Oluf Borbye Pedersen

Oluf Borbye Pedersen

Visiting professor, Clinical Professor

Member of:

  • Internal medicine: infection medicine

  • Internal Medicine: Endocrinology


  1. Published

    Development of a type 2 diabetes risk model from a panel of serum biomarkers from the Inter99 cohort

    Kolberg, J. A., Jørgensen, T., Gerwien, R. W., Hamren, S., McKenna, M. P., Moler, E., Rowe, M. W., Urdea, M. S., Xu, X. M., Hansen, T., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2009, In: Diabetes Care. 32, 7, p. 1207-12 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Diabetes in infants may be treated with sulfonylurea as a replacement for insulin

    Lauridsen, M. H., Boesgaard, T. W., Pedersen, Oluf Borbye, Hansen, T. & Hertz, B., 2009, In: Ugeskrift for læger. 171, 23, p. 1923-1924 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Diabetic cats have decreased gut microbial diversity and a lack of butyrate producing bacteria

    Kieler, Ida Nordang, Osto, M., Hugentobler, L., Puetz, Lara Christine, Gilbert, M Thomas P, Hansen, Torben, Pedersen, Oluf Borbye, Reusch, C. E., Zini, E., Lutz, T. A. & Bjørnvad, Charlotte Reinhard, 2019, In: Scientific Reports. 9, p. 1-13 13 p., 4822.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Dietary ascorbic acid and subsequent change in body weight and waist circumference: associations may depend on genetic predisposition to obesity - a prospective study of three independent cohorts

    Larsen, S. C., Ängquist, Lars, Ahluwalia, Tarun Veer Singh, Skaaby, T., Roswall, N., Tjønneland, A., Halkjær, J., Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Heitmann, B. L. & Sørensen, Thorkild I.A., 2014, In: Nutrition Journal. 13, p. 1-11 11 p., 43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Dietary intervention modulates the gut microbiota and improves insulin resistance - a randomized controlled trial in obese postmenopausal women

    Brahe, L. K., Le Chatelier, E., Prifti, E., Kennedy, S., Blædel, T., Håkansson, J., Pedersen, Oluf Borbye, Astrup, A., Ehrlich, S. & Larsen, L. H., 2014, In: Obesity Reviews. 15, Suppl. 2, p. 41-42 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  6. Published

    Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study

    Eriksen, R., Perez, I. G., Posma, J. M., Haid, M., Sharma, S., Prehn, C., Thomas, L. E., Koivula, R. W., Bizzotto, R., Prehn, C., Mari, A., Giordano, G. N., Pavo, I., Schwenk, J. M., De Masi, F., Tsirigos, K. D., Brunak, S., Viñuela, A., Mahajan, A., McDonald, T. J. & 18 others, Kokkola, T., Rutter, F., Teare, H., Hansen, T. H., Fernandez, J., Jones, A., Jennison, C., Walker, M., McCarthy, M. I., Pedersen, Oluf Borbye, Ruetten, H., Forgie, I., Bell, J. D., Pearson, E. R., Franks, P. W., Adamski, J., Holmes, E. & Frost, G., Aug 2020, In: EBioMedicine. 58, p. 102932

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Dietary modulation of the gut microbiota - a randomised controlled trial in obese postmenopausal women

    Brahe, L. K., Le Chatelier, E., Prifti, E., Pons, N., Kennedy, S., Blædel, T., Håkansson, J., Dalsgaard, T. K., Hansen, Torben, Pedersen, Oluf Borbye, Astrup, A., Ehrlich, S. D. & Larsen, L. H., 2015, In: British Journal of Nutrition. 114, 3, p. 406-417 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Dietary patterns predict changes in two-hour post-oral glucose tolerance test plasma glucose concentrations in middle-aged adults

    Lau, C., Toft, U., Tetens, Inge , Carstensen, Bendix, Jørgensen, T., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2009, In: Journal of Nutrition. 139, 3, p. 588-593 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Digital questionnaire platform in the Danish Blood Donor Study

    Burgdorf, K. S., Felsted, N., Mikkelsen, S., Nielsen, Maria Haahr, Thørner, L. W., Pedersen, Oluf Borbye, Sørensen, E., Nielsen, K. R., Bruun, M. T., Werge, Thomas, Erikstrup, C., Hansen, T. & Ullum, H., 12 Jul 2016, In: Computer Methods and Programs in Biomedicine. 135, p. 101-104 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium

    Koivula, R. W., Forgie, I. M., Kurbasic, A., Viñuela, A., Heggie, A., Giordano, G. N., Hansen, T. H., Hudson, M., Koopman, A. D. M., Rutters, F., Siloaho, M., Allin, K. H., Brage, S., Brorsson, C. A., Dawed, A. Y., De Masi, F., Groves, C. J., Kokkola, T., Mahajan, A., Perry, M. H. & 31 others, Rauh, S. P., Ridderstråle, M., Teare, H. J. A., Thomas, E. L., Tura, A., drb459, drb459, White, T., Adamski, J., Bell, J. D., Beulens, J. W., Brunak, Søren, Dermitzakis, E. T., Froguel, P., Frost, G., Gupta, R., Hansen, Torben, Hattersley, A., Jablonka, B., Kaye, J., Laakso, M., McDonald, T. J., Pedersen, Oluf Borbye, Schwenk, J. M., Pavo, I., Mari, A., McCarthy, M. I., Ruetten, H., Walker, M., Pearson, E., Franks, P. W. & IMI-DIRECT consortium, I. C., 2019, In: Diabetologia. 62, 9, p. 1601-1615

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium: Diabetologia

    Koivula, R., Heggie, A., Barnett, A., Cederberg, H., Hansen, T. H., Koopman, A., Ridderstråle, M., Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M., Perry, M., Rauh, S., Siloaho, M., Teare, H. A., Thorand, B., Bell, J., Brunak, S., Frost, G. & 13 others, Jablonka, B., Mari, A., McDonald, T., Dekker, J., Hansen, Torben, Hattersley, A., Laakso, M., Pedersen, Oluf Borbye, Koivisto, V., Ruetten, H., Walker, M., Pearson, E. & Franks, P., 2014, In: Diabetologia. 57, 6, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes

    Ahluwalia, Tarun Veer Singh, Allin, K. H., Sandholt, C. H., Sparsø, T. H., Jørgensen, M. E., Rowe, M., Christensen, C., Brandslund, I., Lauritzen, T., Linneberg, Allan René, Husemoen, L., Jørgensen, T., Hansen, Torben, Grarup, Niels & Pedersen, Oluf Borbye, Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E664-71

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models: [with Author Correction]

    Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., Brasas, V., Webel, H., Benros, M. E., Pedersen, A. G., Chmura, P. J., Jacobsen, U. P., Mari, A., Koivula, R., Mahajan, A., Vinuela, A. & 31 others, Tajes, J. F., Sharma, S., Haid, M., Hong, M., Musholt, P. B., De Masi, F., Vogt, J., Pedersen, H. K., Gudmundsdottir, V., Jones, A., Kennedy, G., Bell, J., Thomas, E. L., Frost, G., Thomsen, Henrik S., Hansen, E., Hansen, T. H., drb459, drb459, Muilwijk, M., Blom, M. T., 't Hart, L. M., Pattou, F., Raverdy, V., Brage, S., Ridderstråle, M., Pedersen, Oluf Borbye, Hansen, Torben, Banasik, Karina, Rasmussen, Simon, Brunak, Søren & IMI-DIRECT consortium, I. C., 2023, In: Nature Biotechnology. 41, 3, p. 399–408 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Discovery of novel heart rate-associated loci using the Exome Chip

    van den Berg, M. E., Warren, H. R., Cabrera, C. P., Verweij, N., Mifsud, B., Haessler, J., Bihlmeyer, N. A., Fu, Y-P., Weiss, S., Lin, H. J., Grarup, N., Li-Gao, R., Pistis, G., Shah, N., Brody, J. A., Müller-Nurasyid, M., Lin, H., Mei, H., Smith, A. V., Lyytikäinen, L-P. & 101 others, Hall, L. M., van Setten, J., Trompet, S., Prins, B. P., Isaacs, A., Radmanesh, F., Marten, J., Entwistle, A., Kors, J. A., Silva, C. T., Alonso, A., Bis, J. C., de Boer, R. A., de Haan, H. G., de Mutsert, R., Dedoussis, G., Dominiczak, A. F., Doney, A. S. F., Ellinor, P. T., Eppinga, R. N., Felix, S. B., Guo, X., Hagemeijer, Y., Hansen, Torben, Harris, T. B., Heckbert, S. R., Huang, P. L., Hwang, S., Kähönen, M., Kanters, Jørgen K., Kolcic, I., Launer, L. J., Li, M., Yao, X. J., Linneberg, Allan René, Liu, S., Macfarlane, P. W., Mangino, M., Morris, A. D., Mulas, A., Murray, A. D., Nelson, C. P., Orrù, M., Padmanabhan, S., Peters, A., Porteous, D. J., Poulter, N., Psaty, B. M., Qi, L., Raitakari, O. T., Rivadeneira, F., Roselli, C., Rudan, I., Sattar, N., Sever, P., Sinner, M. F., Soliman, E. Z., Spector, T. D., Stanton, A. V., Stirrups, K. E., Taylor, K. D., Tobin, M. D., Uitterlinden, A., Vaartjes, I., Hoes, A. W., van der Meer, P., Völker, U., Waldenberger, M., Xie, Z., Zoledziewska, M., Tinker, A., Polasek, O., Rosand, J., Jamshidi, Y., van Duijn, C. M., Zeggini, E., Jukema, J. W., Asselbergs, F. W., Samani, N. J., Lehtimäki, T., Gudnason, V., Wilson, J., Lubitz, S. A., Kääb, S., Sotoodehnia, N., Caulfield, M. J., Palmer, C. N. A., Sanna, S., Mook-Kanamori, D. O., Deloukas, P., Pedersen, Oluf Borbye, Rotter, J. I., Dörr, M., O'Donnell, C. J., Hayward, C., Arking, D. E., Kooperberg, C., van der Harst, P., Eijgelsheim, M., Stricker, B. H. C. & Munroe, P. B., 15 Jun 2017, In: Human Molecular Genetics. 26, 12, p. 2346-2363 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

    Surendran, P., Feofanova, E. V., Lahrouchi, N., Ntalla, I., Karthikeyan, S., Cook, J., Chen, L., Mifsud, B., Yao, C., Kraja, A. T., Cartwright, J. H., Hellwege, J. N., Giri, A., Tragante, V., Thorleifsson, G., Liu, D. J., Prins, B. P., Stewart, I. D., Cabrera, C. P., Eales, J. M. & 34 others, Akbarov, A., Auer, P. L., Bielak, L. F., Bis, J. C., Braithwaite, V. S., Brody, J. A., Daw, E. W., Warren, H. R., Drenos, F., Nielsen, S. F., Faul, J. D., Fauman, E. B., Fava, C., Varga, T. V., Zhao, J. H., Bork-Jensen, J., Grarup, Niels, Hansen, Torben, Have, C. T., Jørgensen, M. E., Karpe, F., Linneberg, Allan René, Pedersen, Oluf Borbye, Rasmussen, K. L., Sun, Y. V., Witte, D. R., Lind, L., Loos, Ruth, Nordestgaard, Børge, LifeLines Cohort Study, L. C. S., EPIC-CVD, E., EPIC-InterAct, E., Understanding Society Scientific Group, U. S. S. G. & Million Veteran Program, M. V. P., 2020, In: Nature Genetics. 52, 12, p. 1314-1332 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

    Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, M., Kristiansen, K., Yvonne Voigt, A., Vestergaard, H., Hercog, R., Igor Costea, P., Roat Kultima, J., Li, J., Jørgensen, T., Levenez, F. & 9 others, Dore, J., Nielsen, H. B., Brunak, Søren, Raes, J., Hansen, Torben, Wang, J., Dusko Ehrlich, S., Bork, P. & Pedersen, Oluf Borbye, 2015, In: Nature. 528, 7581, p. 262-266 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Do gene variants influencing adult adiposity affect birth weight? A population-based study of 24 loci in 4,744 Danish individuals

    Andersson, E. A., Pilgaard, K., Pisinger, C., Harder, M. N., Grarup, Niels, Færch, K., Sandholt, C., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Pedersen, Oluf Borbye & Hansen, T., 1 Jan 2010, In: P L o S One. 5, 12, p. e14190

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Does DNA Methylation of PPARGC1A Influence Insulin Action in First Degree Relatives of Patients with Type 2 Diabetes?

    Gillberg, L., Jacobsen, S., Ribel-Madsen, R., Gjesing, A. M. P., Boesgaard, T. W., Ling, C., Pedersen, Oluf Borbye, Hansen, Torben & Vaag, Allan, 2013, In: P L o S One. 8, 3, p. e58384

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Does genetic predisposition to higher fat expandability attenuate the impact of weight gain on cardiometabolic risk?

    Carrasquilla, Germán D., Linneberg, Allan René, Jørgensen, T., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2019, In: European Journal of Human Genetics. 27, Suppl. 2, p. 1764 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  20. Published

    Dyslipidemia and reference values for fasting plasma lipid concentrations in Danish/North-European White children and adolescents

    Nielsen, T. R. H., Lausten-Thomsen, U., Fonvig, Cilius Esmann, Bøjsøe, C., Pedersen, L., Bratholm, P. S., Hansen, Torben, Pedersen, Oluf Borbye & Holm, Jens-Christian, 28 Apr 2017, In: B M C Pediatrics. 17, 11 p., 116.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families

    Cheyssac, C., Dina, C., Leprêtre, F., Vasseur-Delannoy, V., Dechaume, A., Lobbens, S., Balkau, B., Ruiz, J., Charpentier, G., Pattou, F., Joly, E., Prentki, M., Hansen, Torben, Pedersen, Oluf Borbye, Vaxillaire, M. & Froguel, P., 2006, In: Diabetes. 55, 4, p. 1171-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism

    Mikkelsen, K. H., Frost, M., Bahl, M. I., Licht, T. R., Jensen, U. S., Rosenberg, Jacob, Pedersen, Oluf Borbye, Hansen, Torben, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 12 Nov 2015, In: PLOS ONE. 10, 11, p. 1-14 e0142352.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Effect of a multifactorial intervention on mortality in type 2 diabetes

    Gaede, P., Lund-Andersen, H., Parving, H. & Pedersen, Oluf Borbye, 2008, In: New England Journal of Medicine. 358, 6, p. 580-91 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Effects of a Family-Based Childhood Obesity Treatment Program on Parental Weight Status

    Trier, C., Dahl, M., Stjernholm, T., Nielsen, T. R. H., Bøjsøe, C., Fonvig, C. E., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2016, In: P L o S One. 11, 8, p. 1-11 11 p., e0161921.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Effects of biphasic, basal-bolus or basal insulin analogue treatments on carotid intima-media thickness in patients with type 2 diabetes mellitus: the randomised Copenhagen Insulin and Metformin Therapy (CIMT) trial

    Lundby-Christensen, L., Vaag, A., Tarnow, L., Almdal, T. P., Lund, S. S., Wetterslev, J., Gluud, C., Boesgaard, T. W., Wiinberg, N., Perrild, H., Krarup, T., Snorgaard, O., Gade-Rasmussen, B., Thorsteinsson, B., Røder, M., Mathiesen, E. R., Jensen, T., Vestergaard, H., Hedetoft, C., Breum, L. & 6 others, Duun, E., Sneppen, S. B., Pedersen, Oluf Borbye, Hemmingsen, B., Carstensen, Bendix & Madsbad, Sten, 2016, In: B M J Open. 6, 2, e008377.

    Research output: Contribution to journalJournal articleResearchpeer-review

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