Helle Krogh Johansen

Helle Krogh Johansen

Clinical Professor

Member of:

  • Clinical Microbiology


  1. Published

    Achromobacter spp. genetic adaptation in cystic fibrosis

    Gabrielaite, M., Nielsen, Finn Cilius, Johansen, Helle Krogh & Marvig, R. L., 2021, In: Microbial genomics. 7, 7, 13 p., 000582.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Achromobacter spp. in a Cohort of Non-Selected Pre-and Post-Lung Transplant Recipients

    Crone, C. G., Rezahosseini, O., Schultz, H. H. L., Qvist, T., Johansen, Helle Krogh, Nielsen, Susanne Dam & Perch, Michael, 2022, In: Pathogens. 11, 2, 181.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Pseudomonas aeruginosa Biofilms in the Lungs of Cystic Fibrosis Patients

    Høiby, Niels, Johansen, Helle Krogh, Moser, Claus Ernst, Ciofu, Oana, Jensen, Peter Østrup, Kolpen, Mette, Mandsberg, L., Givskov, Michael, Molin, S. & Bjarnsholt, Thomas, 2011, Biofilm Infections. Springer, p. 167-184 18 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  4. Published

    Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis

    Rossi, E., La Rosa, R., Bartell, J. A., Marvig, R. L., Haagensen, J. A. J., Sommer, L. M., Molin, S. & Johansen, Helle Krogh, 2021, In: Nature Reviews Microbiology. 19, p. 331–342

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    A Dedicated Mycosis Flask Increases the Likelihood of Identifying Candidemia Sepsis

    Ahlström, M. G., Antsupova, V. S., Pedersen, M., Johansen, Helle Krogh, Hansen, D. S. & Knudsen, I. J. D., 2023, In: Journal of Fungi. 9, 4, 15 p., 441.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A cohort study of the Copenhagen CF Centre eradication strategy against Staphylococcus aureus in patients with CF

    Dalbøge, C. S., Pressler, T., Høiby, Niels, Nielsen, Kim G. & Johansen, Helle Krogh, Jan 2013, In: Journal of Cystic Fibrosis. 12, 1, p. 42-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia

    Alanin, M. C., Nielsen, K. G., von Buchwald, Christian, Skov, M., Aanæs, Kasper, Høiby, Niels & Johansen, Helle Krogh, Dec 2015, In: Clinical Microbiology and Infection. 21, 12, p. 1093.e1–1093.e7 7 p., 1093.e.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A new device to prevent contamination of nasal swabs by Staphylococcus aureus in acute rhinosinutitis

    Kirkegaard Kiaer, E., Hakansson, K., Orntoft, S., Bartels, Mette Damkjær, Johansen, Helle Krogh & von Buchwald, Christian, 2020, In: Rhinology Online. 3, p. 39-44

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A novel knee prosthesis model of implant-related osteo- myelitis in rats

    Søe, N. H., Jensen, N. V., Nürnberg, B. M., Jensen, Asger Lundorff, Koch, J., Poulsen, Steen Seier, Pier, G. & Johansen, Helle Krogh, 2012, In: Acta Orthopaedica (Print Edition). 84, 1, p. 92-97 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A prospective survey of Aspergillus spp. in respiratory tract samples: prevalence, clinical impact and antifungal susceptibility

    Mortensen, K. L., Johansen, Helle Krogh, Fuursted, K., Knudsen, J. D., Gahrn-Hansen, B., Jensen, R. H., Howard, S. & Arendrup, M. C., 4 May 2011, In: European Journal of Clinical Microbiology & Infectious Diseases. 30, 11, p. 1355-1363 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A randomized, double-blind, placebo-controlled phase 1 trial of inhaled and intranasal niclosamide: A broad spectrum antiviral candidate for treatment of COVID-19

    Backer, Vibeke, Sjöbring, U., Sonne, J., Weiss, A., Hostrup, Morten, Johansen, Helle Krogh, Becker, V., Sonne, D. P., Balchen, T., Jellingsø, M. & Sommer, M. O. A., 2021, In: The Lancet Regional Health - Europe. 4, 8 p., 100084.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A retrospective review of Achromobacter species and antibiotic treatments in patients with primary ciliary dyskinesia

    Holgersen, M. G., Marthin, J. K., Johansen, Helle Krogh & Nielsen, Kim G., 2021, In: Chronic Respiratory Disease. 18

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Activation of the immune defence in blood and lung after ginseng treatment in a rat model with chronic Pseudomonas aeruginosa pneumonia

    Song, Z. J., Wu, H., Kharazmi, A., Faber, V., Moser, C., Johansen, Helle Krogh & Høiby, Niels, 1999, In: Netherlands Journal of Medicine. 54, p. 70-70

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Active and Passive Immunization Against Staphylococcus aureus Periprosthetic Osteomyelitis in Rats

    Søe, Niels Henrik, Jensen, N. V., Jensen, Asger Lundorff, Koch, J., Poulsen, Steen Seier, Pier, G. B. & Johansen, Helle Krogh, 2017, In: In Vivo. 31, 1, p. 45-50 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Active immunization against Staphylococcus aureus (oca+) periprosthetic osteomyelitis in rats

    Koch, J., Johansen, Helle Krogh, Vedel-Jensen, N., Jensen, A., poulsen, S. & Søe, H., 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  16. Published

    Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

    Folkesson, A., Jelsbak, L., Yang, L., Johansen, Helle Krogh, Ciofu, Oana, Høiby, Niels & Molin, S., Dec 2012, In: Nature Reviews. Microbiology. 10, 12, p. 841-851 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis Patients

    La Rosa, R., Johansen, Helle Krogh & Molin, S., 2019, In: Metabolites. 9, 10, 15 p., 234.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Adaptive Evolution of Pseudomonas aeruginosa in Human Airways Shows Phenotypic Convergence Despite Diverse Patterns of Genomic Changes

    Espaillat, A., Colque, C. A., Rago, D., La Rosa, R., Molin, S. & Johansen, Helle Krogh, 2024, In: MOLECULAR BIOLOGY AND EVOLUTION . 41, 2, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Adaptive interactions of achromobacter spp. With pseudomonas aeruginosa in cystic fibrosis chronic lung co-infection

    Sandri, A., Haagensen, J. A. J., Veschetti, L., Johansen, Helle Krogh, Molin, S., Malerba, G., Signoretto, C., Boaretti, M. & Lleo, M. M., 2021, In: Pathogens. 10, 8, 12 p., 978.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Amphotericin B lipid soluble formulations versus amphotericin B in cancer patients with neutropenia

    Johansen, Helle Krogh & Gøtzsche, P. C., 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-30 30 p., CD000969.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Amphotericin B lipid soluble formulations vs amphotericin B in cancer patients with neutropenia (Cochrane Review)

    Johansen, Helle Krogh & Gøtzsche, P. C., 2002, The Cochrane Library, Issue 2. Oxford: Update Software (updated), p. -

    Research output: Chapter in Book/Report/Conference proceedingReport chapterResearch

  22. Published

    Amphotericin B versus fluconazole for controlling fungal infections in neutropenic cancer patients

    Johansen, Helle Krogh & Gøtzsche, P. C., 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-38 38 p., CD000239.

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Antibiofilm Properties of Acetic Acid

    Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Antibiotic resistance in Pseudomonas aeruginosa and adaptation to complex dynamic environments

    Sommer, L. M., Johansen, Helle Krogh & Molin, S., 2020, In: Microbial Genomics. 6, 5, p. 1-6 6 p., 000370.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    Antibody response to Pseudomonas aeruginosa in cystic fibrosis patients: a marker of therapeutic success? - A 30-year cohort study of survival in Danish CF patients after onset of chronic P. aeruginosa lung infection

    Johansen, Helle Krogh, Nørregaard, L., Gøtzsche, P. C., Pressler, T., Koch, C. & Høiby, Niels, 2004, In: Pediatric Pulmonology. 37, 5, p. 427-432

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Antifungal prophylactic or empiric therapy vs. placebo or no treatment in cancer patients with neutropenia

    Gøtzsche, P. C. & Johansen, Helle Krogh, 1997, Infectious Diseases Module of the Cochrane Database of Systematic Reviews. Oxford: The Cochrane Collaboration, Issue 2

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  27. Published

    Antimicrobial resistance of Pseudomonas aeruginosa in a cystic fibrosis population after introduction of a novel cephalosporin/β-lactamase inhibitor combination

    Katzenstein, T. L., Faurholt-Jepsen, D., Qvist, T., Jensen, Peter Østrup, Pressler, T., Johansen, Helle Krogh & Kolpen, Mette, 2023, In: APMIS. 131, 8, p. 419-425

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Aspergillus species and other molds in respiratory samples from patients with cystic fibrosis: a laboratory-based study with focus on Aspergillus fumigatus azole resistance

    Mortensen, K. L., Jensen, R. H., Johansen, Helle Krogh, Skov, M., Pressler, T., Howard, S. J., Leatherbarrow, H., Mellado, E. & Arendrup, M. C., 1 Jun 2011, In: Journal of Clinical Microbiology. 49, 6, p. 2243-51 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Autoantibodies to pancreatic hsp60 precede the development of glucose intolerance in patients with cystic fibrosis

    Jensen, P., Johansen, Helle Krogh, Carmi, P., Høiby, Niels & Cohen, I. R., 2001, In: J. Autoimmunity. 17, p. 165-172

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P-aeruginosa lung infection in Cftr(-/-) mice

    Hoffmann, N., Lee, B., Hentzer, M., Rasmussen, T. B., Song, Z. J., Johansen, Helle Krogh, Givskov, M. C. & Høiby, Niels, 2007, In: Antimicrobial Agents and Chemotherapy. 51, 10, p. 3677-3687 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Azole-Resistant Aspergillus fumigatus Among Danish Cystic Fibrosis Patients: Increasing Prevalence and Dominance of TR34/L98H

    Risum, M., Hare, R. K., Gertsen, J. B., Kristensen, L., Johansen, Helle Krogh, Helweg-Larsen, J., Abou-Chakra, N., Pressler, T., Skov, M., Jensen-Fangel, S. & Arendrup, Maiken Cavling, 2020, In: Frontiers in Microbiology. 11, 10 p., 1850.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Bacterial evolution in PCD and CF patients follows the same mutational steps

    Sommer, L. M., Alanin, M. C., Marvig, R. L., Nielsen, Kim G., Høiby, Niels, von Buchwald, Christian, Molin, S. & Johansen, Helle Krogh, 2016, In: Scientific Reports. 6, 8 p., 28732.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Bacterial persisters in long-term infection: Emergence and fitness in a complex host environment

    Bartell, J. A., Cameron, D. R., Mojsoska, B., Haagensen, J. A. J., Pressler, T., Sommer, L. M., Lewis, K., Molin, S. & Johansen, Helle Krogh, 2020, In: PLOS Pathogens. 16, 12 December, e1009112.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Bacterial re-colonization occurs early after lung transplantation in cystic fibrosis patients

    Holm, A. E., Schultz, H. H. L., Johansen, Helle Krogh, Pressler, T., Lund, T. K., Iversen, M. & Perch, Michael, 2021, In: Journal of Clinical Medicine. 10, 6, 11 p., 1275.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Begrænsninger i publikationsrettighederne i industriinitierede kliniske forsøg: sekundærpublikation

    Gotzsche, P. C., Hrobjartsson, A., Johansen, Helle Krogh, Haahr, M. T., Altman, D. G. & Chan, A. W., 2006, In: Ugeskrift for læger. 168, 25, p. 2467-2469 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Biofilm ved kronisk rhinosinuitis og cystisk fibrose

    Fisker, J., Buchwald, C. V. & Johansen, Helle Krogh, 7 Feb 2011, In: Ugeskrift for Laeger. 173, 6, p. 417-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

    Burmølle, Mette, Thomsen, T. R., Fazli, M., Dige, I., Christensen, L., Homøe, Preben, Tvede, M., Nyvad, B., Tolker-Nielsen, Tim, Givskov, Michael, Moser, Claus Ernst, Kirketerp-Møller, K., Johansen, Helle Krogh, Høiby, Niels, Jensen, Peter Østrup, Sørensen, Søren Johannes & Bjarnsholt, Thomas, 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 324-336 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    CT of the paranasal sinuses is not a valid indicator for sinus surgery in CF patients

    Rasmussen, J., Aanæs, Kasper, Norling, R., Nielsen, K. G., Johansen, Helle Krogh & von Buchwald, C., 2012, In: Journal of Cystic Fibrosis. 11, 2, p. 93-99

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study

    Alanin, M. C., Pressler, T., Aanæs, Kasper, Ekstrøm, Claus Thorn, Skov, M., Johansen, Helle Krogh, Nielsen, Kim G., von Buchwald, Christian & Høiby, Niels, 2018, In: Health Services Research. 1, 8, 5 p., e52.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Cellular responses of A549 alveolar epithelial cells to serially collected Pseudomonas aeruginosa from cystic fibrosis patients at different stages of pulmonary infection

    Hawdon, N. A., Aval, P. S., Barnes, R. J., Gravelle, S. K., Rosengren, J., Khan, S., Ciofu, Oana, Johansen, Helle Krogh, Høiby, Niels & Ulanova, M., 1 Jul 2010, In: FEMS Immunology and Medical Microbiology. 59, 2, p. 207-20 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Chronic Pseudomonas aeruginosa lung infection in normal and athymic rats

    Johansen, Helle Krogh, Espersen, F., Pedersen, S. S., Hougen, H. P., Rygaard, J. & Høiby, Niels, 1993, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 101, 3, p. 207-225 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Chronic Pseudomonas aeruginosa lung infection is more severe in Th2 responding BALB/c mice compared to Th1 responding C3H/HeN mice

    Moser, Claus Ernst, Johansen, Helle Krogh, Song, Z., Hougen, H. P., Rygaard, J. & Høiby, Niels, 1997, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 105, 11, p. 838-42 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Chronic infection with Stenotrophomonas maltophilia in patients with cystic fibrosis at the Copenhagen CF centre

    Dalbøge, C. S., Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 17 Jun 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  44. Published

    Chronic pulmonary infection with Stenotrophomonas maltophilia and lung function in patients with cystic fibrosis

    Dalbøge, C. S., Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 1 Sep 2011, In: Journal of Cystic Fibrosis. 10, 5, p. 318-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Clinical care of children with primary ciliary dyskinesia

    Lucas, J. S., Alanin, M. C., Collins, S., Harris, A., Johansen, Helle Krogh, Nielsen, Kim G., Papon, J. F., Robinson, P. & Walker, W. T., 2017, In: Expert Review of Respiratory Medicine. 11, 10, p. 779-790 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  46. Published

    Clinical effects of sinus surgery and adjuvant therapy in cystic fibrosis patients - can chronic lung infections be postponed?

    Aanæs, Kasper, Johansen, Helle Krogh, Skov, M., Buchvald, F. F., Hjuler, Thomas, Pressler, T., Høiby, Niels, Nielsen, Kim G. & von Buchwald, Christian, 2013, In: Rhinology. 51, 3, p. 222-230 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Co-delivery of ciprofloxacin and colistin using microcontainers for bacterial biofilm treatment

    Birk, S. E., Mazzoni, C., Mobasharah Javed, M., Borre Hansen, M., Johansen, Helle Krogh, Anders Juul Haagensen, J., Molin, S., Hagner Nielsen, L. & Boisen, A., 2021, In: International Journal of Pharmaceutics. 599, 120420.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Colonisation and infection of the paranasal sinuses in cystic fibrosis patients is accompanied by a reduced PMN response

    Johansen, Helle Krogh, Aanæs, Kasper, Pressler, T., Nielsen, Kim G., Fisker, J., Skov, M., Høiby, Niels & von Buchwald, Christian, Dec 2012, In: Journal of Cystic Fibrosis. 11, 6, p. 525-531 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Comparing whole-genome sequencing with sanger sequencing for spa typing of methicillin-resistant staphylococcus aureus

    Bartels, Mette Damkjær, Petersen, A., Worning, P., Nielsen, J. B., Larner-Svensson, H., Johansen, Helle Krogh, Andersen, Leif Percival, Jarløv, J. O., Boye, K., Larsen, A. R. & Westh, Henrik T., 1 Dec 2014, In: Journal of clinical microbiology. 52, 12, p. 4305-4308 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Compensatory evolution of Pseudomonas aeruginosa’s slow growth phenotype suggests mechanisms of adaptation in cystic fibrosis

    La Rosa, R., Rossi, E., Feist, A. M., Johansen, Helle Krogh & Molin, S., 2021, In: Nature Communications. 12, 1, 3186.

    Research output: Contribution to journalJournal articleResearchpeer-review

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