Bo Torben Porse
Professor, Clinical Professor
Porse Group
Københavns Universitet, BRIC, Ole Maaløes Vej 5
2200 København N
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Member of:
Internal Medicine: Haematology
- 2006
- Published
The proline-histidine-rich CDK2/CDK4 interaction region of C/EBPalpha is dispensable for C/EBPalpha-mediated growth regulation in vivo.
Porse, Bo Torben, Pedersen, T. A., Hasemann, M. S., Schuster, Mikkel Bruhn, Kirstetter, P., Luedde, T., Damgaard, I., Kurz, E., Schjerling, C. K. & Nerlov, C., 2006, In: Molecular and Cellular Biology. 26, 3, p. 1028-37 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Highly glycosylated alpha1-acid glycoprotein is synthesized in myelocytes, stored in secondary granules, and released by activated neutrophils.
Theilgaard-Mønch, Kim, Jacobsen, L. C., Rasmussen, T., Niemann, C. U., Udby, L., Borup, R., Gharib, M., Arkwright, P. D., Gombart, A. F., Calafat, J., Porse, Bo Torben & Borregaard, N., 2005, In: Journal of Leukocyte Biology. 78, 2, p. 462-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage.
Porse, Bo Torben, Bryder, D., Theilgaard-Mønch, Kim, Hasemann, M. S., Anderson, K., Damgaard, I., Jacobsen, S. E. W. & Nerlov, C., 2005, In: Journal of Experimental Medicine. 202, 1, p. 85-96 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Messenger RNA surveillance: neutralizing natural nonsense.
Weischenfeldt, Joachim Lütken, Lykke-Andersen, J. & Porse, Bo Torben, 2005, In: Current Biology. 15, 14, p. R559-62Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems biology of neutrophil differentiation and immune response.
Theilgaard-Mønch, Kim, Porse, Bo Torben & Borregaard, N., 2005, In: Current Opinion in Immunology. 18, 1, p. 54-60 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
A novel partial modification at C2501 in Escherichia coli 23S ribosomal RNA
Andersen, T., Porse, Bo Torben & Kirpekar, F., 1 Jun 2004, In: RNA. 10, 6, p. 907-913 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
A conserved chloramphenicol binding site at the entrance to the ribosomal peptide exit tunnel.
Long, K. S. & Porse, Bo Torben, 2003, In: Nucleic Acids Research. 31, 24, p. 7208-15 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transgene mus som sygdomsmodeller.
Schuster, Mikkel Bruhn & Porse, Bo Torben, 2003, In: Ugeskrift for læger. 165, 8, p. 793-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo.
Porse, Bo Torben, Pedersen TA, Xu, X., Lindberg, B., Wewer, Ulla M., Friis-Hansen, L. & Nerlov, C., 2001, In: Cell. 107, 2, p. 247-58 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
Puromycin-rRNA interaction sites at the peptidyl transferase center
Rodriguez-Fonseca, C., Phan, H., Long, K. S., Porse, Bo Torben, Kirilov, S. V., Amils, R. & Garrett, Roger Antony, 2000, In: RNA: A publication of the RNA Society. 6, 5, p. 744-754 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Direct crosslinking of the antitumor antibiotic sparsomycin, and its derivatives, to A2602 in the peptidyl transferase center of 23S-like rRNA within ribosome-tRNA complexes.
Porse, Bo Torben, Kirillov, S. V., Awayez, M. J., Ottenheijm, H. C. & Garrett, R. A., 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, 16, p. 9003-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptidyl transferase antibiotics perturb the relative positioning of the 3'-terminal adenosine of P/P'-site-bound tRNA and 23S rRNA in the ribosome
Kirillov, S. V., Porse, Bo Torben & Garrett, R. A., 1999, In: RNA: A publication of the RNA Society. 5, 8, p. 1003-13 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ribosomal mechanics, antibiotics, and GTP hydrolysis.
Porse, Bo Torben & Garrett, R. A., 1999, In: Cell. 97, 4, p. 423-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sites of interaction of streptogramin A and B antibiotics in the peptidyl transferase loop of 23 S rRNA and the synergism of their binding mechanisms
Porse, Bo Torben & Garrett, Roger Antony, 1999, In: Journal of Molecular Biology. 286, p. 375-387Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sites of interaction of streptogramin A and B antibiotics in the peptidyl transferase loop of 23 S rRNA and the synergism of their inhibitory mechanisms.
Porse, Bo Torben & Garrett, R. A., 1999, In: Journal of Molecular Biology. 286, 2, p. 375-87 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The antibiotic micrococcin acts on protein L11 at the ribosomal GTPase centre.
Porse, Bo Torben, Cundliffe, E. & Garrett, Roger Antony, 1999, In: Journal of Molecular Biology. 287, 1, p. 33-45 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UV-induced modifications in the peptidyl transferase loop of 23S rRNA dependent on binding of the streptogramin B antibiotic, pristinamycin IA.
Porse, Bo Torben, Kirillov, S. V., Awayez, M. J. & Garrett, R. A., 1999, In: RNA: A publication of the RNA Society. 5, 4, p. 585-95 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Assembly of proteins and 5S rRNA to transcripts of the major structural domains of 23S rRNA
Østergaard, P., Phan, H., Johansen, L. B., Egebjerg, J., Østergaard, L., Porse, Bo Torben & Garrett, Roger Antony, 1 Nov 1998, In: Journal of Molecular Biology. 284, 2, p. 227-240 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The antibiotic thiostrepton inhibits a functional transition within protein L11 at the ribosomal GTPase centre
Porse, Bo Torben, Leviev, I., Mankin, A. S. & Garrett, R. A., 1998, In: Journal of Molecular Biology. 276, 2, p. 391-404 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
Movement of the 3'-end of tRNA through the peptidyl transferase centre and its inhibition by antibiotics
Kirillov, S., Porse, Bo Torben, Vester, B., Woolley, P. & Garrett, Roger Antony, 1997, In: FEBS Letters. 406, 3, p. 223-233 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
- Published
A sparsomycin-resistant mutant of Halobacterium salinarium lacks a modification at nucleotide U2603 in the peptidyl transferase centre of 23 S rRNA
Lázaro, E., Rodriguez-Fonseca, C., Porse, Bo Torben, Ureña, D., Garrett, Roger Antony & Ballesta, J. P. G., 16 Aug 1996, In: Journal of Molecular Biology. 261, 2, p. 231-238 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic inhibition of the movement of tRNA substrates through a peptidyl transferase cavity.
Porse, Bo Torben, Rodriguez-Fonseca, C., Leviev, I. & Garrett, R. A., 1996, In: Biochemistry and Cell Biology. 73, 11-12, p. 877-85 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The donor substrate site within the peptidyl transferase loop of 23 S rRNA and its putative interactions with the CCA-end of N-blocked aminoacyl-tRNA(Phe).
Porse, Bo Torben, Thi-Ngoc, H. P. & Garrett, R. A., 1996, In: Journal of Molecular Biology. 264, 3, p. 472-83 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Mapping important nucleotides in the peptidyl transferase centre of 23 S rRNA using a random mutagenesis approach.
Porse, Bo Torben & Garrett, R. A., 1995, In: Journal of Molecular Biology. 249, 1, p. 1-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4985646
Most downloads
-
3483
downloads
spliceR: an R package for classification of alternative splicing and prediction of coding potential from RNA-seq data
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2749
downloads
Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2491
downloads
HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
Research output: Contribution to journal › Journal article › Research › peer-review
Published