, B., Guo, J., Jiang, H., Gloriam, David E., Melcher, K., Jiang, Y., Zhang, Y. & Xu, H. E., 2021, In: Nature. 592, p. 469-473Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
CuO Nanofibers Immobilized on Paraffin-Impregnated Graphite Electrode and its Application in the Amperometric Detection of Glucose
Simon, Icaro A, Medeiros, N. G., Garcia, K. C., Soares, R. M. D., Rosa, A. T. & Silva, J. A., Aug 2015, In: Journal of the Brazilian Chemical Society. 26, 8, p. 1710-1717Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
Electrochemical Behavior of Gold Nanoparticles Generated In Situ on 3-(1-Imidazolyl)propyl-silsesquioxane
Simon, Icaro A, Vacaro, B. B., Nunes, M. R., Benvenutti, E. V., Dias, S. L. P., Gushikem, Y. & Arguello, J., Nov 2013, In: Electroanalysis. 25, 11, p. 2501-2506Research output: Contribution to journal › Journal article › Research › peer-review
ID: 345280972
Most downloads
-
47
downloads
Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
20
downloads
Ligand selectivity hotspots in serotonin GPCRs
Research output: Contribution to journal › Review › Research › peer-review
Published -
18
downloads
Structure–Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT2A Receptor Agonists
Research output: Contribution to journal › Journal article › Research › peer-review
Published