David Paul Drucker Woldbye

David Paul Drucker Woldbye

Associate Professor


  1. Published

    The dorsomedial hypothalamus and nucleus of the solitary tract as key regulators in a rat model of chronic obesity

    Zhang, C., Barkholt, P., Nielsen, J. C., Thorbek, D. D., Rigbolt, K., Vrang, N., Woldbye, David Paul Drucker & Jelsing, J., 2020, In: Brain Research. 1727, 146538.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    A Peptide Antagonist of ErbB Receptors, Inherbin3, Induces Neurite Outgrowth from Rat Cerebellar Granule Neurons Through ErbB1 Inhibition

    Xu, R., Pankratova, Stanislava, Christiansen, S. H. O., Woldbye, David Paul Drucker, Højland, A., Bock, E. M. & Berezin, V., 2013, In: Neurochemical Research. 38, 12, p. 2550-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures

    Woldbye, David Paul Drucker, Ängehagen, M., Gøtzsche, C. R., Elbrønd-Bek, H., Sørensen, Andreas Toft, Christiansen, S. H. O., Olesen, M. V., Nikitidou, L., Hansen, T. V. O., Kanter-Schlifke, I. & Kokaia, M., Sep 2010, In: Brain. 133, 9, p. 2778-88 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Antiepileptic effects of NPY on pentylenetetrazole seizures

    Woldbye, David Paul Drucker, 1998, In: Regulatory Peptides. 75-76, p. 279-282

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Powerful inhibition of kainic acid seizures by neuropeptide Y via Y5-like receptors

    Woldbye, David Paul Drucker, Larsen, P. J., Mikkelsen, J. D., Klemp, K., Madsen, T. M. & Bolwig, T. G., 1997, In: Nature Medicine. 3, 7, p. 761-764

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Neuropeptide Y Attenuates Naloxone-Precipitated Morphine Withdrawal via Y5-like Receptors

    Woldbye, David Paul Drucker, Klemp, K. & Madsen, T. M., 1998, In: Journal of Pharmacology and Experimental Therapeutics. 284, no. 2, p. 633-636

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Neuropeptide Y

    Woldbye, David Paul Drucker, 2002, In: Molekulyarnaya Meditsina. 5, p. 2246-50

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Ethanol withdrawal in rats is attenuated by intracerebroventricular administration of neuropeptide Y

    Woldbye, David Paul Drucker, Ulrichsen, J., Haugbøl, S. & Bolwig, T. G., 2002, In: Alcohol & Alcoholism. 37(4), p. 318-21

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Neuropeptide Y inhibits in vitro epileptiform activity in the entorhinal cortex of mice

    Woldbye, David Paul Drucker, Nanobashvili, A., Husum, H., Bolwig, T. G. & Kokaia, M., 2002, In: Neurosc. Lett.. 333, 2, p. 127-30

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Neuropeptide Y and seizures: effects of exogenously applied ligands

    Woldbye, David Paul Drucker & Kokaia, M., 2004, In: Neuropeptides. Vol. 38, no.4, p. 253-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The how and Y of eating

    Woldbye, David Paul Drucker & Larsen, P. J., 1998, In: Nature Medicine. Vol 4, No 6, p. 671-672

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors

    Woldbye, David Paul Drucker, Nanobashvili, A., Sørensen, Andreas Toft, Husum, H., Bolwig, T. G., Sørensen, G., Ernfors, P., Kokaia, M. & Sørensen, G., 1 Dec 2005, In: Neurobiology of Disease. 20, 3, p. 760-72 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Synaptic degeneration and remodelling after fast kindling of the olfactory bulb.

    Woldbye, David Paul Drucker, Bolwig, T. G., Kragh, J. & Jørgensen, O. S., 1996, In: Neurochemical Research. 21, 5, p. 585-93 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Prolonged induction of c-fos in neuropeptide Y- and somatostatin-immunoreactive neurons of the rat dentate gyrus after electroconvulsive stimulation.

    Woldbye, David Paul Drucker, Greisen, M. H., Bolwig, T. G., Larsen, Jacob & Mikkelsen, J. D., 1996, In: Brain Research. 720, 1-2, p. 111-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Neuropeptide Y inhibits hippocampal seizures and wet dog shakes.

    Woldbye, David Paul Drucker, Madsen, T. M., Larsen, Jacob, Mikkelsen, J. D. & Bolwig, T. G., 1996, In: Brain Research. 737, 1-2, p. 162-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Inhibition of epileptiform activity by neuropeptide Y in brain tissue from drug-resistant temporal lobe epilepsy patients

    Wickham, J., Ledri, M., Bengzon, J., Jespersen, B., Pinborg, Lars Hageman, Englund, E., Woldbye, David Paul Drucker, Andersson, M. & Kokaia, M., 2019, In: Scientific Reports. 9, 11 p., 19393.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Prolonged life of human acute hippocampal slices from temporal lobe epilepsy surgery

    Wickham, J., Brödjegård, N. G., Vighagen, R., Pinborg, Lars Hageman, Bengzon, J., Woldbye, David Paul Drucker, Kokaia, M. & Andersson, M., 2018, In: Scientific Reports. 8, 13 p., 4158.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Neuropeptide Y genes and suicidal behaviour among schizophrenic patients

    Wang, August Gabriel, Koefoed, P., Jacoby, A. S., Woldbye, David Paul Drucker, Rasmussen, Henrik Berg, Timm, S., Dam, H., Jakobsen, K. D., Nordentoft, Merete, Jürgens, Gesche, Sorensen, H. J., Garsdal, O., Hvid, M. & Werge, Thomas, Jun 2013, In: Psychiatric Genetics. 23, 3, p. 139-40 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Electrical amygdala kindling in alcohol-withdrawal kindled rats

    Ulrichsen, J., Woldbye, David Paul Drucker, Madsen, T. M., Clemmesen, L., Haugbøl, S., Olsen, C. H., Laursen, H., Bolwig, T. G. & Hemmingsen, R., 1998, In: Alcohol & Alcoholism. 33, 3, p. 244-254

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    No Loss of somatostatin-immunoreactive neurons in the hippocampal dentate hilus of alcohol-withdrawal kindled rats

    Ulrichsen, J., Woldbye, David Paul Drucker, Olsen, C. H., Haugbøl, S., Bolwig, T. G. & Hemmingsen, R., 1996, In: Alcohol & Alcoholism. 31, 4, p. 411-419

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Sustained overexpression of neuropeptide S in the amygdala reduces anxiety-like behavior in rats

    Tillmann, S., Skibdal, H. E., Christiansen, S. H., Gøtzsche, C. R., Hassan, M., Mathe, A. A., Wegener, G. & Woldbye, David Paul Drucker, 2019, In: Behavioural Brain Research. 367, p. 28-34 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Can gene therapy treat anxiety? Overexpression of Neuropeptide S using adeno-associated viral vectors

    Tillmann, S., Elbrond-Bek, H., Gotzsche, C. R., Christiansen, S. H., Mathe, A. A., Woldbye, David Paul Drucker & Wegener, G., Jun 2016, In: International Journal of Neuropsychopharmacology. 19, S1, p. 52-53

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  23. Published

    Reduced cocaine self-administration in muscarinic M5 acetylcholine receptor-deficient mice

    Thomsen, M. M., Woldbye, David Paul Drucker, Wörtwein, Gitta, Fink-Jensen, A., Wess, J. & Caine, S. B., 2005, In: Journal of Neuroscience. Vol. 25, p. 8141-49

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Involvement of Y5 receptors in neuropeptide Y agonist-induced analgesic-like effect in the rat hot plate test

    Thomsen, M., Wörtwein, Gitta, Olesen, M. V., Begtrup, M., Havez, S., Bolwig, T. G. & Woldbye, David Paul Drucker, 2007, In: Brain Research. 1155, p. 49-55

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Effects of acute and chronic aripiprazole treatment on choice between cocaine self-administration and food under a concurrent schedule of reinforcement in rats

    Thomsen, M., Fink-Jensen, Anders, Woldbye, David Paul Drucker, Wörtwein, Gitta, Sager, T., Holm, R., Pepe, L. & Barak Caine, S., 2008, In: Psychopharmacology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Decreased prepulse inhibition and increased sensitivity to muscarinic, but not dopaminergic drugs in M-5 muscarinic acetylcholine receptor knockout mice

    Thomsen, M., Wortwein, G., Fink-Jensen, Anders, Woldbye, David Paul Drucker, Wess, J. & Caine, S. B., 2007, In: Psychopharmacology. 192, 1, p. 97-110 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Differential roles for neuropeptide Y Y1 and Y5 receptors in anxiety and sedation

    Sørensen, G., Lindberg, C., Wörtwein, Gitta, Bolwig, T. G., Woldbye, David Paul Drucker & Sørensen, G., 1 Sep 2004, In: Journal of Neuroscience Research. 77, 5, p. 723-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Aripiprazole blocks acute self-administration of cocaine and is not self-administered in mice

    Sørensen, G., Sager, T. N., Petersen, Jørgen Holm, Brennum, L. T., Thøgersen, P., Hee Bengtsen, C., Thomsen, M., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, 2008, In: Psychopharmacology. 199, 1, p. 37-46 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Neuropeptide Y infusion into the shell region of the rat nucleus accumbens increases extracellular levels of dopamine

    Sørensen, G., Wegener, G., Hasselstrøm, J., Hansen, T. V. O., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, 2009, In: NeuroReport. 20, 11, p. 1023-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Mice lacking neuropeptide Y show increased sensitivity to cocaine

    Sørensen, G. & Woldbye, David Paul Drucker, 2012, In: Synapse. 66, p. 840-3 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Neuropeptide Y Y5 receptor antagonism causes faster extinction and attenuates reinstatement in cocaine-induced place preference

    Sørensen, G., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, Apr 2013, In: Pharmacology, Biochemistry and Behavior. 105, p. 151-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Addiction-Related Effects of DOV 216,303 and Cocaine: A Comparative Study in the Mouse

    Sørensen, G., Husum, H., Brennum, L. T., Bundgaard, C., Montezinho, L. C. P., Mørk, A., Wörtwein, Gitta & Woldbye, David Paul Drucker, Jun 2014, In: Basic & Clinical Pharmacology & Toxicology. 114, 6, p. 451-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation

    Sørensen, G., Rickhag, Karl Mattias, Leo, D., Lycas, M. D., Ridderstrøm, P. H., Weikop, P., Lilja, J. H., Rifes, P., Herborg, Freja, Woldbye, David Paul Drucker, Wörtwein, Gitta, Gainetdinov, R. R., Fink-Jensen, Anders & Gether, Ulrik, 2021, In: Journal of Biological Chemistry. 297, 6, 101361.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Neuropeptide Y Y5 receptor antagonism attenuates cocaine-induced effects in mice.

    Sørensen, G., Jensen, M., Weikop, Pia, Nielsen, D. D., Christiansen, S. H. O., Loland, Claus Juul, Bengtsen, C. H., Petersen, Jørgen Holm, Fink-Jensen, Anders, Wörtwein, Gitta & Woldbye, David Paul Drucker, Feb 2012, In: Psychopharmacology. 222, p. 565-577 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Gene Therapy Vector Encoding Neuropeptide Y and Its Receptor Y2 for Future Treatment of Epilepsy: Preclinical Data in Rats

    Szczygiel, Julia Alicja, Danielsen, K. I., Melin, E., Rosenkranz, S. H., Pankratova, Stanislava, Ericsson, A., Agerman, K., Kokaia, M. & Woldbye, David Paul Drucker, 2020, In: Frontiers in Molecular Neuroscience. 13, 13 p., 232.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    α-Synuclein Overexpression Increases Dopamine D2/3 Receptor Binding and Immune Activation in a Model of Early Parkinson's Disease

    Stokholm, K., Thomsen, M. B., Phan, J., Moller, L. K., Bay-Richter, C., Christiansen, S. H., Woldbye, David Paul Drucker, Romero-Ramos, M. & Landau, A. M., 2021, In: Biomedicines. 9, 12, 16 p., 1876.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The C-terminal flanking peptide of neuropeptide Y (NPY) is not essential for seizure-suppressant actions of prepro-NPY overexpression in male rats

    Soud, K., Jørgensen, Søren Heide, Woldbye, David Paul Drucker & Sørensen, Andreas Toft, 2019, In: Journal of Neuroscience Research. 97, 3, p. 362-372 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Exploring the Behavioral and Metabolic Phenotype Generated by Re-Introduction of the Ghrelin Receptor in the Ventral Tegmental Area

    Skov, Louise Julie, Jensen, M., Christiansen, S. H., Ratner, C., Woldbye, David Paul Drucker & Holst, Birgitte, 26 Apr 2017, In: International Journal of Molecular Sciences. 18, 5, 17 p., 914.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Protein kinase C activity blocks neuropeptide Y-mediated inhibition of glutamate release and contributes to excitability of the hippocampus in status epilepticus

    Silva, A. P., Lourenco, J., Xapelli, S., Ferreira, R., Kristiansen, H., Woldbye, David Paul Drucker, Oliveira, C. R. & Malva, J. O., 2007, In: The FASEB Journal. 21, 3, p. 671-681 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Increased cocaine self-administration in M4 muscarinic acetylcholine receptor knockout mice.

    Schmidt, L. S., Thomsen, M., Weikop, Pia, Nielsen, D. D., Wess, J., Woldbye, David Paul Drucker, Wörtwein, Gitta & Fink-Jensen, Anders, 2011, In: Psychopharmacology. 216, 3, p. 367-378 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Increased amphetamine-induced locomotor activity, sensitization, and accumbal dopamine release in M5 muscarinic receptor knockout mice

    Schmidt, L. S., Miller, A. D., Lester, D. B., Bay-Richter, C., Schülein, C., Frikke-Schmidt, H., Wess, J., Blaha, C. D., Woldbye, David Paul Drucker, Fink-Jensen, Anders & Wörtwein, Gitta, 2010, In: Psychopharmacology. 207, 4, p. 547-58 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Modulating Dopamine Signaling and Behavior with Chemogenetics: Concepts, Progress, and Challenges

    Runegaard, A. H., Fitzpatrick, C. M., Woldbye, David Paul Drucker, Andreasen T., Jesper, Sørensen, Andreas Toft & Gether, Ulrik, 2019, In: Pharmacological Reviews. 71, 2, p. 123-156 34 p.

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published
  44. Published

    Membrane permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.

    Rickhag, Karl Mattias, Owens, W., Winkler, M., Strandfelt, K. N., Rathje, Mette, Sørensen, G., Andresen, B., Madsen, Kenneth Lindegaard, Nygaard Jørgensen, T., Wörtwein, Gitta, Woldbye, David Paul Drucker, Sitte, H. H., Daws, L. C. & Gether, Ulrik, 2013, In: Journal of Biological Chemistry. 288, p. 27534-44 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter

    Rickhag, Karl Mattias, Herborg, Freja, Sørensen, G., Strandfelt, K. N., Andresen, B., Gotfryd, K., Madsen, Kenneth Lindegaard, Vestergaard-Klewe, I., Ammendrup-Johnsen, I., Eriksen, J., Newman, A. H., Füchtbauer, E., Gomeza, J., Woldbye, David Paul Drucker, Wörtwein, Gitta & Gether, Ulrik, 2013, In: Nature Communications. 4, p. 1-13 13 p., 1580.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    In vivo characterization of high Basal signaling from the ghrelin receptor

    Petersen, P. S., Woldbye, David Paul Drucker, Madsen, A. N., Egerod, Kristoffer Lihme, Jin, C., Lang, M., Rasmussen, M., Beck-Sickinger, A. G. & Holst, Birgitte, 2009, In: Endocrinology. 150, 11, p. 4920-30 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Gene expression in the neuropeptide Y system during ethanol withdrawal kindling in rats

    Olling, J. D., Ulrichsen, J., Correll, M., Woldbye, David Paul Drucker, Olling, J. D., Ulrichsen, J., Correll, M. & Woldbye, D. P. D., 1 Mar 2010, In: Alcoholism: Clinical and Experimental Research. 34, 3, p. 462-70 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Decreased gene expression of neuropeptide Y and its receptors in hippocampal regions during ethanol withdrawal in rats

    Olling, J. D., Ulrichsen, J., Haugbøl, S., Glenthøj, Birte Yding, Hemmingsen, R. & Woldbye, David Paul Drucker, 2007, In: Neuroscience Letters. 424, 3, p. 160-164 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Complex plastic changes in the neuropeptide Y system during ethanol intoxication and withdrawal in the rat brain

    Olling, J. D., Ulrichsen, J., Christensen, D. Z., Woldbye, David Paul Drucker, Olling, J. D., Ulrichsen, J., Christensen, D. Z. & Woldbye, D. P. D., 2009, In: Journal of Neuroscience Research. 87, 10, p. 2386-97 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    The short/long polymorphism in the serotonin transporter gene promoter is not associated with panic disorder in a Scandinavian sample

    Olesen, O. F., Bennike, B. G., Steno-Hansen, E., Koefoed, P., Woldbye, David Paul Drucker, Bolwig, T. G. & Mellerup, Erling Thyge, 2005, In: Psychiatric Genetics. Vol. 15, p. 159

    Research output: Contribution to journalJournal articleResearchpeer-review

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