Brice Emanuelli
Associate Professor
Emanuelli Group
Blegdamsvej 3B, Mærsk Tårnet, 7. sal
2200 København N.
- 2000
SOCS-3 is an insulin-induced negative regulator of insulin signaling
Emanuelli, Brice, Peraldi, P., Filloux, C., Sawka-Verhelle, D., Hilton, D. & Van Obberghen, E., 26 May 2000, In: Journal of Biological Chemistry. 275, 21, p. 15985-15991 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
Insulin Induces Suppressor of Cytokine Signaling-3 Tyrosine Phosphorylation through Janus-activated Kinase
Peraldi, P., Filloux, C., Emanuelli, Brice, Hilton, D. J. & Van Obberghen, E., 6 Jul 2001, In: Journal of Biological Chemistry. 276, 27, p. 24614-24620 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Surfing the insulin signaling web
Van Obberghen, E., Baron, V., Delahaye, L., Emanuelli, Brice, Filippa, N., Giorgetti-Peraldi, S., Lebrun, P., Mothe-Satney, I., Peraldi, P., Rocchi, S., Sawka-Verhelle, D., Tartare-Deckert, S. & Giudicelli, J., 1 Dec 2001, In: European Journal of Clinical Investigation. 31, 11, p. 966-977 12 p.Research output: Contribution to journal › Review › Research › peer-review
SOCS-3 Inhibits Insulin Signaling and Is Up-regulated in Response to Tumor Necrosis Factor-α in the Adipose Tissue of Obese Mice
Emanuelli, Brice, Peraldi, P., Filloux, C., Chavey, C., Freidinger, K., Hilton, D. J., Hotamisligil, G. S. & Van Obberghen, E., 21 Dec 2001, In: Journal of Biological Chemistry. 276, 51, p. 47944-47949 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
The potential role of SOCS-3 in the interleukin-1beta-induced desensitization of insulin signaling in pancreatic beta-cells
Emanuelli, Brice, Glondu, M., Filloux, C., Peraldi, P. & Van Obberghen, E., Dec 2004, In: Diabetes. 53 Suppl 3, p. S97-S103Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Critical nodes in signalling pathways: insights into insulin action
Taniguchi, C. M., Emanuelli, Brice & Kahn, C. R., Feb 2006, In: Nature Reviews. Molecular Cell Biology. 7, 2, p. 85-96 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Overexpression of the dual-specificity phosphatase MKP-4/DUSP-9 protects against stress-induced insulin resistance
Emanuelli, Brice, Eberlé, D., Suzuki, R. & Kahn, C. R., 4 Mar 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 9, p. 3545-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SOCS-1 deficiency does not prevent diet-induced insulin resistance
Emanuelli, Brice, Macotela, Y., Boucher, J. & Ronald Kahn, C., 12 Dec 2008, In: Biochemical and Biophysical Research Communications. 377, 2, p. 447-52 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Cross talk between insulin and bone morphogenetic protein signaling systems in brown adipogenesis
Zhang, H., Schulz, T. J., Espinoza, D. O., Huang, T. L., Emanuelli, Brice, Kristiansen, Karsten & Tseng, Y., 1 Sep 2010, In: Molecular and Cellular Biology. 30, 17, p. 4224-33 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism
Macotela, Y., Emanuelli, Brice, Bång, A. M., Espinoza, D. O., Boucher, J., Beebe, K., Gall, W. & Kahn, C. R., 2011, In: PLOS ONE. 6, 6, p. e21187Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans
Bezy, O., Tran, T. T., Pihlajamäki, J., Suzuki, R., Emanuelli, Brice, Winnay, J., Mori, M. A., Haas, J., Biddinger, S. B., Leitges, M., Goldfine, A. B., Patti, M. E., King, G. L. & Kahn, C. R., Jun 2011, In: The Journal of Clinical Investigation. 121, 6, p. 2504-17 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
Jing, E., Emanuelli, Brice, Hirschey, M. D., Boucher, J., Lee, K. Y., Lombard, D., Verdin, E. M. & Kahn, C. R., 30 Aug 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 35, p. 14608-13 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Insulin resistance in the metabolic syndrome
Biddinger, S. B. & Emanuelli, Brice, 1 Dec 2011, Metabolic Basis of Obesity. Springer New York LLC, p. 175-198 24 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- 2012
- Published
Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5)
Palsgaard, J., Emanuelli, Brice, Winnay, J. N., Sumara, G., Karsenty, G. & Kahn, C. R., 6 Apr 2012, In: The Journal of Biological Chemistry. 287, 15, p. 12016-26 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intrinsic differences in adipocyte precursor cells from different white fat depots
Macotela, Y., Emanuelli, Brice, Mori, M. A., Gesta, S., Schulz, T. J., Tseng, Y. & Kahn, C. R., Jul 2012, In: Diabetes. 61, 7, p. 1691-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance
Vernochet, C., Mourier, A., Bezy, O., Macotela, Y., Boucher, J., Rardin, M. J., An, D., Lee, K. Y., Ilkayeva, O. R., Zingaretti, C. M., Emanuelli, Brice, Smyth, G., Cinti, S., Newgard, C. B., Gibson, B. W., Larsson, N. & Kahn, C. R., 5 Dec 2012, In: Cell Metabolism. 16, 6, p. 765-76 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Interplay between FGF21 and insulin action in the liver regulates metabolism
Emanuelli, Brice, Vienberg, S. G., Smyth, G., Cheng, C., Stanford, K. I., Arumugam, Mani, Michael, M. D., Adams, A. C., Kharitonenkov, A. & Kahn, C. R., 3 Feb 2014, In: The Journal of Clinical Investigation. 124, 2, p. 515-27 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Interplay between FGF21 and insulin action in the liver regulates metabolism
Emanuelli, Brice, Vienberg, S. G., Smyth, G., Cheng, C., Stanford, K. I., Arumugam, Mani, Michael, M. D., Adams, A. C., Kharitonenkov, A. & Kahn, C. R., Jan 2015, In: The Journal of Clinical Investigation. 125, 1, p. 458Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2016
Cross-talk between insulin and Wnt signaling in preadipocytes. ROLE OF Wnt CO-RECEPTOR LDL RECEPTOR-RELATED PROTEIN-5 (LRP5)
Palsgaard, J., Emanuelli, Brice, Winnay, J. N., Sumara, G., Karsenty, G. & Kahn, C. R., 5 Aug 2016, In: The Journal of Biological Chemistry. 291, 32, p. 16878Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2017
- Published
Bidirectional manipulation of gene expression in adipocytes using CRISPRa and siRNA
Lundh, M., Plucinska, Kaja, Isidor, Marie Sophie, Petersen, P. S. S. & Emanuelli, Brice, Oct 2017, In: Molecular Metabolism. 6, 10, p. 1313-1320 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
Sustarsic, E. G., Ma, T., Lynes, M. D., Larsen, M., Karavaeva, I., Havelund, J. F., Nielsen, C. H., Jedrychowski, M. P., Moreno-Torres, M., Lundh, M., Plucinska, K., Jespersen, N. Z., Grevengoed, T. J., Kramar, B., Peics, J., Hansen, J. B., Shamsi, F., Forss, I., Neess, D., Keipert, S. & 24 others, , 2018, In: Cell Metabolism. 28, 1, p. 159-174.e11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct signalling properties of insulin receptor substrate (IRS)-1 and IRS-2 in mediating insulin/IGF-1 action
Rabiee, A., Krüger, M., Ardenkjær-Larsen, J., Ronald Kahn, C. & Emanuelli, Brice, 2018, In: Cellular Signalling. 47, p. 1-15Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue
Lundh, M., Petersen, P. S., Isidor, Marie Sophie, Kazoka-Sørensen, D. N., Plucinska, Kaja, Shamsi, F., Ørskov, Cathrine, Tozzi, M., Brown, E. L., Andersen, E., Ma, Tao, Müller, U. A., Barrès, Romain, Kristiansen, V. B., Gerhart-Hines, Zach, Tseng, Y. & Emanuelli, Brice, 2019, In: EMBO Reports. 20, 8, e48216.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of two microRNA nodes as potential cooperative modulators of liver metabolism
Hochreuter, Mette Yde, Altıntaş, Ali, Garde, C., Emanuelli, Brice, Kahn, C. R., Zierath, Juleen R, Vienberg, S. & Barrès, Romain, 2019, In: Hepatology Research. 49, 12, p. 1451-1465Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The brominated flame retardant PBDE 99 promotes adipogenesis via regulating mitotic clonal expansion and PPARγ expression
Wen, Q., Xie, X., Zhao, C., Ren, Q., Zhang, X., Wei, D., Emanuelli, Brice & Du, Y., 2019, In: The Science of the Total Environment. 670, p. 67-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 41852944
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Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
264
downloads
Bidirectional manipulation of gene expression in adipocytes using CRISPRa and siRNA
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
119
downloads
Calsyntenin 3β Is Dynamically Regulated by Temperature in Murine Brown Adipose and Marks Human Multilocular Fat
Research output: Contribution to journal › Journal article › Research › peer-review
Published