Jens Bukh
Professor
Virology
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-13-84
Member of:
- 2023
- Published
Identification of novel neutralizing determinants for protection against HCV
Alzua, G. P., Pihl, A. F., Offersgaard, Anna Falden, Velázquez-Moctezuma, R., Duarte Hernandez, Carlos Rene, Augestad, Elias Honerød, Fahnøe, Ulrik, Mathiesen, C. K., Krarup, H., Law, M., Prentø, Jannick, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: Hepatology. 73, 3, p. 982-996Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inactivated genotype 1a, 2a and 3a HCV vaccine candidates induced broadly neutralising antibodies in mice
Alzua, G. P., Pihl, A. F., Offersgaard, Anna Falden, Duarte Hernandez, Carlos Rene, Duan, Z., Feng, S., Fahnøe, Ulrik, Sølund, C., Weis, Nina, Law, M., Prentø, Jannick, Christensen, Jan Pravsgaard, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: Gut. 72, 3, p. 560-572Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Role of CTLA-4 in T Cell Exhaustion in Chronic Hepatitis B Virus Infection
Apol, Á. D., Winckelmann, Anni Assing, Duus, R. B., Bukh, Jens & Weis, Nina, 2023, In: Viruses. 15, 5, 1141.Research output: Contribution to journal › Review › Research › peer-review
- Published
Full-length sequence analysis of hepatitis C virus genotype 3b strains and development of an in vivo infectious 3b cDNA clone
Bajpai, P. S., Collignon, Laura Maria F, Sølund, C., Madsen, L. W., Christensen, P. B., Øvrehus, A., Weis, Nina, Holmbeck, Kenn, Fahnøe, Ulrik & Bukh, Jens, 2023, In: Journal of Virology. 97, 12, 23 p., 00925.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential activity of nucleotide analogs against tick-borne encephalitis and yellow fever viruses in human cell lines
Binderup, A., Galli, Andrea, Fossat, Nicolas Julien, Fernandez-Antunez, C., Mikkelsen, L. S., Rivera, Lizandro, Scheel, Troels Kasper Høyer, Fahnøe, Ulrik, Bukh, Jens & Ramirez, S., 2023, In: Virology. 585, p. 179-185 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SARS-CoV-2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID-19 vaccination
Castruita, J. A. S., Schneider, Uffe Vest, Mollerup, S., Leineweber, T. D., Weis, Nina, Bukh, Jens, Pedersen, M. S. & Westh, Henrik T., 2023, In: APMIS. 131, 3, p. 128-132 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SARS-CoV-2 spike HexaPro formulated in aluminium hydroxide and administered in an accelerated vaccination schedule partially protects Syrian Hamsters against viral challenge despite low neutralizing antibody responses
Christensen, D., Polacek, C., Sheward, D. J., Hanke, L., McInerney, G., Murrell, B., Hartmann, Katrine Top, Jensen, Henrik Elvang, Zimmermann, J., Jungersen, G., Illigen, K. E., Isling, L. K., Fernandez-Antunez, C., Ramirez Almeida, Santseharay, Bukh, Jens & Pedersen, Gabriel Kristian, 2023, In: Frontiers in Immunology. 14, 941281.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Glycan Shift on Antibodies against Hepatitis C Virus E2 412–425 Epitope Elicited by Chimeric sHBsAg-Based Virus-Like Particles
Czarnota, A., Offersgaard, Anna Falden, Owsianka, A., Alzua, G. P., Bukh, Jens, Gottwein, Judith Margarete, Patel, A. H., Bienkowska-Szewczyk, K. & Grzyb, K., 2023, In: Microbiology Spectrum. 11, 2, 17 p., e0024523.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of multi-DAA resistance using a novel hepatitis C virus genotype 3a infectious culture system
Fernandez-Antunez, C., Wang, K., Fahnøe, Ulrik, Mikkelsen, L. S., Gottwein, Judith Margarete, Bukh, Jens & Ramirez Almeida, Santseharay, 2023, In: Hepatology. 78, 2, p. 621-636 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of the viral and cellular microRNA interactomes during SARS-CoV-2 infection
Fossat, Nicolas Julien, Lundsgaard, Emma Alberte, Costa, Rui, Rivera, Lizandro, Nielsen, L., Mikkelsen, L. S., Ramirez Almeida, Santseharay, Bukh, Jens & Scheel, Troels Kasper Høyer, 2023, In: Cell Reports. 42, 4, 112282.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms and Consequences of Genetic Variation in Hepatitis C Virus (HCV)
Galli, Andrea & Bukh, Jens, 2023, Viral Fitness and Evolution: Population Dynamics and Adaptive Mechanisms. Springer, p. 237-264 28 p. (Current Topics in Microbiology and Immunology, Vol. 439).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Substitutions in SARS-CoV-2 Mpro Selected by Protease Inhibitor Boceprevir Confer Resistance to Nirmatrelvir
Gammeltoft, Karen Anbro, Zhou, Y., Ryberg, Line Abildgaard, Pham, Long, Binderup, A., Duarte Hernandez, Carlos Rene, Offersgaard, Anna Falden, Fahnøe, Ulrik, Peters, G. H. J., Ramirez Almeida, Santseharay, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: Viruses. 15, 9, 17 p., 1970.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Challenge Inoculum for Hepatitis C Virus Controlled Human Infection Model
Liang, T. J., Law, J. L. M., Pietschmann, T., Ray, S. C., Bukh, Jens, Bull, R., Chung, R. T., Tyrrell, D. L., Houghton, M. & Rice, C. M., 2023, In: Clinical Infectious Diseases. 77, p. S257-S261Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatitis C virus alters the morphology and function of peroxisomes
Martin de Fourchambault, E., Callens, N., Saliou, J. M., Fourcot, M., Delos, O., Barois, N., Thorel, Q., Ramirez Almeida, Santseharay, Bukh, Jens, Cocquerel, L., Bertrand-Michel, J., Marot, G., Sebti, Y., Dubuisson, J. & Rouillé, Y., 2023, In: Frontiers in Microbiology. 14, 1254728.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington's disease
Mullari, M., Fossat, Nicolas Julien, Skotte, Niels Henning, Asenjo-Martinez, A., Humphreys, D. T., Bukh, Jens, Kirkeby, Agnete, Scheel, Troels Kasper Høyer & Nielsen, Michael Lund, 2023, In: Nature Communications. 14, 20 p., 4348.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals
Offersgaard, Anna Falden, Duarte Hernandez, Carlos Rene, Feng, S., Marichal-Gallardo, P., Holmbeck, Kenn, Pihl, A. F., Fernandez-Antunez, C., Alzua, G. P., Hartmann, Katrine Top, Pham, Long, Zhou, Y., Gammeltoft, Karen Anbro, Fahnøe, Ulrik, Schneider, Uffe Vest, Pedersen, Gabriel Kristian, Jensen, Henrik Elvang, Christensen, Jan Pravsgaard, Ramirez Almeida, Santseharay, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: iScience. 26, 2, 105949.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Toward a vaccine against hepatitis C virus
Offersgaard, Anna Falden, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: Science. 380, 6640, p. 37-38 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Renaming of the genus Flavivirus to Orthoflavivirus and extension of binomial species names within the family Flaviviridae
Postler, T. S., Beer, M., Blitvich, B. J., Bukh, Jens, de Lamballerie, X., Drexler, J. F., Imrie, A., Kapoor, A., Karganova, G. G., Lemey, P., Lohmann, V., Simmonds, P., Smith, D. B., Stapleton, J. T. & Kuhn, J. H., 2023, In: Archives of Virology. 168, 9, 224.Research output: Contribution to journal › Review › Research › peer-review
- Published
Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide
Sherwood, A. V., Rivera-Rangel, L. R., Ryberg, L. A., Larsen, H. S., Anker, K. M., Costa, R., Vågbø, C. B., Jakljevič, E., Pham, L. V., Fernandez-Antunez, C., Indrisiunaite, G., Podolska-Charlery, A., Grothen, J. E. R., Langvad, N. W., Fossat, N., Offersgaard, A., Al-Chaer, A., Nielsen, L., Kuśnierczyk, A., Sølund, C. & 8 others, , 2023, In: Nature. 619, p. 811-818Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First-in-human use of a modular capsid virus-like vaccine platform: An open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2
Smit, M. J., Sander, A. F., Ariaans, M. B. P. A., Fougeroux, C., Heinzel, C., Fendel, R., Esen, M., Kremsner, P. G., Ter Heine, R., Wertheim, H. F., Idorn, M., Paludan, S. R., Underwood, A. P., Binderup, A., Ramirez, S., Bukh, J., Soegaard, M., Erdogan, S. M., Gustavsson, T., Clemmensen, S. & 14 others, , 2023, In: The Lancet Microbe. 4, 3, p. e140-e148Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pre-existing, treatment-specific resistance-associated substitutions in hepatitis C virus genotype 1 and 3 and viral RNA titers during treatment with direct-acting antivirals
Sølund, C., Pedersen, M. S., Fahnøe, Ulrik, Filskov, J., Jenssen, H., Weis, Nina, Schønning, Kristian & Bukh, Jens, 2023, In: APMIS. 131, 8, p. 426-433Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Durability and breadth of neutralisation following multiple antigen exposures to SARS-CoV-2 infection and/or COVID-19 vaccination
Underwood, Alexander Paul James, Sølund, C., Fernandez-Antunez, C., Villadsen, S. L., Mikkelsen, L. S., Fahnøe, Ulrik, Bollerup, S., Winckelmann, Anni Assing, Schneider, Uffe Vest, Binderup, A., Vizgirda, G., Sørensen, A. L., Vinten, C. N., Dalegaard, M. I., Ramirez Almeida, Santseharay, Weis, Nina & Bukh, Jens, 2023, In: EBioMedicine. 89, 104475.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Determinants of Mouse Adaptation of Rat Hepacivirus
Wolfisberg, R., Holmbeck, Kenn, Billerbeck, E., Thorselius, Caroline Eva, Batista, M. N., Fahnøe, Ulrik, Lundsgaard, Emma Alberte, Kennedy, Matthew James, Nielsen, L., Rice, C. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 2023, In: Journal of Virology. 97, 4, 17 p., e0181222.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 12437
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416
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Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies
Research output: Contribution to journal › Review › Research › peer-review
Published -
383
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Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies
Research output: Contribution to journal › Journal article › Research › peer-review
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345
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Hypervariable Region 1 in Envelope Protein 2 of Hepatitis C Virus: A Linchpin in Neutralizing Antibody Evasion and Viral Entry
Research output: Contribution to journal › Review › Research › peer-review
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