Søren-Peter Olesen

Søren-Peter Olesen

Professor


Publication year:
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51 - 100 out of 153Page size: 50
  1. 2011
  2. Published

    Comparison of the Effects of a Transient Outward Potassium Channel Activator on Currents Recorded from Atrial and Ventricular Cardiomyocytes.

    Callø, Kirstine, Nof, E., Jespersen, Thomas, Di Diego, J. M., Chlus, N., Olesen, Søren-Peter, Antzelevitch, C. & Cordeiro, J. M., 2011, In: Journal of Cardiovascular Electrophysiology. 22, 9, p. 1057-1066 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Extracellular potassium inhibits Kv7.1 potassium channels by stabilizing an inactivated state

    Larsen, A. P., Steffensen, Annette Buur, Grunnet, Morten & Olesen, Søren-Peter, 2011, In: Biophysical Journal. 101, 4, p. 818-27 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Characterization of cardiac repolarization in the Göttingen minipig

    Laursen, M., Olesen, Søren-Peter, Grunnet, Morten, Mow, T., Jespersen, T. & Jespersen, Thomas, 2011, In: Journal of Pharmacological and Toxicological Methods. 63, 2, p. 186-95 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Mutations in sodium channel {beta}-subunit SCN3B are associated with early-onset lone atrial fibrillation

    Olesen, M. S., Jespersen, Thomas, Nielsen, J. B., Liang, B., Møller, D. V., Hedley, P., Christiansen, M., Varro, A., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole & Svendsen, Jesper Hastrup, 2011, In: Cardiovascular Research. 89, 4, p. 786-793 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing

    Quinn, T. A., Granite, S., Allessie, M. A., Antzelevitch, C., Bollensdorff, C., Bub, G., Burton, R. A. B., Cerbai, E., Chen, P. S., Delmar, M., Difrancesco, D., Earm, Y. E., Efimov, I. R., Egger, M., Entcheva, E., Fink, M., Fischmeister, R., Franz, M. R., Garny, A., Giles, W. R. & 40 others, Hannes, T., Harding, S. E., Hunter, P. J., Iribe, G., Jalife, J., Johnson, C. R., Kass, R. S., Kodama, I., Koren, G., Lord, P., Markhasin, V. S., Matsuoka, S., McCulloch, A. D., Mirams, G. R., Morley, G. E., Nattel, S., Noble, D., Olesen, Søren-Peter, Panfilov, A. V., Trayanova, N. A., Ravens, U., Richard, S., Rosenbaum, D. S., Rudy, Y., Sachs, F., Sachse, F. B., Saint, D. A., Schotten, U., Solovyova, O., Taggart, P., Tung, L., Varró, A., Volders, P. G., Wang, K., Weiss, J. N., Wettwer, E., White, E., Wilders, R., Winslow, R. L. & Kohl, P., 2011, In: Progress in Biophysics & Molecular Biology. 107, 1, p. 4-10 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Chronic sympathetic activation promotes downregulation of ß-adrenoceptor-mediated effects in the guinea pig heart independently of structural remodeling and systolic dysfunction

    Soltysinska, E., Thiele, S., Osadchiy, O. & Olesen, Søren-Peter, 2011, In: Pflügers Archiv - European Journal of Physiology. 462, 4, p. 529-43 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Myocardial structural, contractile and electrophysiological changes in the guinea-pig heart failure model induced by chronic sympathetic activation

    Soltysinska, E., Osadchiy, O. & Olesen, Søren-Peter, 2011, In: Experimental Physiology. 96, 7, p. 647-63 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2010
  10. Published

    Differential expression of hERG1 channel isoforms reproduces properties of native I(Kr) and modulates cardiac action potential characteristics

    Larsen, A. P. & Olesen, Søren-Peter, 2010, In: P L o S One. 5, 2, p. e9021

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Identification of a Kir3.4 Mutation in Congenital Long QT Syndrome

    Yang, Y., Yang, Y., Liang, B., Liu, J., Li, J., Grunnet, M., Olesen, S-P., Rasmussen, H. B., Ellinor, P. T., Gao, L., Lin, X., Li, L., Wang, L., Xiao, J., Liu, Y., Liu, Y., Zhang, S., Liang, D., Peng, L., Jespersen, T. & 1 others, Chen, Y., 2010, In: American Journal of Human Genetics. 86, 6, p. 872-80 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 2009
  13. Published

    Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury

    Bentzen, Bo Hjorth, Osadchii, O., Jespersen, Thomas, Hansen, R. S., Olesen, Søren-Peter & Grunnet, Morten, 2009, In: Pflügers Archiv: European Journal of Physiology. 457, 5, p. 979-88 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Synthesis and characterisation of NS13558: a new important tool for addressing KCa1.1 channel function ex vivo

    Bentzen, Bo Hjorth, Andersen, R. W., Olesen, Søren-Peter, Grunnet, Morten & Nardi, A., 2009, In: NAUNYN-SCHMIEDEBERGS ARCHIV FUR EXPERIMENTELLE PATHOLOGIE UND PHARMAKOLOGIE.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle

    Callø, Kirstine, Soltysinska, E., Jespersen, Thomas, Lundby, Alicia, Antzelevitch, C., Olesen, Søren-Peter & Cordeiro, J. M., 2009, In: Journal of Molecular and Cellular Cardiology. 48, 1, p. 191-200 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Functional properties of human neuronal Kv11 channels

    Einarsen, K., Callø, Kirstine, Grunnet, Morten, Olesen, Søren-Peter & Schmitt, Nicole, 2009, In: Pflügers Archiv: European Journal of Physiology. 458, 4, p. 689-700 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Bureaukrati, Bogholderi og Bullshit

    Harder, Peter, Bache, C., Flensted-Jensen, M., Koch, Lene, Olesen, Søren-Peter & Sand-Jensen, Kaj, 30 Oct 2009, In: Weekendavisen.

    Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication

  18. Published

    Forskning skal ikke gøre ledelsen glad

    Harder, Peter, Bache, C., Flensted-Jensen, M., Koch, Lene, Olesen, Søren-Peter & Sand-Jensen, Kaj, 11 Feb 2009, In: Universitetsavisen.

    Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication

  19. Published

    Kvalitet og styring i fremtidens universiteter - Ejerskab, ledelseskultur og de faktiske følger af universitetsloven: Forskningspolitisk årsmøde 2009

    Harder, Peter, Bache, C., Flensted-Jensen, M., Koch, Lene, Olesen, Søren-Peter & Sand-Jensen, Kaj, 2009, 78 p. Det Kongelige Danske Videnskabernes Selskab.

    Research output: Other contribution › Communication

  20. Published

    BK channel activation by NS11021 decreases excitability and contractility of urinary bladder smooth muscle

    Layne, J. J., Nausch, B., Olesen, Søren-Peter & Nelson, M. T., 2009, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 298, 2, p. R378-84

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Chamber-specific effects of hypokalaemia on ventricular arrhythmogenicity in isolated, perfused guinea-pig heart

    Osadchii, O. E., Bentzen, Bo Hjorth & Olesen, Søren-Peter, 2009, In: Experimental Physiology. 94, 4, p. 434-46 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts

    Soltysinska, E., Olesen, Søren-Peter, Christ, T., Wettwer, E., Varró, A., Grunnet, Morten & Jespersen, Thomas, 2009, In: Pflügers Archiv: European Journal of Physiology. 459, 1, p. 11-23 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Ventricular tachycardia in an Brugada syndrome patient caused by novel deletion mutation in SCN5A

    Tfelt-Hansen, Jacob, Jespersen, T., Hofman-Bang, J., Rasmussen, H., Cedergreen, P. K., Skovby, F., Abriel, H., Svendsen, J., Olesen, Søren-Peter & Christiansen & Haunso, S., 2009, In: Canadian Journal of Cardiology. 25, 3

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Arvelige hjertesygdomme forårsaget af natriumkanalmutationer

    Tfelt-Hansen, J., Olesen, Søren-Peter, Svendsen, Jesper Hastrup & Jespersen, Thomas, 2009, In: Ugeskrift for læger. 171, 15, p. 1261-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2008
  26. Published

    A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome

    Callø, Kirstine, Cordeiro, J. M., Di Diego, J. M., Hansen, R. S., Grunnet, Morten, Olesen, Søren-Peter & Antzelevitch, C., 2008, In: Cardiovascular Research. 81, 4, p. 686-94 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Antiarrhythmic properties of a rapid delayed-rectifier current activator in rabbit models of acquired long QT syndrome.

    Diness, T. G., Yeh, Y., Qi, X. Y., Chartier, D., Tsuji, Y., Hansen, R. S., Olesen, Søren-Peter, Grunnet, Morten & Nattel, S., 2008, In: Cardiovascular Research. 79, 1, p. 61-69 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Single-copy insertion of transgenes in Caenorhabditis elegans.

    Frøkjær-Jensen, Christian, Davis, M. W., Hopkins, C. E., Newman, B. J., Thummel, J. M., Olesen, Søren-Peter, Grunnet, Morten & Jorgensen, E. M., 2008, In: Nature Genetics. 40, 11, p. 1375-83 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Biophysical characterization of the short QT mutation hERG-N588K reveals a mixed gain-and loss-of-function

    Grunnet, Morten, Diness, T. G., Hansen, R. S. & Olesen, Søren-Peter, 2008, In: Cellular Physiology and Biochemistry. 22, 5-6, p. 611-624 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    In vivo effects of the IKr agonist NS3623 on cardiac electrophysiology of the guinea pig.

    Hansen, R. S., Olesen, Søren-Peter, Rønn, L. C. B. & Grunnet, Morten, 2008, In: Journal of Cardiovascular Pharmacology. 52, 1, p. 35-41 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Phosphatidylinositol-bisphosphate regulates intercellular coupling in cardiac myocytes

    Hofgaard, J. P., Banach, K., Mollerup, S., Jørgensen, H. K., Olesen, Søren-Peter, von Holstein-Rathlou, Niels-Henrik & Nielsen, Morten Schak, 2008, In: Pflügers Archiv: European Journal of Physiology. 457, 2, p. 303-13 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Effects of potassium channel openers in the isolated perfused hypokalaemic murine heart

    Killeen, M. J., Thomas, G., Olesen, Søren-Peter, Demnitz, J., Stokoe, K. S., Grace, A. A. & Huang, C. L. H., 2008, In: Acta Physiologica (Print Edition). 193, 1, p. 25-36 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Forskeren i samfundet: Forskningspolitisk årsmøde 2008

    Kærgård, Niels, Harder, Peter, Bache, C., Flensted-Jensen, M., Koch, Lene, Olesen, Søren-Peter & Sand-Jensen, Kaj, 2008, Det Kongelige Danske Videnskabernes Selskab. 42 p.

    Research output: Book/Report › Book

  34. Published

    Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current.

    Larsen, A. P., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, 2008, In: Pflügers Archiv: European Journal of Physiology. 456, 6, p. 1137-48 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    KCNE3 mutation V17M identified in a patient with lone atrial fibrillation.

    Lundby, Alicia, Ravn, L. S., Svendsen, J. H., Hauns, S., Olesen, Søren-Peter & Schmitt, Nicole, 2008, In: Cellular Physiology and Biochemistry. 21, 1-3, p. 47-54 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    BK channel modulators: a comprehensive overview.

    Nardi, A. & Olesen, Søren-Peter, 2008, In: Current Medicinal Chemistry. 15, 11, p. 1126-46 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Computational analysis of the effects of the hERG channel opener NS1643 in a human ventricular cell model.

    Peitersen, T., Grunnet, Morten, Benson, A. P., Holden, A. V., von Holstein-Rathlou, Niels-Henrik & Olesen, Søren-Peter, 2008, In: Heart Rhythm. 5, 5, p. 734-41 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. 2007
  39. Published

    The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels.

    Bentzen, Bo Hjorth, Nardi, A., Callø, Kirstine, Madsen, L. S., Olesen, Søren-Peter & Grunnet, Morten, 2007, In: Molecular Pharmacology. 72, 4, p. 1033-44 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit.

    Callø, Kirstine, Ravn, L. S., Schmitt, Nicole, Sui, J. L., Duno, M., Haunso, S., Grunnet, Morten, Svendsen, J. H. & Olesen, Søren-Peter, 2007, In: Biochemical and Biophysical Research Communications. 364, 4, p. 889-95 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Activation of ERG2 potassium channels by the diphenylurea NS1643.

    Elmedyb, P., Olesen, Søren-Peter & Grunnet, Morten, 2007, In: Neuropharmacology. 53, 2, p. 283-94 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Modulation of ERG channels by XE991.

    Elmedyb, P., Callø, Kirstine, Schmitt, Nicole, Hansen, R. S., Grunnet, Morten & Olesen, Søren-Peter, 2007, In: Basic & Clinical Pharmacology & Toxicology. 100, 5, p. 316-22 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Pharmacological activation of rapid delayed rectifier potassium current suppresses bradycardia-induced triggered activity in the isolated guinea pig heart.

    Hansen, R. S., Olesen, Søren-Peter & Grunnet, Morten, 2007, In: Journal of Pharmacology and Experimental Therapeutics. 321, 3, p. 996-1002 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Inactivation as a new regulatory mechanism for neuronal Kv7 channels.

    Jensen, H. S., Grunnet, Morten & Olesen, Søren-Peter, 2007, In: Biophysical Journal. 92, 8, p. 2747-56 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family.

    Jespersen, Thomas, Membrez, M., Nicolas, C. S., Pitard, B., Staub, O., Olesen, Søren-Peter, Baró, I. & Abriel, H., 2007, In: Cardiovascular Research. 74, 1, p. 64-74 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Forsknings- og ytringsfriheden på universiteterne: forskningspolitisk årsmøde 2007

    Kærgård, Niels, Bache, C., Flensted-Jensen, M., Harder, Peter, Olesen, Søren-Peter & Wewer, Ulla M., 2007, København: Det Kongelige Danske Videnskabernes Selskab.

    Research output: Book/Report › Book

  47. Published

    KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval.

    Lundby, Alicia, Ravn, L. S., Svendsen, Jesper Hastrup, Olesen, Søren-Peter & Schmitt, Nicole, 2007, In: Heart Rhythm. 4, 12, p. 1532-41 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Acrylamides as potassium channel openers

    Nardit, A. & Olesen, Søren-Peter, 2007, In: Expert Opinion on Therapeutic Patents. 17, 10, p. 1215-1226 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Mutations in the Kv1.5 channel gene KCNA5 in cardiac arrest patients.

    Nielsen, N. H., Winkel, B. G., Kanters, Jørgen K., Schmitt, Nicole, Hofman-Bang, J., Jensen, H. S., Bentzen, Bo Hjorth, Sigurd, B., Larsen, Lars Allan, Andersen, P. S., Kjeldsen, K., Grunnet, Morten, Christiansen, M., Olesen, Søren-Peter & Haunsø, Stig, 2007, In: Biochemical and Biophysical Research Communications. 354, 3, p. 776-82 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment.

    Rasmussen, Hanne Borger, Frøkjær-Jensen, Christian, Jensen, C. S., Jensen, H. S., Jørgensen, N. K., Misonou, H., Trimmer, J. S., Olesen, Søren-Peter & Schmitt, Nicole, 2007, In: Journal of Cell Science. 120, Pt 6, p. 953-63 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. 2006
  52. Published

    The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels.

    Bentzen, Bo Hjorth, Schmitt, Nicole, Callø, Kirstine, Dalby Brown, W., Grunnet, Morten & Olesen, Søren-Peter, 2006, In: Neuropharmacology. 51, 6, p. 1068-77 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Mechanism of action of NS1643, a novel hERG channel activator

    Casis, O., Olesen, Søren-Peter & Sanguinetti, M. C., 2006, In: Molecular Pharmacology. 69, p. 658-665

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    K(v)7 channels: Function, pharmacology and channel modulators

    Dalby-Brown, W., Hansen, H. H., Korsgaard, M. P. G., Mirza, N. & Olesen, Søren-Peter, 2006, In: Current Topics in Medicinal Chemistry. 6, 10, p. 999-1023 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Frequency-dependent modulation of KCNQ1 and HERG1 potassium channels.

    Diness, T. G., Hansen, R. S., Olesen, Søren-Peter & Grunnet, Morten, 2006, In: Biochemical and Biophysical Research Communications. 343, 4, p. 1224-33 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Activation of HERG potassium channels by the diphenylurea NS1643

    Hansen, R. S., Diness, T. G., Christ, T., Demnitz, J., Ravens, U. & Olesen, Søren-Peter, 2006, In: Molecular Pharmacology. 69, p. 266-277

    Research output: Contribution to journal › Journal article › Research › peer-review

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