Anne-Vibeke Lænkholm
Clinical Associate Professor
- 2020
- Published
The Prosigna 50-gene profile and responsiveness to adjuvant anthracycline-based chemotherapy in high-risk breast cancer patients
Jensen, M., Lænkholm, Anne-Vibeke, Balslev, E., Buckingham, W., Ferree, S., Glavicic, V., Dupont Jensen, J., Søegaard Knoop, A., Mouridsen, H. T., Nielsen, D., Nielsen, T. O. & Ejlertsen, Bent Laursen, 2020, In: npj Breast Cancer. 6, 9 p., 7.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer
Kos, Z., Roblin, E., Kim, R. S., Michiels, S., Gallas, B. D., Chen, W., van de Vijver, K. K., Goel, S., Adams, S., Demaria, S., Viale, G., Nielsen, T. O., Badve, S. S., Symmans, W. F., Sotiriou, C., Rimm, D. L., Hewitt, S., Denkert, C., Loibl, S., Luen, S. J. & 31 others, , 2020, In: npj Breast Cancer. 6, p. 17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population-based Study of Prosigna-PAM50 and Outcome Among Postmenopausal Women With Estrogen Receptor-positive and HER2-negative Operable Invasive Lobular or Ductal Breast Cancer
Lænkholm, Anne-Vibeke, Jensen, M., Eriksen, J. O., Roslind, A., Buckingham, W., Ferree, S., Nielsen, T. & Ejlertsen, Bent Laursen, Aug 2020, In: Clinical Breast Cancer. 20, 4, p. e423-e432 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Breast cancer survival in Nordic BRCA2 mutation carriers-unconventional association with oestrogen receptor status
Olafsdottir, E. J., Borg, A., Jensen, M., Gerdes, Anne-Marie Axø, Johansson, A. L. V., Barkardottir, R. B., Johannsson, O. T., Ejlertsen, Bent Laursen, Sønderstrup, I. M. H., Hovig, E., Lænkholm, Anne-Vibeke, Hansen, T. V. O., Olafsdottir, G. H., Rossing, M., Jonasson, J. G., Sigurdsson, S., Loman, N., Nilsson, M. P., Narod, S. A. & Tryggvadottir, L., Nov 2020, In: British Journal of Cancer. 123, 11, p. 1608-1615 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How current assay approval policies are leading to unintended imprecision medicine
Salgado, R., Bellizzi, A. M., Rimm, D., Bartlett, J. M. S., Nielsen, T., Holger, M., Lænkholm, Anne-Vibeke, Quinn, C., Cserni, G., Cunha, I. W., Alvarado-Cabrero, I. & Cree, I., Nov 2020, In: Lancet Oncology. 21, 11, p. 1399-1401 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Induction of PIK3CA alterations during neoadjuvant letrozole may improve outcome in postmenopausal breast cancer patients
Skriver, S. K., Jensen, M. B., Eriksen, J. O., Ahlborn, L. B., Knoop, A. S., Rossing, M., Ejlertsen, Bent Laursen & Lænkholm, Anne-Vibeke, 2020, In: Breast Cancer Research and Treatment. 184, 1, p. 123-133 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumour-infiltrating lymphocytes and response to neoadjuvant letrozole in patients with early oestrogen receptor-positive breast cancer: analysis from a nationwide phase II DBCG trial
Skriver, S. K., Jensen, M., Knoop, A. S., Ejlertsen, Bent Laursen & Lænkholm, Anne-Vibeke, 14 May 2020, In: Breast cancer research : BCR. 22, 1, 8 p., 46.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses
Zhang, H., Ahearn, T. U., Lecarpentier, J., Barnes, D., Beesley, J., Qi, G., Jiang, X., O'Mara, T. A., Zhao, N., Bolla, M. K., Dunning, A. M., Dennis, J., Wang, Q., Ful, Z. A., Aittomäki, K., Andrulis, I. L., Anton-Culver, H., Arndt, V., Aronson, K. J., Arun, B. K. & 31 others, , Jun 2020, In: Nature Genetics. 52, 6, p. 572-581 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Basal biomarkers nestin and INPP4B predict gemcitabine benefit in metastatic breast cancer: Samples from the phase III SBG0102 clinical trial
Asleh, K., Lyck Carstensen, S., Tykjaer Jørgensen, C. L., Burugu, S., Gao, D., Won, J. R., Jensen, M., Balslev, E., Lænkholm, Anne-Vibeke, Nielsen, Dorte Lisbet, Ejlertsen, Bent Laursen & Nielsen, T. O., 15 May 2019, In: International Journal of Cancer. 144, 10, p. 2578-2586 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collaboration
Leung, S. C. Y., Nielsen, T. O., Zabaglo, L. A., Arun, I., Badve, S. S., Bane, A. L., Bartlett, J. M. S., Borgquist, S., Chang, M. C., Dodson, A., Ehinger, A., Fineberg, S., Focke, C. M., Gao, D., Gown, A. M., Gutierrez, C., Hugh, J. C., Kos, Z., Lænkholm, A. V., Mastropasqua, M. G. & 15 others, , 2019, In: Histopathology. 75, 2, p. 225-235Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of tumor-infiltrating lymphocytes and association with prognosis in BRCA-mutated breast cancer
Sønderstrup, I. M. H., Jensen, M. B., Ejlertsen, Bent Laursen, Eriksen, J. O., Gerdes, Anne-Marie Axø, Kruse, T. A., Larsen, M. J., Thomassen, M. & Lænkholm, Anne-Vibeke, 2019, In: Acta Oncologica. 58, 3, p. 363-370 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subtypes in BRCA-mutated breast cancer
Sønderstrup, I. M. H., Jensen, M. R., Ejlertsen, Bent Laursen, Eriksen, J. O., Gerdes, Anne-Marie Axø, Kruse, T. A., Larsen, M. J., Thomassen, M. & Lænkholm, Anne-Vibeke, Feb 2019, In: Human Pathology. 84, p. 192-201 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Syringomatous Tumour Presenting as Inversion of a Supernumerary Nipple
Öwall, L., Mygind, H., Rosenborg, Å. & Lænkholm, Anne-Vibeke, 2019, In: Case Reports in Pathology. 2019, 9461815 p., 4.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Mortality and recurrence rates among systemically untreated high risk breast cancer patients included in the DBCG 77 trials
Jensen, M. B., Nielsen, T. O., Knoop, A. S., Lænkholm, Anne-Vibeke, Balslev, E. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 135-140Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The clinical database and implementation of treatment guidelines by the Danish Breast Cancer Cooperative Group in 2007–2016
Jensen, M. B., Lænkholm, Anne-Vibeke, Offersen, B. V., Christiansen, P., Kroman, Niels Thorndahl, Mouridsen, H. T. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 13-18Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer
Jensen, M., Lænkholm, Anne-Vibeke, Nielsen, T. O., Eriksen, J. O., Wehn, P., Hood, T., Ram, N., Buckingham, W., Ferree, S. & Ejlertsen, B., 2018, In: Breast cancer research : BCR. 20, 10 p., 79.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Correlation between circulating cell-free PIK3CA tumor DNA levels and treatment response in patients with PIK3CA-mutated metastatic breast cancer
Kodahl, A. R., Ehmsen, S., Pallisgaard, N., Jylling, A. M. B., Jensen, J. D., Lænkholm, Anne-Vibeke, Knoop, A. S. & Ditzel, H. J., 2018, In: Molecular Oncology. 12, 6, p. 925-935 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression
Krøigård, A. B., Larsen, M. J., Lænkholm, Anne-Vibeke, Knoop, A. S., Jensen, J. D., Bak, M., Mollenhauer, J., Thomassen, M. & Kruse, T. A., 2018, In: PLoS ONE. 13, 1, 18 p., e0189887.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An inter-observer Ki67 reproducibility study applying two different assessment methods: on behalf of the Danish Scientific Committee of Pathology, Danish breast cancer cooperative group (DBCG)
Lænkholm, Anne-Vibeke, Grabau, D., Talman, M. M., Balslev, E., Bak Jylling, A. M., Tabor, T. P., Johansen, M., Brügmann, A., Lelkaitis, G., Di Caterino, T., Mygind, H., Poulsen, T., Mertz, H., Søndergaard, G. & Rasmussen, B. B., 2018, In: Acta Oncologica. 57, 1, p. 83-89 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Williams syndrome transcription factor (WSTF) acts as an activator of estrogen receptor signaling in breast cancer cells and the effect can be abrogated by 1α,25-dihydroxyvitamin D3
Lundqvist, J., Kirkegaard, T., Lænkholm, Anne-Vibeke, Duun-Henriksen, A. K., Bak, M., Feldman, D. & Lykkesfeldt, A. E., 2018, In: The Journal of Steroid Biochemistry and Molecular Biology. 177, p. 171-178Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PAM50 Risk of Recurrence Score Predicts 10-Year Distant Recurrence in a Comprehensive Danish Cohort of Postmenopausal Women Allocated to 5 Years of Endocrine Therapy for Hormone Receptor-Positive Early Breast Cancer
Lænkholm, Anne-Vibeke, Jensen, M., Eriksen, J. O., Rasmussen, B. B., Knoop, A. S., Buckingham, W., Ferree, S., Schaper, C., Nielsen, T. O., Haffner, T., Kibøl, T., Møller Talman, M., Bak Jylling, A. M., Tabor, T. P. & Ejlertsen, B., 2018, In: Journal of Clinical Oncology. 36, 8, p. 735-740Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ability of PAM50 risk of recurrence score to predict 10-year distant recurrence in hormone receptor-positive postmenopausal women with special histological subtypes
Lænkholm, Anne-Vibeke, Jensen, M., Eriksen, J. O., Buckingham, W., Ferree, S., Nielsen, T. O. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 44-50Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Provision of data from the clinical database and of biological material from the tumor bank of the Danish Breast Cancer Cooperative Group 2008–2017
Mouridsen, H., Christiansen, P., Jensen, M. B., Lænkholm, Anne-Vibeke, Flyger, H., Offersen, B., Vejborg, I. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 154-156 3 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Is DBCG abreast of new developments?
Offersen, B. V., Ejlertsen, B., Balslev, E., Flyger, H., Gerdes, Anne-Marie Axø, Hansen, M. K., Hølmich, Lisbet Rosenkrantz, Jensen, M., Kristensen, B., Lænkholm, Anne-Vibeke, Mouridsen, H. T., Nielsen, M. H., Overgaard, J., Tuxen, M., Vejborg, I. & Christiansen, P., 2018, In: Acta Oncologica. 57, 1, p. 1-2 2 p.Research output: Contribution to journal › Editorial › Research
- Published
Neoadjuvant letrozole for postmenopausal estrogen receptor-positive, HER2-negative breast cancer patients, a study from the Danish Breast Cancer Cooperative Group (DBCG)
Skriver, S. K., Lænkholm, Anne-Vibeke, Rasmussen, B. B., Handler, J., Grundtmann, B., Tvedskov, Tove Filtenborg, Christiansen, P., Knoop, A. S., Jensen, M. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 31-37 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 102813499
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Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
83
downloads
The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
82
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Genomic Analyses of Breast Cancer Progression Reveal Distinct Routes of Metastasis Emergence
Research output: Contribution to journal › Journal article › Research › peer-review
Published