Flemming Pociot

Flemming Pociot

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


  1. Published

    25-Hydroxyvitamin D and Peripheral Immune Mediators: Results from Two Nationwide Danish Pediatric Cohorts

    Thorsen, S., Pipper, C., Skogstrand, K., Pociot, Flemming & Svensson, Jannet, Apr 2017, In: Nutrients. 9, 4, 10 p., 365.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    25-hydroxyvitamin D, autoantigenic and total antibody concentrations: Results from a Danish case-control study of newly diagnosed patients with childhood type 1 diabetes and their healthy siblings

    Thorsen, S. U., Pipper, C. B., Johannesen, Jesper, Mortensen, H. B., Pociot, Flemming & Svensson, Jannet, 2018, In: Scandinavian Journal of Immunology. 87, 1, p. 46-53 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Skap2, a candidate gene for type 1 diabetes, regulates b-cell apoptosis and glycemic control in newly diagnosed patients

    Fløyel, T., Meyerovich, K., Prause, Michala Cecilie Burstein, Kaur, S., Frørup, C., Mortensen, H. B., Nielsen, L. B., Pociot, Flemming, Cardozo, A. K. & Størling, Joachim, 2021, In: Diabetes. 70, 2, p. 464-476 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells

    Marroqui, L., Dos Santos, R. S., Fløyel, T., Grieco, F. A., Santin, I., Op de Beeck, A., Marselli, L., Marchetti, P., Pociot, Flemming & Eizirik, D. L., Nov 2015, In: Diabetes. 64, 11, p. 3808-17 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A Dual Systems Genetics Approach Identifies Common Genes, Networks, and Pathways for Type 1 and 2 Diabetes in Human Islets

    Kaur, S., Mirza, A. H., Overgaard, A. J., Pociot, Flemming & Størling, Joachim, 2021, In: Frontiers in Genetics. 12, 630109.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A Gluten-Free Diet during Pregnancy and Early Life Increases Short Chain Fatty Acid-Producing Bacteria and Regulatory T Cells in Prediabetic NOD Mice

    Johansen, Valdemar Brimnes Ingemann, Færø, D., Buschard, K., Kristiansen, Karsten, Pociot, Flemming, Kiilerich, P., Josefsen, K., Haupt-jorgensen, M. & Antvorskov, J. C., 2023, In: Cells. 12, 12, 15 p., 1567.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells

    Vestergaard, A. L., Blankestijn, M., Stahl, J. L., Pallesen, E. M. H., Bang-Berthelsen, C. H., Pociot, Flemming, Novotny, G. W., Lundh, M. & Mandrup-Poulsen, Thomas, 2016, In: International Journal of Molecular Sciences (Online). 17, 6, 8 p., 896.

    Research output: Contribution to journalComment/debateResearchpeer-review

  8. Published

    A human phenome-interactome network of protein complexes implicated in genetic disorders

    Lage, K., Karlberg, E. O., Størling, Z. M., Olason, P. I., Pedersen, A. G., Rigina, O., Hinsby, A. M., Tümer, Asuman Zeynep, Pociot, Flemming, Tommerup, Niels, Moreau, Y. & Brunak, S., 2007, In: Nature Biotechnology. 25, 3, p. 309-16 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3

    Concannon, P., Onengut-Gumuscu, S., Todd, J. A., Smyth, D. J., Pociot, Flemming, Bergholdt, R., Akolkar, B., Erlich, H. A., Hilner, J. E., Julier, C., Morahan, G., Nerup, J., Nierras, C. R., Chen, W. M. & Rich, S. S., 2008, In: Diabetes. 57, 10, p. 2858-2861 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A non-synonymous variant in SLC30A8 is not associated with type 1 diabetes in the Danish population

    Brorsson, C., Bergholdt, R., Sjogren, M., Eising, S., Sorensen, K. M., Hougaard, D. M., Orho-Melander, M., Groop, L. & Pociot, Flemming, 2008, In: Molecular Genetics and Metabolism. 94, 3, p. 386-388 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A possible association between a dysfunctional skin barrier (filaggrin null-mutation status) and diabetes: a cross-sectional study

    Thyssen, Jacob Pontoppidan, Linneberg, Allan René, Carlsen, B. C., Johansen, Jeanne Duus, Engkilde, K., Hansen, Torben, Pociot, Flemming, Pedersen, Oluf Borbye, Meldgaard, M., Szecsi, P. B., Stender, Steen & Menné, T., 1 Jan 2011, In: BMJ Open. 1, 1, p. e000062 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes

    Fukaya, M., Brorsson, C. A., Meyerovich, K., Catrysse, L., Delaroche, D., Vanzela, E. C., Ortis, F., Beyaert, R., Nielsen, L. B., Andersen, M. L. M., Mortensen, H. B., Pociot, Flemming, van Loo, G., Størling, J. & Cardozo, A. K., Jan 2016, In: Molecular endocrinology (Baltimore, Md.). 30, 1, p. 48-61 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Abnormal islet sphingolipid metabolism in type 1 diabetes

    Holm, L. J., Krogvold, L., Hasselby, Jane Preuss, Kaur, S., Claessens, L. A., Russell, M. A., Mathews, C. E., Hanssen, K. F., Morgan, N. G., Koeleman, B. P. C., Roep, B. O., Gerling, I. C., Pociot, Flemming, Dahl-Jørgensen, K. & Buschard, K., 2018, In: Diabetologia. 61, 7, p. 1650-1661 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Alu Elements as Novel Regulators of Gene Expression in Type 1 Diabetes Susceptibility Genes?

    Kaur, S. & Pociot, Flemming, 2015, In: Genes. 6, 3, p. 577-91 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Anti-diabetic potential of Urtica Dioica: current knowledge and future direction

    Chehri, A., Yarani, R., Yousefi, Z., Novin Bahador, T., Shakouri, S. K., Ostadrahimi, A., Mobasseri, M., Pociot, Flemming & Araj-Khodaei, M., 2022, In: Journal of Diabetes and Metabolic Disorders. 21, 1, p. 931-940 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Anti-diabetic potential of plant alkaloids: Revisiting current findings and future perspectives

    Rasouli, H., Yarani, R., Pociot, Flemming & Popović-Djordjević, J., May 2020, In: Pharmacological Research. 155, 15 p., 104723.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Assisting the implementation of screening for type 1 diabetes by using artificial intelligence on publicly available data

    Teixeira, P. F., Battelino, T., Carlsson, A., Gudbjörnsdottir, S., Hannelius, U., von Herrath, M., Knip, M., Korsgren, O., Elding Larsson, H., Lindqvist, A., Ludvigsson, J., Lundgren, M., Nowak, C., Pettersson, P., Pociot, Flemming, Sundberg, F., Åkesson, K., Lernmark, Å. & Forsander, G., 2024, In: Diabetologia. 67, 6, p. 985-994

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Association between Neonatal Whole Blood Iron Content and Cytokines, Adipokines, and Other Immune Response Proteins

    Thorsen, S. U., Pipper, C. B., Ellervik, Christina, Pociot, Flemming, Kyvsgaard, J. N. & Svensson, Jannet, 2019, In: Nutrients. 11, 3, 12 p., 543.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Association of a functional 17beta-estradiol sensitive IL6-174G/C promoter polymorphism with early-onset type 1 diabetes in females

    Kristiansen, O. P., Nolsøe, R. L., Larsen, L., Gjesing, A. M. P., Johannesen, J., Larsen, Z. M. E., Lykkesfeldt, A. E., Karlsen, A. E., Pociot, Flemming, Mandrup-Poulsen, Thomas & DIEGG, D., 15 May 2003, In: Human Molecular Genetics. 12, 10, p. 1101-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Bone Mineral Density Is Increased in 276 Danish Children and Adolescents with Type-1-Diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Olsen, B. S., Pociot, Flemming & Johannesen, Jesper, 2018, ESPE Abstracts. Bioscientifica, Vol. 89. p. 113 (Hormone Research in Paediatrics).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  21. Published

    Bone turnover markers during the remission phase in children and adolescents with type 1 diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Jensen, Andreas Kryger, Jørgensen, Niklas Rye, Olsen, B. S., Svensson, Jannet, Pociot, Flemming & Johannesen, Jesper, 2020, In: Pediatric Diabetes. 21, 2, p. 366-376 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Bone turnover markers in children and adolescents with type 1 diabetes

    Madsen, J. O. B., Jørgensen, N. R., Pociot, Flemming & Johannesen, Jesper, 2019, In: Pediatric Diabetes. 20, 5, p. 510-522

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Breast Milk-Derived Extracellular Vesicles Enriched in Exosomes From Mothers With Type 1 Diabetes Contain Aberrant Levels of microRNAs

    Mirza, A. H., Kaur, S., Nielsen, L. B., Størling, J., Yarani, R., Roursgaard, Martin, Mathiesen, Elisabeth, Damm, Peter, Svare, J., Mortensen, H. B. & Pociot, Flemming, 2019, In: Frontiers in Immunology. 10, p. 2543

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients

    Fløyel, T., Brorsson, C., Nielsen, L. B., Miani, M., Bang-Berthelsen, C. H., Friedrichsen, M., Overgaard, A. J., Berchtold, L. A., Wiberg, A., Poulsen, P., Hansen, L., Rosinger, S., Boehm, B. O., Ram, R., Nguyen, Q., Mehta, M., Morahan, G., Concannon, P., Bergholdt, R., Nielsen, J. H. & 7 others, Reinheckel, T., von Herrath, M., Vaag, Allan, Eizirik, D. L., Mortensen, H. B., Størling, J. & Pociot, Flemming, 15 Jul 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 28, p. 10305-10310 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Capturing residual beta cell function in type 1 diabetes

    Pociot, Flemming, 2019, In: Diabetologia. 62, 1, p. 28-32 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Cathepsin c regulates cytokine-induced apoptosis in β-cell model systems

    Fløyel, T., Frørup, C., Størling, Joachim & Pociot, Flemming, 2021, In: Genes. 12, 11, 1694.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Cell Type-Selective Expression of Circular RNAs in Human Pancreatic Islets

    Kaur, S., Mirza, A. H. & Pociot, Flemming, 2018, In: Non-coding RNA. 4, 4, 20 p., 38.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Changes in the lipidome in type 1 diabetes following low carbohydrate diet: Post-hoc analysis of a randomized crossover trial

    Al-Sari, N., Schmidt, S., Suvitaival, T., Kim, M., Trošt, K., Ranjan, A. G., Christensen, M. B., Overgaard, A. J., Pociot, Flemming, Nørgaard, Kirsten & Legido-Quigley, C., 2021, In: Endocrinology, Diabetes and Metabolism. 4, 2, e00213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Characterization of plasma lipidomics in adolescent subjects with increased risk for type 1 diabetes in the DiPiS cohort

    Andersson Svärd, A., Kaur, S., Trôst, K., Suvitaival, T., Lernmark, Å., Maziarz, M., Pociot, Flemming, Overgaard, A. J. & DiPiS Study Group, D. S. G., 2020, In: Metabolomics : Official journal of the Metabolomic Society. 16, 10, 14 p., 10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Characterization of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC-βH5 beta cells

    Frørup, C., Gerwig, R., Svane, C. A. S., Mendes Lopes de Melo, J., Henriksen, K., Fløyel, T., Pociot, Flemming, Kaur, S. & Størling, Joachim, 2023, In: Frontiers in Endocrinology. 14, 15 p., 1128523.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Children at onset of type 1 diabetes show altered N-glycosylation of plasma proteins and IgG

    Rudman, N., Kifer, D., Kaur, S., Simunović, V., Cvetko, A., Pociot, Flemming, Morahan, G. & Gornik, O., 2022, In: Diabetologia. 65, 8, p. 1315-1327 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes

    Wegeberg, A. L., Okdahl, T., Fløyel, T., Brock, C., Ejskjaer, N., Riahi, S., Pociot, Flemming, Størling, Joachim & Brock, Birgitte, 2020, In: Mediators of Inflammation. 2020, 10 p., 3590389.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Circulating MicroRNAs in Plasma of Hepatitis B e Antigen Positive Children Reveal Liver-Specific Target Genes

    Winther, T. N., Jacobsen, K. S., Mirza, A. H., Heiberg, I. L., Bang-Berthelsen, C. H., Pociot, Flemming & Høgh, Birthe, 2014, In: International Journal of Hepatology. 2014, p. 791045

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Circulating microRNA levels predict residual beta cell function and glycaemic control in children with type 1 diabetes mellitus

    Samandari, N., Mirza, A. H., Nielsen, L. B., Kaur, S., Hougaard, P., Fredheim, S., Mortensen, H. B. & Pociot, Flemming, 2017, In: Diabetologia. 60, 2, p. 354-363

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Cross-species high-resolution transcriptome profiling suggests biomarkers and therapeutic targets for ulcerative colitis

    Yarani, R., Palasca, Oana, Doncheva, Nadezhda Tsankova, Anthon, Christian, Pilecki, B., Svane, C. A. S., Mirza, A. H., Litman, Thomas, Holmskov, U., Bang-Berthelsen, C. H., Vilien, M., Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2023, In: Frontiers in Molecular Biosciences. 9, 1081176.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Decreased markers of bone turnover in children and adolescents with type 1 diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Jørgensen, Niklas Rye, Olsen, B. S., Pociot, Flemming & Johannesen, Jesper, 2020, In: Pediatric Diabetes. 21, 3, p. 505-514

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Diabetes complications and extracellular vesicle therapy

    Soltani, S., Mansouri, K., Parvaneh, S., Thakor, A. S., Pociot, Flemming & Yarani, R., 2022, In: Reviews in Endocrine and Metabolic Disorders. 23, p. 357–385

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Differences in insulin sensitivity in the partial remission phase of childhood type 1 diabetes: a longitudinal cohort study

    Mørk, F. C. B., Madsen, J. O. B., Jensen, Andreas Kryger, van Hall, Gerrit, Pilgaard, Kasper Ascanius, Pociot, Flemming & Johannesen, Jesper, 2022, In: Diabetic Medicine. 39, 2, 9 p., 14702.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Differential plasma microRNA profiles in HBeAg positive and HBeAg negative children with chronic hepatitis B

    Winther, T. N., Bang-Berthelsen, C. H., Heiberg, I. L., Pociot, Flemming & Høgh, Birthe, 2013, In: PLOS ONE. 8, 3, p. e58236

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Differentially Expressed miRNAs in Ulcerative Colitis and Crohn's Disease

    Yarani, R., Shojaeian, A., Palasca, Oana, Doncheva, Nadezhda Tsankova, Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2022, In: Frontiers in Immunology. 13, 21 p., 865777.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic ß cell fate in response to cytokines

    Hansen, J. B., Tonnesen, M. F., Madsen, A. N., Hagedorn, P., Friberg, J., Grunnet, L. G., Heller, R. S., Nielsen, A. Ø., Størling, J., Baeyens, L., Anker-Kitai, L., Qvortrup, K., Bouwens, L., Efrat, S., Aalund, M., Andrews, N. C., Billestrup, N., Karlsen, A. E., Holst, B., Pociot, F. & 1 others, Mandrup-Poulsen, Thomas, 2012, In: Cell Metabolism. 16, 4, p. 449-61 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Does rapid sequence divergence preclude RNA structure conservation in vertebrates?

    Seemann, Ernst Stefan, Mirza, A. H., Bang-Berthelsen, C. H., Garde, C., Christensen-Dalsgaard, M., Workman, C. T., Pociot, Flemming, Tommerup, Niels, Gorodkin, Jan & Ruzzo, W. L., 2022, In: Nucleic Acids Research. 50, 5, p. 2452-2463 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Effects of the genome on immune regulation in type 1 diabetes

    Pociot, Flemming, Kaur, S. & Nielsen, L. B., Jul 2016, In: Pediatric Diabetes. 17 , S22, p. 37-42 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Elevated levels of interleukin-12/23p40 may serve as a potential indicator of dysfunctional heart rate variability in type 2 diabetes

    Wegeberg, A. M., Okdahl, T., Riahi, S., Ejskjaer, N., Pociot, Flemming, Størling, Joachim, Brock, Birgitte & Brock, C., 2022, In: Cardiovascular Diabetology. 21, 1, 10 p., 5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Expression profiling of human genetic and protein interaction networks in type 1 diabetes

    Bergholdt, R., Brorsson, C., Lage, K., Nielsen, Jens Høiriis, Brunak, S. & Pociot, Flemming, 2009, In: PLoS ONE. 4, 7, p. e6250

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Extracellular Vesicle Therapy for Type 1 Diabetes

    Soltani, S., Mansouri, K., Emami Aleagha, M. S., Moasefi, N., Yavari, Niloofar, Shakouri, S. K., Notararigo, S., Shojaeian, A., Pociot, Flemming & Yarani, R., 2022, In: Frontiers in Immunology. 13, 865782.

    Research output: Contribution to journalReviewResearchpeer-review

  47. Published

    Finding diabetic nephropathy biomarkers in the plasma peptidome by high-throughput magnetic bead processing and MALDI-TOF-MS analysis

    Hansen, H. G., Overgaard, J., Lajer, M., Hubalek, F., Højrup, P., Pedersen, L., Tarnow, L., Rossing, Peter, Pociot, Flemming & McGuire, J. N., 1 Sep 2010, In: Proteomics - Clinical Applications. 4, 8-9, p. 697-705 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes

    Robertson, C. C. & Type 1 Diabetes Genetics Consortium, T. 1. D. G. C., 2021, In: Nature Genetics. 53, 7, p. 962-971 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Functional SOCS1 polymorphisms are associated with variation in obesity in whites

    Gylvin, T., Ek, J., Nolsøe, R., Albrechtsen, A., Andersen, G., Bergholdt, R., Brorsson, C., Bang-Berthelsen, C. H., Hansen, T., Karlsen, A. E., Billestrup, N., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye, Mandrup-Poulsen, Thomas, Nerup, J. & Pociot, Flemming, 2009, In: Diabetes, Obesity and Metabolism. 11, 3, p. 196-203 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Functional promoter haplotypes of the human FAS gene are associated with the phenotype of SLE characterized by thrombocytopenia

    Nolsøe, R. L., Kelly, J. A., Pociot, Flemming, Moser, K., Kristiansen, O. P., Mandrup-Poulsen, Thomas & Harley, J. B., 1 Dec 2005, In: Genes and Immunity. 6, 8, p. 699-706 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY)

    Boesgaard, T. W., Pruhova, S., Andersson, E. A., Cinek, O., Obermannova, B., Lauenborg, J., Damm, Peter, Bergholdt, R., Pociot, Flemming, Pisinger, C., Barbetti, F., Lebl, J., Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2010, In: B M C Medical Genetics. 11, p. 42

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    GLP-1 Induces Barrier Protective Expression in Brunner's Glands and Regulates Colonic Inflammation

    Bang-Berthelsen, C. H., Holm, T. L., Pyke, C., Simonsen, L., Søkilde, R., Pociot, Flemming, Heller, R. S., Folkersen, L., Kvist, P. H., Jackerott, M., Fleckner, J., Vilien, M., Knudsen, L. B., Heding, A. & Frederiksen, K. S., Sep 2016, In: Inflammatory Bowel Diseases. 22, 9, p. 2078-97 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Gene expression signature predicts rate of type 1 diabetes progression

    Suomi, T., Starskaia, I., Kalim, U. U., Rasool, O., Jaakkola, M. K., Grönroos, T., Välikangas, T., Brorsson, C., Mazzoni, G., Bruggraber, S., Overbergh, L., Dunger, D., Peakman, M., Chmura, P., Brunak, S., Schulte, A. M., Mathieu, C., Knip, M., Lahesmaa, R., Elo, L. L. & 4 others, Pociot, Flemming, Johannesen, Jesper, Rossing, Peter & INNODIA consortium, I. C., 2023, In: EBioMedicine. 92, 18 p., 104625.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Genes affecting β-cell function in type 1 diabetes

    Fløyel, T., Kaur, S. & Pociot, Flemming, Nov 2015, In: Current Diabetes Reports. 15, 11, p. 1-11 15-97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Genetic Determinants of Enterovirus Infections: Polymorphisms in Type 1 Diabetes and Innate Immune Genes in the MIDIA Study

    Witsø, E., Cinek, O., Tapia, G., Brorsson, C. A., Stene, L. C., Gjessing, H. K., Rasmussen, T., Bergholdt, R., Pociot, Flemming & Rønningen, K. S., Dec 2015, In: Viral Immunology. 28, 10, p. 556-63 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control

    Brorsson, C. A., Nielsen, L. B., Andersen, M., Kaur, S., Bergholdt, R., Hansen, L., Mortensen, H. B., Pociot, Flemming, Størling, J. & Hvidoere Study Group On Childhood Diabetes, H. S. G. O. C. D., 2016, In: Journal of Diabetes Research. 2016, 8 p., 9570424.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Genetic Variants Associated with Neuropeptide Y Autoantibody Levels in Newly Diagnosed Individuals with Type 1 Diabetes

    Mansachs, S. J., Villumsen, S. O., Johannesen, Jesper, Lind, A., Kaur, S. & Pociot, Flemming, 2022, In: Genes. 13, 5, 869.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Genetic association study in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) identifies several potential risk loci

    Hajdarevic, R., Lande, A., Mehlsen, J., Rydland, A., Sosa, D. D., Strand, E. B., Mella, O., Pociot, Flemming, Fluge, Ø., Lie, B. A. & Viken, M. K., 2022, In: Brain, Behavior, and Immunity. 102, p. 362-369 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity

    Pedersen, K., Haupt-Jorgensen, M., Krogvold, L., Kaur, S., Gerling, I. C., Pociot, Flemming, Dahl-Jørgensen, K. & Buschard, K., Aug 2021, In: Diabetologia. 64, 8, p. 1805-1815 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Genetic risk factors for type 1 diabetes

    Pociot, Flemming & Lernmark, Å., Jun 2016, In: The Lancet. 387, 10035, p. 2331-9 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  61. Genetic versus Non-Genetic Regulation of miR-103, miR-143 and miR-483-3p Expression in Adipose Tissue and Their Metabolic Implications-A Twin Study

    Bork-Jensen, J., Thuesen, A. C. B., Bang-Bertelsen, C. H., Grunnet, Louise Groth, Pociot, Flemming, Beck-Nielsen, H., Ozanne, S. E., Poulsen, P. & Vaag, A., 2014, In: Genes. 5, 3, p. 508-17 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

    Barrett, J. C., Clayton, D. G., Concannon, P., Akolkar, B., Cooper, J. D., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., Nierras, C., Plagnol, V., Pociot, Flemming, Schuilenburg, H., Smyth, D. J., Stevens, H., Todd, J. A., Walker, N. M., Rich, S. S. & The Type 1 Diabetes Genetics Consortium, T. T. 1. D. G. C., 2009, In: Nature Genetics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Genome-wide scan for linkage to type 1 diabetes in 2,496 multiplex families from the type 1 diabetes genetics consortium

    Concannon, P., Chen, W. M., Julier, C., Morahan, G., Akolkar, B., Erlich, H. A., Hilner, J. E., Nerup, J., Nierras, C., Pociot, Flemming, Todd, J. A. & Rich, S. S., 2009, In: Diabetes. 58, 4, p. 1018-1022 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Hepatitis B surface antigen quantity positively correlates with plasma levels of microRNAs differentially expressed in immunological phases of chronic hepatitis B in children

    Winther, T. N., Heiberg, I. L., Bang-Berthelsen, C. H., Pociot, Flemming & Høgh, Birthe, 2013, In: PLoS ONE. 8, 11, p. e80384

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Hepatitis B virus suppresses the secretion of insulin-like growth factor binding protein 1 to facilitate anti-apoptotic IGF-1 effects in HepG2 cells

    Nielsen, K. O., Mirza, A. H., Kaur, S., Jacobsen, K. S., Winther, T. N., Glebe, D., Pociot, Flemming, Høgh, Birthe & Størling, J., 15 Sep 2018, In: Experimental Cell Research. 370, 2, p. 399-408 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Hepatitis B virus upregulates host microRNAs that target apoptosis-regulatory genes in an in vitro cell model

    Nielsen, K. O., Jacobsen, K. S., Mirza, A. H., Winther, T. N., Størling, J., Glebe, D., Pociot, Flemming & Høgh, Birthe, 2018, In: Experimental Cell Research. 371, 1, p. 92-103

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    High neonatal blood iron content is associated with the risk of childhood type 1 diabetes mellitus

    Kyvsgaard, J. N., Overgaard, A. J., Thorsen, S. U., Hansen, Thomas Hesselhøj, Pipper, C. B., Mortensen, H. B., Pociot, Flemming & Svensson, Jannet, 2017, In: Nutrients. 9, 11, 10 p., 1221.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    High-Throughput Human Complement C3 N-Glycoprofiling Identifies Markers of Early Onset Type 1 Diabetes Mellitus in Children

    Šoić, D., Keser, T., Štambuk, J., Kifer, D., Pociot, Flemming, Lauc, G., Morahan, G., Novokmet, M. & Gornik, O., 2022, In: Molecular and Cellular Proteomics. 21, 10, 100407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Home capillary sampling and screening for type 1 diabetes, celiac disease, and autoimmune thyroid disease in a Swedish general pediatric population: the TRIAD study

    Naredi Scherman, M., Lind, A., Hamdan, S., Lundgren, M., Svensson, J., Pociot, Flemming & Agardh, D., 2024, In: Frontiers in Pediatrics. 12, 10 p., 1386513.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Human pathways in animal models: possibilities and limitations

    Doncheva, Nadezhda Tsankova, Palasca, Oana, Yarani, R., Litman, Thomas, Anthon, Christian, Groenen, M. A. M., Stadler, P. F., Pociot, Flemming, Jensen, Lars Juhl & Gorodkin, Jan, 2021, In: Nucleic Acids Research. 49, 4, p. 1859-1871 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis

    Berchtold, L. A., Størling, Z. M., Ortis, F., Lage, K., Bang-Berthelsen, C., Bergholdt, R., Hald, J., Brorsson, C. A., Eizirik, D. L., Pociot, Flemming, Brunak, Søren & Størling, Joachim, 2011, In: PNAS Early Edition. 108, 37, p. E681-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Hypoglycemia, S-ACE and ACE genotypes in a Danish nationwide population of children and adolescents with type 1 diabetes

    Johannesen, Jesper, Svensson, Jannet, Bergholdt, R., Eising, S., Gramstrup, H., Frandsen, E., Dick-Nielsen, J., Hansen, L., Pociot, Flemming, Mortensen, H. B. & Danish Society for Diabetes in Childhood and Adolescence, D. S. F. D. I. C. A. A., Mar 2011, In: Pediatric Diabetes Online. 12, 2, p. 100-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Identification of T1D susceptibility genes within the MHC region by combining protein interaction networks and SNP genotyping data

    Brorsson, C., Hansen, N. T., Lage, K., Bergholdt, R., Brunak, Søren, Pociot, Flemming & Diabetes Genetics Consortium, D. G. C., Feb 2009, In: Diabetes, Obesity and Metabolism Online. 11, SUPPL. 1, p. 60-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Identification of a type 1 diabetes-associated CD4 promoter haplotype with high constitutive activity

    Kristiansen, O. P., Karlsen, A. E., Larsen, Z. M., Johannesen, Jesper, Pociot, Flemming, Mandrup-Poulsen, Thomas & Danish IDDM Epidemiology and Genetics Group and Danish Study Group of IDDM in Childhood, D. I. E. A. G. G. A. D. S. G. O. I. I. C., 1 Jun 2004, In: Scandinavian Journal of Immunology. 59, 6, p. 582-91 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Identification of valid reference genes for microRNA expression studies in a hepatitis B virus replicating liver cell line

    Jacobsen, K. S., Nielsen, K. O., Nordmann Winther, T., Glebe, D., Pociot, Flemming & Høgh, Birthe, 22 Jan 2016, In: BMC Research Notes. 9, p. 1-7 7 p., 38.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Increased levels of inflammatory factors are associated with severity of polyneuropathy in type 1 diabetes

    Okdahl, T., Brock, C., Floyel, T., Wegeberg, A. L., Jakobsen, P. E., Ejskjaer, N., Pociot, Flemming, Brock, Birgitte & Størling, Joachim, 2020, In: Clinical Endocrinology. 93, 4, p. 419-428

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Increased mortality in a Danish cohort of young people with Type 1 diabetes mellitus followed for 24 years

    Sandahl, K., Nielsen, L. B., Svensson, Jannet, Johannesen, Jesper, Pociot, Flemming, Mortensen, H. B., Hougaard, P., Broe, R., Rasmussen, M. L., Grauslund, J., Peto, T. & Olsen, B. S., Mar 2017, In: Diabetic Medicine. 34, 3, p. 380–386

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Influence of Disease Duration on Circulating Levels of miRNAs in Children and Adolescents with New Onset Type 1 Diabetes

    Samandari, N., Mirza, A. H., Kaur, S., Hougaard, P., Nielsen, L. B., Fredheim, S., Mortensen, H. B. & Pociot, Flemming, 2018, In: Non-coding RNA. 4, 4, 12 p., 35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Integrated glycomics and genetics analyses reveal a potential role for N-glycosylation of plasma proteins and IgGs, as well as the complement system, in the development of type 1 diabetes

    Rudman, N., Kaur, S., Simunović, V., Kifer, D., Šoić, D., Keser, T., Štambuk, T., Klarić, L., Pociot, Flemming, Morahan, G. & Gornik, O., 2023, In: Diabetologia. 66, 6, p. 1071-1083 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Integrative analysis for finding genes and networks involved in diabetes and other complex diseases

    Bergholdt, R., Størling, Z. M., Lage, K., Karlberg, E. O., Olason, P. I., Aalund, M., Nerup, J., Brunak, Søren, Workman, C. & Pociot, Flemming, 2007, In: Genome Biology (Online Edition). 8, 11, p. R253

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Levels of soluble TREM-1 in children with newly diagnosed type 1 diabetes and their siblings without type 1 diabetes: a Danish case-control study

    Thorsen, S. U., Pipper, C. B., Mortensen, H. B., Skogstrand, K., Pociot, Flemming, Johannesen, Jesper, Svensson, Jannet & the Danish Childhood Diabetes Register, T. D. C. D. R., Dec 2017, In: Pediatric Diabetes. 18, 8, p. 749–754

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining

    Kirk, I. K., Simon, C., Banasik, K., Holm, P. C., Haue, A. D., Jensen, P. B., Jensen, L. J., Rodriguez, C. L., Pedersen, M. K., Eriksson, R., Andersen, H. U., Almdal, T., Bork-Jensen, J., Grarup, N., Borch-Johnsen, K., Pedersen, O., Pociot, F., Hansen, T., Bergholdt, R., Rossing, P. & 1 others, Brunak, Søren, 2019, In: eLife. 8, 19 p., e44941.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Lipidomic and metabolomic characterization of a genetically modified mouse model of the early stages of human type 1 diabetes pathogenesis

    Overgaard, A. J., Weir, J. M., De Souza, D. P., Tull, D., Haase, C., Meikle, P. J. & Pociot, Flemming, Jan 2016, In: Metabolomics. 12, p. 1-9 9 p., 13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Lipidomics of human adipose tissue reveals diversity between body areas

    Al-Sari, N., Suvitaival, T., Mattila, I., Ali, A., Ahonen, L., Trost, K., Henriksen, T. F., Pociot, Flemming, Dragsted, Lars Ove & Legido-Quigley, C., 2020, In: P L o S One. 15, 6, 15 p., e0228521.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Long Noncoding RNAs in Diabetes and β-Cell Regulation

    Kaur, S., Frørup, C., Jensen, V. H., Mirza, A. H., de Melo, J. M. L., Yarani, R., Overgaard, A. J., Størling, J. & Pociot, Flemming, 2020, The Chemical Biology of Long Noncoding RNAs: RNA Technologies. Jurga, S. & Barciszewski, J. (eds.). Springer, Vol. 11. p. 523-544

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  86. Published

    Long non-coding RNAs as novel players in β cell function and type 1 diabetes

    Mirza, A. H., Kaur, S. & Pociot, Flemming, 24 Jul 2017, In: Human Genomics (Online). 11, 10 p., 17.

    Research output: Contribution to journalReviewResearchpeer-review

  87. Published

    Low perinatal zinc status is not associated with the risk of type 1 diabetes in children

    Kyvsgaard, J. N., Overgaard, A. J., Jacobsen, L. D., Thorsen, S. U., Pipper, C. B., Hansen, Thomas Hesselhøj, Husted, Søren, Mortensen, H. B., Pociot, Flemming & Svensson, Jannet, 2017, In: Pediatric Diabetes. 18, 7, p. 637–642 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Low-grade inflammation in type 2 diabetes: A cross-sectional study from a Danish diabetes outpatient clinic

    Okdahl, T., Wegeberg, A. M., Pociot, Flemming, Brock, Birgitte, Størling, Joachim & Brock, C., 2022, In: BMJ Open. 12, 12, 10 p., e062188.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Mass spectrometry is only one piece of the puzzle in clinical proteomics

    McGuire, J. N., Overgaard, J. & Pociot, Flemming, 2008, In: Briefings in Functional Genomics and Proteomics. 7, 1, p. 74-83 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Metabolomic Biomarkers in the Progression to Type 1 Diabetes

    Overgaard, A. J., Kaur, S. & Pociot, Flemming, Dec 2016, In: Current Diabetes Reports. 16, 5 p., 127.

    Research output: Contribution to journalReviewResearchpeer-review

  91. Published

    MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage

    Vestergaard, A. L., Bang-Berthelsen, C. H., Floyel, T., Stahl, J. L., Christen, L., Sotudeh, F. T., Horskjaer, P. D. H., Frederiksen, K. S., Kofod, F. G., Bruun, C., Berchtold, L. A., Storling, J., Regazzi, R., Kaur, S., Pociot, Flemming & Mandrup-Poulsen, Thomas, 27 Sep 2018, In: PLOS ONE. 13, 9, p. 1-22 22 p., e0203713 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    MicroRNAs as regulators of beta-cell function and dysfunction

    Osmai, M., Osmai, Y., Bang-Berthelsen, C. H., Pallesen, E. M. H., Vestergaard, A. L., Novotny, G. W., Pociot, Flemming & Mandrup-Poulsen, Thomas, May 2016, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 32, 4, p. 334–349 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity

    Gylvin, T., Nolsøe, R., Hansen, Torben, Nielsen, E. M. D., Bergholdt, R., Karlsen, A. E., Billestrup, Nils, Borch-Johnsen, K., Pedersen, O., Mandrup-Poulsen, Thomas, Nerup, J. & Pociot, Flemming, 1 Jul 2004, In: Diabetologia. 47, 7, p. 1273-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Neonatal levels of adiponectin, interleukin-10 and interleukin-12 are associated with the risk of developing type 1 diabetes in childhood and adolescence: A nationwide Danish case-control study

    Thorsen, S. U., Pipper, C. B., Eising, S., Skogstrand, K., Hougaard, D. M., Svensson, Jannet & Pociot, Flemming, Jan 2017, In: Clinical Immunology. 174, p. 18–23 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Neonatal vitamin D status is not associated with later risk of type 1 diabetes: results from two large Danish population-based studies

    Jacobsen, Ramune, Thorsen, S. U., Cohen, A. S., Lundqvist, M., Frederiksen, P., Pipper, C. B., Pociot, Flemming, Thygesen, L. C., Ascherio, A., Svensson, Jannet & Heitmann, Berit, Sep 2016, In: Diabetologia. 59, 9, p. 1871-1881 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    No Contribution of GAD-65 and IA-2 Autoantibodies around Time of Diagnosis to the Increasing Incidence of Juvenile Type 1 Diabetes: A 9-Year Nationwide Danish Study

    Thorsen, S. U., Pipper, C. B., Mortensen, H. B., Pociot, Flemming, Johannesen, Jesper & Svensson, Jannet, 2016, In: International Journal of Endocrinology. 2016, 7 p., 8350158.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    No association between type 1 diabetes and genetic variation in vitamin D metabolism genes: a Danish study

    Thorsen, S. U., Mortensen, H. B., Carstensen, Bendix, Fenger, M., Thuesen, B. H., Husemoen, L., Bergholdt, R., Brorsson, C., Pociot, Flemming, Linneberg, Allan René & Svensson, Jannet, Sep 2014, In: Pediatric Diabetes. 15, 6, p. 416-421 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    No association of the IRS1 and PAX4 genes with type I diabetes

    Bergholdt, R., Brorsson, C., Boehm, B., Morahan, G. & Pociot, Flemming, 2009, In: Genes and Immunity. 10, p. S49-S53 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    No difference in vitamin d levels between children newly diagnosed with type 1 diabetes and their healthy siblings

    Thorsen, S. U., Mortensen, H. B., Carstensen, Bendix, Fenger, M., Thuesen, B. H., Husemoen, L. L., Bergholdt, R., Brorsson, C., Pociot, Flemming, Linneberg, Allan René & Svensson, Jannet, 2013, In: Diabetes Care. 36, 9, p. e157-e158

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes

    Brorsson, C. A., Onengut, S., Chen, W., Wenzlau, J., Yu, L., Baker, P., Williams, A. J. K., Bingley, P. J., Hutton, J. C., Eisenbarth, G. S., Concannon, P., Rich, S. S., Pociot, Flemming & Type 1 Diabetes Genetics Consortium, T. 1. D. G. C., Aug 2015, In: Diabetes. 64, 8, p. 3017-27 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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