Børge Nordestgaard
Clinical Professor
Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
Member of:
Clinical Biochemistry
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Exome-wide association study of plasma lipids in >300,000 individuals
Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Angelantonio, E. DI., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 208 others, , 1 Dec 2017, In: Nature Genetics. 49, 12, p. 1758-1766 9 p.Research output: Contribution to journal › Letter › Research › peer-review
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High alcohol consumption causes high IgE levels but not high risk of allergic disease
Lomholt, F. K., Nielsen, S. F. & Nordestgaard, Børge, Nov 2016, In: The Journal of allergy and clinical immunology. 138, 5, p. 1404-1413.e13Research output: Contribution to journal › Journal article › Research › peer-review
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Height, selected genetic markers and prostate cancer risk: Results from the PRACTICAL consortium
Lophatananon, A., Stewart-Brown, S., Kote-Jarai, Z., Olama, A. A. A., Garcia, S. B., Neal, D. E., Hamdy, F. C., Donovan, J. L., Giles, G. G., Fitzgerald, L. M., Southey, M. C., Pharoah, P., Pashayan, N., Gronberg, H., Aly, M., Stanford, J. L., Brenner, H., Dieffenbach, A. K., Arndt, V., Park, J. Y. & 81 others, , 2017, In: British Journal of Cancer. 117, 5, p. 734-743 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults
Lu, L., Bennett, D. A., Millwood, I. Y., Parish, S., McCarthy, M. I., Mahajan, A., Lin, X., Bragg, F., Guo, Y., Holmes, M. V., Afzal, Shoaib, Nordestgaard, Børge, Bian, Z., Hill, M., Walters, R. G., Li, L., Chen, Z. & Clarke, R., 2018, In: PLoS Medicine. 15, 5, 17 p., e1002566.Research output: Contribution to journal › Journal article › Research › peer-review
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Vitamin D and Inflammatory Bowel Disease: Mendelian Randomization Analyses in the Copenhagen Studies and UK Biobank
Lund-Nielsen, J., Vedel-Krogh, S., Kobylecki, C. J., Brynskov, J., Afzal, Shoaib & Nordestgaard, Børge, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 9, p. 3267-3277Research output: Contribution to journal › Journal article › Research › peer-review
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Neutrophil counts and cardiovascular disease
Luo, J., Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 47, p. 4953-4964 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reply to “Mendelian randomization highlights causal association between genetically increased C-reactive protein levels and reduced Alzheimer's disease risk”
Luo, J., Thomassen, J. Q., Hegazy, S. H., Rasmussen, I. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Alzheimer's & Dementia. 18, 10, p. 2007-2009 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Blood Leukocyte Counts in Alzheimer Disease
Luo, J., Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: JAMA network open. 5, 10, 14 p., E2235648.Research output: Contribution to journal › Journal article › Research › peer-review
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New Danish reference values for spirometry
Løkke, A., Marott, J. L., Mortensen, Jann, Nordestgaard, Børge, Dahl, M. & Lange, Peter, 2013, In: Clinical Respiratory Journal. 7, 2, p. 153-167Research output: Contribution to journal › Journal article › Research › peer-review
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Adverse effects of statin therapy: perception vs. the evidence - focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract
European Atherosclerosis Society Consensus Panel, E. A. S. C. P., 2018, In: European Heart Journal. 39, 27, p. 2526-2539 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Short Telomere Length and Ischemic Heart Disease: Observational and Genetic Studies in 290 022 Individuals
Madrid, A. S., Rode, L., Nordestgaard, Børge & Bojesen, Stig Egil, Aug 2016, In: Clinical Chemistry. 62, 8, p. 1140-1149 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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U-shaped relationship of HDL and risk of infectious disease: two prospective population-based cohort studies
Madsen, C. M., Varbo, A., Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth & Nordestgaard, Børge, 2018, In: European Heart Journal. 39, 14, p. 1181-1190 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Is It Time for New Thinking About High-Density Lipoprotein?
Madsen, C. M. & Nordestgaard, Børge, 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 3, p. 484-486 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Unmet need for primary prevention in individuals with hypertriglyceridaemia not eligible for statin therapy according to European Society of Cardiology/European Atherosclerosis Society guidelines: a contemporary population-based study
Madsen, C. M., Varbo, A. & Nordestgaard, Børge, 2018, In: European Heart Journal. 39, 7, p. 610-619 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipoprotein(a)-Lowering by 50 mg/dL (105 nmol/L) May Be Needed to Reduce Cardiovascular Disease 20% in Secondary Prevention: A Population-Based Study
Madsen, C. M., Kamstrup, P. R., Langsted, A., Varbo, A. & Nordestgaard, Børge, Jan 2020, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 40, 1, p. 255-266 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extreme high high-density lipoprotein cholesterol is paradoxically associated with high mortality inmen and women: Two prospective cohort studies
Madsen, C. M., Varbo, A. & Nordestgaard, Børge, 2017, In: European Heart Journal. 38, 32, p. 2478-2486Research output: Contribution to journal › Journal article › Research › peer-review
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Novel Insights from Human Studies on the Role of High-Density Lipoprotein in Mortality and Noncardiovascular Disease
Madsen, C. M., Varbo, A. & Nordestgaard, Børge, 2021, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 41, 1, p. 128-140 13 p.Research output: Contribution to journal › Review › Research › peer-review
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Low HDL Cholesterol and high risk of autoimmune disease: Two population-based cohort studies including 117341 individuals
Madsen, C. M., Varbo, A. & Nordestgaard, Børge, 2019, In: Clinical Chemistry. 65, 5, p. 644-652 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P. & 32 others, , Apr 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Large-scale transcriptome-wide association study identifies new prostate cancer risk regions
Mancuso, N., Gayther, S., Gusev, A., Zheng, W., Penney, K. L., Kote-Jarai, Z., Eeles, R., Freedman, M., Haiman, C., Pasaniuc, B., Henderson, B. E., Benlloch, S., Schumacher, F. R., Olama, A. A. A., Muir, K., Berndt, S. I., Conti, D. V., Wiklund, F., Chanock, S., Stevens, V. L. & 31 others, , 2018, In: Nature Communications. 9, 1, 11 p., 4079.Research output: Contribution to journal › Journal article › Research › peer-review
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Medication Adherence And Predictors Of Medication Adherence In Asthma
Marott, J. L., Ingebrigtsen, T. S., Lange, Peter, Nordestgaard, Børge, Dahl, Morten & Vestbo, J., May 2011, C51. ASTHMA EPIDEMIOLOGY.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
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Exacerbation history, severity of dyspnoea and maintenance treatment predicts risk of future exacerbations in patients with COPD in the general population
Marott, J. L., Çolak, Y., Ingebrigtsen, T. S., Vestbo, J., Nordestgaard, Børge & Lange, Peter, 2022, In: Respiratory Medicine. 192, 6 p., 106725.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of the metabolic syndrome on cardiopulmonary morbidity and mortality in individuals with lung function impairment: a prospective cohort study of the Danish general population
Marott, J. L., Ingebrigtsen, T. S., Çolak, Y., Kankaanranta, H., Bakke, P. S., Vestbo, J., Nordestgaard, Børge & Lange, Peter, 2023, In: The Lancet Regional Health - Europe. 35, 13 p., 100759.Research output: Contribution to journal › Journal article › Research › peer-review
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Height Explains Sex Difference in Atrial Fibrillation Risk: Copenhagen General Population Study
Marott, J. L., Jensen, M. T., Benn, Marianne, Knegt, M. C. D., O'Keefe, J. H., Lavie, C. J., Schnohr, P., Nordestgaard, Børge & Jensen, G. B., 2023, In: Mayo Clinic Proceedings. 98, 6, p. 846-855 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Predicting exacerbations in COPD in the Danish general population
Marott, J. L., Ingebrigtsen, T. S., Çolak, Y., Vestbo, J., Nordestgaard, Børge & Lange, Peter, 2024, In: Respiratory Medicine. 224, 6 p., 107557.Research output: Contribution to journal › Journal article › Research › peer-review
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AT1 mutations and risk of atrial fibrillation based on genotypes from 71,000 individuals from the general population
Marott, S. C. W., Nordestgaard, Børge, Jensen, G. B., Tybjærg-Hansen, Anne & Benn, M., 2013, In: British Journal of Clinical Pharmacology. p. Epub ahead of printResearch output: Contribution to journal › Journal article › Research › peer-review
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Does elevated C-reactive protein increase atrial fibrillation risk? A Mendelian randomization of 47,000 individuals from the general population
Marott, S. C. W., Nordestgaard, Børge, Zacho, J., Friberg, Jens Birkedal, Jensen, G. B., Tybjærg-Hansen, Anne, Benn, Marianne & Benn, M., 31 Aug 2010, In: Journal of the American College of Cardiology. 56, 10, p. 789-95 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Causal Associations in Type 2 Diabetes Development
Marott, S. C. W., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, 2019, In: The Journal of clinical endocrinology and metabolism. 104, 4, p. 1313-1324Research output: Contribution to journal › Journal article › Research › peer-review
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Antihypertensive treatment and risk of atrial fibrillation: a nationwide study
Marott, S. C. W., Nielsen, S. F., Benn, Marianne & Nordestgaard, Børge, 2014, In: European Heart Journal. 35, 18, p. 1205-2014 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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YKL-40 levels and atrial fibrillation in the general population
Marott, S. C. W., Benn, M., Johansen, J. S., Jensen, G. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2013, In: International Journal of Cardiology.Research output: Contribution to journal › Journal article › Research › peer-review
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Components of the Metabolic Syndrome and Risk of Type 2 Diabetes
Marott, S. C. W., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, Aug 2016, In: The Journal of clinical endocrinology and metabolism. 101, 8, p. 3212-3221 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rare and low-frequency coding variants alter human adult height
Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T. & 31 others, , 9 Feb 2017, In: Nature. 542, 7640, p. 186-190 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Germline variation at 8q24 and prostate cancer risk in men of European ancestry
Matejcic, M., Saunders, E. J., Dadaev, T., Brook, M. N., Wang, K., Sheng, X., Olama, A. A. A., Schumacher, F. R., Ingles, S. A., Govindasami, K., Benlloch, S., Berndt, S. I., Albanes, D., Koutros, S., Muir, K., Stevens, V. L., Gapstur, S. M., Tangen, C. M., Batra, J., Clements, J. & 31 others, , 2018, In: Nature Communications. 9, 4616.Research output: Contribution to journal › Journal article › Research › peer-review
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Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
Mavaddat, N., Michailidou, K., Dennis, J., Lush, M., Fachal, L., Lee, A., Tyrer, J. P., Chen, T-H., Wang, Q., Bolla, M. K., Yang, X., Adank, M. A., Ahearn, T., Aittomäki, K., Allen, J., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Aronson, K. J. & 31 others, , 2019, In: American Journal of Human Genetics. 104, 1, p. 21-34 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prediction of breast cancer risk based on profiling with common genetic variants
Mavaddat, N., Pharoah, P. D. P., Michailidou, K., Tyrer, J., Brook, M. N., Bolla, M. K., Wang, Q., Dennis, J., Dunning, A. M., Shah, M., Luben, R., Brown, J., Bojesen, S. E., Nordestgaard, B. G., Nielsen, S. F., Flyger, H., Czene, K., Darabi, H., Eriksson, M., Peto, J. & 192 others, , May 2015, In: National Cancer Institute. Journal (Print). 107, 5, p. 1-15 15 p., djv036.Research output: Contribution to journal › Journal article › Research › peer-review
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Serum Biomarker Signature-Based Liquid Biopsy for Diagnosis of Early-Stage Pancreatic Cancer
Mellby, L. D., Nyberg, A. P., Johansen, Julia Sidenius, Wingren, C., Nordestgaard, Børge, Bojesen, Stig Egil, Mitchell, B. L., Sheppard, B. C., Sears, R. C. & Borrebaeck, C. A. K., 2018, In: Journal of Clinical Oncology. 36, 28, p. 2887-2894 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fine-Scale Mapping of the FGFR2 Breast Cancer Risk Locus: Putative Functional Variants Differentially Bind FOXA1 and E2F1
Meyer, K. B., O'Reilly, M., Michailidou, K., Carlebur, S., Edwards, S. L., French, J. D., Prathalingham, R., Dennis, J., Bolla, M. K., Wang, Q., de Santiago, I., Hopper, J. L., Tsimiklis, H., Apicella, C., Southey, M. C., Schmidt, M. K., Broeks, A., Van 't Veer, L. J., Hogervorst, F. B., Muir, K. & 181 others, , 2013, In: American Journal of Human Genetics. 93, 6, p. 1046–1060 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased rheumatoid factor and deep venous thrombosis: 2 cohort studies of 54628 individuals from the general population
Meyer-Olesen, C. L., Nielsen, S. F. & Nordestgaard, Børge, Feb 2015, In: Clinical Chemistry. 61, 2, p. 349-59 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
Michailidou, K., Beesley, J., Lindstrom, S., Canisius, S., Dennis, J., Lush, M. J., Maranian, M. J., Bolla, M. K., Wang, Q., Shah, M., Perkins, B. J., Czene, K., Eriksson, M., Darabi, H., Brand, J. S., Bojesen, S. E., Nordestgaard, B. G., Flyger, H., Nielsen, S. F., Rahman, N. & 31 others, , Apr 2015, In: Nature Genetics. 47, 4, p. 373-80 + 1 unpag. 9 p.Research output: Contribution to journal › Letter › Research › peer-review
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Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Michailidou, K., Hall, P., Gonzalez-Neira, A., Ghoussaini, M., Dennis, J., Milne, R. L., Schmidt, M. K., Chang-Claude, J., Bojesen, S. E., Bolla, M. K., Wang, Q., Dicks, E., Lee, A. R., Turnbull, C., Rahman, N., Fletcher, O., Peto, J., Gibson, L., Dos Santos Silva, I., Nevanlinna, H. & 31 others, , Apr 2013, In: Nature Genetics. 45, 4, p. 353-61, 361e1-2Research output: Contribution to journal › Journal article › Research › peer-review
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Association analysis identifies 65 new breast cancer risk loci
Michailidou, K., Lindström, S., Dennis, J., Beesley, J., Hui, S., Kar, S., Lemaçon, A., Soucy, P., Glubb, D., Rostamianfar, A., Bolla, M. K., Wang, Q., Tyrer, J., Dicks, E., Lee, A., Wang, Z., Allen, J., Keeman, R., Eilber, U., French, J. D. & 34 others, , Nov 2017, In: Nature. 551, 7678, p. 92-94 3 p.Research output: Contribution to journal › Letter › Research › peer-review
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A genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry
Middha, P., Wang, X., Behrens, S., Bolla, M. K., Wang, Q., Dennis, J., Michailidou, K., Ahearn, T. U., Andrulis, I. L., Anton-Culver, H., Arndt, V., Aronson, K. J., Auer, P. L., Augustinsson, A., Baert, T., Freeman, L. E. B., Becher, H., Beckmann, M. W., Benitez, J., Bojesen, S. E. & 33 others, , 2023, In: Breast cancer research : BCR. 25, 1, 13 p., 93.Research output: Contribution to journal › Journal article › Research › peer-review
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Diagnostic value of postprandial triglyceride testing in healthy subjects: a meta-analysis
Mihas, C., Kolovou, G. D., Mikhailidis, D. P., Kovar, J., Lairon, D., Nordestgaard, Børge, Ooi, T. C., Perez-Martinez, P., Bilianou, H., Anagnostopoulou, K. & Panotopoulos, G., 2011, In: Current Vascular Pharmacology. 9, 3, p. 271-80 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Causal risk factors for asthma in Mendelian randomization studies: A systematic review and meta-analysis
Mikkelsen, H., Landt, E. M., Benn, Marianne, Nordestgaard, Børge & Dahl, Morten, 2022, In: Clinical and Translational Allergy. 12, 11, e12207.Research output: Contribution to journal › Review › Research › peer-review
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Increased ferritin concentration and risk of atrial fibrillation and heart failure in men and women: Three studies of the Danish general population including 35799 individuals
Mikkelsen, L. F., Nordestgaard, Børge, Schnohr, P. & Ellervik, Christina, 2019, In: Clinical Chemistry. 65, 1, p. 180-188 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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7q21-rs6964587 and breast cancer risk: an extended case-control study by the Breast Cancer Association Consortium
Milne, R. L., Lorenzo-Bermejo, J., Burwinkel, B., Malats, N., Arias, J. I., Zamora, M. P., Benítez, J., Humphreys, M. K., García-Closas, M., Chanock, S. J., Lissowska, J., Sherman, M. E., Mannermaa, A., Kataja, V., Kosma, V-M., Nevanlinna, H., Heikkinen, T., Aittomäki, K., Blomqvist, C., Anton-Culver, H. & 31 others, , 2011, In: Journal of Medical Genetics. 48, 10, p. 698-702 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium
Milne, R. L., Burwinkel, B., Michailidou, K., Arias-Perez, J-I., Zamora, M. P., Menéndez-Rodríguez, P., Hardisson, D., Mendiola, M., González-Neira, A., Pita, G., Alonso, M. R., Dennis, J., Wang, Q., Bolla, M. K., Swerdlow, A., Ashworth, A., Orr, N., Schoemaker, M., Ko, Y-D., Brauch, H. & 31 others, , 2014, In: Human Molecular Genetics. 23, 22, p. 6096-6111 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Confirmation of 5p12 As a Susceptibility Locus for Progesterone-Receptor-Positive, Lower Grade Breast Cancer
Milne, R. L., Goode, E. L., García-Closas, M., Couch, F. J., Severi, G., Hein, R., Fredericksen, Z., Malats, N., Zamora, M. P., Pérez, J. I. A., Benítez, J., Dörk, T., Schürmann, P., Karstens, J. H., Hillemanns, P., Cox, A., Brock, I. W., Elliot, G., Cross, S. S., Seal, S. & 31 others, , 1 Oct 2011, In: Cancer Epidemiology, Biomarkers & Prevention. 20, 10, p. 2222-2231 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
Milne, R. L., Herranz, J., Michailidou, K., Dennis, J., Tyrer, J. P., Zamora, M. P., Arias-Perez, J. I., González-Neira, A., Pita, G., Alonso, M. R., Wang, Q., Bolla, M. K., Czene, K., Eriksson, M., Humphreys, K., Darabi, H., Li, J., Anton-Culver, H., Neuhausen, S. L., Ziogas, A. & 31 others, , 1 Apr 2014, In: Human Molecular Genetics. 23, 7, p. 1934-1946 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
Milne, R. L., Kuchenbaecker, K. B., Michailidou, K., Beesley, J., Kar, S., Lindström, S., Hui, S., Lemaçon, A., Soucy, P., Dennis, J., Jiang, X., Rostamianfar, A., Finucane, H., Bolla, M. K., McGuffog, L., Wang, Q., Aalfs, C. M., ABCTB Investigators, Adams, M., Adlard, J. & 27 others, , 2017, In: Nature Genetics. 49, 12, p. 1767-1778Research output: Contribution to journal › Journal article › Research › peer-review
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Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study
Milne, R. L., Gaudet, M. M., Spurdle, A. B., Fasching, P. A., Couch, F. J., Benítez, J., Arias Pérez, J. I., Zamora, M. P., Malats, N., Dos Santos Silva, I., Gibson, L. J., Fletcher, O., Johnson, N., Anton-Culver, H., Ziogas, A., Figueroa, J., Brinton, L., Sherman, M. E., Lissowska, J., Hopper, J. L. & 31 others, , 1 Jan 2010, In: Breast Cancer Research (Online Edition). 12, 6, p. R110Research output: Contribution to journal › Journal article › Research › peer-review
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Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score
Minh-Phuong Huynh-Le, Karunamuni, R., Fan, C. C., Asona, L., Thompson, W. K., Martinez, M. E., Eeles, R. A., Kote-Jarai, Z., Muir, K. R., Lophatananon, A., Schleutker, J., Pashayan, N., Batra, J., Groenberg, H., Neal, D. E., Nordestgaard, B. G., Tangen, C. M., MacInnis, R. J., Wolk, A., Albanes, D. & 37 others, , 2022, In: Prostate Cancer and Prostatic Diseases. 25, p. 755–761 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Stroke genetics informs drug discovery and risk prediction across ancestries
Mishra, A., Malik, R., Hachiya, T., Jürgenson, T., Namba, S., Posner, D. C., Kamanu, F. K., Koido, M., Le Grand, Q., Shi, M., He, Y., Georgakis, M. K., Caro, I., Krebs, K., Liaw, Y. C., Vaura, F. C., Lin, K., Winsvold, B. S., Srinivasasainagendra, V., Parodi, L. & 45 others, , 2022, In: Nature. 611, 7934, p. 115-123 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Diminishing benefits of urban living for children and adolescents’ growth and development
Mishra, A., Zhou, B., Rodriguez-Martinez, A., Bixby, H., Baker, J. L., Afzal, S., Allin, K., Andersen, L. B., Ängquist, L., Jørgensen, M. B., Bjerregaard, P., Bojesen, S. E., Christensen, K., Damsgaard, C. T., Dantoft, T. M., Eliasen, M., Eriksen, L., Halkjær, J., Giwercman, A., Jørgensen, T. & 19 others, , 2023, In: Nature. 615, 7954, p. 874-883 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased Plasma Ferritin Concentration and Low-Grade Inflammation-A Mendelian Randomization Study
Moen, I. W., Bergholdt, H. K. M., Mandrup-Poulsen, Thomas, Nordestgaard, Børge & Ellervik, Christina, 2018, In: Clinical Chemistry. 64, 2, p. 374-385 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipoprotein(a) and risk of type 2 diabetes
Mora, S., Kamstrup, P. R., Rifai, N., Nordestgaard, Børge, Buring, J. E., Ridker, P. M., Mora, S., Rifai, N., Buring, J. E. & Ridker, P. M., Aug 2010, In: Clinical Chemistry. 56, 8, p. 1252-60 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On-treatment non-high-density lipoprotein cholesterol, apolipoprotein B, triglycerides, and lipid ratios in relation to residual vascular risk after treatment with potent statin therapy: JUPITER (justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin)
Mora, S., Glynn, R. J., Boekholdt, S. M., Nordestgaard, Børge, Kastelein, J. J. P. & Ridker, P. M., 2012, In: Journal of the American College of Cardiology. 59, 17, p. 1521-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment
NBCS Collaborators, N. C., ABCTB Investigators, A. I. & kConFab Investigators, K. I., 18 Aug 2021, In: Breast cancer research : BCR. 23, 1, 18 p., 86.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Breast cancer risk factors and survival by tumor subtype: Pooled analyses from the breast cancer association consortium
Morra, A., Jung, A. Y., Behrens, S., Keeman, R., Ahearn, T. U., Anton-Culver, H., Arndt, V., Augustinsson, A., Auvinen, P. K., Beane Freeman, L. E., Becher, H., Beckmann, M. W., Blomqvist, C., Bojesen, S. E., Bolla, M. K., Brenner, H., Briceno, I., Brucker, S. Y., Camp, N. J., Campa, D. & 32 others, , 2021, In: Cancer Epidemiology Biomarkers and Prevention. 30, 4, p. 623-642 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Primary Prevention With Statins: ACC/AHA Risk-Based Approach Versus Trial-Based Approaches to Guide Statin Therapy
Mortensen, M. B., Afzal, Shoaib, Nordestgaard, Børge & Falk, E., 22 Dec 2015, In: Journal of the American College of Cardiology. 66, 24, p. 2699-2709 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The high-density lipoprotein-adjusted SCORE model worsens SCORE-based risk classification in a contemporary population of 30,824 Europeans: the Copenhagen General Population Study
Mortensen, M. B., Afzal, Shoaib, Nordestgaard, Børge & Falk, E., 21 Sep 2015, In: European Heart Journal. 36, 36, p. 2446-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated LDL cholesterol and increased risk of myocardial infarction and atherosclerotic cardiovascular disease in individuals aged 70–100 years: a contemporary primary prevention cohort
Mortensen, M. B. & Nordestgaard, Børge, 2020, In: Lancet. 396, 10263, p. 1644-1652 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Guidelines versus trial-evidence for statin use in primary prevention: The Copenhagen General Population Study
Mortensen, M. B. & Nordestgaard, Børge, 2022, In: Atherosclerosis. 341, p. 20-26 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
2019 vs. 2016 ESC/EAS statin guidelines for primary prevention of atherosclerotic cardiovascular disease
Mortensen, M. B. & Nordestgaard, Børge, 2020, In: European Heart Journal. 41, 31, p. 3005-3015 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statin Eligibility for Primary Prevention of Cardiovascular Disease According to 2021 European Prevention Guidelines Compared with Other International Guidelines
Mortensen, M. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2022, In: JAMA Cardiology. 7, 8, p. 836-843Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Eligibility and Preventive Potential for New Evidence-Based Cardiovascular Drugs in Secondary Prevention
Mortensen, M. B., Blaha, M. J. & Nordestgaard, Børge, Jan 2020, In: JAMA Cardiology. 5, 2, p. 209-215Research output: Contribution to journal › Review › Research › peer-review
- Published
ACC/AHA guidelines superior to ESC/EAS guidelines for primary prevention with statins in non-diabetic Europeans: The Copenhagen General Population Study
Mortensen, M. B., Nordestgaard, Børge, Afzal, Shoaib & Falk, E., 2017, In: European Heart Journal. 38, 8, p. 586-594Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of Five Major Guidelines for Statin Use in Primary Prevention in a Contemporary General Population
Mortensen, M. B. & Nordestgaard, Børge, 2018, In: Annals of Internal Medicine. 168, 2, p. 85-92 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statin Use in Primary Prevention of Atherosclerotic Cardiovascular Disease According to 5 Major Guidelines for Sensitivity, Specificity, and Number Needed to Treat
Mortensen, M. B. & Nordestgaard, Børge, 2019, In: JAMA Cardiology. 4, 11, p. 1131-1138Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic Syndrome in Male Survivors of Pediatric Allogeneic Hematopoietic Stem Cell Transplantation: Impact of Total Body Irradiation, Low-Grade Inflammation, and Hypogonadism
Muhic, E., Mathiesen, S., Nielsen, M. M., Suominen, A., Sørensen, K., Ifversen, M., Nolsöe, R. L., Pedersen, K. M., Lähteenmäki, P., Nordestgaard, Børge, Juul, Anders, Jahnukainen, K. & Muller, Klaus, 2021, In: Transplantation and Cellular Therapy. 27, 9, p. 778.e1-778.e8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reference equations for pulmonary diffusing capacity of carbon monoxide and nitric oxide in adult Caucasians
Munkholm, M., Marott, J. L., Bjerre-Kristensen, L., Madsen, F., Pedersen, O. F., Lange, Peter, Nordestgaard, Børge & Mortensen, Jann, 2018, In: European Respiratory Journal. 52, 1, 14 p., 1500677.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The BioImage Study: novel approaches to risk assessment in the primary prevention of atherosclerotic cardiovascular disease--study design and objectives
Muntendam, P., McCall, C., Sanz, J., Falk, E., Fuster, V., Sillesen, H. H., High-Risk Plaque Initiative, H. P. I. & Nordestgaard, Børge, 1 Jul 2010, In: American Heart Journal. 160, 1, p. 49-57.e1 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium
Muranen, T. A., Blomqvist, C., Dörk, T., Jakubowska, A., Heikkilä, P., Fagerholm, R., Greco, D., Aittomäki, K., Bojesen, S. E., Shah, M., Dunning, A. M., Rhenius, V., Hall, P., Czene, K., Brand, J. S., Darabi, H., Chang-Claude, J., Rudolph, A., Nordestgaard, B. G., Couch, F. J. & 24 others, , 3 Oct 2016, In: Breast Cancer Research (Online). 18, 15 p., 98.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic modifiers of CHEK2*1100delC-associated breast cancer risk
Muranen, T. A., Greco, D., Blomqvist, C., Aittomäki, K., Khan, S., Hogervorst, F., Verhoef, S., Pharoah, P. D. P., Dunning, A. M., Shah, M., Luben, R., Bojesen, S. E., Nordestgaard, B. G., Schoemaker, M., Swerdlow, A., García-Closas, M., Figueroa, J., Dörk, T., Bogdanova, N. V., Hall, P. & 56 others, , 2017, In: Genetics In Medicine. 19, 5, p. 599-603Research output: Contribution to journal › Letter › Research › peer-review
- Published
Serum soluble CD163 predicts risk of type 2 diabetes in the general population
Møller, H. J., Frikke-Schmidt, Ruth, Moestrup, S., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 1 Feb 2011, In: Clinical Chemistry. 57, 2, p. 291-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Normal values of myocardial blood flow measured with dynamic myocardial CT perfusion
Møller, M. B., Linde, J. J., Fuchs, A., Køber, Lars Valeur, Nordestgaard, Børge & Kofoed, Klaus Fuglsang, 2024, (E-pub ahead of print) In: European heart journal. Cardiovascular Imaging. jeae050.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors
Nickels, S., Truong, T., Hein, R., Stevens, K., Buck, K., Behrens, S., Eilber, U., Schmidt, M., Häberle, L., Vrieling, A., Gaudet, M., Figueroa, J., Schoof, N., Spurdle, A. B., Rudolph, A., Fasching, P. A., Hopper, J. L., Makalic, E., Schmidt, D. F., Southey, M. C. & 31 others, , Mar 2013, In: P L o S Genetics (Online). 9, 3, p. e1003284Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diagnostic value of JAK2 V617F somatic mutation for myeloproliferative cancer in 49 488 individuals from the general population
Nielsen, C., Birgens, H. S., Nordestgaard, Børge & Bojesen, Stig Egil, 2013, In: British Journal of Haematology. 160, 1, p. 70-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
JAK2V617F Somatic Mutation In The General Population: Myeloproliferative Neoplasm Development And Progression Rate
Nielsen, C., Bojesen, Stig Egil, Nordestgaard, Børge, Kofoed, K. F. & Birgens, H. S., Sep 2014, In: Haematologica. 99, 9, p. 1448-1455 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The JAK2 V617F somatic mutation, mortality and cancer risk in the general population
Nielsen, C., Birgens, H. S., Nordestgaard, Børge, Kjaer, L. & Bojesen, Stig Egil, 2011, In: Acta Haematologica Polonica. 96, 3, p. 450-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
P-wave duration and the risk of atrial fibrillation: Results from the Copenhagen ECG Study
Nielsen, J. B., Kühl, J. T., Pietersen, A., Graff, C., Lind, B., Struijk, J. J., Olesen, M. S., Sinner, M. F., Bachmann, T. N., Haunsø, Stig, Nordestgaard, Børge, Ellinor, P. T., Svendsen, Jesper Hastrup, Kofoed, Klaus Fuglsang, Køber, Lars Valeur & Holst, A. G., Sep 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 9, p. 1887-95 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low Plasma Adiponectin in Risk of Type 2 Diabetes: Observational Analysis and One- and Two-Sample Mendelian Randomization Analyses in 756,219 Individuals
Nielsen, M. B., Çolak, Y., Benn, Marianne & Nordestgaard, Børge, 2021, In: Diabetes. 70, 11, p. 2694-2705 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma adiponectin and risk of asthma: observational analysis, genetic Mendelian randomisation and meta-analysis
Nielsen, M. B., Nordestgaard, Børge, Benn, Marianne & colak, Y., 2022, In: Thorax. 77, 11, p. 1070–1077 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma adiponectin levels and risk of heart failure, atrial fibrillation, aortic valve stenosis, and myocardial infarction: large-scale observational and Mendelian randomization evidence
Nielsen, M. B., Çolak, Y., Benn, Marianne, Mason, A., Burgess, S. & Nordestgaard, Børge, 2024, In: Cardiovascular Research. 120, 1, p. 95-107 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Causal Relationship between Plasma Adiponectin and Body Mass Index: One- and Two-Sample Bidirectional Mendelian Randomization Analyses in 460 397 Individuals
Nielsen, M. B., Çolak, Y., Benn, Marianne & Nordestgaard, Børge, 2020, In: Clinical Chemistry. 66, 12, p. 1548-1557Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Significance of lipids, lipoproteins, and apolipoproteins during the first 14–16 months of life
Nielsen, S. T., Lytsen, R. M., Strandkjær, N., Rasmussen, I. J., Sillesen, A. S., B. Vøgg, R. O., Raja, A. A., Nordestgaard, Børge, Kamstrup, P. R., Iversen, Kasper, Bundgård, Henning, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 42, p. 4408-4418 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risk of thyroid cancer, brain cancer, and non-Hodgkin lymphoma after adult leukemia: a nationwide study
Nielsen, S. F., Bojesen, Stig Egil, Birgens, H. S. & Nordestgaard, Børge, 2011, In: Blood. 118, 15, p. 4062-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statin use before diabetes diagnosis and risk of microvascular disease: a nationwide nested matched study
Nielsen, S. F. & Nordestgaard, Børge, Nov 2014, In: The Lancet Diabetes & Endocrinology. 2, 11, p. 894-900 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statin use and reduced cancer-related mortality
Nielsen, S. F., Nordestgaard, Børge & Bojesen, S. E., 2012, In: New England Journal of Medicine. 367, 19, p. 1792-802 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations between first and second primary cancers: a population-based study
Nielsen, S. F., Nordestgaard, Børge & Bojesen, S. E., 2012, In: C M A J. 184, 1, p. E57-69Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cancerpatienter bør ikke behandles med statiner. Svar
Nielsen, S. F., Nordestgaard, Børge & Bojesen, S. E., 7 Jan 2013, In: Ugeskrift for Laeger. 175, 1-2, p. 76Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated rheumatoid factor and long term risk of rheumatoid arthritis: a prospective cohort study
Nielsen, S. F., Bojesen, S. E., Schnohr, P. & Nordestgaard, Børge, 2012, In: B M J. 345, p. e5244Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Negative statin-related news stories decrease statin persistence and increase myocardial infarction and cardiovascular mortality: a nationwide prospective cohort study
Nielsen, S. F. & Nordestgaard, Børge, 14 Mar 2016, In: European Heart Journal. 37, 11, p. 908-16 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Venous thromboembolism associated with severe dyspnoea and asthma in 102 792 adults
Nilausen, K. F., Landt, E. M., Al-Shuweli, S., Nordestgaard, Børge, Bødtger, U. & Dahl, Morten, 2023, In: ERJ Open Research. 9, 6, 8 p., 00631-2023.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ECG and CT for the detection of left atrial enlargement in hypertensive individuals—a population-based study
Nilsson, E. J. P., Kühl, J. T., Nielsen, J. B., Fuchs, A., Knudsen, A. D., Sigvardsen, P. E., Graff, C., Køber, Lars Valeur, Nordestgaard, Børge & Kofoed, Klaus Fuglsang, 2022, In: Hypertension Research. 45, 8, p. 1382-1391Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipoprotein(a) levels in a global population with established atherosclerotic cardiovascular disease
Nissen, S. E., Wolski, K., Cho, L., Nicholls, S. J., Kastelein, J., Leitersdorf, E., Landmesser, U., Blaha, M., Lincoff, A. M., Morishita, R., Tsimikas, S., Liu, J., Manning, B., Kozlovski, P., Lesogor, A., Thuren, T., Shibasaki, T., Matei, F., Silveira, F. S., Meunch, A. & 4 others, , 2022, In: Open Heart. 9, 2, 002060.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coffee intake protects against symptomatic gallstone disease in the general population: a Mendelian randomization study
Nordestgaard, A. T., Stender, Stefan, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2020, In: Journal of Internal Medicine. 287, 1, p. 42-53Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Self-reported and genetically predicted coffee consumption and smoking in dementia: A Mendelian randomization study
Nordestgaard, A. T., Nordestgaard, Børge, Frikke-Schmidt, Ruth, Juul Rasmussen, I. & Bojesen, Stig Egil, 2022, In: Atherosclerosis. 348, p. 36-43 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coffee intake and risk of obesity, metabolic syndrome and type 2 diabetes: a Mendelian randomization study
Nordestgaard, A. T., Thomsen, M. & Nordestgaard, Børge, Apr 2015, In: International Journal of Epidemiology. 44, 2, p. 551-65 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coffee intake, cardiovascular disease and allcause mortality: Observational and mendelian randomization analyses in 95 000-223 000 individuals
Nordestgaard, A. T. & Nordestgaard, Børge, 2016, In: International Journal of Epidemiology. 45, 6, p. 1938-1952 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11241
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RAD51B in Familial Breast Cancer
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Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci
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Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study
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