Anne-Vibeke Lænkholm

Anne-Vibeke Lænkholm

Clinical Associate Professor


  1. 2020
  2. Published

    The Prosigna 50-gene profile and responsiveness to adjuvant anthracycline-based chemotherapy in high-risk breast cancer patients

    Jensen, M., Lænkholm, Anne-Vibeke, Balslev, E., Buckingham, W., Ferree, S., Glavicic, V., Dupont Jensen, J., Søegaard Knoop, A., Mouridsen, H. T., Nielsen, D., Nielsen, T. O. & Ejlertsen, Bent Laursen, 2020, In: npj Breast Cancer. 6, 9 p., 7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

    Kos, Z., Roblin, E., Kim, R. S., Michiels, S., Gallas, B. D., Chen, W., van de Vijver, K. K., Goel, S., Adams, S., Demaria, S., Viale, G., Nielsen, T. O., Badve, S. S., Symmans, W. F., Sotiriou, C., Rimm, D. L., Hewitt, S., Denkert, C., Loibl, S., Luen, S. J. & 31 others, Bartlett, J. M. S., Savas, P., Pruneri, G., Dillon, D. A., Cheang, M. C. U., Tutt, A., Hall, J. A., Kok, M., Horlings, H. M., Madabhushi, A., van der Laak, J., Ciompi, F., Lænkholm, Anne-Vibeke, Bellolio, E., Gruosso, T., Fox, S. B., Araya, J. C., Floris, G., Hudeček, J., Voorwerk, L., Beck, A. H., Kerner, J., Larsimont, D., Declercq, S., Van den Eynden, G., Pusztai, L., Ehinger, A., Singh, R., Balslev, E., Stovgaard, Elisabeth Ida Specht & International Immuno-Oncology Biomarker Working Group, I. I. B. W. G., 2020, In: npj Breast Cancer. 6, p. 17

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Population-based Study of Prosigna-PAM50 and Outcome Among Postmenopausal Women With Estrogen Receptor-positive and HER2-negative Operable Invasive Lobular or Ductal Breast Cancer

    Lænkholm, Anne-Vibeke, Jensen, M., Eriksen, J. O., Roslind, A., Buckingham, W., Ferree, S., Nielsen, T. & Ejlertsen, Bent Laursen, Aug 2020, In: Clinical Breast Cancer. 20, 4, p. e423-e432 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Breast cancer survival in Nordic BRCA2 mutation carriers-unconventional association with oestrogen receptor status

    Olafsdottir, E. J., Borg, A., Jensen, M., Gerdes, Anne-Marie Axø, Johansson, A. L. V., Barkardottir, R. B., Johannsson, O. T., Ejlertsen, Bent Laursen, Sønderstrup, I. M. H., Hovig, E., Lænkholm, Anne-Vibeke, Hansen, T. V. O., Olafsdottir, G. H., Rossing, M., Jonasson, J. G., Sigurdsson, S., Loman, N., Nilsson, M. P., Narod, S. A. & Tryggvadottir, L., Nov 2020, In: British Journal of Cancer. 123, 11, p. 1608-1615 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    How current assay approval policies are leading to unintended imprecision medicine

    Salgado, R., Bellizzi, A. M., Rimm, D., Bartlett, J. M. S., Nielsen, T., Holger, M., Lænkholm, Anne-Vibeke, Quinn, C., Cserni, G., Cunha, I. W., Alvarado-Cabrero, I. & Cree, I., Nov 2020, In: Lancet Oncology. 21, 11, p. 1399-1401 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  7. Published

    Induction of PIK3CA alterations during neoadjuvant letrozole may improve outcome in postmenopausal breast cancer patients

    Skriver, S. K., Jensen, M. B., Eriksen, J. O., Ahlborn, L. B., Knoop, A. S., Rossing, M., Ejlertsen, Bent Laursen & Lænkholm, Anne-Vibeke, 2020, In: Breast Cancer Research and Treatment. 184, 1, p. 123-133 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Tumour-infiltrating lymphocytes and response to neoadjuvant letrozole in patients with early oestrogen receptor-positive breast cancer: analysis from a nationwide phase II DBCG trial

    Skriver, S. K., Jensen, M., Knoop, A. S., Ejlertsen, Bent Laursen & Lænkholm, Anne-Vibeke, 14 May 2020, In: Breast cancer research : BCR. 22, 1, 8 p., 46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

    Zhang, H., Ahearn, T. U., Lecarpentier, J., Barnes, D., Beesley, J., Qi, G., Jiang, X., O'Mara, T. A., Zhao, N., Bolla, M. K., Dunning, A. M., Dennis, J., Wang, Q., Ful, Z. A., Aittomäki, K., Andrulis, I. L., Anton-Culver, H., Arndt, V., Aronson, K. J., Arun, B. K. & 31 others, Auer, P. L., Azzollini, J., Barrowdale, D., Becher, H., Beckmann, M. W., Behrens, S., Benitez, J., Bermisheva, M., Bialkowska, K., Blanco, A., Blomqvist, C., Bogdanova, N. V., Bojesen, Stig Egil, Bonanni, B., Bondavalli, D., Borg, A., Brauch, H., Brenner, H., Briceno, I., Broeks, A., Brucker, S. Y., Brüning, T., Burwinkel, B., Buys, S. S., Byers, H., Caldés, T., Caligo, M. A., Christiansen, H., Lænkholm, Anne-Vibeke, Nielsen, Finn Cilius & kConFab Investigators, K. I., Jun 2020, In: Nature Genetics. 52, 6, p. 572-581 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2019
  11. Published

    Basal biomarkers nestin and INPP4B predict gemcitabine benefit in metastatic breast cancer: Samples from the phase III SBG0102 clinical trial

    Asleh, K., Lyck Carstensen, S., Tykjaer Jørgensen, C. L., Burugu, S., Gao, D., Won, J. R., Jensen, M., Balslev, E., Lænkholm, Anne-Vibeke, Nielsen, Dorte Lisbet, Ejlertsen, Bent Laursen & Nielsen, T. O., 15 May 2019, In: International Journal of Cancer. 144, 10, p. 2578-2586 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collaboration

    Leung, S. C. Y., Nielsen, T. O., Zabaglo, L. A., Arun, I., Badve, S. S., Bane, A. L., Bartlett, J. M. S., Borgquist, S., Chang, M. C., Dodson, A., Ehinger, A., Fineberg, S., Focke, C. M., Gao, D., Gown, A. M., Gutierrez, C., Hugh, J. C., Kos, Z., Lænkholm, A. V., Mastropasqua, M. G. & 15 others, Moriya, T., Nofech-Mozes, S., Osborne, C. K., Penault-Llorca, F. M., Piper, T., Sakatani, T., Salgado, R., Starczynski, J., Sugie, T., van der Vegt, B., Viale, G., Hayes, D. F., McShane, L. M., Dowsett, M. & on behalf of the International Ki67 in Breast Cancer Working Group of the Breast International Group and North American Breast Cancer Group (BIG-NABCG), O. B. O. T. I. K. I. B. C. W. G. O. T. B. I. G. A. N. A. B. C. G. (., 2019, In: Histopathology. 75, 2, p. 225-235

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Evaluation of tumor-infiltrating lymphocytes and association with prognosis in BRCA-mutated breast cancer

    Sønderstrup, I. M. H., Jensen, M. B., Ejlertsen, Bent Laursen, Eriksen, J. O., Gerdes, Anne-Marie Axø, Kruse, T. A., Larsen, M. J., Thomassen, M. & Lænkholm, Anne-Vibeke, 2019, In: Acta Oncologica. 58, 3, p. 363-370 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Subtypes in BRCA-mutated breast cancer

    Sønderstrup, I. M. H., Jensen, M. R., Ejlertsen, Bent Laursen, Eriksen, J. O., Gerdes, Anne-Marie Axø, Kruse, T. A., Larsen, M. J., Thomassen, M. & Lænkholm, Anne-Vibeke, Feb 2019, In: Human Pathology. 84, p. 192-201 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Syringomatous Tumour Presenting as Inversion of a Supernumerary Nipple

    Öwall, L., Mygind, H., Rosenborg, Å. & Lænkholm, Anne-Vibeke, 2019, In: Case Reports in Pathology. 2019, 9461815 p., 4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2018
  17. Published

    Mortality and recurrence rates among systemically untreated high risk breast cancer patients included in the DBCG 77 trials

    Jensen, M. B., Nielsen, T. O., Knoop, A. S., Lænkholm, Anne-Vibeke, Balslev, E. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 135-140

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The clinical database and implementation of treatment guidelines by the Danish Breast Cancer Cooperative Group in 2007–2016

    Jensen, M. B., Lænkholm, Anne-Vibeke, Offersen, B. V., Christiansen, P., Kroman, Niels Thorndahl, Mouridsen, H. T. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 13-18

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer

    Jensen, M., Lænkholm, Anne-Vibeke, Nielsen, T. O., Eriksen, J. O., Wehn, P., Hood, T., Ram, N., Buckingham, W., Ferree, S. & Ejlertsen, B., 2018, In: Breast cancer research : BCR. 20, 10 p., 79.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Correlation between circulating cell-free PIK3CA tumor DNA levels and treatment response in patients with PIK3CA-mutated metastatic breast cancer

    Kodahl, A. R., Ehmsen, S., Pallisgaard, N., Jylling, A. M. B., Jensen, J. D., Lænkholm, Anne-Vibeke, Knoop, A. S. & Ditzel, H. J., 2018, In: Molecular Oncology. 12, 6, p. 925-935 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression

    Krøigård, A. B., Larsen, M. J., Lænkholm, Anne-Vibeke, Knoop, A. S., Jensen, J. D., Bak, M., Mollenhauer, J., Thomassen, M. & Kruse, T. A., 2018, In: PLoS ONE. 13, 1, 18 p., e0189887.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    An inter-observer Ki67 reproducibility study applying two different assessment methods: on behalf of the Danish Scientific Committee of Pathology, Danish breast cancer cooperative group (DBCG)

    Lænkholm, Anne-Vibeke, Grabau, D., Talman, M. M., Balslev, E., Bak Jylling, A. M., Tabor, T. P., Johansen, M., Brügmann, A., Lelkaitis, G., Di Caterino, T., Mygind, H., Poulsen, T., Mertz, H., Søndergaard, G. & Rasmussen, B. B., 2018, In: Acta Oncologica. 57, 1, p. 83-89 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Williams syndrome transcription factor (WSTF) acts as an activator of estrogen receptor signaling in breast cancer cells and the effect can be abrogated by 1α,25-dihydroxyvitamin D3

    Lundqvist, J., Kirkegaard, T., Lænkholm, Anne-Vibeke, Duun-Henriksen, A. K., Bak, M., Feldman, D. & Lykkesfeldt, A. E., 2018, In: The Journal of Steroid Biochemistry and Molecular Biology. 177, p. 171-178

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    PAM50 Risk of Recurrence Score Predicts 10-Year Distant Recurrence in a Comprehensive Danish Cohort of Postmenopausal Women Allocated to 5 Years of Endocrine Therapy for Hormone Receptor-Positive Early Breast Cancer

    Lænkholm, Anne-Vibeke, Jensen, M., Eriksen, J. O., Rasmussen, B. B., Knoop, A. S., Buckingham, W., Ferree, S., Schaper, C., Nielsen, T. O., Haffner, T., Kibøl, T., Møller Talman, M., Bak Jylling, A. M., Tabor, T. P. & Ejlertsen, B., 2018, In: Journal of Clinical Oncology. 36, 8, p. 735-740

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The ability of PAM50 risk of recurrence score to predict 10-year distant recurrence in hormone receptor-positive postmenopausal women with special histological subtypes

    Lænkholm, Anne-Vibeke, Jensen, M., Eriksen, J. O., Buckingham, W., Ferree, S., Nielsen, T. O. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 44-50

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Provision of data from the clinical database and of biological material from the tumor bank of the Danish Breast Cancer Cooperative Group 2008–2017

    Mouridsen, H., Christiansen, P., Jensen, M. B., Lænkholm, Anne-Vibeke, Flyger, H., Offersen, B., Vejborg, I. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 154-156 3 p.

    Research output: Contribution to journalComment/debateResearch

  27. Published

    Is DBCG abreast of new developments?

    Offersen, B. V., Ejlertsen, B., Balslev, E., Flyger, H., Gerdes, Anne-Marie Axø, Hansen, M. K., Hølmich, Lisbet Rosenkrantz, Jensen, M., Kristensen, B., Lænkholm, Anne-Vibeke, Mouridsen, H. T., Nielsen, M. H., Overgaard, J., Tuxen, M., Vejborg, I. & Christiansen, P., 2018, In: Acta Oncologica. 57, 1, p. 1-2 2 p.

    Research output: Contribution to journalEditorialResearch

  28. Published

    Neoadjuvant letrozole for postmenopausal estrogen receptor-positive, HER2-negative breast cancer patients, a study from the Danish Breast Cancer Cooperative Group (DBCG)

    Skriver, S. K., Lænkholm, Anne-Vibeke, Rasmussen, B. B., Handler, J., Grundtmann, B., Tvedskov, Tove Filtenborg, Christiansen, P., Knoop, A. S., Jensen, M. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 31-37 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 102813499