PGC-1α Is Required for Exercise- and Exercise Training-Induced UCP1 Up-Regulation in Mouse White Adipose Tissue.
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- 331_journal.pone.0064123
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The aim of the present study was to test the hypotheses that 1) a single exercise bout increases UCP1 mRNA in both inguinal (i)WAT and epididymal (e)WAT, 2) UCP1 expression and responsiveness to exercise are different in iWAT and eWAT, 3) PGC-1α determines the basal levels of UCP1 and PRDM16 in WAT and 4) exercise and exercise training regulate UCP1 and PRDM16 expression in WAT in a PGC-1α-dependent manner.
| Original language | English |
|---|---|
| Article number | e64123 |
| Journal | PloS one |
| Volume | 8 |
| Issue number | 5 |
| Pages (from-to) | 1-6 |
| Number of pages | 6 |
| ISSN | 1932-6203 |
| DOIs | |
| Publication status | Published - 2013 |
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