Henriette Pilegaard

Henriette Pilegaard

Professor

ORCID: 0000-0002-1071-0327

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  1. Published

    lactate transport studied in sarcolemmal giant vesicles from rats: effect og training

    Pilegaard, Henriette, Juel, C. & Wibrand, F., 1993, In: Am. J. Physiol.. 264, 2, p. E156-E160

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Vascular endothelial growth factor mRNA expression and arteriovenous balance in resonse to prolonged, submaximal exercise in humans

    Hiscock, N., Fischer, C. P., Pilegaard, Henriette & Pedersen, B. K., 2003, In: Am J Physiol - Heart Circ Physiol. 285, p. H1759-H1763

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Transgenic mice with astrocyte-targeted production of interleukin-6 are resistant to high-fat diet-induced increases in body weight and body fat

    Hidalgo, J., Florit, S., Giralt, M., Ferrer, B., Keller, C. & Pilegaard, Henriette, 2010, In: Brain, Behavior, and Immunity. 24, 1, p. 119-26 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Transcriptional regulation of pyruvate dehydrogenase kinase 4 in skeletal muscle during and after exercise

    Pilegaard, Henriette & Neufer, P. D., 2004, In: roceedings of the Nutrition Society. 63, p. 221-226

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise

    Pilegaard, Henriette, Ordway, G. A., Saltin, B. & Neufer, P. D., 2000, In: American Journal of Physiology: Endocrinology and Metabolism. 279, p. E806-E814

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Training state and skeletal muscle autophagy in response to 36 h of fasting

    Dethlefsen, M. M., Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Bangsbo, Jens, van Hall, Gerrit, Plomgaard, Peter Stendahl & Pilegaard, Henriette, Nov 2018, In: Journal of Applied Physiology. 125, 5, p. 1609-1619 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Training state and fasting-induced PDH regulation in human skeletal muscle

    Gudiksen, Anders, Bertholdt, L., Stankiewicz, T., Villesen, I., Bangsbo, Jens, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 11, p. 1633-1645 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Time-dependent regulation of hepatic cytochrome P450 mRNA in male liver-specific PGC-1α knockout mice

    Sundekilde, U. K., Kristensen, C. M., Olsen, M. A., Pilegaard, Henriette & Rasmussen, M. K., 2022, In: Toxicology. 469, 8 p., 153121.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The role of PGC-1alpha on mitochondrial function and apoptotic susceptibility in muscle

    Adhihetty, P. J., Uguccioni, G., Leick, L., Hidalgo, J., Pilegaard, Henriette & Hood, D. A., 2009, In: American Journal of Physiology: Cell Physiology. 297, 1, p. C217-25

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The mRNA expression profile of metabolic genes relative to MHC isoform pattern in human skeletal muscles

    Plomgaard, Peter Stendahl, Penkowa, M., Leick, L., Pedersen, Bente Klarlund, Saltin, B. & Pilegaard, Henriette, 2006, In: Journal of Applied Physiology. 101, 3, p. 817-25 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice

    Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, Ditte Olsen, Halling, Jens Frey, Hansen, M., Al-Soud, W. A., Hansen, Lars Hestbjerg, Kiilerich, P. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The contraction induced increase in gene expression of peroxisome proliferator-activated receptor (PPAR)-gamma coactivator 1alpha (PGC-1alpha), mitochondrial uncoupling protein 3 (UCP3) and hexokinase II (HKII) in primary rat skeletal muscle cells is dependent on reactive oxygen species

    Silveira, L. R., Pilegaard, Henriette, Kusuhara, K., Curi, R. & Hellsten, Ylva, 2006, In: BBA General Subjects. 1763, 9, p. 969-976

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Targeted removal of mitochondrial DNA from mouse and human extrachromosomal circular DNA with CRISPR-Cas9

    Feng, Weijia, Arrey Tané, Gerard, Zole, Egija, Iv, W., Liang, Xue, Han, Peng, Mohiyuddin, M., Pilegaard, Henriette & Regenberg, Birgitte, 2022, In: Computational and Structural Biotechnology Journal. 20, p. 3059-3067 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    TBC1D4-S711 controls skeletal muscle insulin sensitization after exercise and contraction

    Kjøbsted, Rasmus, Kristensen, Jonas Møller, Eskesen, N. O., Kido, K., Fjorder, Klara, Damgaard, D. F., Larsen, Jeppe Kjærgaard, Andersen, Nicoline Resen, Birk, Jesper Bratz, Gudiksen, Anders, Treebak, Jonas Thue, Schjerling, Peter, Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2023, In: Diabetes. 72, 7, p. 857-871 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Sucrose counteracts the anti-inflammatory effect of fish oil in adipose tissue and increases obesity development in mice

    Ma, Tao, Liaset, B., Hao, Q., Petersen, R. K., Fjære, E., Ngo, H. T., Lillefosse, H. H., Jørgensen, Stine Ringholm, Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Frøyland, L., Kristiansen, Karsten & Madsen, L., 2011, In: P L o S One. 6, 6, 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise

    Pilegaard, Henriette, Osada, T., nzt356, nzt356, Helge, Jørn Wulff, Saltin, B. & Neufer, P. D., 2005, In: Metabolism - Clinical and Experimental. 54, 8, p. 1048-55

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Subcellular localization and mechanism of secretion of vascular endothelial growth factor in human skeletal muscle

    Høier, B., Prats Gavalda, Clara, Qvortrup, Klaus, Pilegaard, Henriette, Bangsbo, Jens & Hellsten, Ylva, 2013, In: F A S E B Journal. 27, 9, p. 3496-3504 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Strong iron demand during hypoxia-induced erythropoiesis is associated with down-regulation of iron-related proteins and myoglobin in human skeletal muscle

    Robach, P., Cairo, G., Gelfi, C., Bernuzzi, F., Pilegaard, Henriette, Viganò, A., Santambrogio, P., Cerretelli, P., Calbet, J. A. L., Moutereau, S. & Lundby, C., 2007, In: Blood. 109, 11, p. 4724-31 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Skeletal muscle interleukin-6 regulates metabolic factors in iWAT during HFD and exercise training

    Knudsen, Jakob Grunnet, Bertholdt, L., Joensen, E., Lassen, S. B., Hidalgo, J. & Pilegaard, Henriette, 2015, In: Obesity. 23, 8, p. 1616-1624 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Skeletal muscle adaptations to exercise are not influenced by metformin treatment in humans: secondary analyses of 2 randomised, clinical trials

    Pilmark, N. S., Oberholzer, L., Halling, Jens Frey, Kristensen, Jonas Møller, Bønding, C. P., Elkjær, I., Lyngbæk, M., Elster, G., Siebenmann, C., Holm, N. F., Birk, Jesper Bratz, Larsen, E. L., Meinild-Lundby, A., Wojtaszewski, Jørgen F P, Pilegaard, Henriette, Poulsen, H., Pedersen, Bente Klarlund, Hansen, K. B. & Karstoft, Kristian, 2022, In: Applied Physiology, Nutrition and Metabolism. 47, 3, p. 309-320 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Skeletal muscle PGC-1a is required for maintaining an acute LPS-induced TNFa response

    Olesen, J., Larsson, S., Iversen, N., Yousafzai, S., Hellsten, Ylva & Pilegaard, Henriette, 2012, In: P L o S One. 7, 2, p. e32222 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Skeletal muscle IL-6 regulates muscle substrate utilization and adipose tissue metabolism during recovery from an acute bout of exercise

    Knudsen, Jakob Grunnet, Gudiksen, Anders, Bertholdt, L., Overby, P., Villesen, I., Schwartz, C. L. & Pilegaard, Henriette, 18 Dec 2017, In: PLoS ONE. 12, 12, 19 p., e0189301.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Skeletal muscle IL-6 and regulation of liver metabolism during high-fat diet and exercise training

    Knudsen, Jakob Grunnet, Joensen, E., Bertholdt, L., Jessen, H., van Hauen, L., Hidalgo, J. & Pilegaard, Henriette, 2016, In: Physiological Reports. 4, 9, 9 p., e12788.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Role of vitamin C and E supplementation on IL-6 in response to training

    Yfanti, C., Fischer, C. P., Nielsen, S., Åkerström, T., Nielsen, A. R., Veskoukis, A. S., Kouretas, D., Lykkesfeldt, Jens, Pilegaard, Henriette & Pedersen, Bente Klarlund, 2012, In: Journal of Applied Physiology. 112, 6, p. 990-1000 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Role of PGC-1α in exercise training- and resveratrol-induced prevention of age-associated inflammation

    Olesen, J., Jørgensen, Stine Ringholm, Nielsen, M. M., Brandt, C. T., Pedersen, J. T., Halling, J. F., Goodyear, L. J. & Pilegaard, Henriette, 2013, In: Experimental Gerontology. 48, 11, p. 1274-1284 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Role of PGC-1{alpha} in exercise and fasting induced adaptations in mouse liver

    Haase, T. N., Jørgensen, S. R., Leick, L., Biensø, R. S., Kiilerich, K., Johansen, S., Nielsen, M. M., Wojtaszewski, Jørgen F P, Hidalgo, J., Pedersen, Per Amstrup & Pilegaard, Henriette, 2011, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 301, 5, p. R1501-R1509 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Role of IL-6 in exercise training- and cold-induced UCP1 expression in subcutaneous white adipose tissue

    Knudsen, Jakob Grunnet, Murholm, M., Carey, A. L., Biensø, R. S., Basse, A. L., Allen, T. L., Hidalgo, J., Kingwell, B. A., Febbraio, M. A., Hansen, Jacob B. & Pilegaard, Henriette, 2014, In: P L o S One. 9, 1, 8 p., e84910.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men

    Gliemann, Lasse, Schmidt, J. F., Olesen, J., Biensø, R. S., Peronard, S. L., Grandjean, S. U., Mortensen, S. P., Nyberg, M. P., Bangsbo, Jens, Pilegaard, Henriette & Hellsten, Ylva, 2013, In: Journal of Physiology. 591, 20, p. 5047-5059 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Resistance exercise alters MRF and IGT-I mRNA content in human skeletal muscle

    Psilander, N., Damsgaard, R. & Pilegaard, Henriette, 2003, In: Journal of Applied Physiology. 95, p. 1038-1044

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Reply from Lasse Gliemann, Jesper Olesen, Rasmus Sjørup Biensø, Stefan Peter Mortensen, Michael Nyberg, Jens Bangsbo, Henriette Pilegaard and Ylva Hellsten

    Gliemann, Lasse, Olesen, J., Biensø, R. S., Mortensen, S. P., Nyberg, M. P., Schmidt, J. F., Bangsbo, Jens, Pilegaard, Henriette & Hellsten, Ylva, 2014, In: Journal of Physiology. 592, 3, p. 553 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  31. Published

    Reply from Lasse Gliemann, Jakob Schmidt, Jesper Olesen, Rasmus Sjørup Biensø, Sebastian Louis Peronard, Simon Udsen Grandjean, Stefan Peter Mortensen, Michael Nyberg, Jens Bangsbo, Henriette Pilegaard and Ylva Hellsten

    Gliemann, Lasse, Schmidt, J., Olesen, J., Biensø, R. S., Peronard, S. L., Grandjean, S. U., Mortensen, S. P., Nyberg, M., Bangsbo, Jens, Pilegaard, Henriette & Hellsten, Ylva, 2013, In: Journal of Physiology. 591, 20, p. 5253 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  32. Published

    Relative workload determines exercise-induced increases in PGC-1alpha mRNA

    Nordsborg, Nikolai Baastrup, Lundby, C., Leick, L. & Pilegaard, Henriette, 2010, In: Medicine and Science in Sports and Exercise. 42, 8, p. 1477-1484 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training

    Dethlefsen, M. M., Halling, Jens Frey, Møller, H. D., Plomgaard, Peter Stendahl, Regenberg, Birgitte, Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Experimental Gerontology. 111, p. 141-153

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Regulation of PDH in human arm and leg muscles at rest and during intense exercise

    Kiilerich, K., Birk, Jesper Bratz, Damsgaard, R., Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2008, In: American Journal of Physiology: Endocrinology and Metabolism. 294, 1, p. E36-E42 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Regular endurance training reduces the exercise induced HIF-1alpha and HIF-2alpha mRNA expression in human skeletal muscle in normoxic conditions

    Lundby, C., Gassmann, M. & Pilegaard, Henriette, 2005, In: European Journal of Applied Physiology. 96, 4, p. 363-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Redundancy in regulation of lipid accumulation in skeletal muscle during prolonged fasting in obese men

    Høgild, M. L., Gudiksen, Anders, Pilegaard, Henriette, Stødkilde-Jørgensen, H., Pedersen, S. B., Møller, N., Jørgensen, J. O. L. & Jessen, N., 2019, In: Physiological Reports. 7, 21, 15 p., e14285.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Redox state and altered pyruvate metabolism contribute to a dose-dependent metformin-induced lactate production of human myotubes

    Maurer, J., Zhao, X., Irmler, M., Gudiksen, Anders, Pilmark, N. S., Li, Q., Goj, T., Beckers, J., Hrabě De Angelis, M., Birkenfeld, A. L., Peter, A., Lehmann, R., Pilegaard, Henriette, Karstoft, Kristian, Xu, G. & Weigert, C., 2023, In: American Journal of Physiology: Cell Physiology. 325, 4, p. C1131-C1143 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle

    Treebak, Jonas Thue, Frøsig, C., Pehmøller, C., Chen, S., Maarbjerg, S. J., Brandt, N., Mackintosh, C., Zierath, J. R., Hardie, D. G., Kiens, Bente, Richter, Erik A., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2009, In: Diabetologia. 52, 5, p. 891-900 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    PGC-1α-mediated regulation of mitochondrial function and physiological implications

    Halling, Jens Frey & Pilegaard, Henriette, 2020, In: Applied Physiology, Nutrition and Metabolism. 45, 9, p. 927-936 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    PGC-1α-mediated adaptations in skeletal muscle

    Olesen, J., Kiilerich, K. & Pilegaard, Henriette, 2010, In: Pflügers Archiv - European Journal of Physiology. 460, 1, p. 153-162 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    PGC-1α regulates mitochondrial properties beyond biogenesis with aging and exercise training

    Halling, Jens Frey, Jessen, H., Nøhr-Meldgaard, J., Buch, B. T., Christensen, N. M., Gudiksen, Anders, Jørgensen, Stine Ringholm, Neufer, P. D., Prats Gavalda, Clara & Pilegaard, Henriette, 2019, In: American journal of physiology. Endocrinology and metabolism. 317, 3, p. E513-E525

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    PGC-1α promotes exercise-induced autophagy in mouse skeletal muscle

    Halling, Jens Frey, Jørgensen, Stine Ringholm, Nielsen, M. M., Overby, P. & Pilegaard, Henriette, 2016, In: Physiological Reports. 4, 3, 11 p., e12698.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    PGC-1α is required for AICAR induced expression of GLUT4 and mitochondrial proteins in mouse skeletal muscle

    Leick, L., Fentz, J., Biensø, R. S., Knudsen, Jakob Grunnet, Jeppesen, J., Kiens, Bente, Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 3, p. E456-E465 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    PGC-1α in hepatic UPR during high-fat high-fructose diet and exercise training in mice

    Kristensen, C. M., Dethlefsen, M. M., Tøndering, A. S., Lassen, S. B., Meldgaard, J. N., Ringholm, S. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 15, p. 1-15 e13819.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    PGC-1α in exercise and fasting-induced regulation of hepatic UPR in mice

    Kristensen, C. M., Olsen, M. A., Jessen, H., Brandt, N., Meldgaard, J. N. & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 10, p. 1431-1447

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    PGC-1α in aging and lifelong exercise training-mediated regulation of UPR in mouse liver

    Maag Kristensen, C., Brandt, C. T., Jørgensen, Stine Ringholm & Pilegaard, Henriette, Nov 2017, In: Experimental Gerontology. 98, p. 124-133 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    PGC-1α and fasting-induced PDH regulation in mouse skeletal muscle

    Gudiksen, Anders & Pilegaard, Henriette, 10 Apr 2017, In: Physiological Reports. 5, 7, 15 p., e13222.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    PGC-1α and exercise intensity dependent adaptations in mouse skeletal muscle

    Brandt, N., Dethlefsen, M. M., Bangsbo, Jens & Pilegaard, Henriette, 2017, In: P L o S One. 12, 10, 21 p., e0185993.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    PGC-1α Is Required for Exercise- and Exercise Training-Induced UCP1 Up-Regulation in Mouse White Adipose Tissue.

    Jørgensen, Stine Ringholm, Knudsen, Jakob Grunnet, Leick, L., Lundgaard, A., Munk Nielsen, M. & Pilegaard, Henriette, 2013, In: PloS one. 8, 5, p. 1-6 6 p., e64123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    PGC-1{alpha} increases PDH content but does not change acute PDH regulation in mouse skeletal muscle

    Kiilerich, K., Adser, H., Jakobsen, A. H., Pedersen, Per Amstrup, Hardie, D. G., Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2010, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 299, 5, p. R1350-R1359 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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