Anne Tybjærg-Hansen
Clinical Professor
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Promotor polymorphisms in leukotriene C4 synthase and risk of ischemic cerebrovascular disease.
Freiberg, J. J., Tybjærg-Hansen, Anne, Sillesen, Henrik, Jensen, G. B., Nordestgaard, Børge, Freiberg, J. J., Tybjærg-Hansen, Anne, Sillesen, H., Jensen, G. B. & Nordestgaard, B. G., 2008, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 5, p. 990-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome
Zanoni, P., Panteloglou, G., Othman, A., Haas, J. T., Meier, R., Rimbert, A., Futema, M., Khalil, Y. A., Norrelykke, S. F., Rzepiela, A. J., Stoma, S., Stebler, M., Van Dijk, F., Wijers, M., Wolters, J. C., Dalila, N., Huijkman, N. C. A., Smit, M., Gallo, A., Carreau, V. & 26 others, , 2022, In: Circulation Research. 130, 1, p. 80-95 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial Hypertriglyceridaemia Revisited in the Era of Non-fasting Lipid Profiles: Executive Summary of a 2019 Expert Panel Statement
Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, Anne, Tentolouris, N. & Nordestgaard, Børge, 2019, In: Current Vascular Pharmacology. 17, 5, p. 538-540Research output: Contribution to journal › Review › Research › peer-review
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Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Main Text
Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, Anne, Tentolouris, N. & Nordestgaard, Børge, 2019, In: Current Vascular Pharmacology. 17, 5, p. 498-514Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Narrative Review
Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, Anne, Tentolouris, N. & Nordestgaard, Børge, 2019, In: Current Vascular Pharmacology. 17, 5, p. 515-537Research output: Contribution to journal › Review › Research › peer-review
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Population-Based Resequencing of APOA1 in 10,330 Individuals: Spectrum of Genetic Variation, Phenotype, and Comparison with Extreme Phenotype Approach
Haase, C. L., Frikke-Schmidt, R., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2012, In: P L o S Genetics. 8, 11, p. e1003063Research output: Contribution to journal › Journal article › Research › peer-review
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Polymorphisms in apolipoprotein B and risk of ischemic stroke
Benn, M., Nordestgaard, Børge, Jensen, J. S. & Tybjærg-Hansen, Anne, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 9, p. 3611-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polymorphism in APOB associated with increased low-density lipoprotein levels in both genders in the general population
Benn, M., Nordestgaard, Børge, Jensen, J. S., Grande, P., Sillesen, H. & Tybjærg-Hansen, Anne, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 10, p. 5797-803 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polygenic risk scores: how much do they add?
Christoffersen, M. & Tybjærg-Hansen, Anne, 2021, In: Current Opinion in Lipidology. 32, 3, p. 157-162 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polygenic Risk Scores
Christoffersen, M. & Tybjærg-Hansen, Anne, 2022, Cardiovascular Risk Assessment in Primary Prevention. Humana Press, p. 429-446 (Contemporary Cardiology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Plasma levels of apolipoprotein E, APOE genotype, and all-cause and cause-specific mortality in 105949 individuals from a white general population cohort
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 1 Sep 2019, In: European Heart Journal. 40, 33, p. 2813-2824 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma levels of apolipoprotein E and risk of ischemic heart disease in the general population
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Mar 2016, In: Atherosclerosis. 246, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma levels of apolipoprotein E and risk of dementia in the general population
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Feb 2015, In: Annals of Neurology. 77, 2, p. 301-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma levels of 27-hydroxycholesterol in humans and mice with monogenic disturbances of high density lipoprotein metabolism
Karuna, R., Holleboom, A. G., Motazacker, M. M., Kuivenhoven, J. A., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Georgopoulos, S., van Eck, M., van Berkel, T. J. C., von Eckardstein, A. & Rentsch, K. M., 1 Feb 2011, In: Atherosclerosis. 214, 2, p. 448-55 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma high-density lipoprotein cholesterol and risk of dementia: observational and genetic studies
Kjeldsen, E. W., Thomassen, J. Q., Juul Rasmussen, I., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Cardiovascular Research. 118, 5, p. 1330-1343 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma apolipoprotein E levels and risk of dementia: A Mendelian randomization study of 106,562 individuals
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Jan 2018, In: Alzheimer's & Dementia. 14, 1, p. 71-80Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma YKL-40 and total and disease-specific mortality in the general population
Johansen, Julia Sidenius, Bojesen, Stig Egil, Tybjærg-Hansen, Anne, Mylin, A. K., Price, P. A. & Nordestgaard, Børge, 1 Oct 2010, In: Clinical Chemistry. 56, 10, p. 1580-91 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma TSH and cardiovascular disease in the general population: A Mendelian randomization study of 105,224 individuals
Dalila, N., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2023, In: Atherosclerosis. 376, p. 26-33 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
Voight, B. F., Peloso, G. M., Orho-Melander, M., Frikke-Schmidt, R., Barbalic, M., Jensen, M. K., Hindy, G., Hólm, H., Ding, E. L., Johnson, T., Schunkert, H., Samani, N. J., Clarke, R., Hopewell, J. C., Thompson, J. F., Li, M., Thorleifsson, G., Newton-Cheh, C., Musunuru, K., Pirruccello, J. P. & 106 others, , 2012, In: Lancet. 380, 9841, p. 572-80 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma Concentrations of Magnesium and Risk of Dementia: A General Population Study of 102 648 Individuals
Thomassen, J. Q., Tolstrup, J. S., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2021, In: Clinical Chemistry. 67, 6, p. 899-911 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma Concentrations of Calcium and Risk of Alzheimer Disease—Observational and Genetic Studies
Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: Clinical Chemistry. 69, 5, p. 525-536 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physical activity in leisure time and at work and risk of dementia: A prospective cohort study of 117,616 individuals
Juul Rasmussen, I., Rasmussen, Katrine Laura, Thomassen, J. Q., Nordestgaard, Børge, Schnohr, P., Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Atherosclerosis. 360, p. 53-60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Phenotype of heterozygotes for low-density lipoprotein receptor mutations identified in different background populations
Tybjærg-Hansen, Anne, Jensen, H. K., Benn, M., Steffensen, R., Jensen, G. & Nordestgaard, Børge, 2005, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 25, 1, p. 211-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacogenetics-guided CETP inhibition: an open question?
Tybjærg-Hansen, Anne, Nordestgaard, L. T. & Christoffersen, M., 2022, In: European Heart Journal. 43, 39, p. 3957-3959 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Pentanucleotide repeat polymorphism, lipoprotein(a) levels, and risk of ischemic heart disease
Kamstrup, P. R., Tybjærg-Hansen, Anne, Steffensen, R. & Nordestgaard, B. G., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 3769-3776 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Penetrance of NOD2/CARD15 genetic variants in the general population
Yazdanyar, S., Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 20 Apr 2010, In: C M A J. 182, 7, p. 661-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PCSK9 R46L, low-density lipoprotein cholesterol levels, and risk of ischemic heart disease: 3 independent studies and meta-analyses
Benn, Marianne, Nordestgaard, Børge, Grande, P., Schnohr, P., Tybjærg-Hansen, Anne & Benn, M., 22 Jun 2010, In: Journal of the American College of Cardiology. 55, 25, p. 2833-42 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PCSK9 R46L Loss-of-Function Mutation Reduces Lipoprotein(a), LDL Cholesterol, and Risk of Aortic Valve Stenosis
Langsted, A., Nordestgaard, Børge, Benn, Marianne, Tybjærg-Hansen, Anne & Kamstrup, P. R., Sep 2016, In: The Journal of clinical endocrinology and metabolism. 101, 9, p. 3281-3287 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
Vallejo-Vaz, A. J., Marco, M. D., Stevens, C. A. T., Akram, A., Freiberger, T., Hovingh, G. K., Kastelein, J. J. P., Mata, P., Raal, F. J., Santos, R. D., Soran, H., Watts, G. F., Abifadel, M., Aguilar Salinas, C. A., Al-Khnifsawi, M., Alkindi, F. A., Alnouri, F., Alonso, R., Al-Rasadi, K., Al-Sarraf, A. & 248 others, , 2018, In: Atherosclerosis. 277, p. 234-255 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Observational and genetic studies of C-reactive protein levels and risk of Alzheimer's disease
Frikke-Schmidt, Ruth, Hegazy, S. H., Rasmussen, I. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Thomassen, J. Q., 2022, In: Alzheimer's and Dementia. 18, 12, p. 2734-2735Research output: Contribution to journal › Comment/debate › Research › peer-review
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Obesity increases heart failure incidence and mortality: observational and Mendelian randomization studies totalling over 1 million individuals
Benn, Marianne, Marott, S. C. W., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2022, In: Cardiovascular Research. 118, 18, p. 3576-3585 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel mutations in leukotriene C4 synthase and risk of cardiovascular disease based on genotypes from 50,000 individuals
Freiberg, J. J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 Aug 2010, In: Journal of Thrombosis and Haemostasis. 8, 8, p. 1694-701 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel genes in LDL metabolism: a comprehensive overview
Christoffersen, M. & Tybjærg-Hansen, Anne, Jun 2015, In: Current Opinion in Lipidology. 26, 3, p. 179-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nose and blood pressure
Dahl, M., Tybjærg-Hansen, Anne, Nordestgaard, Børge, Lange, Peter & Vestbo, J., 15 Jan 2004, In: American Journal of Respiratory and Critical Care Medicine. 169, 2, p. 318; author reply 319Research output: Contribution to journal › Journal article › Research › peer-review
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Nonfasting triglycerides, cholesterol, and ischemic stroke in the general population
Varbo, A., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Schnohr, P., Jensen, G. B., Benn, M. & Benn, M., 1 Apr 2011, In: Annals of Neurology. 69, 4, p. 628-34 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
Nordestgaard, Børge, Benn, M., Schnohr, P. & Tybjærg-Hansen, Anne, 2007, In: J A M A: The Journal of the American Medical Association. 298, 3, p. 299-308 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonfasting glucose, ischemic heart disease, and myocardial infarction: a Mendelian randomization study
Benn, M., Tybjærg-Hansen, Anne, McCarthy, M. I., Jensen, G. B., Grande, P. & Nordestgaard, Børge, 2012, In: Journal of the American College of Cardiology. 59, 25, p. 2356-65 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonfasting cholesterol and triglycerides and association with risk of myocardial infarction and total mortality: the Copenhagen City Heart Study with 31 years of follow-up
Langsted, A., Freiberg, J. J., Tybjaerg-Hansen, A., Schnohr, P., Jensen, G. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 1 Jul 2011, In: Journal of Internal Medicine. 270, 1, p. 65-75 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonfasting Triglycerides remnant lipoproteins, and cardiovascular disease
Tybjærg-Hansen, Anne, Nordestgaard, B. G. & Nordestgaard, Børge, 2009, In: Klinisk Kemi i Norden. 21, 3, p. 10-16 7 p.Research output: Contribution to journal › Journal article › Research
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Nonfasting Triglycerides and Risk of Ischemic Stroke in the General Population
Freiberg, J. J., Tybjærg-Hansen, Anne, Jensen, J. S. & Nordestgaard, B. G., 2008, In: JAMA - Journal of the American Medical Association. 300, 18, p. 2142-2152 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nicotinic acetylcholine receptor polymorphism, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases: a cohort study
Kaur-Knudsen, D., Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2011, In: Journal of Clinical Oncology. 29, 21, p. 2875-82 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Neutrophil counts and cardiovascular disease
Luo, J., Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 47, p. 4953-4964 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans
Oldoni, F., van Capelleveen, J. C., Dalila, N., Wolters, J. C., Heeren, J., Sinke, R. J., Hui, D. Y., Dallinga-Thie, G. M., Frikke-Schmidt, Ruth, Hovingh, K. G., van de Sluis, B., Tybjærg-Hansen, Anne & Kuivenhoven, J. A., 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 7, p. 1440-1453 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutations in Danish patients with long QT syndrome and the identification of a large founder family with p.F29L in KCNH2
Christiansen, M., Hedley, P. L., Theilade, J., Stoevring, B., Leren, T. P., Eschen, O., Sørensen, K. M., Tybjærg-Hansen, Anne, Ousager, L. B., Pedersen, L. N., Frikke-Schmidt, Ruth, Aidt, F. H., Hansen, M. G., Hansen, J., Bloch Thomsen, P. E., Toft, E., Henriksen, F. L., Bundgård, Henning, Jensen, H. K. & Kanters, Jørgen K., 2014, In: BMC Medical Genetics. 15, 11 p., 31.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217
Benn, M., Watts, G. F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 May 2016, In: European Heart Journal. 37, 17, p. 1384-94 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutation in apolipoprotein B associated with hypobetalipoproteinemia despite decreased binding to the low density lipoprotein receptor
Benn, M., Nordestgaard, Børge, Jensen, J. S., Nilausen, K. S., Meinertz, H. & Tybjærg-Hansen, Anne, 2005, In: Journal of Biological Chemistry. 280, 22, p. 21052-60 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutation in APOA1 predicts increased risk of ischaemic heart disease and total mortality without low HDL cholesterol levels
Haase, C. L., Frikke-Schmidt, Ruth, Nordestgaard, Børge, Kateifides, A. K., Kardassis, D., Nielsen, L. B., Andersen, C. B., Køber, Lars Valeur, Johnsen, A. H., Grande, P., Zannis, V. I. & Tybjærg-Hansen, Anne, 2011, In: Journal of Internal Medicine. 270, 2, p. 136-46 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutation in APOA1 predicts increased risk of ischaemic heart disease and mortality without low HDL cholesterol
Haase, C. L., Frikke-Schmidt, Ruth, Nordestgaard, Børge, Kateifides, A. K., Kardassis, D., Nielsen, L. B., Johnsen, A. H., Grande, P., Zannis, V. I., Tybjaerg-Hansen, A., Johnsen, A. H. & Tybjærg-Hansen, Anne, 2010, In: Amyloid: the Journal of Protein Folding Disorders. 17, p. 129 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Mutation analysis and evaluation of the cardiac localization of TMEM43 in arrhythmogenic right ventricular cardiomyopathy
Christensen, Alex Hørby, Andersen, C. B., Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, Jesper Hastrup, 2011, In: Clinical Genetics. 80, 3, p. 256-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Morbiditet og mortalitet hos personer med mannosebindende lektinmangel. Osterbroundersøgelsen
Dahl, M., Tybjærg-Hansen, Anne, Schnohr, P. & Nordestgaard, Børge, 6 Dec 2004, In: Ugeskrift for Laeger. 166, 50, p. 4606-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular diagnosis of intermediate and severe α<inf>1</inf>-antitrypsin deficiency: MZ individuals with chronic obstructive pulmonary disease may have lower lung function than MM individuals
Dahl, Morten, Nordestgaard, Børge, Lange, Peter, Vestbo, J. & Tybjærg-Hansen, Anne, 2001, In: Clinical Chemistry.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular diagnosis of intermediate and severe alpha(1)-antitrypsin deficiency: MZ individuals with chronic obstructive pulmonary disease may have lower lung function than MM individuals
Dahl, M., Nordestgaard, Børge, Lange, Peter, Vestbo, J. & Tybjærg-Hansen, Anne, Jan 2001, In: Clinical Chemistry. 47, 1, p. 56-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Modifications to the Patient Rule-Induction Method that utilize non-additive combinations of genetic and environmental effects to define partitions that predict ischemic heart disease
Dyson, G., Frikke-Schmidt, Ruth, Nordestgaard, B. G., Tybjærg-Hansen, Anne & Sing, C. F., 2009, In: Genetic Epidemiology. 33, 4, p. 317-24 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mitochondrial haplogroups: ischemic cardiovascular disease, other diseases, mortality, and longevity in the general population
Benn, M., Schwartz, M., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2008, In: Circulation. 117, 19, p. 2492-501 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Missense variants in plakophilin-2 in arrhythmogenic right ventricular cardiomyopathy patients--disease-causing or innocent bystanders?
Christensen, Alex Hørby, Benn, Marianne, Tybjærg-Hansen, Anne, Haunso, S., Svendsen, Jesper Hastrup, Christensen, A. H., Benn, M., Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, Jesper Hastrup, 1 Jan 2010, In: Cardiology. 115, 2, p. 148-54 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Missense variants in plakophilin-2 in arrhythmogenic right ventricular cardiomyopathy patients - disease - causing or innocent bystanders?
Christensen, A. H., Benn, Marianne, Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, J. H., 2009, In: Cardiology. 115, 2, p. 148-154 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Missense polymorphisms in BRCA1 and BRCA2 and risk of breast and ovarian cancer
Dombernowsky, S. L., Weischer, M., Freiberg, J. J., Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2009, In: Cancer Epidemiology, Biomarkers & Prevention. 18, 8, p. 2339-42 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses
Gaziano, L., Sun, L., Arnold, M., Bell, S., Cho, K., Kaptoge, S. K., Song, R. J., Burgess, S., Posner, D. C., Mosconi, K., Robinson-Cohen, C., Mason, A. M., Bolton, T. R., Tao, R., Allara, E., Schubert, P., Chen, L., Staley, J. R., Staplin, N., Altay, S. & 30 others, , 2022, In: Circulation. 146, 20, p. 1507-1517 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Methylenetetrahydrofolate reductase polymorphism (C677T), hyperhomocysteinemia, and risk of ischemic cardiovascular disease and venous thromboembolism: prospective and case-control studies from the Copenhagen City Heart Study
Frederiksen, J., Juul, K., Grande, P., Jensen, G. B., Schroeder, T. V., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 15 Nov 2004, In: Blood. 104, 10, p. 3046-51 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mendelsk randomisering - eller hvordan man kan bruge gener til at sandsynliggøre kausalitet.
Tybjærg-Hansen, Anne, May 2010, In: DSKB-Nyt. 2, p. 18-21 4 p.Research output: Contribution to journal › Journal article › Research
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Medullary thyroid cancer: RET testing of an archival material
Godballe, C., Jørgensen, G., Gerdes, Anne-Marie Axø, Krogdahl, A. S., Tybjærg-Hansen, Anne & Nielsen, Finn Cilius, 1 Apr 2010, In: European Archives of Oto-Rhino-Laryngology. 267, 4, p. 613-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Measures to assess the prognostic ability of the stratified Cox proportional hazards model
(Tybjaerg-Hansen, A. ). T. F. S. C. T. C. C. H. S. & Tybjærg-Hansen, Anne, 2009, In: Statistics in Medicine. 28, 3, p. 389-411 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Major lipids, apolipoproteins and risk of vascular disease.
(Tybjaerg-Hansen, A. ). T. E. R. F. C. T. C. C. H. S. & Tybjærg-Hansen, Anne, 2009, In: JAMA - Journal of the American Medical Association. 302, p. 1993-2000 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Macular Degeneration and CETP Inhibition-Reply
Nordestgaard, L. T., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2022, In: JAMA Cardiology. 7, 7, p. 775-776 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Low-density lipoprotein cholesterol and the risk of cancer: a mendelian randomization study
Benn, Marianne, Tybjærg-Hansen, Anne, Stender, Stefan, Frikke-Schmidt, Ruth, Nordestgaard, Børge & Benn, M., 16 Mar 2011, In: National Cancer Institute. Journal (Print). 103, 6, p. 508-19 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Low-density lipoprotein cholesterol and risk of gallstone disease: A Mendelian randomization study and meta-analyses
Stender, S., Frikke-Schmidt, R., Benn, M., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2013, In: Journal of Hepatology. 58, 1, p. 126-33 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Low and high pancreatic amylase is associated with pancreatic cancer and chronic pancreatitis
Hansen, S. E. J., Langsted, A., Varbo, A., Madsen, C. M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, In: European Journal of Epidemiology. 36, p. 975–984Research output: Contribution to journal › Journal article › Research › peer-review
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Low Nonfasting Triglycerides and Reduced All-Cause Mortality: A Mendelian Randomization Study
Thomsen, M., Varbo, A., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2014, In: Clinical Chemistry. 60, 5, p. 737-746 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Low LDL cholesterol, PCSK9 and HMGCR genetic variation, and risk of Alzheimer's disease and Parkinson's disease: Mendelian randomisation study
Benn, Marianne, Nordestgaard, Børge, Frikke-Schmidt, Ruth & Tybjærg-Hansen, Anne, 24 Apr 2017, In: B M J. 357, 11 p., j1648.Research output: Contribution to journal › Journal article › Research › peer-review
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Low LDL Cholesterol by PCSK9 Variation Reduces Cardiovascular Mortality
Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Jun 2019, In: Journal of the American College of Cardiology. 73, 24, p. 3102-3114Research output: Contribution to journal › Journal article › Research › peer-review
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Loss-of-function mutation in ABCA1 and risk of Alzheimer's disease and cerebrovascular disease
Nordestgaard, L. T., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Dec 2015, In: Alzheimer's & Dementia. 11, 12, p. 1430-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease
Jørgensen, A. B., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, Jul 2014, In: New England Journal of Medicine. 371, 1, p. 32-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Long-term Benefits and Harms Associated with Genetic Cholesteryl Ester Transfer Protein Deficiency in the General Population
Nordestgaard, L. T., Christoffersen, M., Lauridsen, B. K., Afzal, Shoaib, Nordestgaard, Børge, Frikke-Schmidt, Ruth & Tybjærg-Hansen, Anne, 2022, In: JAMA Cardiology. 7, 1, p. 55-64Research output: Contribution to journal › Journal article › Research › peer-review
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Liver fat content, non-alcoholic fatty liver disease, and ischaemic heart disease: Mendelian randomization and meta-analysis of 279 013 individuals
Lauridsen, B. K., Stender, Steen, zwp671, zwp671, Kofoed, Klaus Fuglsang, Køber, Lars Valeur, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 5, p. 385-393 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality
(Tybjaerg-Hansen, A. ). T. F. S. C. T. C. C. H. S. & Tybjærg-Hansen, Anne, 2009, In: JAMA - Journal of the American Medical Association. 302, 4, p. 412-423 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipoprotein(a) as a cardiovascular risk factor: current status
Nordestgaard, Børge, Chapman, M. J., Ray, K., Borén, J., Andreotti, F., Watts, G. F., Ginsberg, H., Amarenco, P., Catapano, A., Descamps, O. S., Fisher, E., Kovanen, P. T., Kuivenhoven, J. A., Lesnik, P., Masana, L., Reiner, Z., Taskinen, M., Tokgözoglu, L., Tybjærg-Hansen, Anne & European Atherosclerosis Society Consensus Panel, E. A. S. C. P., 1 Dec 2010, In: European Heart Journal. 31, 23, p. 2844-53 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipoprotein(a) and risk of myocardial infarction--genetic epidemiologic evidence of causality
Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 2, p. 87-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipoprotein(a) and familial hypercholesterolaemia - Authors' reply
Langsted, A., Kamstrup, P. R., Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Sep 2016, In: The Lancet Diabetes and Endocrinology. 4, 9, p. 730-731 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Lipoprotein(a) Levels at Birth and in Early Childhood: The COMPARE Study
Strandkjær, N., Hansen, M. K., Nielsen, S. T., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Nordestgaard, Børge, Tabor, Ann, Bundgård, Henning, Iversen, Kasper & Kamstrup, P. R., 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 2, p. 324-335 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipoprotein distribution and serum concentrations of 7α-hydroxy-4-cholesten-3-one and bile acids: effects of monogenic disturbances in high-density lipoprotein metabolism
Steiner, C., Holleboom, A. G., Karuna, R., Motazacker, M. M., Kuivenhoven, J. A., Frikke-Schmidt, R., Tybjærg-Hansen, Anne, Rohrer, L., Rentsch, K. M. & von Eckardstein, A., 2012, In: Clinical Science. 122, 8, p. 385-96 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipoprotein Subclass Profiling Reveals Pleiotropy in the Genetic Variants of Lipid Risk Factors for Coronary Heart Disease: A Note on Mendelian Randomization Studies
Würtz, P., Kangas, A. J., Soininen, P., Lehtimäki, T., Kähönen, M., Viikari, J. S., Raitakari, O. T., Järvelin, M., Davey Smith, G., Ala-Korpela, M., Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2013, In: Journal of the American College of Cardiology. 62, 20, p. 1906-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipid-related markers and cardiovascular disease prediction
Di Angelantonio, E., Gao, P., Pennells, L., Kaptoge, S., Caslake, M., Thompson, A., Butterworth, A. S., Sarwar, N., Wormser, D., Saleheen, D., Ballantyne, C. M., Psaty, B. M., Sundström, J., Ridker, P. M., Nagel, D., Gillum, R. F., Ford, I., Ducimetiere, P., Kiechl, S., Koenig, W. & 31 others, , 2012, In: J A M A: The Journal of the American Medical Association. 307, 23, p. 2499-506 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leukotriene C4 synthase and ischemic cardiovascular disease and obstructive pulmonary disease in 13,000 individuals
Freiberg, J. J., Dahl, M., Tybjærg-Hansen, Anne, Grande, P. & Nordestgaard, B. G., 2009, In: Journal of Molecular and Cellular Cardiology. 46, 4, p. 579-86 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leukotriene C-4 synthase and ischemic cardiovascular disease and obstructive pulmonary disease in 13,000 individuals
Freiberg, J. J., Dahl, Morten, Tybjærg-Hansen, Anne, Grande, P. & Nordestgaard, B. G., Apr 2009, In: Journal of Molecular and Cellular Cardiology. 46, 4, p. 579-586Research output: Contribution to journal › Journal article › Research › peer-review
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Late-breaking abstract: Glutathione-S-transferase P1 Ile105Val polymorphism associated with elevated lung function and reduced risk of lung cancer and death in 66,000 individuals
Dahl, Morten, Norskov, M., Nordestgaard, B. & Tybjærg-Hansen, Anne, Sep 2014.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
LCAT, HDL Cholesterol and Ischemic Cardiovascular Disease: A Mendelian Randomization Study of HDL Cholesterol in 54,500 Individuals
Haase, C. L., Tybjærg-Hansen, Anne, Ali Qayyum, A., Schou, J., Nordestgaard, Børge & Frikke-Schmidt, R., Feb 2012, In: Journal of Clinical Endocrinology and Metabolism. p. E248-56 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies
Sarwar, N., Butterworth, A. S., Freitag, D. F., Gregson, J., Willeit, P., Gorman, D. N., Gao, P., Saleheen, D., Rendon, A., Nelson, C. P., Braund, P. S., Hall, A. S., Chasman, D. I., Tybjærg-Hansen, A., Chambers, J. C., Benjamin, E. J., Franks, P. W., Clarke, R., Wilde, A. A. M., Trip, M. D. & 31 others, , 31 Mar 2012, In: Lancet. 379, 9822, p. 1205-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis
Ghouse, J., Sveinbjörnsson, G., Vujkovic, M., Seidelin, A-S., Gellert-Kristensen, H., Ahlberg, G., Tragante, V., Rand, S. A., Brancale, J., Vilarinho, S., Lundegaard, P. R., Sørensen, E., Erikstrup, C., Bruun, M. T., Jensen, B. A., Brunak, S., Banasik, K., Ullum, H., Verweij, N., Lotta, L. & 31 others, , 2024, In: Nature Genetics. 56, p. 827–837 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis
Trinder, M., Wang, Y., Madsen, C. M., Ponomarev, T., Bohunek, L., Daisley, B. A., Kong, H. J., Blauw, L. L., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Wurfel, M. M., Russell, J. A., Walley, K. R., Rensen, P. C. N., Boyd, J. H. & Brunham, L. R., 2021, In: Circulation. 143, 9, p. 921–934Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of the factor V Leiden mutation on infectious disease susceptibility and outcome: a population-based study
Benfield, Thomas, Dahl, M., Nordestgaard, B. G., Tybjærg-Hansen, Anne & Dahl, M., 15 Nov 2005, In: Journal of Infectious Diseases. 192, 10, p. 1851-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Factor V Leiden on susceptibility to and outcome from critical illness: a genetic association study
Benfield, T., Ejrnæs, K., Juul, K., Ostergaard, C., Helweg-Larsen, J., Weis, N., Munthe-Fog, L., Kronborg, G., Andersen, M. R., Tybjærg-Hansen, A., Nordestgaard, B. G., Garred, P., Benfield, T., Ejrnaes, K., Juul, K., Andersen, C. Ø., Helweg-Larsen, J., Weis, N. M., Munthe-Fog, L., Kronborg, G. & 4 others, , 1 Jan 2010, In: Critical Care (Online Edition). 14, 2, p. R28Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased Baseline C-Reactive Protein Concentrations Are Associated with Increased Risk of Infections: Results from 2 Large Danish Population Cohorts
Zacho, J., Benfield, Thomas, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Feb 2016, In: Clinical Chemistry. 62, 2, p. 335-42 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving prediction of ischemic cardiovascular disease in the general population using apolipoprotein B: the Copenhagen City Heart Study
Benn, M., Nordestgaard, B., Jensen, G. B., Tybjaerg-Hansen, A., Tybjærg-Hansen, Anne, Benn, M. & Nordestgaard, Børge, 2007, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 27, 3, p. 661-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel
Huang, J., Howie, B., Mccarthy, S., Memari, Y., Walter, K., Min, J. L., Danecek, P., Malerba, G., Trabetti, E., Zheng, H., Al Turki, S., Amuzu, A., Anderson, C. A., Anney, R., Antony, D., Artigas, M. S., Ayub, M., Bala, S., Barrett, J. C., Barroso, I. & 219 others, , 2015, In: Nature Communications. 6, 9 p., 8111.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of high glucose levels and glucose lowering on risk of ischaemic stroke: a Mendelian randomisation study and meta-analysis
Benn, Marianne, Emanuelsson, F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, In: Diabetologia. 64, p. 1492–1503Research output: Contribution to journal › Journal article › Research › peer-review
- Published
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Impact of diet on ten-year absolute cardiovascular risk in a prospective cohort of 94 321 individuals: A tool for implementation of healthy diets
Kjeldsen, E. W., Thomassen, J. Q., Rasmussen, Katrine Laura, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: The Lancet Regional Health - Europe. 19, 100419.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of cardiovascular risk factors and genetics on 10-year absolute risk of dementia: risk charts for targeted prevention
Juul Rasmussen, I., Rasmussen, K. L., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2020, In: European Heart Journal. 41, 41, p. 4024-4033 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of LDL Cholesterol on Microvascular Versus Macrovascular Disease: A Mendelian Randomization Study
Emanuelsson, F., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, Sep 2019, In: Journal of the American College of Cardiology. 74, 11, p. 1465-1476Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of Glucose Level on Micro- and Macrovascular Disease in the General Population: A Mendelian Randomization Study
Emanuelsson, F., Marott, S., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Benn, Marianne, Apr 2020, In: Diabetes Care. 43, 4, p. 894-902 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 924951
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ABCA7 and risk of dementia and vascular disease in the Danish population
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The UK10K project identifies rare variants in health and disease
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Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
Research output: Contribution to journal › Journal article › Research › peer-review
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