Niels Erik Skakkebæk

Niels Erik Skakkebæk

Affiliate Professor

Member of:

  • Paediatrics


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  1. Published

    Caffeine intake and semen quality in a population of 2,554 young Danish men

    Jensen, T. K., Swan, S. H., Skakkebæk, Niels Erik, Rasmussen, S. & Jørgensen, N., 15 Apr 2010, In: American Journal of Epidemiology. 171, 8, p. 883-91 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Carcinoma in situ in the testis

    Rørth, M., Rajpert-De Meyts, E., Andersson, L., Dieckmann, Peter, Fosså, S. D., Grigor, K. M., Hendry, W. F., Herr, H. W., Looijenga, L. H., Oosterhuis, J. W. & Skakkebæk, Niels Erik, 2000, In: Scandinavian Journal of Urology and Nephrology, Supplementum. 205, p. 166-86 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Carcinoma in situ of contralateral testis in patients with testicular germ cell cancer: study of 27 cases in 500 patients

    von der Maase, H., Rørth, M., Walbom-Jørgensen, S., Sørensen, B. L., Christophersen, I. S., Hald, Tine Marianne, Jacobsen, G. K., Berthelsen, Jens & Skakkebæk, Niels Erik, 1986, In: British medical journal (Clinical research ed.). 293, 6559, p. 1398-401 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells

    Almstrup, Kristian, Nielsen, J. E., Mlynarska, O., Jansen, M. T., Jørgensen, A., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., 12 Oct 2010, In: British Journal of Cancer. 103, 8, p. 1269-76 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Cardiovascular risk factors in men: The role of gonadal steroids and sex hormone-binding globulin

    Gyllenborg, J., Rasmussen, S. L., Borch-Johnsen, K., Heitmann, B. L., Skakkebæk, Niels Erik & Juul, Anders, 2001, In: Metabolism. 50, 8, p. 882-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Central Precocious Puberty in two Boys with Prader-Willi Syndrome on Growth Hormone Treatment

    Monai, E., Johansen, A., Clasen-Linde, E., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Main, Katharina Maria, Jørgensen, A. & Jensen, R. B., 2019, In: AACE Clinical Case Reports. 5, 6, p. e352-e356

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Changes in Anti-Mullerian Hormone (AMH) throughout the Life Span: A Population-Based Study of 1027 Healthy Males from Birth (Cord Blood) to the Age of 69 Years

    Aksglæde, L., Sørensen, K., Boas, M., Mouritsen, Annette Korsholm, Hagen, C. P., Jensen, R. B., Petersen, J. H., Linneberg, Allan René, Andersson, A. M., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5357-5364 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Changes in Anti-Müllerian Hormone (AMH) throughout the Life Span: A Population-Based Study of 1027 Healthy Males from Birth (Cord Blood) to the Age of 69 Years

    Aksglæde, L., Sørensen, K., Boas, M., Mouritsen, A. K. M., Hagen, C., Jensen, R., Petersen, Jørgen Holm, Linneberg, Allan René, Andersson, A., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5357-5364 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Changes in anti-Müllerian hormone (AMH) throughout the life span: a population-based study of 1027 healthy males from birth (cord blood) to the age of 69 years

    Aksglaede, L., Sørensen, K., Boas, M., Mouritsen, A., Hagen, C. P., Jensen, R. B., Petersen, J. H., Linneberg, Allan René, Andersson, A., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5357-64 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Changes in semen and the testis

    Skakkebæk, Niels Erik & Keiding, N., 19 Nov 1994, In: BMJ. 309, 6965, p. 1316-1317 2 p.

    Research output: Contribution to journal › Editorial › Research

  11. Published

    Changes in serum concentrations of growth hormone, insulin, insulin-like growth factor and insulin-like growth factor-binding proteins 1 and 3 and urinary growth hormone excretion during the menstrual cycle

    Juul, Anders, Scheike, T. H., Pedersen, Anette Tønnes, Main, Katharina Maria, Andersson, A. M., Pedersen, L. M. & Skakkebæk, Niels Erik, 1997, In: Human Reproduction. 12, 10, p. 2123-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation

    Rajpert-De Meyts, E., Poll, S. N., Goukasian, I., Jeanneau, C., Herlihy, A. S., Bennett, Eric Paul, Skakkebæk, Niels Erik, Clausen, Henrik, Giwercman, A. & Mandel, Ulla, 2007, In: Virchows Archiv. 451, 4, p. 805-14 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Changes in urinary excretion of phthalates, phthalate substitutes, bisphenols and other polychlorinated and phenolic substances in young Danish men: 2009–2017

    Frederiksen, H., Nielsen, O., Koch, H. M., Skakkebæk, Niels Erik, Juul, Anders, Jørgensen, N. & Andersson, A. M., Jan 2020, In: International Journal of Hygiene and Environmental Health. 223, 1, p. 93-105

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Characterisation and localisation of the endocannabinoid system components in the adult human testis

    Nielsen, J. E., Rolland, A. D., Rajpert-De Meyts, E., Janfelt, Christian, Jørgensen, A., Winge, S. B., Kristensen, D. M., Juul, Anders, Chalmel, F., Jégou, B. & Skakkebæk, Niels Erik, 2019, In: Scientific Reports. 9, 1, 14 p., 12866.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Chemical UV Filters Mimic the Effect of Progesterone on Ca(2+) Signaling in Human Sperm Cells

    Rehfeld, Anders Aagaard, Dissing, Steen & Skakkebæk, Niels Erik, Nov 2016, In: Endocrinology. 157, 11, p. 4297-4308 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth

    Boas, M., Frederiksen, H., Feldt-Rasmussen, Ulla, Skakkebæk, Niels Erik, Hegedüs, L., Hilsted, L. M., Juul, Anders & Main, Katharina Maria, 1 Oct 2010, In: Environmental Health Perspectives. 118, 10, p. 1458-64 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Chromosome-wise Protein Interaction Patterns and Their Impact on Functional Implications of Large-Scale Genomic Aberrations

    Kirk, I. K., Weinhold, N., Belling, K., Skakkebæk, Niels Erik, Jensen, T. S., Leffers, H., Juul, Anders & Brunak, Søren, 22 Mar 2017, In: Cell Systems. 4, 3, 11 p., 357-364.e3.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Clinical and biological parameters in 166 boys, adolescents and adults with nonmosaic Klinefelter syndrome: a Copenhagen experience

    Aksglaede, L., Skakkebæk, Niels Erik, Almstrup, Kristian & Juul, Anders, 1 Jun 2011, In: Acta Paediatrica. 100, 6, p. 793-806 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Clinical, genetic, biochemical, and testicular biopsy findings among 1,213 men evaluated for infertility

    Olesen, I. A., Andersson, A., Aksglaede, L., Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Jørgensen, N. & Juul, Anders, Jan 2017, In: Fertility and Sterility. 107, 1, p. 74-82.e7

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Commentary: sperm counts, data responsibility, and good scientific practice

    Skakkebæk, Niels Erik, Andersson, A., Juul, Anders, Jensen, T. K., Almstrup, Kristian, Toppari, J. & Jørgensen, N., 1 Sep 2011, In: Epidemiology. 22, 5, p. 620-1 2 p.

    Research output: Contribution to journal › Letter › Research

  21. Published

    Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents

    Lottrup, G., Belling, K., Leffers, H., Nielsen, J. E., Dalgaard, M. D., Juul, Anders, Skakkebæk, Niels Erik, Brunak, Søren & Meyts, E. R., 1 May 2017, In: Molecular Human Reproduction. 23, 5, p. 339-354 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Compensated reduction in Leydig cell function is associated with lower semen quality variables: A study of 8182 European young men

    Jørgensen, N., Joensen, Ulla Nordström, Toppari, J., Punab, M., Erenpreiss, J., Zilaitiene, B., Paasch, U., Salzbrunn, A., Fernandez, M. F., Virtanen, H. E., Matulevicius, V., Olea, N., Jensen, T. K., Petersen, Jørgen Holm, Skakkebæk, Niels Erik & Andersson, A. M., 1 May 2016, In: Human Reproduction. 31, 5, p. 947-957 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Concentrations of persistent organochlorine compounds in human milk and placenta are higher in Denmark than in Finland

    Shen, H., Main, K. M., Andersson, A. M., Damgaard, I. N., Virtanen, H. E., Toppari, J., Schramm, K. W. & Skakkebæk, Niels Erik, 2008, In: Human Reproduction. 23, 1, p. 201-210 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Consequences of stopping Growth hormone (GH) therapy in young GH-deficient patients with childhood-onset disease

    Juul, Anders, Vahl, N., Jørgensen, J., Christiansen, J. & Skakkebæk, Niels Erik, 1998, In: Growth Hormone & I G F Research. p. 15-19 4 p.

    Research output: Contribution to journal › Review › Research

  25. Published

    Continuation of growth hormone (GH) therapy in GH-deficient patients during transition from childhood to adulthood: impact on insulin sensitivity and substrate metabolism

    Nørrelund, H., Vahl, N., Juul, Anders, Møller, N., Alberti, K. G., Skakkebæk, Niels Erik, Christiansen, J. S. & Jørgensen, J. O., 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, 5, p. 1912-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Continuation of growth hormone therapy versus placebo in transition-phase patients with growth hormone deficiency: impact on body composition, insulin sensitivity, and thyroid function

    Jørgensen, J., Nørrelund, H., Vahl, N., Juul, Anders, Skakkebæk, Niels Erik & Christiansen, J. S., 2002, In: Journal of Pediatric Endocrinology and Metabolism. 15 Suppl 5, p. 1355-60 6 p.

    Research output: Contribution to journal › Journal article › Research

  27. Published

    Contralateral biopsy in the management of testicular cancer: what we have learned and what we need to improve

    Rørth, M., Grigor, K. M., Jørgensen, N., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., Jan 2015, In: Andrology. 3, 1, p. 99-101 3 p.

    Research output: Contribution to journal › Editorial › Research

  28. Published

    Cotinine concentrations in maternal serum and amniotic fluid during pregnancy and risk of testicular germ cell cancer in the offspring: A prospective nested case-control study

    Beck, A. L., Uldbjerg, C. S., Lim, Youn-Hee, Coull, B. A., Sørensen, K. M., Utko, M. M., Wilkowski, B., Rantakokko, P., Bengtsson, M., Lindh, C., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Hauser, R., Juul, Anders & Bräuner, E. V., 2023, In: International Journal of Cancer. 154, 1, p. 71-80 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Country-specific chemical signatures of persistent environmental compounds in breast milk

    Krysiak-Baltyn, K., Toppari, J., Skakkebaek, N. E., Jensen, T. S., Virtanen, H. E., Schramm, K-W., Shen, H., Vartiainen, T., Kiviranta, H., Taboureau, O., Brunak, S., Main, K. M., Krysiak-Baltyn, K., Toppari, J., Skakkebaek, N. E., Jensen, T. S., Virtanen, H. E., Schramm, K-W., Shen, H., Vartiainen, T. & 4 others, Kiviranta, H., Taboureau, O., Brunak, S. & Main, Katharina Maria, 1 Apr 2010, In: International Journal of Andrology. 33, 2, p. 270-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Country-specific chemical signatures of persistent organic pollutants (POPs) in breast milk of French, Danish and Finnish women

    Antignac, J. P., Main, Katharina Maria, Virtanen, H. E., Boquien, C. Y., Marchand, P., Venisseau, A., Guiffard, I., Bichon, E., Wohlfahrt-Veje, C., Legrand, S., Boscher, C., Skakkebæk, Niels Erik, Toppari, J. & Le Bizec, B., Nov 2016, In: Environmental Pollution. 218, p. 728-738 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Cryptorchidism and hypospadias as a sign of testicular dysgenesis syndrome (TDS): environmental connection

    Toppari, J., Virtanen, H. E., Main, Katharina Maria & Skakkebæk, Niels Erik, 1 Oct 2010, In: Birth Defects Research. Part A: Clinical and Molecular Teratology. 88, 10, p. 910-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Cryptorchidism as part of the testicular dysgenesis syndrome: the environmental connection

    Main, Katharina Maria, Skakkebæk, Niels Erik & Toppari, J., 2009, In: Endocrine Development. 14, p. 167-73 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Cryptorchidism, hypospadias, testicular tumours and testicular dysgenesis syndrome

    Rajpert-De Meyts, E., Main, Katharina Maria, Toppari, J. & Skakkebæk, Niels Erik, 2010, Endocrinology.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  34. Published

    Den prognostiske værdi af insulinlignende vækstfaktor i (IGF-I) og bindingsproteinet IGFBP-3 ved alkoholistisk leversygdom

    Møller, S., Becker, U., Juul, Anders, Skakkebæk, Niels Erik, Christensen, E. & EMALD-gruppen, E., 1997, In: Ugeskrift for Laeger. 159, 30, p. 4636-4640 4 p.

    Research output: Contribution to journal › Journal article › Research

  35. Published

    Determination of thyroid hormones in placenta using isotope-dilution liquid chromatography quadrupole time-of-flight mass spectrometry

    Li, Z., Giesert, F., Vogt-Weisenhorn, D., Main, Katharina Maria, Skakkebæk, Niels Erik, Kiviranta, H., Toppari, J., Feldt-Rasmussen, Ulla, Shen, H., Schramm, K. & De Angelis, M., 2018, In: Journal of Chromatography A. 1534, p. 85-92

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Development and descent of the testis in relation to cryptorchidism

    Virtanen, H. E., Cortes, Dina, Rajpert-De Meyts, E., Ritzén, E. M., Nordenskjöld, A., Skakkebæk, Niels Erik & Toppari, J., 1 May 2007, In: Acta Paediatrica. 96, 5, p. 622-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Development: disorders of sex development-the tip of the iceberg?

    Juul, Anders, Main, Katharina Maria & Skakkebæk, Niels Erik, 1 Jan 2011, In: Nature Reviews Endocrinology. 7, 9, p. 504-5 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Developmental origins of testicular germ cell tumours (TGCT)

    Meyts, E. R., Jørgensen, A., Jørgensen, N., Almstrup, Kristian & Skakkebæk, Niels Erik, Sep 2019, In: European Urology Supplements. 18, 4, p. 11

    Research output: Contribution to journal › Conference abstract in journal › Research

  39. Published

    Diagnosis of GH deficiency and use of GH in children with growth disorders. A report from the Drugs and Therapeutics Committee of European Society for paediatric Endocrinology

    Juul, Anders, Bernasconi, S., Chatelain, P., Hindsmarsh, P., Hochberg, Z., Hokke-Koelega, A., De Muinck Keizer-Schrama, S., Kiess, W., Oberfield, S., Strasburger, C., Volta, C., Westphal, O. & Skakkebæk, Niels Erik, 1999, In: Hormone Research. 51, p. 284-299 15 p.

    Research output: Contribution to journal › Review › Research

  40. Diagnostic markers for germ cell neoplasms: From placental-like alkaline phosphatase to micro-RNAs

    Meyts, E. R. D., Nielsen, J. E., Skakkebæk, Niels Erik & Almstrup, Kristian, 8 Oct 2015, In: Folia Histochemica et Cytobiologica. 53, 3, p. 177-188 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Diminished concentrations of insulin-like growth factor I in cystic fibrosis

    Laursen, E., Juul, Anders, Lanng, S., Høiby, N., Koch, C., Müller, J. & Skakkebæk, Niels Erik, 1995, In: Archives of Disease in Childhood. Education and Practice Edition. 72, 6, p. 494-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Direct action of endocrine disrupting chemicals on human sperm

    Schiffer, C., Müller, A., Egeberg, D. L., Alvarez, L., Brenker, C., Rehfeld, Anders Aagaard, Frederiksen, H., Wäschle, B., Kaupp, U. B., Balbach, M., Wachten, D., Skakkebæk, Niels Erik, Almstrup, Kristian & Strünker, T., Jul 2014, In: E M B O Reports. 15, 7, p. 758-65 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Disorders of sexual differentiation-the tip of the iceberg?

    Juul, Anders, Main, Katharina Maria & Skakkebæk, Niels Erik, 2011, In: Nature Reviews Endocrinology. 7, p. 504-5 1 p.

    Research output: Contribution to journal › Letter › Research

  44. Published

    Distinguishing between hidden testes and anorchia: The role of endocrine evaluation in infancy and childhood

    Jespersen, K., Ljubicic, M. L., Johannsen, T. H., Christiansen, P., Skakkebæk, Niels Erik & Juul, Anders, 2020, In: European Journal of Endocrinology. 183, 1, p. 107-117 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Do environmental estrogens contribute to the decline in male reproductive health?

    Jensen, T. K., Toppari, J., Keiding, N. & Skakkebæk, Niels Erik, Dec 1995, In: Clinical Chemistry. 41, 12, p. 1896-1901 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Do environmental factors play a role in the aetiology of carcinoma in situ testis and the testicular dysgenesis syndrome?

    Sonne, Si Brask, Hoei-Hansen, C. E., Fisher, J. S., Leffers, H., Rajpert-de Meyts, E. & Skakkebæk, Niels Erik, 2004, In: Verhandlungen der Deutschen Gesellschaft fur Pathologie. 88, p. 144-51 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Do perfluoroalkyl compounds impair human semen quality?

    Joensen, Ulla Nordström, Bossi, R., Leffers, H., Jensen, A. A., Skakkebæk, Niels Erik & Jørgensen, N., 2009, In: Environmental Health Perspectives. 117, 6, p. 923-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Does breast feeding influence liver biochemistry?

    Jørgensen, M. H., Ott, P., Juul, Anders, Skakkebæk, Niels Erik & Michaelsen, K. F., 2003, In: Journal of Pediatric Gastroenterology and Nutrition. 37, 5, p. 559-65 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner

    Rehfeld, Anders Aagaard, Egeberg, D., Almstrup, Kristian, Petersen, Jørgen Holm, Dissing, Steen & Skakkebæk, Niels Erik, 2018, In: Endocrine Connections. 7, 1, p. 16-25

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Early Life Events Predict Adult Testicular Function: Data Derived From the Western Australian (Raine) Birth Cohort

    Hart, R. J., Doherty, D. A., Keelan, J. A., McLachlan, R., Skakkebæk, Niels Erik, Norman, R. J., Dickinson, J. E., Pennell, C. E., Newnham, J. P., Hickey, M. & Handelsman, D. J., Sep 2016, In: The Journal of clinical endocrinology and metabolism. 101, 9, p. 3333-3344 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 35319116