Leila Lo Leggio
Professor
Department of Chemistry
Universitetsparken 5
2100 København Ø
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Xylanase-oligosaccharide interactions studied by a competitive enzyme assay
Lo Leggio, Leila & Pickersgill, R. W., 1999, In: Enzyme and Microbial Technology. 25, p. 701-709Research output: Contribution to journal › Journal article › Research › peer-review
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X-Ray Crystallographic Study of Xylopentaose Binding to Pseudomonas fluorescens Xylanase A.
Lo Leggio, Leila, Jenkins, J., Harris, G. W. & Pickersgill, R. W., 2000, In: Proteins - Structure Function and Bioinformatics. 41, p. 362-373Research output: Contribution to journal › Journal article › Research › peer-review
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Unliganded and substrate bound structures of the cellooligosaccharide active lytic polysaccharide monooxygenase LsAA9A at low pH
Frandsen, Kristian Erik Høpfner, Poulsen, Jens-Christian Navarro, Tandrup, T. & Lo Leggio, Leila, 2017, In: Carbohydrate Research. 448, p. 187-190 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases
Frandsen, K. E. H., Simmons, T. J., Dupree, P., Poulsen, J-C. N., Hemsworth, G. R., Ciano, L., Johnston, E. M., Tovborg, M., Johansen, K. S., von Freiesleben, P., Marmuse, L., Fort, S., Cottaz, S., Driguez, H., Henrissat, B., Lenfant, N., Tuna, F., Baldansuren, A., Davies, G. J., Lo Leggio, L. & 1 others, , 2016, In: Nature Chemical Biology. 12, 4, p. 298-303 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Structure of Endo-ß-1,4-galactanase from Bacillius licheniformis in Complex with Two Oligosaccharide Products
Ryttersgaard, C., Le Nours, J., Lo Leggio, Leila, Thea Jørgensen, C., Lehmann Hylling Christensen, L., Bjørnvad, M. & Larsen, Sine, 2004, In: Journal of Molecular Biology. 341, p. 107-117Research output: Contribution to journal › Journal article › Research › peer-review
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The Structure and Specificity of Escherichia coli Maltose Acetyltransferase Give New Insight into the LacA Family of Acyltransferases
Lo Leggio, Leila, Dal Degan, F., Poulsen, P., Møller Andersen, S. & Larsen, Sine, 2003, In: Biochemistry. 42, p. 5225-5235Research output: Contribution to journal › Journal article › Research › peer-review
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The Structure and Characterization of a Modular Endo-ß-1,4-mannanase from Cellulomonas fimi
Le Nours, J., Anderson, L., Stoll, D., Stålbrand, H. & Lo Leggio, Leila, 2005, In: Biochemistry. 44, p. 12700-12708Research output: Contribution to journal › Journal article › Research › peer-review
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The 1.62 Å structure of Thermoascus aurantiacus endoglucanase: completing the structural picture of subfamilies in glycoside hydrolase family 5
Lo Leggio, Leila & Larsen, Sine, 2002, In: FEBS Letters. 523, p. 103-108Research output: Contribution to journal › Journal article › Research › peer-review
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Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016)
Kryshtafovych, A., Albrecht, R., Basle, A., Bule, P., Caputo, A. T., Carvalho, A. L., Chao, K. L., Diskin, R., Fidelis, K., Fontes, C. M. G. A., Fredslund, F., Gilbert, H. J., Goulding, C. W., Hartmann, M. D., Hayes, C. S., Herzberg, O., Hill, J. C., Joachimiak, A., Kohring, G-W., Koning, R. I. & 19 others, , 2018, In: Proteins: Structure, Function, and Bioinformatics. 86, S1, p. 27-50 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Substrate specificity and subsite mobility in T. aurantiacus xylanase 10A
Lo Leggio, Leila, Kalogiannis, S., Eckert, K., Teixeira, S. C. M., Mahalingeswara, K. B., Andrei, C., Pickersgill, R. W. & Larsen, Sine, 2001, In: FEBS Letters. 509, p. 303-308Research output: Contribution to journal › Journal article › Research › peer-review
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Substrate preference of an ABC importer corresponds to selective growth on β-(1,6)-galactosides in Bifidobacterium animalis subsp. lactis
Theilmann, M. C., Fredslund, F., Svensson, B., Lo Leggio, Leila & Abou Hachem, M., 2019, In: Journal of Biological Chemistry. 294, 31, p. 11701-11711 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure–function analyses reveal that a glucuronoyl esterase from Teredinibacter turnerae interacts with carbohydrates and aromatic compounds
Arnling Bååth, J., Mazurkewich, S., Poulsen, Jens-Christian Navarro, Olsson, L., Lo Leggio, Leila & Larsbrink, J., 2019, In: Journal of Biological Chemistry. 294, 16, p. 6635-6644 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structures of two fungal ß-galactanases: Searching for the basis for temperature and pH optimum
Le Nours, J., Ryttersgaard, C., Lo Leggio, Leila, Østergaard, P. R., Vedel Borchert, T., Lehmann Hylling Christensen, L. & Larsen, Sine, 2003, In: Protein Science. 12, p. 1195-1204Research output: Contribution to journal › Journal article › Research › peer-review
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Structure-based engineering of glucose specificity in a family 10 xylanase from Streptomyces olivaceoviridis E-86
Ichinose, H., Diertavitian, S. W. S., Fujimoto, Z., Kuno, A., Lo Leggio, Leila & Kaneko, S., 2012, In: Process Biochemistry. 47, 3, p. 358-365 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure, function, and protein engineering of GH53 β-1,4-galactanases
Muderspach, Sebastian Jannick, Jensen, K., Krogh, K. B. R. M. & Lo Leggio, Leila, 2023, Glycoside Hydrolases: Biochemistry, Biophysics, and Biotechnology. Elsevier, p. 295-322 28 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors
Ernst, H. A., Olsen, A. N., Skriver, Karen, Larsen, Sine & Lo Leggio, Leila, 2004, In: EMBO Reports. 5, p. 297-303Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of the Sulfolobus solfataricus alpha-glucosidase: Implications for domain conservation and substrate recognition in GH31
Ernst, H. A., Lo Leggio, Leila, Willemoës, Martin, Leonard, G. A., Blum, P. & Larsen, Sine, 2006, In: Journal of Molecular Biology. 358, 4, p. 1106-24Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of dimeric, recombinant Sulfolobus solfataricus phosphoribosyl diphosphate synthase: a bent dimer defining the adenine specificity of the substrate ATP
Andersen, R. W., Lo Leggio, Leila, Hove-Jensen, B. & Kadziola, Anders, 2015, In: Extremophiles. 19, 2, p. 407-415 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of a lytic polysaccharide monooxygenase from Aspergillus fumigatus and an engineered thermostable variant
Lo Leggio, Leila, Weihe, C. D., Poulsen, Jens-Christian Navarro, Sweeney, M., Rasmussen, F., Lin, J., De Maria, L. & Wogulis, M., 2018, In: Carbohydrate Research. 469, p. 55-59 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of a hyperthermostable carbonic anhydrase identified from an active hydrothermal vent chimney
Fredslund, F., Borchert, M. S., Poulsen, Jens-Christian Navarro, Mortensen, S. B., Perner, M., Streit, W. R. & Lo Leggio, Leila, 2018, In: Enzyme and Microbial Technology. 114, p. 48-54 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of a fungal dimeric a-type carbonic anhydrase
Cuesta Seijo, J. A., Borchert, M. S., Poulsen, Jens-Christian Navarro, Schnorr, K. M., Mortensen, S. B. & Lo Leggio, Leila, 2011, In: F E B S Letters. 585, p. 1042-1048Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of Aspergillus aculeatus β-1,4-galactanase in complex with galactobiose
Torpenholt, S., Poulsen, Jens-Christian Navarro, Muderspach, Sebastian Jannick, De Maria, L. & Lo Leggio, Leila, 2019, In: Acta Crystallographica Section F: Structural Biology Communications. 75, 6, p. 399-404 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure and specificity of polysaccharidases belonging to clan GH-A
Lo Leggio, Leila, Le Nours, J., Ryttersgaard, C., Kaneko, S., Fujimoto, Z., Kuno, A., Diertavitian, S. & Larsen, Sine, 2004, Biotechnology of Lignocellulose Degradation and Biomass Utilization. Ohmiya, K., Sakka, K., Karita, S., Kimura, T., Sakka, M. & Onishi, Y. (eds.). UNI Publishers Co., Ltd, p. 27-33Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
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Structure and function of enzymes in biomass degradation
Welner, D. H., Jensen, M. H., McFarland, K. C., Poulsen, Jens-Christian Navarro, Otten, H., Salbo, R., Christensen, U., Harris, P., Larsen, Sine, Borchert, T., Christensen, L. L. H., Friis, E. P. & Lo Leggio, Leila, 2008, Biotechnology of lignocellulose degradation and Biomass Utilization - Mie Bioforum 2008. p. 349-355Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
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Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase
Lo Leggio, Leila, Simmons, T. J., Poulsen, Jens-Christian Navarro, Frandsen, Kristian Erik Høpfner, Hemsworth, G. R., Stringer, M. A., von Freiesleben, P., Tovborg, M., Johansen, K. S., De Maria, L., Harris, P. V., Soong, C., Dupree, P., Tryfona, T., Lenfant, N., Henrissat, B., Davies, G. J. & Walton, P. H., 2015, In: Nature Communications. 6, 9 p., 5961.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13810
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Purification, crystal structure determination and functional characterization of type III antifreeze proteins from the European eelpout Zoarces viviparus
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A structural overview of GH61proteins – fungal cellulose degrading polysaccharide monooxygenases
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Learning from oligosaccharide soaks of crystals of an AA13 lytic polysaccharide monooxygenase: crystal packing, ligand binding and active-site disorder
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