Chuna Ram Choudhary

Chuna Ram Choudhary

professor, group leader


  1. Published

    A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex

    Starnes, L. M., Su, D., Pikkupeura, Laura Maarit, Weinert, B. T., Santos, M. A., Mund, Andreas, Soria, R., Cho, Y., Pozdnyakova, I., Kubec Højfeldt, M., Lages Lino Vala, A., Yang, W., López-Méndez, B., Lee, J., Peng, W., Yuan, J., Ge, K., Montoya, Guillermo, Nussenzweig, A., Choudhary, Chunaram & Daniel, J. A., 15 Jan 2016, In: Genes & Development. 30, 2, p. 149-163 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

    Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, Michael Lund, Cox, J., Mann, Matthias & Choudhary, Chunaram, 1 Oct 2011, In: Molecular and Cellular Proteomics. 10, 10, p. M111.013284

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

    Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chunaram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In: E M B O Journal. 32, 23, p. 3029-3040

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1

    Blasius, M., Forment, J. V., Thakkar, N., Wagner, S. A., Choudhary, Chunaram & Jackson, S. P., 2011, In: Genome Biology (Online Edition). 12, 8, p. R78

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response

    Blasius, M., Wagner, S. A., Choudhary, Chunaram, Bartek, J. & Jackson, S. P., 4 Sep 2014, In: Genes & Development. 28, 18, p. 1977-1982 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Accurate quantification of site-specific acetylation stoichiometry reveals the impact of sirtuin deacetylase CobB on the E. coli acetylome

    Weinert, B. T., Satpathy, S., Hansen, B. K., Lyon, D., Jensen, Lars Juhl & Choudhary, Chunaram, May 2017, In: Molecular and Cellular Proteomics. 16, p. 759-769

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli

    Weinert, B. T., Iesmantavicius, V., Wagner, S. A., Schölz, C., Gummesson, Bertil, Beli, P., Nyström, T. & Choudhary, Chunaram, 25 Jul 2013, In: Molecular Cell. 51, 2, p. 265-272 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae

    Weinert, B. T., Iesmantavicius, V., Moustafa, T., Schölz, C., Wagner, S. A., Magnes, C., Zechner, R. & Choudhary, Chunaram, 31 Jan 2014, In: Molecular Systems Biology. 10, 1, p. 716 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Acetylation of intrinsically disordered regions regulates phase separation

    Saito, M., Hess, D., Eglinger, J., Fritsch, A. W., Kreysing, M., Weinert, B. T., Choudhary, Chunaram & Matthias, P., Jan 2019, In: Nature Chemical Biology. 15, 1, p. 51-61

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Acetylation site specificities of lysine deacetylase inhibitors in human cells

    Schölz, C., Weinert, B. T., Wagner, S. A., Beli, P., Miyake, Y., Qi, J., Jensen, Lars Juhl, Streicher, W., McCarthy, A. R., Westwood, N. J., Lain, S., Cox, J., Matthias, P., Mann, M., Bradner, J. E. & Choudhary, Chunaram, 2015, In: Nature Biotechnology. 33, p. 415–423

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Analysis and Interpretation of Protein Post-Translational Modification Site Stoichiometry

    Prus, G., Hoegl, A., Weinert, B. T. & Choudhary, Chunaram, 2019, In: Trends in Biochemical Sciences. 44, 11, p. 943-960

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions

    Weinert, B. T., Moustafa, T., Iesmantavicius, V., Zechner, R. & Choudhary, Chunaram, 3 Nov 2015, In: E M B O Journal. 34, 21, p. 2620-2632 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation

    Hansen, B. K., Gupta, R., Baldus, L., Lyon, D., Narita, Takeo, Lammers, M., Choudhary, Chunaram & Weinert, B. T., 2019, In: Nature Communications. 10, 11 p., 1055.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Avoiding abundance bias in the functional annotation of posttranslationally modified proteins

    Schölz, C., Lyon, D., Refsgaard, J. C., Jensen, Lars Juhl, Choudhary, Chunaram & Weinert, B. T., Nov 2015, In: Nature Methods. 12, p. 1003-4 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  15. Published

    Convergence of Ubiquitylation and Phosphorylation Signaling in Rapamycin-Treated Yeast Cells

    Iesmantavicius, V., Weinert, B. T. & Choudhary, Chunaram, 24 Jun 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1979-92 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

    Gupta, R., Somyajit, K., Narita, Takeo, Maskey, E., Stanlie, A., Kremer, M., Typas, Dimitris, Lammers, M., Mailand, Niels, Nussenzweig, A., Lukas, Jiri & Choudhary, Chunaram, 2018, In: Cell. 173, 4, p. 972-988

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

    Mosbech, A., Gibbs-Seymour, I., Kagias, K., Thorslund, T., Beli, P., Povlsen, L., Nielsen, Sofie Vincents, Smedegaard, S., Sedgwick, G., Lukas, Claudia, Hartmann-Petersen, Rasmus, Lukas, Jiri, Choudhary, Chunaram, Pocock, R. D. J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Structural and Molecular Biology. 19, 11, p. 1084-92 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Decoding signalling networks by mass spectrometry-based proteomics

    Choudhary, Chunaram & Mann, Matthias, 1 Jun 2010, In: Nature Reviews. Molecular Cell Biology. 11, 6, p. 427-39 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Deletion of APC7 or APC16 Allows Proliferation of Human Cells without the Spindle Assembly Checkpoint

    Wild, T., Budzowska, M., Hellmuth, S., Eibes, S., Karemore, Gopal, Barisic, Marin, Stemmann, O. & Choudhary, Chunaram, 2018, In: Cell Reports. 25, 9, 18 p., 2317-2328.e5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Deubiquitylating enzyme USP9x regulates hippo pathway activity by controlling angiomotin protein turnover

    Nguyen, T. H., Andrejeva, D., Gupta, R., Choudhary, Chunaram, Hong, X., Eichhorn, P. J., Loya, Anand Chainsukh & Cohen, S. M., 29 Mar 2016, In: Cell Discovery. 2, 13 p., 16001.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

    Lasko, L. M., Jakob, C. G., Edalji, R. P., Qiu, W., Montgomery, D., Digiammarino, E. L., Hansen, T. M., Risi, R. M., Frey, R., Manaves, V., Shaw, B., Algire, M., Hessler, P., Lam, L. T., Uziel, T., Faivre, E., Ferguson, D., Buchanan, F. G., Martin, R. L., Torrent, M., Chiang, G. G., Karukurichi, K., Langston, J. W., Weinert, B. T., Choudhary, Chunaram, de Vries, P., Van Drie, J. H., McElligott, D., Kesicki, E., Marmorstein, R., Sun, C., Cole, P. A., Rosenberg, S. H., Michaelides, M. R., Lai, A. & Bromberg, K. D., 5 Oct 2017, In: Nature. 550, 7674, p. 128-132 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release

    Narita, Takeo, Ito, S., Higashijima, Yoshiki, Chu, W. K., Neumann, K., Walter, Jonas, Satpathy, S., Liebner, Tim, Hamilton, W. B., Maskey, E., Prus, G., Shibata, M., Iesmantavicius, V., Brickman, Joshua Mark, Anastassiadis, K., Koseki, H. & Choudhary, Chunaram, 2021, In: Molecular Cell. 81, 10, p. 2166-2182.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Equilibrium between nascent and parental MCM proteins protects replicating genomes

    Sedlackova, Hana, Rask, M., Gupta, R., Choudhary, Chunaram, Somyajit, K. & Lukas, Jiri, 2020, In: Nature. 587, p. 297-302 34 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Functions and mechanisms of non-histone protein acetylation

    Narita, Takeo, Weinert, B. T. & Choudhary, Chunaram, 2019, In: Nature Reviews. Molecular Cell Biology. 20, p. 156-174 19 p.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    HBO1 is required for the maintenance of leukaemia stem cells

    MacPherson, L., Anokye, J., Yeung, M. M., Lam, E. Y. N., Chan, Y., Weng, C., Yeh, P., Knezevic, K., Butler, M. S., Hoegl, A., Chan, K., Burr, M. L., Gearing, L. J., Willson, T., Liu, J., Choi, J., Yang, Y., Bilardi, R. A., Falk, H., Nghi Nguyen, Stupple, P. A., Peat, T. S., Zhang, M., De Silva, M., Carrasco-Pozo, C., Avery, V. M., Khoo, S., Dolezal, O., Dennis, M. L., Nuttall, S., Surjadi, R., Newman, J., Ren, B., Leaver, D. J., Sun, Y., Baell, J. B., Dovey, O., Vassiliou, G. S., Grebien, F., Dawson, S., Street, I. P., Monahan, B. J., Burns, C. J., Choudhary, Chunaram, Blewitt, M. E., Voss, A. K., Thomas, T. & Dawson, M. A., 2020, In: Nature. 577, 7789, p. 266-270

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 13781159