Henriette Pilegaard

Henriette Pilegaard

Professor

ORCID: 0000-0002-1071-0327

Publication year:
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1 - 50 out of 186Page size: 50
  1. 2023
  2. Published

    Hepatic PGC-1α has minor regulatory effect on the liver transcriptome and metabolome during high fat high fructose diet and exercise training

    Rasmussen, M. K., Thøgersen, R., Horsbøl Lindholm, P., Bertram, H. C. & Pilegaard, Henriette, 2023, In: Gene. 851, 14 p., 147039.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Impact of Aging and Lifelong Exercise Training on Mitochondrial Function and Network Connectivity in Human Skeletal Muscle

    Jørgensen, Stine Ringholm, Gudiksen, Anders, Halling, Jens Frey, Qoqaj, A., Rasmussen, P. M., Prats Gavalda, Clara, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2023, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 78, 3, 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Muscle PGC-1α modulates hepatic mitophagy regulation during aging

    Christensen, N. M., Jørgensen, Stine Ringholm, Buch, B. T., Gudiksen, Anders, Halling, Jens Frey & Pilegaard, Henriette, 2023, In: Experimental Gerontology. 172, 9 p., 112046.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Redox state and altered pyruvate metabolism contribute to a dose-dependent metformin-induced lactate production of human myotubes

    Maurer, J., Zhao, X., Irmler, M., Gudiksen, Anders, Pilmark, N. S., Li, Q., Goj, T., Beckers, J., Hrabě De Angelis, M., Birkenfeld, A. L., Peter, A., Lehmann, R., Pilegaard, Henriette, Karstoft, Kristian, Xu, G. & Weigert, C., 2023, In: American Journal of Physiology: Cell Physiology. 325, 4, p. C1131-C1143 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    TBC1D4-S711 controls skeletal muscle insulin sensitization after exercise and contraction

    Kjøbsted, Rasmus, Kristensen, Jonas Møller, Eskesen, N. O., Kido, K., Fjorder, Klara, Damgaard, D. F., Larsen, Jeppe Kjærgaard, Andersen, Nicoline Resen, Birk, Jesper Bratz, Gudiksen, Anders, Treebak, Jonas Thue, Schjerling, Peter, Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2023, In: Diabetes. 72, 7, p. 857-871 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. 2022
  8. Published

    Ameliorating effects of lifelong physical activity on healthy aging and mitochondrial function in human white adipose tissue

    Gudiksen, Anders, Qoqaj, A., Jørgensen, Stine Ringholm, Wojtaszewski, Jørgen F P, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2022, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 77, 6, p. 1101-1111 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Beta2-agonist increases skeletal muscle interleukin 6 production and release in response to resistance exercise in men

    Hostrup, Morten, Knudsen, Jakob Grunnet, Maag Kristensen, C., Jessen, Søren Kaare, Pilegaard, Henriette & Bangsbo, Jens, 2022, In: Scandinavian Journal of Medicine & Science in Sports. 32, 7, p. 1099-1108 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    GDF15 is an exercise-induced hepatokine regulated by glucagon and insulin in humans

    Plomgaard, Peter Stendahl, Hansen, J. S., Townsend, L. K., Gudiksen, Anders, Secher, Niels H., Clemmesen, J. O., Støving, R. K., Goetze, Jens P. , Wright, D. C. & Pilegaard, Henriette, 2022, In: Frontiers in Endocrinology. 13, 1037948.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Skeletal muscle adaptations to exercise are not influenced by metformin treatment in humans: secondary analyses of 2 randomised, clinical trials

    Pilmark, N. S., Oberholzer, L., Halling, Jens Frey, Kristensen, Jonas Møller, Bønding, C. P., Elkjær, I., Lyngbæk, M., Elster, G., Siebenmann, C., Holm, N. F., Birk, Jesper Bratz, Larsen, E. L., Meinild-Lundby, A., Wojtaszewski, Jørgen F P, Pilegaard, Henriette, Poulsen, H., Pedersen, Bente Klarlund, Hansen, K. B. & Karstoft, Kristian, 2022, In: Applied Physiology, Nutrition and Metabolism. 47, 3, p. 309-320 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Targeted removal of mitochondrial DNA from mouse and human extrachromosomal circular DNA with CRISPR-Cas9

    Feng, Weijia, Arrey Tané, Gerard, Zole, Egija, Iv, W., Liang, Xue, Han, Peng, Mohiyuddin, M., Pilegaard, Henriette & Regenberg, Birgitte, 2022, In: Computational and Structural Biotechnology Journal. 20, p. 3059-3067 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Time-dependent regulation of hepatic cytochrome P450 mRNA in male liver-specific PGC-1α knockout mice

    Sundekilde, U. K., Kristensen, C. M., Olsen, M. A., Pilegaard, Henriette & Rasmussen, M. K., 2022, In: Toxicology. 469, 8 p., 153121.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2021
  15. Published

    High metabolic substrate load induces mitochondrial dysfunction in rat skeletal muscle microvascular endothelial cells

    Hansen, Camilla Collin, Olsen, K., Pilegaard, Henriette, Bangsbo, Jens, Gliemann, Lasse & Hellsten, Ylva, 2021, In: Physiological Reports. 9, 14, 17 p., e14855.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2020
  17. Published

    Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner

    Buch, B. T., Halling, Jens Frey, Jørgensen, Stine Ringholm, Gudiksen, Anders, Kjøbsted, Rasmus, Olsen, M. A., Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2020, In: F A S E B Journal. 34, 6, p. 8653-8670

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Effect of insulin on natriuretic peptide gene expression in porcine heart

    Terzic, D., Zois, N. E., Hunter, I., Christoffersen, Christina, Plomgaard, Peter Stendahl, Olsen, Lisbeth Høier, Jørgensen, Stine Ringholm, Pilegaard, Henriette & Goetze, Jens P. , 2020, In: Peptides. 131, 10 p., 170370.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Exercise: from physiology to bedside to physiology

    Han, J., Neufer, D. & Pilegaard, Henriette, 2020, In: Pflügers Archiv - European Journal of Physiology. 472, 2, p. 135

    Research output: Contribution to journal › Editorial › Research › peer-review

  20. Published

    Hepatic PGC-1α is not essential for fasting-induced cytochrome p450 regulation in mouse liver

    Thøgersen, R., Maag Kristensen, C., Olsen, M. A., Bertram, H. C., Pilegaard, Henriette & Rasmussen, M. K., 2020, In: Biochemical Pharmacology. 172, 7 p., 113736.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Impact of skeletal muscle IL-6 on subcutaneous and visceral adipose tissue metabolism immediately after high- and moderate-intensity exercises

    Bertholdt, L., Gudiksen, Anders, Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2020, In: Pflügers Archiv - European Journal of Physiology. 472, 2, p. 217-233 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Inducible deletion of skeletal muscle AMPKα 1 reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise

    Hingst, J. R., Kjøbsted, R., Birk, J. B., Jørgensen, N. O., Larsen, M. R., Kido, K., Larsen, J. K., Kjeldsen, S. A. S., Fentz, J., Frøsig, C., Holm, S., Fritzen, A. M., Dohlmann, T. L., Larsen, S., Foretz, M., Viollet, B., Schjerling, P., Overby, P., Halling, J. F., Pilegaard, H. & 2 others, Hellsten, Ylva & Wojtaszewski, Jørgen F P, 2020, In: Molecular Metabolism. 40, 17 p., 101028.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Insulin resistance induced by growth hormone is linked to lipolysis and associated with suppressed pyruvate dehydrogenase activity in skeletal muscle: a 2x2 factorial, randomised, crossover study in human individuals

    Hjelholt, A. J., Charidemou, E., Griffin, J. L., Pedersen, S. B., Gudiksen, Anders, Pilegaard, Henriette, Jessen, N., Møller, N. & Jørgensen, J. O. L., 2020, In: Diabetologia. 63, 12, p. 2641-2653 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    PGC-1α-mediated regulation of mitochondrial function and physiological implications

    Halling, Jens Frey & Pilegaard, Henriette, 2020, In: Applied Physiology, Nutrition and Metabolism. 45, 9, p. 927-936 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  25. 2019
  26. Published

    Exercise physiology: future opportunities and challenges

    Han, J., Neufer, D. & Pilegaard, Henriette, 2019, In: Pflügers Archiv - European Journal of Physiology. 471, 3, p. 381 1 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  27. Published

    Inclusion of sprints in moderate intensity continuous training leads to muscle oxidative adaptations in trained individuals

    Gunnarsson, T. G. P., Brandt, N., Fiorenza, Matteo, Hostrup, Morten, Pilegaard, Henriette & Bangsbo, Jens, 2019, In: Physiological Reports. 7, 4, 15 p., e13976.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle

    Sailani, M. R., Halling, Jens Frey, Møller, H. D., Lee, H., Plomgaard, Peter Stendahl, Pilegaard, Henriette, Snyder, M. P. & Regenberg, Birgitte, 2019, In: Scientific Reports. 9, p. 1-11 3272.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    PGC-1α regulates mitochondrial properties beyond biogenesis with aging and exercise training

    Halling, Jens Frey, Jessen, H., Nøhr-Meldgaard, J., Buch, B. T., Christensen, N. M., Gudiksen, Anders, Jørgensen, Stine Ringholm, Neufer, P. D., Prats Gavalda, Clara & Pilegaard, Henriette, 2019, In: American journal of physiology. Endocrinology and metabolism. 317, 3, p. E513-E525

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Redundancy in regulation of lipid accumulation in skeletal muscle during prolonged fasting in obese men

    Høgild, M. L., Gudiksen, Anders, Pilegaard, Henriette, Stødkilde-Jørgensen, H., Pedersen, S. B., Møller, N., Jørgensen, J. O. L. & Jessen, N., 2019, In: Physiological Reports. 7, 21, 15 p., e14285.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2018
  32. Published

    Circular DNA elements of chromosomal origin are common in healthy human somatic tissue

    Møller, H. D., Mohiyuddin, M., Prada Luengo, Inigo, Sailani, M. R., Halling, Jens Frey, Plomgaard, Peter Stendahl, Maretty, L., Hansen, Anders Johannes, Snyder, M. P., Pilegaard, Henriette, Lam, H. Y. K. & Regenberg, Birgitte, 1 Dec 2018, In: Nature Communications. 9, 12 p., 1069.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Training state and skeletal muscle autophagy in response to 36 h of fasting

    Dethlefsen, M. M., Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Bangsbo, Jens, van Hall, Gerrit, Plomgaard, Peter Stendahl & Pilegaard, Henriette, Nov 2018, In: Journal of Applied Physiology. 125, 5, p. 1609-1619 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Impact of β-adrenergic signaling in PGC-1α-mediated adaptations in mouse skeletal muscle

    Brandt, N., Nielsen, L., Buch, B. T., Gudiksen, Anders, Jørgensen, Stine Ringholm, Hellsten, Ylva, Bangsbo, Jens & Pilegaard, Henriette, 1 Jan 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E1-E20 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Beta2-adrenoceptor agonist salbutamol increases protein turnover rates and alters signalling in skeletal muscle after resistance exercise in young men

    Hostrup, Morten, Reitelseder, S., Jessen, Søren Kaare, Kalsen, A., Nyberg, M. P., Egelund, J., Kreiberg, M., Maag Kristensen, C., Thomassen, Martin, Pilegaard, Henriette, Backer, Vibeke, Jacobson, G. A., Holm, L. & Bangsbo, Jens, 2018, In: Journal of Physiology. 596, 17, p. 4121-4139 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Exercise and exercise training-induced increase in autophagy markers in human skeletal muscle

    Brandt, N., Gunnarsson, T. G. P., Bangsbo, Jens & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 7, 12 p., e13651.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Impact of fasting followed by short-term exposure to interleukin-6 on cytochrome P450 mRNA in mice

    Rasmussen, M. K., Bertholdt, L., Gudiksen, Anders, Pilegaard, Henriette & Knudsen, Jakob Grunnet, 2018, In: Toxicology Letters. 282, p. 93-99 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Impact of liver PGC-1α on exercise and exercise training-induced regulation of hepatic autophagy and mitophagy in mice on HFF

    Dethlefsen, M. M., Kristensen, C. M., Tondering, A. S., Lassen, S. B., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 13, p. 1-16 e13731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Impact of skeletal muscle IL-6 on regulation of liver and adipose tissue metabolism during fasting

    Bertholdt, L., Gudiksen, Anders, Jessen, H. & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 11, p. 1597-1613

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Impact of training state on fasting-induced regulation of adipose tissue metabolism in humans

    Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Villesen, I., Tybirk, J., van Hall, Gerrit, Bangsbo, Jens, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2018, In: Journal of Applied Physiology. 124, 3, p. 729-740 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Metabolic stress-dependent regulation of the mitochondrial biogenic molecular response to high-intensity exercise in human skeletal muscle

    Fiorenza, Matteo, Gunnarsson, T. P., Hostrup, Morten, Iaia, F. M., Schena, F., Pilegaard, Henriette & Bangsbo, Jens, 2018, In: Journal of Physiology. 596, 14, p. 2823-2840 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Muscle PGC-1α in exercise and fasting-induced regulation of hepatic UPR in mice

    Maag Kristensen, C., Jessen, H., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Acta Physiologica. 224, 4, p. 1-17 e13158.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    PGC-1α in exercise and fasting-induced regulation of hepatic UPR in mice

    Kristensen, C. M., Olsen, M. A., Jessen, H., Brandt, N., Meldgaard, J. N. & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 10, p. 1431-1447

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    PGC-1α in hepatic UPR during high-fat high-fructose diet and exercise training in mice

    Kristensen, C. M., Dethlefsen, M. M., Tøndering, A. S., Lassen, S. B., Meldgaard, J. N., Ringholm, S. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 15, p. 1-15 e13819.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training

    Dethlefsen, M. M., Halling, Jens Frey, Møller, H. D., Plomgaard, Peter Stendahl, Regenberg, Birgitte, Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Experimental Gerontology. 111, p. 141-153

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice

    Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, Ditte Olsen, Halling, Jens Frey, Hansen, M., Al-Soud, W. A., Hansen, Lars Hestbjerg, Kiilerich, P. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Training state and fasting-induced PDH regulation in human skeletal muscle

    Gudiksen, Anders, Bertholdt, L., Stankiewicz, T., Villesen, I., Bangsbo, Jens, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 11, p. 1633-1645 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. 2017
  49. Published

    Skeletal muscle IL-6 regulates muscle substrate utilization and adipose tissue metabolism during recovery from an acute bout of exercise

    Knudsen, Jakob Grunnet, Gudiksen, Anders, Bertholdt, L., Overby, P., Villesen, I., Schwartz, C. L. & Pilegaard, Henriette, 18 Dec 2017, In: PLoS ONE. 12, 12, 19 p., e0189301.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    PGC-1α in aging and lifelong exercise training-mediated regulation of UPR in mouse liver

    Maag Kristensen, C., Brandt, C. T., Jørgensen, Stine Ringholm & Pilegaard, Henriette, Nov 2017, In: Experimental Gerontology. 98, p. 124-133 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Exercise training protects against aging-induced mitochondrial fragmentation in mouse skeletal muscle in a PGC-1α dependent manner

    Halling, Jens Frey, Jørgensen, Stine Ringholm, Olesen, J., Prats Gavalda, Clara & Pilegaard, Henriette, 1 Oct 2017, In: Experimental Gerontology. 96, p. 1-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Autophagy-dependent beneficial effects of exercise

    Halling, Jens Frey & Pilegaard, Henriette, Aug 2017, In: Cold Spring Harbor Perspectives in Medicine. 7, 8, a029777.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    PGC-1α and fasting-induced PDH regulation in mouse skeletal muscle

    Gudiksen, Anders & Pilegaard, Henriette, 10 Apr 2017, In: Physiological Reports. 5, 7, 15 p., e13222.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Lack of skeletal muscle IL-6 influences hepatic glucose metabolism in mice during prolonged exercise

    Bertholdt, L., Gudiksen, Anders, Schwartz, C. L., Knudsen, Jakob Grunnet & Pilegaard, Henriette, 7 Apr 2017, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 312, 4, p. R626-R636 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Muscle interleukin-6 and fasting-induced PDH regulation in mouse skeletal muscle

    Gudiksen, Anders, Bertholdt, L., Vingborg, M. B., Hansen, H. W., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2 Mar 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 312, 3, p. E204-E214 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Effects of training status on PDH regulation in human skeletal muscle during exercise

    Gudiksen, Anders, Bertholdt, L., Stankiewicz, T., Tybirk, J., Plomgaard, Peter Stendahl, Bangsbo, Jens & Pilegaard, Henriette, 2017, In: Pflügers Archiv - European Journal of Physiology. 469, 12, p. 1615-1630 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Opposite regulation of insulin sensitivity by dietary lipid versus carbohydrate excess

    Lundsgaard, Anne-Marie, Sjøberg, K. A., Høeg, L. D., Jeppesen, J., Jordy, A. B., Serup, A. K. L., Fritzen, Andreas Mæchel, Pilegaard, Henriette, Myrmel, L. S., Madsen, L., Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2017, In: Diabetes. 66, 10, p. 2583-2595 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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