Agnete Kirkeby
Guest Researcher, Associate professor, group leader, Associate Professor
Developmental Neuroscience
Blegdamsvej 3B
2200 København N
Kirkeby Lab
Blegdamsvej 3
2200 København N
Member of:
- Published
Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors
Sachdeva, R., Jönsson, M. E., Nelander, J., Kirkeby, Agnete, Guibentif, C., Gentner, B., Naldini, L., Björklund, A., Parmar, M. & Jakobsson, J., 22 Jun 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 25, p. 11602-11607 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Therapeutic window for nonerythropoietic carbamylated-erythropoietin to improve motor function following multiple infarct ischemic strokes in New Zealand white rabbits
Lapchak, P. A., Kirkeby, Agnete, Zivin, J. A. & Sager, T. N., 31 Oct 2008, In: Brain Research. 1238, p. 208-214 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The stem cell niche finds its true north
Kirkeby, Agnete, Perlmann, T. & Pereira, C. F., 15 Aug 2016, In: Development (Cambridge). 143, 16, p. 2877-2881 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy
Leist, M., Bremer, S., Brundin, P., Hescheler, J., Kirkeby, Agnete, Krause, K. H., Pörzgen, P., Pucéat, M., Schmidt, M., Schrattenholz, A., Zak, N. B. & Hentze, H., 1 Dec 2008, In: Altex. 25, 3, p. 163-190 28 p.Research output: Contribution to journal › Review › Research › peer-review
Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications.
Moraghebi, R., Kirkeby, Agnete, Chaves, P., Roenn, R. E., Sitnicka, E., Parmar, M., Larsson, M., Herbst, A. & Woods, N., 25 Aug 2017, In: Stem Cell Research & Therapy. 8, 12 p., 190.Research output: Contribution to journal › Journal article › Research › peer-review
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Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats
Cardoso, T., Adler, A. F., Mattsson, B., Hoban, D. B., Nolbrant, S., Wahlestedt, J. N., Kirkeby, Agnete, Grealish, S., Björklund, A. & Parmar, M., 1 Sep 2018, In: The Journal of Comparative Neurology. 526, 13, p. 2133-2146Research output: Contribution to journal › Journal article › Research › peer-review
Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD)
Kirkeby, Agnete, Parmar, M. & Barker, R. A., 2017, Functional Neural Transplantation IV: Translation to Clinical Application, Part A. Vol. 230. p. 165-190 26 p. (Progress in Brain Research).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia
Garza, R., Sharma, Y., Atacho, D. A. M., Thiruvalluvan, Arun, Abu Hamdeh, S., Jönsson, M. E., Horvath, V., Adami, A., Ingelsson, M., Jern, P., Hammell, M. G., Englund, E., Kirkeby, Agnete, Jakobsson, J. & Marklund, N., 2023, In: Cell Reports. 42, 11, 19 p., 113395.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.
Kee, N., Volakakis, N., Kirkeby, Agnete, Dahl, L., Storvall, H., Nolbrant, S., Lahti, L., Bjoerklund, A. K., Gillberg, L., Joodmardi, E., Sandberg, R., Parmar, M. & Perlmann, T., 5 Jan 2017, In: Cell Stem Cell. 20, 1, p. 29-40 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
Tiklová, K., Nolbrant, S., Fiorenzano, A., Björklund, Å. K., Sharma, Y., Heuer, A., Gillberg, L., Hoban, D. B., Cardoso, T., Adler, A. F., Birtele, M., Lundén-Miguel, H., Volakakis, N., Kirkeby, Agnete, Perlmann, T. & Parmar, M., 1 Dec 2020, In: Nature Communications. 11, 1, 11 p., 2434.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis
Mondal, T., Juvvuna, P. K., Kirkeby, A., Mitra, S., Kosalai, S. T., Traxler, L., Hertwig, F., Wernig-Zorc, S., Miranda, C., Deland, L., Volland, R., Bartenhagen, C., Bartsch, D., Bandaru, S., Engesser, A., Subhash, S., Martinsson, T., Carén, H., Akyürek, L. M., Kurian, L. & 5 others, , 12 Mar 2018, In: Cancer Cell. 33, 3, p. 417-434.e7Research output: Contribution to journal › Journal article › Research › peer-review
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Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions
Häfner, Sophia Julia, Jansson, Martin David, Altinel, Kübra, Andersen, Kasper Langebjerg, Abay-Nørgaard, Zehra Caldwell, Ménard, Patrice, Fontenas, M., Sørensen, Daniel Madriz, Gay, David Michael, Arendrup, Frederic Schrøder, Tehler, D., Krogh, Nicolai, Nielsen, Henrik, Kraushar, M. L., Kirkeby, Agnete & Lund, Anders H., 2023, In: Developmental Cell. 58, 17, p. 1593-1609.e9Research output: Contribution to journal › Journal article › Research › peer-review
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Report of the international conference on manufacturing and testing of pluripotent stem cells
Abbot, S., Agbanyo, F., Ahlfors, J-E., Baghbaderani, B. A., Bartido, S., Bharti, K., Burke, C., Carlsson, B., Cavagnaro, J., Creasey, A., Lin, S., DiGiusto, D., Francissen, K., Gaffney, A., Goldring, C., Gorba, T., Griffiths, E., Lubiniecki, A., Vandeputte, J., Hanatani, T. & 23 others, , Nov 2018, In: Biologicals. 63, p. 67-83Research output: Contribution to journal › Conference article › Research › peer-review
Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease.
Kirkeby, Agnete, Nolbrant, S., Tiklova, K., Heuer, A., Kee, N., Cardoso, T., Ottosson, D. R., Lelos, M. J., Rifes, P., Dunnett, S. B., Grealish, S., Perlmann, T. & Parmar, M., 2017, In: Cell Stem Cell. 20, 1, p. 135-148 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD
Parmar, M., Novo Nordisk Cell Therapy R&D, N. N. C. T. R. & Christiansen, Josefine Rågård, 2023, In: Cell Stem Cell. 30, 10, p. 1299-1314.e9 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preclinical assessment of a pluripotent cell therapy for treatment of Parkinson's Disease
Kirkeby, Agnete, 2021, In: Toxicology Letters. 350, Supplement, p. S37 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Parkinson disease and growth factors — is GDNF good enough?
Kirkeby, Agnete & Barker, R. A., 1 Jun 2019, In: Nature Reviews Neurology. 15, 6, p. 312-314 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons
Grealish, S., Heuer, A., Cardoso, T., Kirkeby, Agnete, Jönsson, M., Johansson, J., Björklund, A., Jakobsson, J. & Parmar, M., 9 Jun 2015, In: Stem Cell Reports. 4, 6, p. 975-983 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient
Rifes, P., Isaksson, M., Rathore, Gaurav Singh, Aldrin-Kirk, P., Moller, O. K., Barzaghi, G., Lee, J., Egerod, Kristoffer Lihme, Belmont-Rausch, Dylan Matthew, Parmar, M., Pers, Tune H, Laurell, T. & Kirkeby, Agnete, 2020, In: Nature Biotechnology. 38, p. 1265-1273 9 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
MSLibrarian: Optimized Predicted Spectral Libraries for Data-Independent Acquisition Proteomics
Isaksson, M., Karlsson, C., Laurell, T., Kirkeby, Agnete & Heusel, M., 2022, In: Journal of Proteome Research. 21, 2, p. 535–546 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identifying secreted biomarkers of dopaminergic ventral midbrain progenitor cells
Rifes, P., Isaksson, M., Rusimbi, Charlotte Nuru, Ramón Santonja, A., Nelander, J., Laurell, T. & Kirkeby, Agnete, 2023, In: Stem Cell Research and Therapy. 14, 1, 354.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells.
Lehnen, D., Barral, S., Cardoso, T., Grealish, S., Heuer, A., Smiyakin, A., Kirkeby, Agnete, Kollet, J., Cremer, H., Parmar, M., Bosio, A. & Knoebel, S., Oct 2017, In: Stem Cell Reports. 9, 4, p. 1207-1220 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Embryonic Stem Cell-Derived Dopaminergic Grafts Alleviate L-DOPA Induced Dyskinesia
Elabi, O. F., Pass, R., Sormonta, I., Nolbrant, S., Drummond, N., Kirkeby, Agnete, Kunath, T., Parmar, M. & Lane, E. L., 2022, In: Journal of Parkinson's Disease. 12, 6, p. 1881-1896 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease
Grealish, S., Diguet, E., Kirkeby, Agnete, Mattsson, B., Heuer, A., Bramoulle, Y., Van Camp, N., Perrier, A. L., Hantraye, P., Björklund, A. & Parmar, M., 1 Jan 2014, In: Cell Stem Cell. 15, 5, p. 653-665 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO).
Kirkeby, Agnete, Torup, L., Bochsen, L., Kjalke, M., Abel, K., Theilgaard-Mønch, Kim, Johansson, P. I., Bjørn, S. E., Gerwien, J. & Leist, M., 2008, In: Thrombosis and Haemostasis. 99, 4, p. 720-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 172979835
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IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells.
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
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Bringing Advanced Therapies for Parkinson's Disease to the Clinic: The Scientist's Perspective
Research output: Contribution to journal › Review › Research › peer-review
Published -
39
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Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
Research output: Contribution to journal › Journal article › Research › peer-review
Published