Bo Torben Porse
Professor, Clinical Professor
Porse Group
Københavns Universitet, BRIC, Ole Maaløes Vej 5
2200 København N
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Member of:
Internal Medicine: Haematology
- 2024
- Published
BloodSpot 3.0: a database of gene and protein expression data in normal and malignant haematopoiesis
Gíslason, M. H., Demircan, G. S., Prachar, Marek, Furtwängler, Benjamin, Schwaller, J., Schoof, E., Porse, Bo Torben, Rapin, N. & Bagger, F., 2024, In: Nucleic acids symposium series. 52, D1, p. D1138–D1142 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells
Ghiasi, S. M., Marchetti, P., Piemonti, L., Nielsen, Jens Høiriis, Porse, Bo Torben, Mandrup-Poulsen, Thomas & Rutter, G. A., 2024, In: Frontiers in Endocrinology. 15, 13 p., 1359147.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Overall Survival in Patients with Ccus Depends on Presence of Anemia
Træden, D., Tulstrup, Morten Rytter, Johansen, Morten Munk, mxz703, mxz703, Marcher, C., Raaschou-jensen, K., Stidsholt Roug, A., Severinsen, M. T., Porse, Bo Torben, Theilgaard-Mønch, Kim, Jespersen, J., Cowland, J. B., Sjö, Lene Dissing, Andersen, M. K., Grønbæk, Kirsten & Hansen, Jakob Werner, 28 Nov 2023, In: Blood. 142, Supplement 1, p. 1864-1864Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression
Heyes, E., Wilhelmson, Anna, Wenzel, Anne, Manhart, G., Eder, T., Schuster, Mikkel Bruhn, Rzepa, E., Pundhir, Sachin, D’Altri, T., Frank, Anne-Katrine, Gentil, C., Woessmann, J., Schoof, E. M., Meggendorfer, M., Schwaller, J., Haferlach, T., Grebien, F. & Porse, Bo Torben, 2023, In: Nature Communications. 14, 18 p., 6185.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ERG Functionally Overlaps with Other Ets Proteins in Promoting TH9 Cell Expression of IL9 during Allergic Lung Inflammation
Kharwadkar, R., Ulrich, B. J., Chu, M., Koh, B., Hufford, M. M., Fu, Y., Birdsey, G. M., Porse, Bo Torben, Randi, A. M. & Kaplan, M. H., 2023, In: Journal of Immunology. 210, 5, p. 537-546Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploration of cell state heterogeneity using single-cell proteomics through sensitivity-tailored data-independent acquisition
Petrosius, V., Aragon-Fernandez, P., Üresin, Nil, Kovacs, G., Phlairaharn, T., Furtwängler, Benjamin, Op De Beeck, J., Skovbakke, S. L., Goletz, S., Thomsen, Simon Francis, Keller, U. A. D., Natarajan, K. N., Porse, Bo Torben & Schoof, E. M., 2023, In: Nature Communications. 14, 16 p., 5910.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inter and transgenerational impact of H3K4 methylation in neuronal homeostasis
Nørgaard, Steffen, Tapia, Marta Cecylia, Zeijdner, Mandoh Johannes Seydin, Kim, J. H., Won, K. J., Porse, Bo Torben & Salcini, Anna Elisabetta, 2023, In: Life Science Alliance. 6, 8, 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
LEP promoter methylation in the initiation and progression of clonal cytopenia of undetermined significance and myelodysplastic syndrome
Kaastrup, K., Gillberg, Linn, Mikkelsen, Stine Ulrik, mxz703, mxz703, Schöllkopf, C., Mortensen, B. K., Porse, Bo Torben, Hansen, Jakob Werner & Grønbæk, Kirsten, 2023, In: Clinical Epigenetics. 15, 13 p., 91.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes
Trempenau, M. L., Schuster, Mikkel Bruhn, Pundhir, Sachin, Araújo Pereira, Mafalda, Kalvisa, A., Tapia, Marta Cecylia, Su, Jinyu, Ge, Y., de Boer, Bauke, Balhuizen, Alexander, Bagger, F. O., Shliaha, P., Sroczynska, P., Walfridsson, J., Grønbæk, Kirsten, Theilgaard-Mønch, Kim, Jensen, O. N., Helin, K. & Porse, Bo Torben, 2023, In: Leukemia. 37, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of SWI/SNF and NuRD inactivation on gene expression is tightly coupled with levels of RNA polymerase II occupancy at promoters
Pundhir, Sachin, Su, Jinyu, Tapia, Marta Cecylia, Hansen, A. M., Haile, James Seymour, Hansen, K. & Porse, Bo Torben, 2023, In: Genome Research. 33, 3, p. 332-345 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Dynamic intron retention modulates gene expression in the monocytic differentiation pathway
Song, R., Tikoo, S., Jain, R., Pinello, N., Au, A. Y. M., Nagarajah, R., Porse, Bo Torben, Rasko, J. E. J. & J.-L. Wong, J., 2022, In: Immunology. 165, 2, p. 274-286Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis
Grigoryan, A., Zacharaki, D., Balhuizen, A., Côme, C. R., Garcia, A. G., Hidalgo Gil, D., Frank, A. K., Aaltonen, K., Mañas, A., Esfandyari, J., Kjellman, P., Englund, E., Rodriguez, C., Sime, W., Massoumi, R., Kalantari, N., Prithiviraj, S., Li, Y., Dupard, S. J., Isaksson, H. & 4 others, , 2022, In: Science Translational Medicine. 14, 666, 16 p., eabm6391.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway
Hansen, A. M., Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Jakobsen, J. S., Kalvisa, A., Tapia, Marta Cecylia, Gordon, Sandra, Ambri, F., Bagger, F. O., Pandey, D., Helin, K. & Porse, Bo Torben, 2022, In: Science Advances. 8, 11, eabf8627.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target
Vanner, R. J., Dobson, S. M., Gan, O. I., McLeod, J., Schoof, E. M., Grandal, I., Wintersinger, J. A., Garcia-Prat, L., Hosseini, M., Xie, S. Z., Jin, L., Mbong, N., Voisin, V., Chan-Seng-Yue, M., Kennedy, J. A., Waanders, E., Morris, Q., Porse, B., Chan, S. M., Guidos, C. J. & 4 others, , 2022, In: Blood cancer discovery. 3, 1, p. 16-31 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PTBP1 promotes hematopoietic stem cell maintenance and red blood cell development by ensuring sufficient availability of ribosomal constituents
Rehn, M., Wenzel, Anne, Frank, Anne-Katrine, Schuster, Mikkel Bruhn, Pundhir, Sachin, Jørgensen, N., Vitting-Seerup, K., Ge, Y., Jendholm, J., Michaut, Magali, Schoof, E. M., Jensen, T. L., Rapin, N., Sapio, R. T., Andersen, Kasper Langebjerg, Lund, Anders H., Solimena, M., Holzenberger, M., Pestov, D. G. & Porse, Bo Torben, 2022, In: Cell Reports. 39, 6, 28 p., 110793.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Progression of the pluripotent epiblast depends upon the NMD factor UPF2
Chousal, J. N., Sohni, A., Vitting-Seerup, K., Cho, K., Kim, M., Tan, K., Porse, Bo Torben, Wilkinson, M. F. & Cook-Andersen, H., 2022, In: Development. 149, 21, 15 p., dev200764.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Real-Time Search Assisted Acquisition on a Tribrid Mass Spectrometer Improves Coverage in Multiplexed Single-Cell Proteomics
Furtwängler, Benjamin, Üresin, Nil, Motamedchaboki, K., Huguet, R., Lopez-Ferrer, D., Zabrouskov, V., Porse, Bo Torben & Schoof, E. M., 2022, In: Molecular and Cellular Proteomics. 21, 4, 100219.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Therapeutic Potential of an Immune-Modulatory Vaccination Targeting Myeloid-Derived Suppressor Cells in Myelodysplastic Syndrome
Bentivegna, Sofia, Holmstrøm, M., Balhuizen, Alexander, Almosailleakh, M., Perez Penco, Maria, Porse, Bo Torben, Andersen, Mads Hald & Grønbæk, Kirsten, 2022, In: Blood. 140, Suppl. 1, p. 4007-4008 2 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation: In memoriam Professor Niels Borregaard
Theilgaard-Mønch, Kim, Pundhir, Sachin, Reckzeh, K., Su, Jinyu, Tapia, Marta Cecylia, Furtwängler, Benjamin, Jendholm, J., Jakobsen, J. S., Hasemann, M. S., Knudsen, K. J., Cowland, J. B., Fossum, A., Schoof, E., Schuster, Mikkel Bruhn & Porse, Bo Torben, 2022, In: Nature Communications. 13, 1, 17 p., 3595.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Quantitative single-cell proteomics as a tool to characterize cellular hierarchies
Schoof, E. M., Furtwängler, Benjamin, Üresin, Nil, Rapin, N., Savickas, S., Gentil, C., Lechman, E., Keller, U. A. D., Dick, J. E. & Porse, Bo Torben, 7 Jun 2021, In: Nature Communications. 12, 1, p. 3341Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Basement membrane stiffness determines metastases formation
Reuten, R., Zendehroud, S., Nicolau, M., Fleischhauer, L., Laitala, A., Kiderlen, S., Nikodemus, D., Wullkopf, L., Nielsen, S. R., Mcneilly, S., Prein, C., Rafaeva, M., Schoof, E. M., Furtwängler, B., Porse, B. T., Kim, H., Won, K. J., Sudhop, S., Zornhagen, K. W., Suhr, F. & 11 others, , 2021, In: Nature Materials. 20, p. 892–903Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy
Estruch Alrich, Montserrat, Reckzeh, K., Vittori, Camilla, Centio, A., Ali, M., Engelhard, Sophia Manon Charlotte, Zhao, L., Won, K. J., Liu, P., Porse, Bo Torben & Theilgaard-Mønch, Kim, 2021, In: Leukemia. 35, p. 2030-2042Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ASXL1-G643W variant accelerates the development of CEBPA mutant acute myeloid leukemia
D'Altri, T., Wilhelmson, Anna, Schuster, Mikkel Bruhn, Wenzel, Anne, Kalvisa, A., Pundhir, Sachin, Hansen, A. M. & Porse, Bo Torben, 2021, In: Haematologica. 106, 4, p. 1000-1007 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The eha research roadmap: normal hematopoiesis
Jaffredo, T., Balduini, A., Bigas, A., Bernardi, R., Bonnet, D., Canque, B., Charbord, P., Cumano, A., Delwel, R., Durand, C., Fibbe, W., Forrester, L., De Franceschi, L., Ghevaert, C., Gjertsen, B., Gottgens, B., Graf, T., Heidenreich, O., Hermine, O., Higgs, D. & 21 others, , 2021, In: HemaSphere. 5, 12, e669.Research output: Contribution to journal › Review › Research › peer-review
- 2020
- Published
CCAAT enhancer binding protein alpha (CEBPA) biallelic acute myeloid leukaemia: cooperating lesions, molecular mechanisms and clinical relevance
Wilhelmson, Anna & Porse, Bo Torben, 2020, In: British Journal of Haematology. 190, 4, p. 495-507Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4985646
Most downloads
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3481
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spliceR: an R package for classification of alternative splicing and prediction of coding potential from RNA-seq data
Research output: Contribution to journal › Journal article › Research › peer-review
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2748
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Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2479
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HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
Research output: Contribution to journal › Journal article › Research › peer-review
Published