Helle S. Waagepetersen
Guest Researcher
Department of Drug Design and Pharmacology
Jagtvej 160
2100 København Ø
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Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission
Frigerio, F., Karaca, M., De Roo, M., Mlynárik, V., Jensen, Dorte Skytt, Carobbio, S., Pajęcka, K., Waagepetersen, Helle S., Gruetter, R., Muller, D. & Maechler, P., Nov 2012, In: Journal of Neurochemistry. 123, 3, p. 342-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Deletion of neuronal GLT-1 in mice reveals its role in synaptic glutamate homeostasis and mitochondrial function
McNair, Laura M., Andersen, Jens Velde, Aldana, Blanca, Hohnholt, M. C., Nissen, J. D., Sun, Y., Fischer, K. D., Sonnewald, U., Nyberg, N., Webster, S. C., Kapur, K., Rimmele, T. S., Barone, I., Hawks-Mayer, H., Lipton, J. O., Hodgson, N. W., Aoki, C. J., Rosenberg, P. A. & Waagepetersen, Helle S., 2019, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 25, p. 4847-4863Research output: Contribution to journal › Journal article › Research › peer-review
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Delineation of glutamate pathways and secretory responses in pancreatic islets with ß-cell-specific abrogation of the glutamate dehydrogenase.
Vetterli, L., Carobbio, S., Pournourmohammadi, S., Martin-del-Rio, R., Jensen, Dorte Skytt, Waagepetersen, Helle S., Tamarit-Rodriguez, J. & Maechler, P., 2012, In: Molecular Biology of the Cell. 23, 19, p. 3851-62Research output: Contribution to journal › Journal article › Research › peer-review
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Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase
Vetterli, L., Carobbio, S., Pournourmohammadi, S., Martin-Del-Rio, R., Jensen, Dorte Skytt, Waagepetersen, Helle S., Tamarit-Rodriguez, J. & Maechler, P., Oct 2012, In: Molecular Biology of the Cell. 23, 19, p. 3851-62 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Demonstration of extensive GABA synthesis in the small population of GAD positive neurons in cerebellar cultures by the use of pharmacological tools
Sonnewald, U., Kortner, T. M., Qu, H., Olstad, E., Suñol, C., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 7 Mar 2006, In: Neurochemistry International. 48, 6-7, p. 572-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Demonstration of neuron-glia transfer of precursors for Gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex
Leke, R., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2008, In: Neurochemical Research. 33, 12, p. 2629-2635Research output: Contribution to journal › Journal article › Research › peer-review
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Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine
Leke, R., Bak, Lasse Kristoffer, Anker, M., Melø, T. M., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Portela, L. V., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 1 Apr 2011, In: Neurotoxicity Research. 19, 3, p. 496-510 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Diphenylalanine Peptide Nanowires as a Substrate for Neural Cultures
Walls, Anne Byriel, Dimaki, M., Korsgaard, T., Swiniarska, M. M., Castillo-León, J., Waagepetersen, Helle S. & Svendsen, W. E., 1 Mar 2020, In: BioNanoScience. 10, 1, p. 224-234 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Direct measurement of backflux between oxaloacetate and fumarate following pyruvate carboxylation
Brekke, E., Walls, Anne Byriel, Nørfeldt, L., Schousboe, Arne, Waagepetersen, Helle S. & Sonnewald, U., 2012, In: Glia. 60, 1, p. 147-58 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Distinct differences in rates of oxygen consumption and ATP synthesis of regionally isolated non-synaptic mouse brain mitochondria
Andersen, Jens Velde, Jakobsen, Emil, Waagepetersen, Helle S. & Aldana, Blanca, 2019, In: Journal of Neuroscience Research. 97, p. 961–974Research output: Contribution to journal › Journal article › Research › peer-review
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Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease
Salcedo, C., Wagner, A., Andersen, Jens Velde, Vinten, K. T., Waagepetersen, Helle S., Schousboe, Arne, Freude, Kristine & Aldana, Blanca, 2021, In: Neurochemical Research. 46, p. 2676–2686Research output: Contribution to journal › Journal article › Research › peer-review
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Dual Properties of Lactate in Müller Cells: The Effect of GPR81 Activation
Vohra, Rupali, Aldana, Blanca, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Mar 2019, In: Investigative Ophthalmology & Visual Science. 60, 4, p. 999-1008 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamic changes in cytosolic ATP levels in cultured glutamatergic neurons during NMDA-induced synaptic activity supported by glucose or lactate
Lange, S. C., Winkler, U., Andresen, Lars, Byhrø, M., Waagepetersen, Helle S., Hirrlinger, J. & Bak, Lasse Kristoffer, Dec 2015, In: Neurochemical Research. 40, 12, p. 2517-2526 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dysfunctional TCA-Cycle Metabolism in Glutamate Dehydrogenase Deficient Astrocytes
Nissen, J. D., Pajęcka, K., Stridh, M. H., Jensen, Dorte Skytt & Waagepetersen, Helle S., Dec 2015, In: Glia. 63, 12, p. 2313-26 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of glutamine synthetase inhibition on brain and interorgan ammonia metabolism in bile duct ligated rats
Fries, A. W., Dadsetan, S., Keiding, S., Bak, Lasse Kristoffer, Schousboe, Arne, Waagepetersen, Helle S., Simonsen, M., Ott, P., Vilstrup, H. & Sørensen, M., Mar 2014, In: Journal of Cerebral Blood Flow and Metabolism. 34, 3, p. 460-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of adrenergic agents on intracellular ca(2+) homeostasis and metabolism of glucose in astrocytes with an emphasis on pyruvate carboxylation, oxidative decarboxylation and recycling: implications for glutamate neurotransmission and excitotoxicity
Obel, L. L. F., Andersen, K. M. H., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2012, In: Neurotoxicity Research. 21, 4, p. 405-17 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of diabetes on brain metabolism - is brain glycogen a significant player?
Sickmann, H. M. & Waagepetersen, Helle S., 2015, In: Metabolic Brain Disease. 30, p. 335-343 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of hyperammonemia on brain energy metabolism: controversial findings in vivo and in vitro
Schousboe, Arne, Waagepetersen, Helle S., Leke, R. & Bak, Lasse Kristoffer, 1 Mar 2014, In: Metabolic Brain Disease. 29, 4, p. 913-917 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of ketone bodies in Alzheimer's disease in relation to neural hypometabolism, β-amyloid toxicity, and astrocyte function
Hertz, L., Chen, Y. & Waagepetersen, Helle S., Jul 2015, In: Journal of Neurochemistry. 134, 1, p. 7-20 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Energy Metabolism of the Brain
McKenna, M. C., Dienel, G. A., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, 1 Dec 2012, Basic Neurochemistry. Elsevier, p. 200-231 32 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Energy substrates to support glutamatergic and GABAergic synaptic function: role of glycogen, glucose and lactate
Schousboe, Arne, Bak, Lasse Kristoffer, Sickmann, H. M., Sonnewald, U. & Waagepetersen, Helle S., Dec 2007, In: Neurotoxicity Research. 12, 4, p. 263-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Energy substrates to support glutamatergic and GABAergic synaptic function: Role of glycogen, glucose and lactate
Schousboe, Arne, Bak, Lasse Kristoffer, Sickmann, H. M., Sonnewald, U. & Waagepetersen, Helle S., 2007, In: Neurotoxicity Research. 12, 4, p. 263-268Research output: Contribution to journal › Journal article › Research › peer-review
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Enhanced cerebral branched-chain amino acid metabolism in R6/2 mouse model of Huntington's disease
Andersen, Jens Velde, Skotte, Niels Henning, Aldana, Blanca, Nørremølle, Anne & Waagepetersen, Helle S., 2019, In: Cellular and Molecular Life Sciences. 76, 12, p. 2449-2461Research output: Contribution to journal › Journal article › Research › peer-review
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Epigallocatechin-3-gallate (EGCG) activates AMPK through the inhibition of glutamate dehydrogenase in muscle and pancreatic ß-cells: A potential beneficial effect in the pre-diabetic state?
Pournourmohammadi, S., Grimaldi, M., Stridh, M. H., Lavallard, V., Waagepetersen, Helle S., Wollheim, C. B. & Maechler, P., 1 Jul 2017, In: The International Journal of Biochemistry & Cell Biology. 88, p. 220-225Research output: Contribution to journal › Journal article › Research › peer-review
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Erratum: Demonstration of neuron-glia transfer of precursors for gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex (Neurochem Res (2008) 33:26292635;DOI 10.1007/s11064-008-9814-6)
Leke, R., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 1 Dec 2009, In: Neurochemical Research. 34, 12, 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
ID: 983216
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Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B
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Lactate-Mediated Protection of Retinal Ganglion Cells
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Distinct differences in rates of oxygen consumption and ATP synthesis of regionally isolated non-synaptic mouse brain mitochondria
Research output: Contribution to journal › Journal article › Research › peer-review
Published