Bo Torben Porse
Professor, Clinical Professor
Porse Group
Københavns Universitet, BRIC, Ole Maaløes Vej 5
2200 København N
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Member of:
Internal Medicine: Haematology
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Immunophenotypical characterization of human neutrophil differentiation
Jensen, H. M., Jendholm, J., Fossum, A., Porse, Bo Torben, Borregaad, N. & Theilgaard-Mønch, Kim, 7 Jun 2011, In: Journal of Leukocyte Biology. p. 629-634 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improving The Analysis Of Gene Expression Profiles By Comparing AML Blasts With Their Nearest Normal Counterparts
Rapin, N., Bagger, F. O., Jendholm, J., Mora-Jensen, H. I., Krogh, Anders, Kohlmann, A., Thiede, C., Borregaard, N., Bullinger, L., Winther, Ole, Theilgaard-Mønch, Kim & Porse, Bo Torben, 2013, In: Blood. 122, 21Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response
Johnson, J. L., Stoica, L., Liu, Y., Zhu, P. J., Bhattacharya, A., Buffington, S., Huq, R., Eissa, N. T., Larsson, O., Porse, B. T., Domingo, D., Nawaz, U., Carroll, R., Jolly, L., Scerri, T. S., Kim, H-G., Brignell, A., Coleman, M. J., Braden, R., Kini, U. & 11 others, , 2019, In: Neuron. 104, 4, p. 665-679 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Initiation of MLL-rearranged AML is dependent on C/EBPα
Ohlsson, E., Hasemann, M. S., Willer, A., Lauridsen, F. K. B., Rapin, N. P. J., Jendholm, L. J. & Porse, Bo Torben, 13 Jan 2014, In: The Journal of Experimental Medicine. 211, 1, p. 5-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Integrative analysis of histone ChIP-seq and transcription data using Bayesian mixture models
Klein, H., Schäfer, M., Porse, Bo Torben, Hasemann, M. S., Ickstadt, K. & Dugas, M., 22 Jan 2014, In: Bioinformatics.Research output: Contribution to journal › Journal article › Research › peer-review
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Inter and transgenerational impact of H3K4 methylation in neuronal homeostasis
Nørgaard, Steffen, Tapia, Marta Cecylia, Zeijdner, Mandoh Johannes Seydin, Kim, J. H., Won, K. J., Porse, Bo Torben & Salcini, Anna Elisabetta, 2023, In: Life Science Alliance. 6, 8, 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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LEP promoter methylation in the initiation and progression of clonal cytopenia of undetermined significance and myelodysplastic syndrome
Kaastrup, K., Gillberg, Linn, Mikkelsen, Stine Ulrik, mxz703, mxz703, Schöllkopf, C., Mortensen, B. K., Porse, Bo Torben, Hansen, Jakob Werner & Grønbæk, Kirsten, 2023, In: Clinical Epigenetics. 15, 13 p., 91.Research output: Contribution to journal › Journal article › Research › peer-review
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Lack of the p42 form of C/EBPα leads to spontaneous immortalization and lineage infidelity of committed myeloid progenitors
Schuster, Mikkel Bruhn, Frank, Anne-Katrine, Bagger, F. O., Rapin, N., Vikesaa, J. & Porse, Bo Torben, Oct 2013, In: Experimental Hematology. 41, 10, p. 882-893 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leukemia - methods and protocols
Porse, Bo Torben, 2009, In: European Journal of Haematology. 84, 1, p. 94Research output: Contribution to journal › Journal article › Research › peer-review
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Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates
Gu, X., Ebrahem, Q., Mahfouz, R. Z., Hasipek, M., Enane, F., Radivoyevitch, T., Rapin, N., Przychodzen, B., Hu, Z., Balusu, R., Cotta, C. V., Wald, D., Argueta, C., Landesman, Y., Martelli, M. P., Falini, B., Carraway, H., Porse, B. T., Maciejewski, J., Jha, B. K. & 1 others, , 2018, In: The Journal of Clinical Investigation. 128, 10, p. 4260-4279 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipocalin 2 is protective against E. coli pneumonia
Wu, H., Santoni-Rugiu, E., Ralfkiaer, E., Porse, Bo Torben, Moser, Claus Ernst, Høiby, Niels, Borregaard, N. & Cowland, J. B., 2010, In: Respiratory research. 11, p. 96Research output: Contribution to journal › Journal article › Research › peer-review
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Lipocalin 2 is protective against E. coli pneumonia
Wu, H., Santoni Rugiu, Eric, Ralfkiaer, E., Porse, Bo Torben, Moser, C., Høiby, Niels, Borregaard, N., Cowland, J. B., Wu, H., Santoni Rugiu, Eric, Ralfkiær, E., Porse, B. T., Moser, C. E., Høiby, N., Borregaard, N. & Cowland, J., 15 Jun 2010, In: Respiratory research (Online). 11, 96, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Liver is the major source of elevated serum lipocalin-2 levels after bacterial infection or partial hepatectomy: A critical role for IL-6/STAT3
Xu, M., Feng, D., Wu, H., Wang, H., Chan, Y., Kolls, J., Borregaard, N., Porse, Bo Torben, Berger, T., Mak, T. W., Cowland, J. B., Kong, X. & Gao, B., Feb 2015, In: Hepatology. 61, 2, p. 692-702 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage.
Porse, Bo Torben, Bryder, D., Theilgaard-Mønch, Kim, Hasemann, M. S., Anderson, K., Damgaard, I., Jacobsen, S. E. W. & Nerlov, C., 2005, In: Journal of Experimental Medicine. 202, 1, p. 85-96 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis
Rasmussen, K. D., Jia, G., Johansen, Jens Vilstrup, Pedersen, M. T., Rapin, N., Bagger, F. O., Porse, Bo Torben, Bernard, O. A., Christensen, J. & Helin, K., 17 Apr 2015, In: Genes & Development. p. 910-922 13 p., 29.Research output: Contribution to journal › Journal article › Research › peer-review
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Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns
Weischenfeldt, Joachim Lütken, Waage, J. E., Tian, G., Zhao, J., Damgaard, I., Jakobsen, J. S., Kristiansen, Karsten, Krogh, Anders, Wang, J. & Porse, Bo Torben, 2012, In: Genome Biology (Online Edition). 13, 5, 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mapping important nucleotides in the peptidyl transferase centre of 23 S rRNA using a random mutagenesis approach.
Porse, Bo Torben & Garrett, R. A., 1995, In: Journal of Molecular Biology. 249, 1, p. 1-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Messenger RNA surveillance: neutralizing natural nonsense.
Weischenfeldt, Joachim Lütken, Lykke-Andersen, J. & Porse, Bo Torben, 2005, In: Current Biology. 15, 14, p. R559-62Research output: Contribution to journal › Journal article › Research › peer-review
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Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.
Kirstetter, P., Schuster, Mikkel Bruhn, Bereshchenko, O., Moore, S., Dvinge, H., Kurz, E., Theilgaard-Mønch, Kim, Månsson, R., Pedersen, T. A., Pabst, T., Schrock, E., Porse, Bo Torben, Jacobsen, S. E. W., Bertone, P., Tenen, D. G. & Nerlov, C., 2008, In: Cancer Cell. 13, 4, p. 299-310 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Movement of the 3'-end of tRNA through the peptidyl transferase centre and its inhibition by antibiotics
Kirillov, S., Porse, Bo Torben, Vester, B., Woolley, P. & Garrett, Roger Antony, 1997, In: FEBS Letters. 406, 3, p. 223-233 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target
Vanner, R. J., Dobson, S. M., Gan, O. I., McLeod, J., Schoof, E. M., Grandal, I., Wintersinger, J. A., Garcia-Prat, L., Hosseini, M., Xie, S. Z., Jin, L., Mbong, N., Voisin, V., Chan-Seng-Yue, M., Kennedy, J. A., Waanders, E., Morris, Q., Porse, B., Chan, S. M., Guidos, C. J. & 4 others, , 2022, In: Blood cancer discovery. 3, 1, p. 16-31 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML
Jakobsen, J. S., Laursen, L. G., Schuster, Mikkel Bruhn, Pundhir, Sachin, Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mønch, Kim, Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. & Porse, Bo Torben, 2019, In: Science Advances. 5, 7, p. 1-16 16 p., eaaw4304.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutation of C/EBPalpha predisposes to the development of myeloid leukemia in a retroviral insertional mutagenesis screen.
Hasemann, M. S., Damgaard, I., Schuster, Mikkel Bruhn, Theilgaard-Mønch, Kim, Sørensen, A. B., Mrsic, A., Krugers, T., Ylstra, B., Pedersen, F. S., Nerlov, C. & Porse, Bo Torben, 2008, In: Blood. 111, 8, p. 4309-21 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myelodysplastic syndrome patient-derived xenografts: from no options to many
Côme, Christophe Roger Michel, Balhuizen, Alexander, Bonnet, D. & Porse, Bo Torben, 2020, In: Haematologica. 105, 4, p. 864-869Research output: Contribution to journal › Journal article › Research › peer-review
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NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.
Weischenfeldt, Joachim Lütken, Damgaard, I., Bryder, D., Theilgaard-Mønch, Kim, Thoren, L. A., Nielsen, F. C., Jacobsen, S. E. W., Nerlov, C. & Porse, Bo Torben, 2008, In: Genes & Development. 22, 10, p. 1381-96 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4985646
Most downloads
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3495
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spliceR: an R package for classification of alternative splicing and prediction of coding potential from RNA-seq data
Research output: Contribution to journal › Journal article › Research › peer-review
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2750
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Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2496
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HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
Research output: Contribution to journal › Journal article › Research › peer-review
Published