Claus Ernst Moser
Professor
Bacteriology
Nørre Allé 14
2200 København N
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A review of forty five open tibial fractures covered with free flaps. Analysis of complications, microbiology and prognostic factors
Olesen, U. K., Juul, R., Bonde, C. T., Moser, Claus Ernst, McNally, M., Jensen, L. T., Elberg, J. J. & Eckardt, H., Jun 2015, In: International Orthopaedics. 39, 6, p. 1159-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prevalence and Mortality of Infective Endocarditis in Community-Acquired and Healthcare-Associated Staphylococcus aureus Bacteremia: A Danish Nationwide Registry-Based Cohort Study
Ostergaard, L., Voldstedlund, M., Bruun, N. E., Bundgaard, H., Iversen, K., Kober, N., Dahl, A., Chamat-Hedemand, S., Petersen, J. K., Jensen, A. D., Christensen, J. J., Rosenvinge, F. S., Jarlov, J. O., Moser, C., Andersen, C. O., Coia, J., Marmolin, E. S., Sogaard, K. K., Lemming, L., Kober, L. & 1 others, , 2022, In: Open Forum Infectious Diseases. 9, 12, 9 p., 647.Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical implementation of partial oral treatment in infective endocarditis: the Danish POETry study
Pries-Heje, M. M., Hjulmand, J. G., Lenz, I. T., Hasselbalch, R. B., Povlsen, J. A., Ihlemann, N., Køber, N., Tofterup, M. L., Østergaard, L., Dalsgaard, M., Faurholt-Jepsen, D., Wienberg, M., Christiansen, U., Bruun, Niels Eske, Fosbøl, E., Moser, Claus Ernst, Iversen, Kasper & Bundgård, Henning, 2023, In: European Heart Journal. 44, 48, p. 5095-5106Research output: Contribution to journal › Journal article › Research › peer-review
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Dietzia papillomatosis Bacteremia
Rammer, P., Calum, Henrik Pierre, Moser, Claus Ernst, Björnsdóttir, M. K., Smedegaard, H., Høiby, Niels & Bjarnsholt, Thomas, Jun 2013, In: Journal of Clinical Microbiology. 51, 6, p. 1977-8 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Whole genome sequencing as a tool for phylogenetic analysis of clinical strains of Mitis group streptococci
Rasmussen, L. H., Dargis, R., Højholt, K., Christensen, J. J., Skovgaard, O., Justesen, U. S., Rosenvinge, F. S., Moser, Claus Ernst, Lukjancenko, O., Rasmussen, Simon & Nielsen, X. C., Oct 2016, In: European Journal of Clinical Microbiology & Infectious Diseases. 35, 10, p. 1615-1625Research output: Contribution to journal › Journal article › Research › peer-review
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In silico assessment of virulence factors in strains of streptococcus oralis and Streptococcus mitis isolated from patients with infective endocarditis
Rasmussen, L. H., Højholt, K., Dargis, R., Christensen, J. J., Skovgaard, O., Justesen, U. S., Rosenvinge, F. S., Moser, Claus Ernst, Lukjancenko, O., Rasmussen, Simon & Nielsen, X. C., 1 Sep 2017, In: Journal of Medical Microbiology. 66, p. 1316-1323 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Five-Year Outcomes of the Partial Oral Treatment of Endocarditis (POET) Trial
Rosenvinge, F., Helweg-Larsen, J., Fosbol, E. L., Køber, Lars Valeur, Torp-Pedersen, C., Tonder, N., Moser, Claus Ernst, Iversen, Kasper & Bundgård, Henning, 10 Feb 2022, In: New England Journal of Medicine. 386, 6, p. 601-602 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Comparing culture and molecular methods for the identification of microorganisms involved in necrotizing soft tissue infections
Rudkjøbing, V. B., Thomsen, T. R., Xu, Y., Melton-Kreft, R., Ahmed, A., Eickhardt-Dalbøge, S. R., Bjarnsholt, Thomas, Poulsen, Steen Seier, Nielsen, P. H., Earl, J. P., Ehrlich, G. D. & Moser, Claus Ernst, 8 Nov 2016, In: B M C Infectious Diseases. 16, 13 p., 652.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel human in vitro vegetation simulation model for infective endocarditis
Schwartz, F. A., Christophersen, L., Laulund, A. S., Lundquist, R., Lerche, C., Rude Nielsen, P., Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2021, In: APMIS. 129, 11, p. 653-662 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Distinct contribution of hyperbaric oxygen therapy to human neutrophil function and antibiotic efficacy against Staphylococcus aureus
Schwartz, F. A., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Laulund, A. S., Woetmann, Anders , Høiby, Niels & Moser, Claus Ernst, 2021, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 129, 9, p. 566-573Research output: Contribution to journal › Journal article › Research › peer-review
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Chicken IgY reduces the risk of Pseudomonas aeruginosa urinary tract infections in a murine model
Schwartz, F. A., Christophersen, L., Thomsen, K., Baekdal, S., Pals Bendixen, M., Jørgensen, M., Bull Rasmussen, I. K., Laulund, A. S., Høiby, Niels & Moser, Claus Ernst, 2022, In: Frontiers in Microbiology. 13, 988386.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamics of a Staphylococcus aureus infective endocarditis simulation model
Schwartz, F. A., Nielsen, L., Struve Andersen, J., Bock, M., Christophersen, L., Sunnerhagen, T., Lerche, C. J., Bay, Lene, Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 8, p. 515-523Research output: Contribution to journal › Journal article › Research › peer-review
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Pseudomonas aeruginosa antibody response in cystic fibrosis decreases rapidly following lung transplantation
Schwensen, H. F., Moser, Claus Ernst, Perch, Michael, Pressler, T. & Høiby, Niels, 2020, In: Journal of Cystic Fibrosis. 19, 4, p. 587-594Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma concentration of orally administered amoxicillin and clindamycin in patients receiving haemodialysis
Solli, C. N., Bock, M., Kaur, K. P., Kristensen, J. H., Greibe, E., Hansen, H. P., Boesby, L., Borg, Rikke, Chaudry, M., Hoffmann-Lücke, E., Moser, Claus Ernst, Falkentoft, A. C., Fosbøl, E., Østergaard, L., Torp-Pedersen, Christian, Bundgård, Henning, Iversen, Kasper & Bruun, Niels Eske, 2023, In: Journal of Antimicrobial Chemotherapy. 78, 3, p. 724-731 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biofilm formation on endovascular aneurysm repair (EVAR) grafts- a proof of concept in vitro model
Sunnerhagen, T., Schwartz, F., Christophersen, L., Bjarnsholt, Thomas, Qvortrup, Klaus, Eldrup, Nikolaj, Vogt, K. & Moser, Claus Ernst, 2023, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 29, 12, p. 1600.e1-1600.e6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The phagocytic fitness of leucopatches may impact the healing of chronic wounds
Thomsen, K., Trøstrup, H., Christophersen, L., Lundquist, R., Høiby, Niels & Moser, Claus Ernst, 2016, In: Clinical and Experimental Immunology. 184, 3, p. 368-77 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils
Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Jul 2015, In: Infection and Immunity. 83, 7, p. 2686-2693 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model
Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Mar 2016, In: Journal of Cystic Fibrosis. 15, 2, p. 171-178 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immune Response to Biofilm Growing Pulmonary Pseudomonas aeruginosa Infection
Thomsen, K., Høiby, Niels, Jensen, Peter Østrup, Ciofu, Oana & Moser, Claus Ernst, 2022, In: Biomedicines. 10, 9, 2064.Research output: Contribution to journal › Review › Research › peer-review
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Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils
Thomsen, K., Christophersen, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, Claus Ernst & Høiby, Niels, Jul 2016, In: Human Vaccines & Immunotherapeutics. 12, 7, p. 1690-1699 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment
Thomsen, K., Kobayashi, O., Kishi, K., Shirai, R., Jensen, Peter Østrup, Heydorn, A., Hentzer, M., Calum, Henrik Pierre, Christophersen, L., Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 7, p. 458-476Research output: Contribution to journal › Review › Research › peer-review
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Azithromycin potentiates avian IgY effect against Pseudomonas aeruginosa in a murine pulmonary infection model
Thomsen, K., Christophersen, L., Lerche, C. J., Holmgaard, D. B., Calum, Henrik Pierre, Høiby, Niels & Moser, Claus Ernst, 2021, In: International Journal of Antimicrobial Agents. 57, 1, 106213.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of bacterial biofilms in infections of catheters and shunts
Thomsen, T. R., Hall-Stoodley, L., Moser, Claus Ernst & Stoodley, P., 2010, Biofilm Infections.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Chronic urinary tract infections in patients with spinal cord lesions – biofilm infection with need for long-term antibiotic treatment
Tofte, N., Nielsen, A. C. Y., Trøstrup, H., Andersen, C. B., Von Linstow, M., Hansen, B., Biering-Sørensen, Fin, Høiby, Niels & Moser, Claus Ernst, Apr 2017, In: APMIS. 125, 4, p. 385-391 7 p.Research output: Contribution to journal › Review › Research › peer-review
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Taurolidine-citrate-heparin lock reduces catheter-related bloodstream infections in intestinal failure patients dependent on home parenteral support: a randomized, placebo-controlled trial
Tribler, S., Brandt, C. F., Petersen, Anne Helby, Petersen, Jørgen Holm, Fuglsang, K. A., Staun, Michael, Broebech, P., Moser, Claus Ernst & Jeppesen, Palle Bekker, Sep 2017, In: The American Journal of Clinical Nutrition. 106, 3, p. 839-848 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Catheter-related bloodstream infections in patients with intestinal failure receiving home parenteral support: risks related to a catheter-salvage strategy
Tribler, S., Brandt, C. F., Fuglsang, K. A., Staun, Michael, Broebech, P., Moser, Claus Ernst, Scheike, Thomas & Jeppesen, Palle Bekker, 2018, In: American Journal of Clinical Nutrition. 107, 5, p. 743-753 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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S100A8/A9 WOUND FLUID LEVELS ARE REDUCED IN NON-HEALING VENOUS LEG ULCERS COMPARED WITH NEUROPATHIC FOOT ULCERS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
Trostrup, H., Laursen, A. C., Holstein, P., Christophersen, L., Jorgensen, B., Karlsmark, Tonny, Høiby, Niels, Moser, Claus Ernst & Agren, M. S., 2015, In: Wound Repair and Regeneration. 23, 4, p. A31-A31 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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PSEUDOMONAS AERUGINOSA BIOFILM INFECTION SUPPRESSES LOCAL HOST RESPONSE IN BURN WOUNDS
Trostrup, H., Lerche, C. J., Christophersen, L., Thomsen, K., Jensen, P. O., Høiby, Niels & Moser, Claus Ernst, 2015, In: Wound Repair and Regeneration. 23, 4, p. A31-A31 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor
Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Feb 2018, In: International Wound Journal. 15, 1, p. 123-132Research output: Contribution to journal › Journal article › Research › peer-review
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Animal models of chronic wound care: the application of biofilms in clinical research
Trøstrup, H., Thomsen, K., Calum, Henrik Pierre, Høiby, Niels & Moser, Claus Ernst, 2016, In: Chronic Wound Care Management and Research. 3, p. 123-132 10 p.Research output: Contribution to journal › Review › Research › peer-review
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Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines—implications for delayed wound closure?
Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Oct 2017, In: Pathogens and Disease. 75, 7, 10 p., ftx068.Research output: Contribution to journal › Journal article › Research › peer-review
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Pseudomonas aeruginosa biofilm aggravates skin inflammatory response in BALB/c mice in a novel chronic wound model
Trøstrup, H., Thomsen, K., Christophersen, L. J., Hougen, H. P., Bjarnsholt, Thomas, Jensen, Peter Østrup, Kirkby, N., Calum, H., Høiby, Niels & Moser, Claus Ernst, Mar 2013, In: Wound Repair and Regeneration. 21, 2, p. 292-299 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Uncontrolled gelatin degradation in non-healing chronic wounds
Trøstrup, H., Holstein, P., Karlsmark, Tonny, Moser, Claus Ernst & Ågren, Magnus, 2018, In: Journal of Wound Care. 27, 11, p. 724-734 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds
Trøstrup, H., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Molecular Sciences. 18, 7, 13 p., 1359.Research output: Contribution to journal › Journal article › Research › peer-review
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S100A8/A9 is an important host defence mediator in neuropathic foot ulcers in patients with type 2 diabetes mellitus
Trøstrup, H., Holstein, P., Christophersen, L., Jørgensen, B., Karlsmark, Tonny, Høiby, Niels, Moser, Claus Ernst & Ågren, Magnus, 1 Jul 2016, In: Archives of Dermatological Research. 308, 5, p. 347-355 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biopsy-verified bronchiolitis obliterans and other noninfectious lung pathologies after allogeneic hematopoietic stem cell transplantation
Uhlving, H. H., Andersen, C. B., Christensen, I. J., Gormsen, M., Pedersen, K. D., Buchvald, F., Heilmann, C., Nielsen, K. G., Mortensen, Jann, Moser, Claus Ernst, Sengeløv, Henrik & Muller, Klaus, Mar 2015, In: Biology of Blood and Marrow Transplantation. 21, 3, p. 531-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recurrent prosthetic valve endocarditis caused by Aspergillus delacroxii (formerly Aspergillus nidulans var. echinulatus)
Uhrin, G. B., Jensen, R. H., Korup, E., Gronlund, J., Hjort, U., Moser, Claus Ernst, Arendrup, M. C. & Schonheyder, H. C., Dec 2015, In: Medical Mycology Case Reports. 10, p. 21-23Research output: Contribution to journal › Journal article › Research › peer-review
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Microbial Trends in Infection-related Readmissions Following Radical Cystectomy for Bladder Cancer
Vejlgaard, M., Maibom, S. L., Joensen, Ulla Nordström, Moser, Claus Ernst & Røder, Andreas, 2024, In: Urology. 183, 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Markers of intestinal mucositis to predict blood stream infections at the onset of fever during treatment for childhood acute leukemia
Weischendorff, S., Rathe, M., Petersen, M. J., Weimann, A., Enevold, C., Nielsen, C. H., Als-Nielsen, B., Nygaard, Ulrikka, Moser, Claus Ernst & Muller, Klaus, 2024, In: Leukemia. 38, p. 14–20 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Markers of neutrophil chemotaxis for identification of blood stream infections in children with acute lymphoblastic leukemia undergoing induction treatment
Weischendorff, S., De Pietri, S., Rathe, M., Frandsen, T. L., Hasle, H., Nielsen, Claus Henrik, Moser, Claus Ernst & Muller, Klaus, 2023, In: European Journal of Haematology. 110, 6, p. 762-771Research output: Contribution to journal › Journal article › Research › peer-review
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Detection of microbial diversity in endocarditis using cultivation-independent molecular techniques
Wolff, T. Y., Moser, Claus Ernst, Bundgaard, H., Høiby, Niels, Nielsen, P. H. & Thomsen, T. R., 26 Aug 2011, In: Scandinavian Journal of Infectious Diseases. 43, 11-12, p. 857-869Research output: Contribution to journal › Journal article › Research › peer-review
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Når bakterien skal afsløres hurtigt
Wolff, T. Y., Nielsen, P. H., Moser, Claus Ernst & Thomsen, T. R., 2010, In: Aktuel Naturvidenskab. 4, p. 28-31Research output: Contribution to journal › Journal article › Research
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Direct sequencing and RipSeq interpretation as a tool for identification of polymicrobial infections
Wolff, T. Y., Eickhardt, S., Björnsdottir, M. K., Moser, Claus Ernst, Bjarnsholt, Thomas, Høiby, Niels & Thomsen, T. R., Apr 2013, In: Journal of Clinical Microbiology. 51, 4, p. 1281-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa
Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Heydorn, A., Mathee, K., Moser, Claus Ernst, Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146 ( Pt 10), p. 2481-93 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipocalin 2 is protective against E. coli pneumonia
Wu, H., Santoni-Rugiu, E., Ralfkiaer, E., Porse, Bo Torben, Moser, Claus Ernst, Høiby, Niels, Borregaard, N. & Cowland, J. B., 2010, In: Respiratory research. 11, p. 96Research output: Contribution to journal › Journal article › Research › peer-review
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Strategies for combating bacterial biofilm infections
Wu, H., Moser, Claus Ernst, Wang, H., Høiby, Niels & Song, Z., 2015, In: International Journal of Oral Science. 7, 1, p. 1-7 7 p.Research output: Contribution to journal › Review › Research › peer-review
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Culture-dependent and -independent investigations of microbial diversity on urinary catheters
Xu, Y., Moser, Claus Ernst, Abu Al-Soud, W., Sørensen, Søren Johannes, Høiby, Niels, Nielsen, P. H. & Thomsen, T. R., 2012, In: Journal of Clinical Microbiology. 50, 12, p. 3901-3908 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Combination and nanotechnology based pharmaceutical strategies for combating respiratory bacterial biofilm infections
Zhang, L., Bera, H., Wang, H., Wang, J., Guo, Y., Shi, C., Cun, D., Moser, Claus Ernst, Høiby, Niels & Yang, Mingshi, 2022, In: International Journal of Pharmaceutics. 616, 121507.Research output: Contribution to journal › Review › Research › peer-review
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Infective endocarditis in patients who have undergone transcatheter aortic valve implantation: a review
Østergaard, L., Lauridsen, T. K., Iversen, Kasper, Bundgård, Henning, Søndergaard, Lars, Ihlemann, N., Moser, Claus Ernst & Fosbøl, E., 2020, In: Clinical Microbiology and Infection. 26, 8, p. 999-1007 9 p.Research output: Contribution to journal › Review › Research › peer-review
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Recurrence of bacteremia and infective endocarditis according to bacterial species of index endocarditis episode
Østergaard, L., Voldstedlund, M., Bruun, Niels Eske, Bundgård, Henning, Iversen, Kasper, Pries-Heje, M. M., lvs502, lvs502, Graversen, P. L., Moser, Claus Ernst, Andersen, C. Ø., Søgaard, K. K., Køber, Lars Valeur & Fosbøl, E. L., 2023, In: Infection. 51, p. 1739–1747Research output: Contribution to journal › Journal article › Research › peer-review
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Infektiøs endokarditis
Østergaard, L., Valeur, N., Tuxen, C. D., Bundgård, Henning, Iversen, Kasper, Moser, Claus Ernst, Helweg-Larsen, J., Smerup, Morten Holdgaard, Bruun, Niels Eske & Fosbøl, E., 21 Mar 2022, In: Ugeskrift for Laeger. 184, 12, 9 p., V10210751.Research output: Contribution to journal › Review › Research › peer-review
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Prevalence of infective endocarditis in patients with positive blood cultures: a Danish nationwide study
Østergaard, L., Bruun, N. E., Voldstedlund, M., Arpi, M., Andersen, C. Ø., Schønheyder, H. C., Lemming, L., Rosenvinge, F., Valeur, N., Søgaard, P., Andersen, P. S., Skov, R., Chen, M., Iversen, K., Gill, S., Lauridsen, T. K., Dahl, A., Oestergaard, L. B., Povlsen, J. A., Moser, C. & 3 others, , 2019, In: European Heart Journal. 40, 39, p. 3237-3244 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Temporal Changes, Patient Characteristics, and Mortality, According to Microbiological Cause of Infective Endocarditis: A Nationwide Study
Østergaard, L., Voldstedlund, M., Bruun, Niels Eske, Bundgård, Henning, Iversen, Kasper, Køber, N., Christensen, J. J., Rosenvinge, F. S., Jarløv, J. O., Moser, Claus Ernst, Andersen, C. Ø., Coia, J., Marmolin, E. S., Søgaard, K. K., Lemming, L., Køber, Lars Valeur & Fosbøl, E. L., 2022, In: Journal of the American Heart Association. 11, 16, e025801.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 22545315
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
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