Bo Torben Porse

Bo Torben Porse

Professor, Clinical Professor

Member of:

  • Internal Medicine: Haematology


  1. 2024
  2. Published

    BloodSpot 3.0: a database of gene and protein expression data in normal and malignant haematopoiesis

    Gíslason, M. H., Demircan, G. S., Prachar, Marek, Furtwängler, Benjamin, Schwaller, J., Schoof, E., Porse, Bo Torben, Rapin, N. & Bagger, F., 2024, In: Nucleic acids symposium series. 52, D1, p. D1138–D1142 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells

    Ghiasi, S. M., Marchetti, P., Piemonti, L., Nielsen, Jens Høiriis, Porse, Bo Torben, Mandrup-Poulsen, Thomas & Rutter, G. A., 2024, In: Frontiers in Endocrinology. 15, 13 p., 1359147.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2023
  5. Published

    Overall Survival in Patients with Ccus Depends on Presence of Anemia

    Træden, D., Tulstrup, Morten Rytter, Johansen, Morten Munk, mxz703, mxz703, Marcher, C., Raaschou-jensen, K., Stidsholt Roug, A., Severinsen, M. T., Porse, Bo Torben, Theilgaard-Mønch, Kim, Jespersen, J., Cowland, J. B., Sjö, Lene Dissing, Andersen, M. K., Grønbæk, Kirsten & Hansen, Jakob Werner, 28 Nov 2023, In: Blood. 142, Supplement 1, p. 1864-1864

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression

    Heyes, E., Wilhelmson, Anna, Wenzel, Anne, Manhart, G., Eder, T., Schuster, Mikkel Bruhn, Rzepa, E., Pundhir, Sachin, D’Altri, T., Frank, Anne-Katrine, Gentil, C., Woessmann, J., Schoof, E. M., Meggendorfer, M., Schwaller, J., Haferlach, T., Grebien, F. & Porse, Bo Torben, 2023, In: Nature Communications. 14, 18 p., 6185.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    ERG Functionally Overlaps with Other Ets Proteins in Promoting TH9 Cell Expression of IL9 during Allergic Lung Inflammation

    Kharwadkar, R., Ulrich, B. J., Chu, M., Koh, B., Hufford, M. M., Fu, Y., Birdsey, G. M., Porse, Bo Torben, Randi, A. M. & Kaplan, M. H., 2023, In: Journal of Immunology. 210, 5, p. 537-546

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Exploration of cell state heterogeneity using single-cell proteomics through sensitivity-tailored data-independent acquisition

    Petrosius, V., Aragon-Fernandez, P., Üresin, Nil, Kovacs, G., Phlairaharn, T., Furtwängler, Benjamin, Op De Beeck, J., Skovbakke, S. L., Goletz, S., Thomsen, Simon Francis, Keller, U. A. D., Natarajan, K. N., Porse, Bo Torben & Schoof, E. M., 2023, In: Nature Communications. 14, 16 p., 5910.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Inter and transgenerational impact of H3K4 methylation in neuronal homeostasis

    Nørgaard, Steffen, Tapia, Marta Cecylia, Zeijdner, Mandoh Johannes Seydin, Kim, J. H., Won, K. J., Porse, Bo Torben & Salcini, Anna Elisabetta, 2023, In: Life Science Alliance. 6, 8, 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    LEP promoter methylation in the initiation and progression of clonal cytopenia of undetermined significance and myelodysplastic syndrome

    Kaastrup, K., Gillberg, Linn, Mikkelsen, Stine Ulrik, mxz703, mxz703, Schöllkopf, C., Mortensen, B. K., Porse, Bo Torben, Hansen, Jakob Werner & Grønbæk, Kirsten, 2023, In: Clinical Epigenetics. 15, 13 p., 91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes

    Trempenau, M. L., Schuster, Mikkel Bruhn, Pundhir, Sachin, Araújo Pereira, Mafalda, Kalvisa, A., Tapia, Marta Cecylia, Su, Jinyu, Ge, Y., de Boer, Bauke, Balhuizen, Alexander, Bagger, F. O., Shliaha, P., Sroczynska, P., Walfridsson, J., Grønbæk, Kirsten, Theilgaard-Mønch, Kim, Jensen, O. N., Helin, K. & Porse, Bo Torben, 2023, In: Leukemia. 37, 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The impact of SWI/SNF and NuRD inactivation on gene expression is tightly coupled with levels of RNA polymerase II occupancy at promoters

    Pundhir, Sachin, Su, Jinyu, Tapia, Marta Cecylia, Hansen, A. M., Haile, James Seymour, Hansen, K. & Porse, Bo Torben, 2023, In: Genome Research. 33, 3, p. 332-345 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2022
  14. Published

    Dynamic intron retention modulates gene expression in the monocytic differentiation pathway

    Song, R., Tikoo, S., Jain, R., Pinello, N., Au, A. Y. M., Nagarajah, R., Porse, Bo Torben, Rasko, J. E. J. & J.-L. Wong, J., 2022, In: Immunology. 165, 2, p. 274-286

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis

    Grigoryan, A., Zacharaki, D., Balhuizen, A., Côme, C. R., Garcia, A. G., Hidalgo Gil, D., Frank, A. K., Aaltonen, K., Mañas, A., Esfandyari, J., Kjellman, P., Englund, E., Rodriguez, C., Sime, W., Massoumi, R., Kalantari, N., Prithiviraj, S., Li, Y., Dupard, S. J., Isaksson, H. & 4 others, Madsen, C. D., Porse, Bo Torben, Bexell, D. & Bourgine, P. E., 2022, In: Science Translational Medicine. 14, 666, 16 p., eabm6391.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway

    Hansen, A. M., Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Jakobsen, J. S., Kalvisa, A., Tapia, Marta Cecylia, Gordon, Sandra, Ambri, F., Bagger, F. O., Pandey, D., Helin, K. & Porse, Bo Torben, 2022, In: Science Advances. 8, 11, eabf8627.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target

    Vanner, R. J., Dobson, S. M., Gan, O. I., McLeod, J., Schoof, E. M., Grandal, I., Wintersinger, J. A., Garcia-Prat, L., Hosseini, M., Xie, S. Z., Jin, L., Mbong, N., Voisin, V., Chan-Seng-Yue, M., Kennedy, J. A., Waanders, E., Morris, Q., Porse, B., Chan, S. M., Guidos, C. J. & 4 others, Danska, J. S., Minden, M. D., Mullighan, C. G. & Dick, J. E., 2022, In: Blood cancer discovery. 3, 1, p. 16-31 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    PTBP1 promotes hematopoietic stem cell maintenance and red blood cell development by ensuring sufficient availability of ribosomal constituents

    Rehn, M., Wenzel, Anne, Frank, Anne-Katrine, Schuster, Mikkel Bruhn, Pundhir, Sachin, Jørgensen, N., Vitting-Seerup, K., Ge, Y., Jendholm, J., Michaut, Magali, Schoof, E. M., Jensen, T. L., Rapin, N., Sapio, R. T., Andersen, Kasper Langebjerg, Lund, Anders H., Solimena, M., Holzenberger, M., Pestov, D. G. & Porse, Bo Torben, 2022, In: Cell Reports. 39, 6, 28 p., 110793.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Progression of the pluripotent epiblast depends upon the NMD factor UPF2

    Chousal, J. N., Sohni, A., Vitting-Seerup, K., Cho, K., Kim, M., Tan, K., Porse, Bo Torben, Wilkinson, M. F. & Cook-Andersen, H., 2022, In: Development. 149, 21, 15 p., dev200764.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Real-Time Search Assisted Acquisition on a Tribrid Mass Spectrometer Improves Coverage in Multiplexed Single-Cell Proteomics

    Furtwängler, Benjamin, Üresin, Nil, Motamedchaboki, K., Huguet, R., Lopez-Ferrer, D., Zabrouskov, V., Porse, Bo Torben & Schoof, E. M., 2022, In: Molecular and Cellular Proteomics. 21, 4, 100219.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Therapeutic Potential of an Immune-Modulatory Vaccination Targeting Myeloid-Derived Suppressor Cells in Myelodysplastic Syndrome

    Bentivegna, Sofia, Holmstrøm, M., Balhuizen, Alexander, Almosailleakh, M., Perez Penco, Maria, Porse, Bo Torben, Andersen, Mads Hald & Grønbæk, Kirsten, 2022, In: Blood. 140, Suppl. 1, p. 4007-4008 2 p.

    Research output: Contribution to journalConference abstract in journalResearch

  22. Published

    Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation: In memoriam Professor Niels Borregaard

    Theilgaard-Mønch, Kim, Pundhir, Sachin, Reckzeh, K., Su, Jinyu, Tapia, Marta Cecylia, Furtwängler, Benjamin, Jendholm, J., Jakobsen, J. S., Hasemann, M. S., Knudsen, K. J., Cowland, J. B., Fossum, A., Schoof, E., Schuster, Mikkel Bruhn & Porse, Bo Torben, 2022, In: Nature Communications. 13, 1, 17 p., 3595.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2021
  24. Published

    Quantitative single-cell proteomics as a tool to characterize cellular hierarchies

    Schoof, E. M., Furtwängler, Benjamin, Üresin, Nil, Rapin, N., Savickas, S., Gentil, C., Lechman, E., Keller, U. A. D., Dick, J. E. & Porse, Bo Torben, 7 Jun 2021, In: Nature Communications. 12, 1, p. 3341

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Basement membrane stiffness determines metastases formation

    Reuten, R., Zendehroud, S., Nicolau, M., Fleischhauer, L., Laitala, A., Kiderlen, S., Nikodemus, D., Wullkopf, L., Nielsen, S. R., Mcneilly, S., Prein, C., Rafaeva, M., Schoof, E. M., Furtwängler, B., Porse, B. T., Kim, H., Won, K. J., Sudhop, S., Zornhagen, K. W., Suhr, F. & 11 others, Maniati, E., Pearce, O. M. T., Koch, M., Oddershede, L. B., Van Agtmael, T., Madsen, C. D., Mayorca Guiliani, Alejandro Enrique, Bloch, W., Netz, R. R., Clausen-schaumann, H. & Erler, Janine, 2021, In: Nature Materials. 20, p. 892–903

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy

    Estruch Alrich, Montserrat, Reckzeh, K., Vittori, Camilla, Centio, A., Ali, M., Engelhard, Sophia Manon Charlotte, Zhao, L., Won, K. J., Liu, P., Porse, Bo Torben & Theilgaard-Mønch, Kim, 2021, In: Leukemia. 35, p. 2030-2042

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The ASXL1-G643W variant accelerates the development of CEBPA mutant acute myeloid leukemia

    D'Altri, T., Wilhelmson, Anna, Schuster, Mikkel Bruhn, Wenzel, Anne, Kalvisa, A., Pundhir, Sachin, Hansen, A. M. & Porse, Bo Torben, 2021, In: Haematologica. 106, 4, p. 1000-1007 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The eha research roadmap: normal hematopoiesis

    Jaffredo, T., Balduini, A., Bigas, A., Bernardi, R., Bonnet, D., Canque, B., Charbord, P., Cumano, A., Delwel, R., Durand, C., Fibbe, W., Forrester, L., De Franceschi, L., Ghevaert, C., Gjertsen, B., Gottgens, B., Graf, T., Heidenreich, O., Hermine, O., Higgs, D. & 21 others, Kleanthous, M., Klump, H., Kouskoff, V., Krause, D., Lacaud, G., Lo Celso, C., Martens, J. H. A., Méndez-Ferrer, S., Menendez, P., Oostendorp, R., Philipsen, S., Porse, Bo Torben, Raaijmakers, M., Robin, C., Stunnenberg, H., Theilgaard-Mønch, Kim, Touw, I., Vainchenker, W., Corrons, J. L. V., Yvernogeau, L. & Schuringa, J. J., 2021, In: HemaSphere. 5, 12, e669.

    Research output: Contribution to journalReviewResearchpeer-review

  29. 2020
  30. Published

    CCAAT enhancer binding protein alpha (CEBPA) biallelic acute myeloid leukaemia: cooperating lesions, molecular mechanisms and clinical relevance

    Wilhelmson, Anna & Porse, Bo Torben, 2020, In: British Journal of Haematology. 190, 4, p. 495-507

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 4985646