Ruth Loos
Professor
Loos Group
Blegdamsvej 3B, Mærsk Tårnet, 7. sal
2200 København N.
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Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
Kilpeläinen, T. O., Carli, J. F. M., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, Å. K., Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikäinen, L-P., Eriksson, J. & 157 others, , 2016, In: Nature Communications. 7, 14 p., 10494.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 34 others, , 1 Apr 2017, In: PLOS Genetics. 13, 4, e1006528.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas
Hughes, O., Bentley, A. R., Breeze, C. E., Aguet, F., Xu, X., Nadkarni, G., Sun, Q., Lin, B. M., Gilliland, T., Meyer, M. C., Du, J., Raffield, L. M., Kramer, H., Morton, R. W., Gouveia, M. H., Atkinson, E. G., Valladares-Salgado, A., Wacher-Rodarte, N., Dueker, N. D., Guo, X. & 54 others, , 2024, In: Cell Genomics. 4, 1, 13 p., 100468.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits
Teumer, A., Qi, Q., Nethander, M., Aschard, H., Bandinelli, S., Beekman, M., Berndt, S. I., Bidlingmaier, M., Broer, L., Cappola, A., Ceda, G. P., Chanock, S., Chen, M-H., Chen, T. C., Chen, Y-D. I., Chung, J., Del Greco Miglianico, F., Eriksson, J., Ferrucci, L., Friedrich, N. & 31 others, , 29 Jun 2016, In: Aging Cell. 15, 5, p. 811-824 14 p., e1006166.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomic Disorders in CKD across the Lifespan
Verbitsky, M., Krishnamurthy, S., Krithivasan, P., Hughes, D., Khan, A., Marasà, M., Vena, N., Khosla, P., Zhang, J., Lim, T. Y., Glessner, J. T., Weng, C., Shang, N., Shen, Y., Hripcsak, G., Hakonarson, H., Ionita-Laza, I., Levy, B., Kenny, E. E., Loos, R. J. F. & 11 others, , 2023, In: Journal of the American Society of Nephrology : JASN. 34, 4, p. 607-618 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomics and phenomics of body mass index reveals a complex disease network
Huang, J., Huffman, J. E., Huang, Y., Do Valle, Í., Assimes, T. L., Raghavan, S., Voight, B. F., Liu, C., Barabási, A. L., Huang, R. D. L., Hui, Q., Nguyen, X. M. T., Ho, Y. L., Djousse, L., Lynch, J. A., Vujkovic, M., Tcheandjieu, C., Tang, H., Damrauer, S. M., Reaven, P. D. & 19 others, , 2022, In: Nature Communications. 13, 1, 10 p., 7973.Research output: Contribution to journal › Journal article › Research › peer-review
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Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease
Zhou, W., Kanai, M., Wu, K. H. H., Rasheed, H., Tsuo, K., Hirbo, J. B., Wang, Y., Bhattacharya, A., Zhao, H., Namba, S., Surakka, I., Wolford, B. N., Lo Faro, V., Lopera-Maya, E. A., Läll, K., Favé, M. J., Partanen, J. J., Chapman, S. B., Karjalainen, J., Kurki, M. & 54 others, , 2022, In: Cell Genomics. 2, 10, 20 p., 100192.Research output: Contribution to journal › Journal article › Research › peer-review
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Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts
Wang, Y., Namba, S., Lopera-Maya, E. A., Kerminen, S., Tsuo, K., Läll, K., Kanai, M., Zhou, W., Wu, K. H. H., Favé, M. J., Bhatta, L., Awadalla, P., Brumpton, B. M., Deelen, P., Hveem, K., Lo Faro, V., Mägi, R., Murakami, Y., Sanna, S., Smoller, J. W. & 49 others, , 2023, In: Cell Genomics. 3, 1, 18 p., 100241.Research output: Contribution to journal › Journal article › Research › peer-review
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Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice
Spittaels, K., Van den Haute, C., Van Dorpe, J., Geerts, H., Mercken, M., Bruynseels, K., Lasrado, R., Vandezande, K., Laenen, I., Boon, T., Van Lint, J., Vandenheede, J., Moechars, D., Loos, Ruth & Van Leuven, F., 29 Dec 2000, In: The Journal of Biological Chemistry. 275, 52, p. 41340-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Growth in peak aerobic power during adolescence
Geithner, C. A., Thomis, M. A., Vanden Eynde, B., Maes, H. H. M., Loos, Ruth, Peeters, M., Claessens, A. L. M., Vlietinck, R., Malina, R. M. & Beunen, G. P., Sep 2004, In: Medicine and Science in Sports and Exercise. 36, 9, p. 1616-24 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Habitual energy expenditure modifies the association between NOS3 gene polymorphisms and blood pressure
Vimaleswaran, K. S., Franks, P. W., Barroso, I., Brage, S., Ekelund, U., Wareham, N. J. & Loos, Ruth, Mar 2008, In: American Journal of Hypertension. 21, 3, p. 297-302 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Handedness in twins according to zygosity and chorion type: a preliminary report
Derom, C., Thiery, E., Vlietinck, R., Loos, Ruth & Derom, R., Jul 1996, In: Behavior Genetics. 26, 4, p. 407-8 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
Heritability of somatotype components from early adolescence into young adulthood: a multivariate analysis on a longitudinal twin study
Peeters, M. W., Thomis, M. A., Claessens, A. L., Loos, Ruth, Maes, H. H. M., Lysens, R., Vanden Eynde, B., Vlietinck, R. & Beunen, G., 26 Jul 2003, In: Annals of Human Biology. 30, 4, p. 402-18 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: a systematic review
Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD PMDI, A. P., 2023, In: Communications Medicine. 3, 17 p., 133.Research output: Contribution to journal › Journal article › Research › peer-review
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Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
Kanoni, S., Graham, S. E., Wang, Y., Surakka, I., Ramdas, S., Zhu, X., Clarke, S. L., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K. H. H., Ntalla, I., Hui, Q., Klarin, D., Hilliard, A. T., Wang, Z., Xue, C. & 519 others, , 2022, In: Genome Biology. 23, 1, 42 p., 268.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of SNPs in nutrient-sensitive candidate genes and gene-diet interactions on blood lipids: the DiOGenes study
Brahe, L. K., Ängquist, Lars, Larsen, L. H., Vimaleswaran, K. S., Hager, J., Viguerie, N., Loos, Ruth, Handjieva-Darlenska, T., Jebb, S. A., Hlavaty, P., Larsen, T. M., Martinez, J. A., Papadaki, A., Pfeiffer, A. F. H., van Baak, M. A., Sørensen, Thorkild I.A., Holst, C., Langin, D., Astrup, A. & Saris, W. H. M., 2013, In: British Journal of Nutrition. 110, 5, p. 790-796 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Influence of chorionicity on the heritability estimates of blood pressure: a study in twins
Fagard, R. H., Loos, Ruth, Beunen, G., Derom, C. & Vlietinck, R., Jul 2003, In: Journal of Hypertension. 21, 7, p. 1313-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review
ADA/EASD PMDI, A. P., Merino, Jordi, Thuesen, Anne Cathrine Baun, Lepola, Mette Andersen, Clemmensen, Christoffer, Hansen, Torben, Nakabuye, Mariam, Loos, Ruth, Guasch Ferre, Marta & Vilsbøll, Tina, 2024, In: Communications Medicine. 4, 1, 8 p., 66.Research output: Contribution to journal › Journal article › Research › peer-review
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LDL-cholesterol concentrations: a genome-wide association study
Wellcome Trust Case-Control Consortium, W. T. C. C., 9 Feb 2008, In: Lancet Oncology. 371, 9611, p. 483-91 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies
Mesa, J. L., Loos, Ruth, Franks, P. W., Ong, K. K., Luan, J., O'Rahilly, S., Wareham, N. J. & Barroso, I., Mar 2007, In: Diabetes. 56, 3, p. 884-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, D. G. R. A. M. (. C., Sep 2012, In: Nature Genetics. 44, 9, p. 991-1005 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Length of gestation and birthweight in dizygotic twins
Loos, Ruth, Derom, C., Eeckels, R., Derom, R. & Vlietinck, R., 18 Aug 2001, In: Lancet. 358, 9281, p. 560-1 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Machine learning models for blood pressure phenotypes combining multiple polygenic risk scores
Hrytsenko, Y., Shea, B., Elgart, M., Kurniansyah, N., Lyons, G., Morrison, A. C., Carson, A. P., Haring, B., Mitchel, B. D., Psaty, B. M., Jaeger, B. C., Gu, C. C., Kooperberg, C., Levy, D., Lloyd-Jones, D., Choi, E., Brody, J. A., Smith, J. A., Rotter, J. I., Moll, M. & 18 others, , 2023, medRxiv, 41 p.Research output: Working paper › Preprint
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MagicalRsq-X: A cross-cohort transferable genotype imputation quality metric
Sun, Q., Yang, Y., Rosen, J. D., Chen, J., Li, X., Guan, W., Jiang, M-Z., Wen, J., Pace, R. G., Blackman, S. M., Bamshad, M. J., Gibson, R. L., Cutting, G. R., O'Neal, W. K., Knowles, M. R., Kooperberg, C., Reiner, A. P., Raffield, L. M., Carson, A. P., Rich, S. S. & 7 others, , 2024, In: American Journal of Human Genetics. 111, 5, p. 990-995 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mapping the human genetic architecture of COVID-19
Niemi, M. E. K., Karjalainen, J., Liao, R. G., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Andrews, S. J., Kanai, M., Veerapen, K., Fernandez-Cadenas, I., Schulte, E. C., Striano, P., Marttila, M., Minica, C., Marouli, E., Karim, M. A., Wendt, F. R., Savage, J., Sloofman, L. & 41 others, , 2021, In: Nature. 600, p. 472-477Research output: Contribution to journal › Journal article › Research › peer-review
ID: 183694311
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Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
266
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A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
138
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Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
Research output: Contribution to journal › Journal article › Research › peer-review
Published