Brenna Osborne

Brenna Osborne

Assistant Professor, Guest Researcher


  1. 2019
  2. Erratum: Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging (Cell (2018) 173(1) (74–89.e20), (S0092867418301521) (10.1016/j.cell.2018.02.008))

    Das, A., Huang, G. X., Bonkowski, M. S., Longchamp, A., Li, C., Schultz, M. B., Kim, L. J., Osborne, B., Joshi, S., Lu, Y., Treviño-Villarreal, J. H., Kang, M. J., Hung, T. T., Lee, B., Williams, E. O., Igarashi, M., Mitchell, J. R., Wu, L. E., Turner, N., Arany, Z. & 2 others, Guarente, L. & Sinclair, D. A., 7 Feb 2019, In: Cell. 176, 4, p. 944-945 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  3. Published

    Human exonuclease 1 (EXO1) regulatory functions in DNA replication with putative roles in cancer

    Keijzers, G., Bakula, Daniela Janina, Petr, Michael Angelo, Madsen, N. G. K., Teklu, Amanuel Abraha, Mkrtchyan, Garik, Osborne, Brenna & Scheibye-Knudsen, Morten, 2019, In: International Journal of Molecular Sciences . 20, 1, 15 p., 74.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Snail-Overexpression Induces Epithelial-mesenchymal Transition and Metabolic Reprogramming in Human Pancreatic Ductal Adenocarcinoma and Non-tumorigenic Ductal Cells

    Liu, M., Hancock, S. E., Sultani, G., Wilkins, B. P., Ding, E., Osborne, Brenna, Quek, L. & Turner, N., 8 Jun 2019, In: Journal of Clinical Medicine. 8, 6, 822.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Regulation of mitochondrial metabolism in murine skeletal muscle by the medium-chain fatty acid receptor Gpr84

    Montgomery, M. K., Osborne, Brenna, Brandon, A. E., O'Reilly, L., Fiveash, C. E., Brown, S. H. J., Wilkins, B. P., Samsudeen, A., Yu, J., Devanapalli, B., Hertzog, A., Tolun, A. A., Kavanagh, T., Cooper, A. A., Mitchell, T. W., Biden, T. J., Smith, N. J., Cooney, G. J. & Turner, N., 2019, In: FASEB Journal. 33, 11, p. 12264-12276

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Impact of lifestyle and clinical interventions on mitochondrial function in obesity and type 2 diabetes

    Osborne, Brenna, Brandon, A. E., Smith, G. C. & Turner, N., 2019, Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases. Academic Press, p. 367-397 31 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  7. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

    Somers, K., Wen, V. W., Middlemiss, S. M. C., Osborne, B., Forgham, H., Jung, M., Karsa, M., Clifton, M., Bongers, A., Gao, J., Mayoh, C., Raoufi-Rad, N., Kusnadi, E. P., Hannan, K. M., Scott, D. A., Kwek, A., Liu, B., Flemming, C., Chudakova, D. A., Pandher, R. & 17 others, Failes, T. W., Lim, J., Angeli, A., Osterman, A. L., Imamura, T., Kees, U. R., Supuran, C. T., Pearson, R. B., Hannan, R. D., Davis, T. P., McCarroll, J., Kavallaris, M., Turner, N., Gudkov, A. V., Haber, M., Norris, M. D. & Henderson, M. J., 22 May 2019, In: Oncogene. 38, p. 3824–3842

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 188144250