Gitta Wörtwein

Gitta Wörtwein

Associate Professor

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    ORCID: 0000-0001-6981-7885

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    1. Published

      Enhanced self-administration of alcohol in muscarinic acetylcholine M4 receptor knockout mice

      de la Cour, C., Sørensen, G., Wörtwein, Gitta, Weikop, Pia, Nielsen, D. D., Fink-Jensen, Anders & Molander, A., 5 Jan 2015, In: European Journal of Pharmacology. 746, p. 1-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Retention and relearning of spatial delayed alternation in rats after combined or sequential lesions of the prefrontal and parietal cortex

      Wörtwein, Gitta, Mogensen, J. & Divac, I., 1993, In: Acta Neurobiologiae Experimentalis. 53, p. 357-366

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Place learning by fimbria-fornix transected rats in a modified water maze

      Wörtwein, Gitta, Særup, L. H., Charlottenfeld-Starpov, D. & Mogensen, J., 1995, In: International Journal of Neuroscience. 82, p. 71-81

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Mekanismer ved funktionel restitution efter hjerneskader

      Wörtwein, Gitta, 2009, Klinisk neuropsykologi. Gade, A., Gerlach, C., Starrfelt, R. & Møller Pedersen, P. (eds.). København: Frydenlund Academic, p. 480-488

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

    5. Published

      Responses of young and aged rat CNS to partial cholinergic immunolesions and NGF treatment

      Wörtwein, Gitta, Yu, J., Toliver-Kinsky, T. & Perez-Polo, J., 1998, In: Journal of Neuroscience Research. Vol. 52, p. 322-333

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Retention and relearning of spatial delayed alternation in rats after ablation of the prefrontal or total non-prefrontal isocortex

      Wörtwein, Gitta, Mogensen, J. & Divac, I., 1994, In: Behavioural Brain Research. 63, p. 127-131

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Cortical area in the rat that mediates visual pattern discrimination

      Wörtwein, Gitta, Mogensen, J., Williams, G., Carlos, J. H. & Divac, I., 1994, In: Acta Neurobiologiae Experimentalis. 54, p. 365-376

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Model for aging inthe basal forebrain cholinergic system

      Wörtwein, Gitta, Gu, Z., Yu, J. & Perez-Polo, J. R., 2000, In: Antioxidants & Redox Signaling. 2,3, p. 437-447

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Effects of maternal separation on neuropetide Y and calcitonin gene-related peptide in "depressed" Flinders Sensitive Line rats: A study of gene-environment interactions

      Wörtwein, Gitta, Husum, H., Andersson, W., Bolwig, T. G. & Mathe, A. A., 2006, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 30, 4, p. 684-693 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Reduced cocaine self-administration in muscarinic M5 acetylcholine receptor-deficient mice

      Thomsen, M. M., Woldbye, David Paul Drucker, Wörtwein, Gitta, Fink-Jensen, A., Wess, J. & Caine, S. B., 2005, In: Journal of Neuroscience. Vol. 25, p. 8141-49

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Involvement of Y5 receptors in neuropeptide Y agonist-induced analgesic-like effect in the rat hot plate test

      Thomsen, M., Wörtwein, Gitta, Olesen, M. V., Begtrup, M., Havez, S., Bolwig, T. G. & Woldbye, David Paul Drucker, 2007, In: Brain Research. 1155, p. 49-55

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Effects of acute and chronic aripiprazole treatment on choice between cocaine self-administration and food under a concurrent schedule of reinforcement in rats

      Thomsen, M., Fink-Jensen, Anders, Woldbye, David Paul Drucker, Wörtwein, Gitta, Sager, T., Holm, R., Pepe, L. & Barak Caine, S., 2008, In: Psychopharmacology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Differential roles for neuropeptide Y Y1 and Y5 receptors in anxiety and sedation

      Sørensen, G., Lindberg, C., Wörtwein, Gitta, Bolwig, T. G., Woldbye, David Paul Drucker & Sørensen, G., 1 Sep 2004, In: Journal of Neuroscience Research. 77, 5, p. 723-9 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Aripiprazole blocks acute self-administration of cocaine and is not self-administered in mice

      Sørensen, G., Sager, T. N., Petersen, Jørgen Holm, Brennum, L. T., Thøgersen, P., Hee Bengtsen, C., Thomsen, M., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, 2008, In: Psychopharmacology. 199, 1, p. 37-46 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Neuropeptide Y infusion into the shell region of the rat nucleus accumbens increases extracellular levels of dopamine

      Sørensen, G., Wegener, G., Hasselstrøm, J., Hansen, T. V. O., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, 2009, In: NeuroReport. 20, 11, p. 1023-6 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Neuropeptide Y Y5 receptor antagonism causes faster extinction and attenuates reinstatement in cocaine-induced place preference

      Sørensen, G., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, Apr 2013, In: Pharmacology, Biochemistry and Behavior. 105, p. 151-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Addiction-Related Effects of DOV 216,303 and Cocaine: A Comparative Study in the Mouse

      Sørensen, G., Husum, H., Brennum, L. T., Bundgaard, C., Montezinho, L. C. P., Mørk, A., Wörtwein, Gitta & Woldbye, David Paul Drucker, Jun 2014, In: Basic & Clinical Pharmacology & Toxicology. 114, 6, p. 451-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation

      Sørensen, G., Rickhag, Karl Mattias, Leo, D., Lycas, M. D., Ridderstrøm, P. H., Weikop, P., Lilja, J. H., Rifes, P., Herborg, Freja, Woldbye, David Paul Drucker, Wörtwein, Gitta, Gainetdinov, R. R., Fink-Jensen, Anders & Gether, Ulrik, 2021, In: Journal of Biological Chemistry. 297, 6, 101361.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Neuropeptide Y Y5 receptor antagonism attenuates cocaine-induced effects in mice.

      Sørensen, G., Jensen, M., Weikop, Pia, Nielsen, D. D., Christiansen, S. H. O., Loland, Claus Juul, Bengtsen, C. H., Petersen, Jørgen Holm, Fink-Jensen, Anders, Wörtwein, Gitta & Woldbye, David Paul Drucker, Feb 2012, In: Psychopharmacology. 222, p. 565-577 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      The glucagon-like peptide 1 (GLP-1) receptor agonist exendin-4 reduces cocaine self-administration in mice

      Sorensen, G., Reddy, I. A., Weikop, Pia, Graham, D. L., Stanwood, G. D., Wörtwein, Gitta, Galli, A. & Fink-Jensen, Anders, 1 Oct 2015, In: Physiology & Behavior. 149, p. 262-268 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Increased cocaine self-administration in M4 muscarinic acetylcholine receptor knockout mice.

      Schmidt, L. S., Thomsen, M., Weikop, Pia, Nielsen, D. D., Wess, J., Woldbye, David Paul Drucker, Wörtwein, Gitta & Fink-Jensen, Anders, 2011, In: Psychopharmacology. 216, 3, p. 367-378 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Increased amphetamine-induced locomotor activity, sensitization, and accumbal dopamine release in M5 muscarinic receptor knockout mice

      Schmidt, L. S., Miller, A. D., Lester, D. B., Bay-Richter, C., Schülein, C., Frikke-Schmidt, H., Wess, J., Blaha, C. D., Woldbye, David Paul Drucker, Fink-Jensen, Anders & Wörtwein, Gitta, 2010, In: Psychopharmacology. 207, 4, p. 547-58 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      The effect of subchronic fluoxetine treatment on learning and memory in adolescent rats

      Sass, A. & Wörtwein, Gitta, 2012, In: Behavioural Brain Research. 228, 1, p. 169-75 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Subjective perception of cocaine reward in mice assessed by a single exposure place preference (sePP) paradigm

      Runegaard, A. H., Jensen, Kathrine Louise, Dencker, D., Wörtwein, Gitta & Gether, Ulrik, 2017, In: Journal of Neuroscience Methods. 289, p. 85-92 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      G protein-coupled receptor signaling in VTA dopaminergic neurons bidirectionally regulates the acute locomotor response to amphetamine but does not affect behavioral sensitization

      Runegaard, A. H., Dencker, D., Wörtwein, Gitta & Gether, Ulrik, 2019, In: Neuropharmacology. 161, 107663.

      Research output: Contribution to journal › Review › Research › peer-review

    26. Published

      Initial rewarding effects of cocaine and amphetamine assessed in a day using the single-exposure place preference protocol

      Runegaard, A. H., Jensen, Kathrine Louise, Wörtwein, Gitta & Gether, Ulrik, 2019, In: European Journal of Neuroscience. 50, 3, p. 2156-2163 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons

      Runegaard, A. H., Sørensen, Andreas Toft, Fitzpatrick, C. M., Jørgensen, Søren Heide, Petersen, A. V., Hansen, Nikolaj Winther, Weikop, Pia, Andreasen T., Jesper, Mikkelsen, Jens D., Perrier, Jean-Francois Marie, Woldbye, David Paul Drucker, Rickhag, Karl Mattias, Wörtwein, Gitta & Gether, Ulrik, 2018, In: eNeuro. 5, 3, 26 p., e0345.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Cholinergic control of nerve growth factor in adult rats: evidence from cortical cholinergic deafferentation and chronic drug treatment

      Rossner, S., Wörtwein, Gitta, Gu, Z., Yu, J., Schliebs, R., Bigl, V. & Perez-Polo, J., 1998, In: Journal of Neurochemistry. Vol. 69, p. 947-953

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Membrane permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.

      Rickhag, Karl Mattias, Owens, W., Winkler, M., Strandfelt, K. N., Rathje, Mette, Sørensen, G., Andresen, B., Madsen, Kenneth Lindegaard, Nygaard Jørgensen, T., Wörtwein, Gitta, Woldbye, David Paul Drucker, Sitte, H. H., Daws, L. C. & Gether, Ulrik, 2013, In: Journal of Biological Chemistry. 288, p. 27534-44 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter

      Rickhag, Karl Mattias, Herborg, Freja, Sørensen, G., Strandfelt, K. N., Andresen, B., Gotfryd, K., Madsen, Kenneth Lindegaard, Vestergaard-Klewe, I., Ammendrup-Johnsen, I., Eriksen, J., Newman, A. H., Füchtbauer, E., Gomeza, J., Woldbye, David Paul Drucker, Wörtwein, Gitta & Gether, Ulrik, 2013, In: Nature Communications. 4, p. 1-13 13 p., 1580.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Glucagon-like peptide 1 receptor activation regulates cocaine actions and dopamine homeostasis in the lateral septum by decreasing arachidonic acid levels

      Reddy, I. A., Pino, J. A., Weikop, Pia, Osses, N., Sørensen, G., Bering, T., Valle, C., Bluett, R. J., Erreger, K., Wörtwein, Gitta, Reyes, J. G., Graham, D., Stanwood, G. D., Hackett, T. A., Patel, S., Fink-Jensen, Anders, Torres, G. E. & Galli, A., 2016, In: Translational Psychiatry. 6, 11 p., e809.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      5-HT2A Receptor Binding in the Frontal Cortex of Parkinson's Disease Patients and Alpha-Synuclein Overexpressing Mice: A Postmortem Study

      Rasmussen, N. B., Olesen, M. V., Brudek, T., Plenge, P., Klein, A. B., Westin, J. E., Fog, K., Wörtwein, Gitta & Aznar, S., 2016, In: Parkinson’s Disease. 2016, 8 p., 3682936.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Characterization of epibatidine binding to medial habenula: potential role in analgesia

      Plenge, P. K., Mellerup, Erling Thyge & Wörtwein, Gitta, 2002, In: Journal of Pharmacology and Experimental Therapeutics. vol. 302, p. 759-65

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Nortriptyline mediates behavioral effects without affecting hippocampal cytogenesis in a genetic rat depression model

      Petersén, A., Wörtwein, Gitta, Gruber, S. H. M., El-Khoury, A. & Mathé, A. A., 2009, In: Neuroscience Letters. 451, 2, p. 148-51 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Escitalopram reduces increased hippocampal cytogenesis in a genetic rat depression model

      Petersén, A., Wörtwein, Gitta, Gruber, S. H. M. & Mathé, A. A., 2008, In: Neuroscience Letters. 436, 3, p. 305-8 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Electroconvulsive stimulation results in long-term survival of newly generated hippocampal neurons in rats

      Olesen, M. V., Wörtwein, Gitta, Folke, J. & Pakkenberg, B., Jan 2017, In: Hippocampus. 27, 1, p. 52-60 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Electroconvulsive Stimulation, but not Chronic Restraint Stress, Causes Structural Alterations in Adult Rat Hippocampus: A Stereological Study

      Olesen, M. V., Wörtwein, Gitta & Pakkenberg, B., Jan 2015, In: Hippocampus. 25, 1, p. 72-80 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine

      Nielsen, D. D., Weikop, Pia, Sørensen, G., Woldbye, David Paul Drucker, Wörtwein, Gitta, Wess, J. & Fink-Jensen, Anders, 2012, In: Psychopharmacology. 224, 2, p. 277-87 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Inactivation of the cholinergic M4 receptor results in a disinhibited endophenotype predicting alcohol use

      Molander, A., Thorbek, D. D., Lysne, C., Weikop, Pia, Fink-Jensen, Anders & Wörtwein, Gitta, 2022, In: Behavioural Brain Research. 430, 10 p., 113921.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Associative an nonassociative learning after chronic imipramine in rats

      Mogensen, J., Svendsen, G., Tølbøll Lauritsen, K., Ermens, P., Hasman, A., Elvertorp, S., Plenge, P. K., Mellerup, Erling Thyge & Wörtwein, Gitta, 2003, In: Pharmacology, Biochemistry and Behavior. Vol. 76, p. 197-212

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Dyremodeller i neuropsykiatrisk forskning

      Mogensen, J. & Wörtwein, Gitta, 1999, Neuropsykiatriske Aspekter. Danmark, p. 116-123

      Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research

    42. Published

      Functional and neurochemical profile of place learning after L-nitro-arginine in the rat

      Mogensen, J., Wörtwein, Gitta, Hasman, A., Nielsen, P. & Wang, Q., 1995, In: Neurobiology of Learning and Memory. 63, p. 54-65

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Place learning during inhibition of nitric oxide synthase in the rat

      Mogensen, J., Hasman, A. & Wörtwein, Gitta, 1995, In: Homeostasis. 36, p. 12-18

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      L-Nitroarginine reduces hippocampal mediation of place learning in the rat

      Mogensen, J., Wörtwein, Gitta, Gustafson, B. & Ermens, P., 1995, In: Neurobiology of Learning and Memory. 64, p. 17-24

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Analysis of response patterns during prefrontally ablated rats acquisition of an egocentric spatial task in an 8-arm radialmaze

      Mogensen, J., Montero, A. & Wörtwein, Gitta, 2003, In: Homeostasis. Vol. 42, no.1-2, p. 52-59

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Egocentric spatial orientation in a water maze by rats subjected to transection of the fimbria-fornix and/or ablation of the prefrontal cortex

      Mogensen, J., Moustgaard, A., Khan, U., Wörtwein, Gitta & Sandager Nielsen, K., 2005, In: Brain Research Bulletin. 65, 1, p. 41-58

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Place learning and object recognition by rats subjected to transection of the fimbria-fornix and/or ablation of the prefrontal cortex

      Mogensen, J., Lauritsen, K. T., Elvertorp, S., Hasman, A., Moustgaard, A. & Wörtwein, Gitta, 2004, In: Brain Research Bulletin. Vol. 63, no. 3, p. 217-36

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Place learning in scolopamine-treated rats: the role of distal cues and catecholaminergic mediation

      Mogensen, J., Christensen, L. H., Johansson, A., Wörtwein, Gitta, Bang, L. E. & Holm, S., 2002, In: Neurobiology of Learning and Memory. 78(1), p. 139-66

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Proinflammatory biomarkers are associated with prediabetes in patients with schizophrenia

      Mller, M., Fredholm, S., Jensen, M. E., Wörtwein, Gitta, Larsen, J. R., Vilsbøll, Tina, Ødum, Niels & Fink-Jensen, Anders, 2022, In: CNS Spectrums. 27, 3, 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Increased numbers of orexin/hypocretin neurons in a genetic rat depression model

      Mikrouli, E., Wörtwein, Gitta, Soylu, R., Mathé, A. A. & Petersén, Å., 2011, In: Neuropeptides (Sheffield). 45, 6, p. 401-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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