Amelie Stein
Associate Professor
Computational and RNA Biology
Ole Maaløes Vej 5
2200 København N.
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Protein destabilization and degradation as a mechanism for hereditary disease
Nielsen, S. V., Schenstrøm, S. M., Christensen, Caspar Elo, Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2020, Protein Homeostasis Diseases: Mechanisms and Novel Therapies. Pey, A. L. (ed.). Elsevier, p. 111-125Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Protein stability and degradation in health and disease
Bjørnkjær, Lene, Abildgaard, A. B., Gersing, S. K., Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2019, Molecular Chaperones in Human Disorders. Donev, R. (ed.). Academic Press, p. 61-83 (Advances in Protein Chemistry and Structural Biology, Vol. 114).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Random mutagenesis analysis of the Influenza A M2 proton channel reveals novel resistance mutants
Santner, P., Martins, J. M. D. S., Kampmeyer, Caroline, Hartmann-Petersen, Rasmus, Laursen, J. S., Stein, Amelie, Olsen, Christian Adam, Arkin, I. T., Winther, Jakob R., Willemoës, Martin & Lindorff-Larsen, Kresten, 2018, In: Biochemistry. 57, 41, p. 5957-5968Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid protein stability prediction using deep learning representations
Blaabjerg, Lasse Møller, Kassem, M. M., Good, L. L., Jonsson, Nicolas, Cagiada, Matteo, Johansson, Kristoffer Enøe, Boomsma, Wouter, Stein, Amelie & Lindorff-Larsen, Kresten, 2023, In: eLife. 12, 19 p., e82593.Research output: Contribution to journal › Journal article › Research › peer-review
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Rare Catechol-O-methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets
Larsen, Fia Brunsgaard Valsted, Cagiada, Matteo, Dideriksen, J., Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2023, In: Biochemistry. 62, 8, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Toward mechanistic models for genotype-phenotype correlations in phenylketonuria using protein stability calculations
Scheller, R., Stein, Amelie, Nielsen, S. V., Marin, F. I., Gerdes, Anne-Marie Axø, Di Marco, M., Papaleo, E., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2019, In: Human Mutation. 40, 4, p. 444-457Research output: Contribution to journal › Journal article › Research › peer-review
Uncovering new substrates for Aurora A kinase
Sardon, T., Pache, R. A., Stein, Amelie, Molina, H., Vernos, I. & Aloy, P., 2010, In: EMBO Reports. 11, 12, p. 977-984 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Understanding the Origins of Loss of Protein Function by Analyzing the Effects of Thousands of Variants on Activity and Abundance
Cagiada, Matteo, Johansson, Kristoffer Enøe, Valanciute, A., Nielsen, S. V., Hartmann-Petersen, Rasmus, Yang, J. J., Fowler, D. M., Stein, Amelie & Lindorff-Larsen, Kresten, 2021, In: Molecular Biology and Evolution. 38, 8, p. 3235-3246Research output: Contribution to journal › Journal article › Research › peer-review
ID: 144764550
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293
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Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations
Research output: Contribution to journal › Journal article › Research › peer-review
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162
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Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome
Research output: Contribution to journal › Journal article › Research › peer-review
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97
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Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome
Research output: Contribution to journal › Review › Research › peer-review
Published