Brenna Osborne

Brenna Osborne

Assistant Professor

Member of:

    ORCID: 0000-0002-0197-3010

    Publication year:
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    1 - 10 out of 30Page size: 10
    1. 2023
    2. Published

      SIRT3 overexpression in rat muscle does not ameliorate peripheral insulin resistance

      Osborne, Brenna, Wright, L. E., Brandon, A. E., Stuart, E., Small, Lewin Barkla, Hoeks, J., Schrauwen, P., Sinclair, D. A., Montgomery, M. K., Cooney, G. J. & Turner, N., 2023, In: Journal of Endocrinology. 258, 3, 11 p., e220101.

      Research output: Contribution to journal › Journal article › peer-review

    3. 2022

    4. Liver-specific overexpression of SIRT3 enhances oxidative metabolism, but does not impact metabolic defects induced by high fat feeding in mice

      Osborne, Brenna, Reznick, J., Wright, L. E., Sinclair, D. A., Cooney, G. J. & Turner, N., 2022, In: Biochemical and Biophysical Research Communications. 607, p. 131-137 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    5. Published

      Nuclear morphology is a deep learning biomarker of cellular senescence

      Heckenbach, Indra John, Mkrtchyan, Garik, Ben Ezra, Michael, Bakula, Daniela Janina, Madsen, Jakob Sture, Nielsen, M. H., Oró, D., Osborne, Brenna, Covarrubias, A. J., Idda, M. L., Gorospe, M., Mortensen, Laust Hvas, Verdin, E., Westendorp, Rudi GJ & Scheibye-Knudsen, Morten, 2022, In: Nature Aging. 2, 8, p. 742-755 14 p.

      Research output: Contribution to journal › Journal article › peer-review

    6. 2020

    7. A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2

      Xi, C. R., Fazio, A. D., Nadvi, N. A., Patel, K., Xiang, M. S. W., Zhang, H. E., Deshpande, C., Low, J., Wang, X. T., Chen, Y., McMillan, C., Isaacs, A., Osborne, Brenna, Ribeiro, A. J. V. D., McCaughan, G. W., Mackay, J., Church, W. B. & Gorrell, M., Nov 2020, In: Molecules. 5392.

      Research output: Contribution to journal › Journal article › peer-review

    8. Published

      ARDD 2020: from aging mechanisms to interventions

      Mkrtchyan, Garik, Abdelmohsen, K., Andreux, P., Bagdonaite, Ieva , Barzilai, N., Brunak, Søren, Cabreiro, F., Cabo, R. D., Campisi, J., Cuervo, A. M., Demaria, M., Ewald, C. Y., Fang, E. F., Faragher, R., Ferrucci, L., Freund, A., Silva-García, C. G., Georgievskaya, A., Gladyshev, V. N., Glass, D. J., Gorbunova, V., Grey, A. D., He, W. W., Hoeijmakers, J., Hoffmann, Eva, Horvath, S., Houtkooper, R. H., Jensen, Majken Karoline, Jensen, M. B., Kane, A., Kassem, Moustapha Saad El-Deen, Keizer, P. D., Kennedy, B., Karsenty, G., Lamming, D. W., Lee, K. F., MacAulay, Nanna, Mamoshina, P., Mellon, J., Molenaars, M., Moskalev, A., Mund, Andreas, Niedernhofer, L., Osborne, Brenna, Pak, H. H., Parkhitko, A., Raimundo, N., Rando, T. A., Rasmussen, Lene Juel, Reis, C., Riedel, C. G., Franco-Romero, A., Schumacher, B., Sinclair, D. A., Suh, Y., Taub, P. R., Toiber, D., Treebak, Jonas Thue, Valenzano, D. R., Verdin, E., Vijg, J., Young, S., Zhang, L., Bakula, Daniela Janina, Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2020, In: Aging. 12, 24, p. 24486-24503 18 p.

      Research output: Contribution to journal › Journal article › peer-review

    9. Published

      New methodologies in ageing research

      Osborne, Brenna, Bakula, Daniela Janina, Ben Ezra, Michael, Dresen, C., Hartmann, E., Kristensen, S. M., Mkrtchyan, Garik, Nielsen, M. H., Petr, Michael Angelo & Scheibye-Knudsen, Morten, 2020, In: Ageing Research Reviews. 62, 11 p., 101094.

      Research output: Contribution to journal › Review › peer-review

    10. Published

      Next Generation Diabetes Scientists Shape Global Research Culture: A reflective proposal from postdoctoral researchers in diabetes research

      Gonzalez-Franquesa, A., Carrasquilla, Germán D., Mamidi, A., Ghiasi, Seyed Mojtaba, Juel, H. B., Falk, S., Isidor, Marie Sophie, Gillberg, Linn, Huang, L. O., Quist, Jonas Salling, Knudsen, Jonas Roland, Quaranta, Roberto, Tozzi, M., Mikkelsen, R. B., Dall, M., Drag, Markus Hodal, Small, Lewin Barkla, Altıntaş, Ali, Osborne, Brenna, Modvig, Ida Marie, Husted, Anna Sofie, Brown, E. L., Bak, Emilie Glad, Bastos Peluso, A. A., Finger, Fabian Michael, Grunddal, Kaare Villum, Rupar, K., Henningsen, J. B., Pedersen, M. H., Plucinska, Kaja & Attendees of the Danish Diabetes Academy Winter School 2019, A. O. T. D. D. A. W. S. 2., 2020, In: Acta Physiologica. 229, 2, 5 p., e13455.

      Research output: Contribution to journal › Comment/debate

    11. ORP5 localizes to ER–lipid droplet contacts and regulates the level of PI(4)P on lipid droplets

      Du, X., Zhou, L., Aw, Y. C., Mak, H. Y., Xu, Y., Rae, J., Wang, W., Zadoorian, A., Hancock, S. E., Osborne, Brenna, Chen, X., Wu, J., Turner, N., Parton, R. G., Li, P. & Yang, H., 2020, In: Journal of Cell Biology. e201905162.

      Research output: Contribution to journal › Journal article › peer-review

    12. 2019

    13. Snail-Overexpression Induces Epithelial-mesenchymal Transition and Metabolic Reprogramming in Human Pancreatic Ductal Adenocarcinoma and Non-tumorigenic Ductal Cells

      Liu, M., Hancock, S. E., Sultani, G., Wilkins, B. P., Ding, E., Osborne, Brenna, Quek, L. & Turner, N., 8 Jun 2019, In: Journal of Clinical Medicine. 8, 6, 822.

      Research output: Contribution to journal › Journal article › peer-review

    14. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

      Somers, K., Wen, V. W., Middlemiss, S. M. C., Osborne, Brenna, Forgham, H., Jung, M., Karsa, M., Clifton, M., Bongers, A., Gao, J., Mayoh, C., Raoufi-Rad, N., Kusnadi, E. P., Hannan, K. M., Scott, D. A., Kwek, A., Liu, B., Flemming, C., Chudakova, D. A., Pandher, R., Failes, T. W., Lim, J., Angeli, A., Osterman, A. L., Imamura, T., Kees, U. R., Supuran, C. T., Pearson, R. B., Hannan, R. D., Davis, T. P., McCarroll, J., Kavallaris, M., Turner, N., Gudkov, A. V., Haber, M., Norris, M. D. & Henderson, M. J., 22 May 2019, In: Oncogene. 38, p. 3824–3842

      Research output: Contribution to journal › Journal article › peer-review

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    ID: 188144250